gynecology and obstetrics
Preeclampsia and Eclampsia
Etiology of Preeclampsia and Eclampsia
Etiology of preeclampsia is unknown. However, high-risk and moderate-risk factors have been identified ( Etiology references ). High-risk factorsinclude Previous pregnancy with preeclampsia Multifetal gestation Kidney disorders Autoimmune disorders Type 1 or type 2 diabetes mellitus Chronic hypertension Moderate-risk factorsinclude First pregnancy Maternal age ≥ 35 Body mass index > 30 Family history of preeclampsia Sociodemographic characteristics (African American race, low socioeconomic status) Personal history factors (eg, previous infants with low birth weight or small for gestational age, previous adverse pregnancy outcome, > 10-year pregnancy interval [ Etiology references ]) 1.Henderson JT, Whitlock EP, O'Conner E, et al: Table 8: Preeclampsia Risk Factors Based on Patient Medical History inLow-doseaspirinfor the prevention of morbidity and mortality from preeclampsia: A systematic evidence review for the U.S. Preventive Services Task Force. Rockville (MD): Agency for Healthcare Research and Quality (US), 2014 2.American College of Obstetricians and Gynecologists (ACOG): Gestational hypertension and preeclampsia: ACOG Practice Bulletin, Number 222.Obstet Gynecol135 (6):e237–e260, 2020. 