infectious diseases
Mucormycosis
Treatment of Mucormycosis
Control of underlying condition Lipidamphotericin Bformulations Isavuconazonium Surgical debridement (See also Antifungal Medications .) Effective therapy requires that diabetes be controlled or, if at all possible, immunosuppression be reversed ordeferoxaminebe stopped. A high-dose lipidamphotericin Bformulation (7.5 to 10 mg/kg IV once a day) is recommended as initial therapy.Isavuconazoniumis approved for primary therapy. However, clinical experience withisavuconazoniumis relatively limited, and, in severely ill patients,amphotericin Blikely remains the medication of choice.Posaconazolemay also be effective, especially as consolidation therapy.Posaconazolehas not been studied as primary therapy. Complete surgical debridement of necrotic tissue is critical. 