gastrointestinal disorders
Stomach Cancer
Pathophysiology of Stomach Cancer
Gastric adenocarcinomas can be classified by gross appearance: Protruding: The tumor is polypoid or fungating. Penetrating: The tumor is ulcerated. Superficial spreading: The tumor spreads along the mucosa or infiltrates superficially within the wall of the stomach. Linitis plastica: The tumor infiltrates the stomach wall with an associated fibrous reaction that causes a rigid “leather bottle” stomach. Miscellaneous: The tumor shows characteristics of≥2 of the other types; this classification is the largest. Prognosis is better with protruding tumors than with spreading tumors because protruding tumors become symptomatic earlier. 