immune disorders
Hyper IgM Syndrome
Diagnosis of Hyper IgM Syndrome
Blood tests Genetic testing Doctors suspect hyper-IgM syndrome based on symptoms. They then measure levels of immunoglobulins. High or normal levels of IgM and low levels or absence of other immunoglobulins support the diagnosis. When possible, the diagnosis is confirmed by genetic testing. Prenatal Diagnostic Testing can be offered to women considering pregnancy if they have family members with certain gene mutations that can cause hyper-IgM syndrome. 