bone, joint, and muscle disorders
Ankylosing Spondylitis
Treatment of Ankylosing Spondylitis
Nonsteroidal anti-inflammatory drugs Sulfasalazine,methotrexate, tumor necrosis factor inhibitors, andsecukinumaborixekizumab Exercise Treatment of ankylosing spondylitis is focused on Relieving back and joint pain Maintaining range of motion in the joints Preventing damage in other organs Preventing or correcting spinal deformities Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) can reduce pain and inflammation, thus enabling people to do important exercises to retain posture, including stretching and deep breathing. for the treatment of ankylosing spondylitis in people with recurring Uveitis . Secukinumab, an interleukin-17A receptor antagonist, can also reduce inflammation and joint symptoms.Ixekizumab, another interleukin-17 inhibitor, is used for active ankylosing spondylitis. The long-range goals of ankylosing spondylitis treatment are to maintain proper posture and develop strong back muscles. Daily exercises strengthen the muscles that oppose the tendency to bend and stoop. It has been suggested that people spend some time each day—often while reading—lying on their stomach propped up on their elbows because this position extends the back and helps to keep the back flexible. Corticosteroid eye drops and dilating eye drops may help in the short-term treatment of inflammation of the eyes that comes and goes, and an occasional corticosteroid injection may be helpful for 1 or 2 joints other than the spine. Muscle relaxants and opioid analgesics are occasionally used, but for only brief periods to relieve severe pain and muscle spasms. If the hips become eroded or fixed in a bent position, surgical treatment to replace the joint can relieve pain and restore function. Because chest wall motion can be restricted, which impairs lung function, cigarette smoking, which also impairs lung function, is strongly discouraged. 