hematology and oncology
Antiphospholipid Syndrome (APS)
Treatment of Antiphospholipid Syndrome
Anticoagulation is the standard approach ( Treatment reference ). Higher rates of recurrent thromboembolism with DOACs have been noted, so these medications should not be used for treatment of thrombotic APS. Unfractionatedheparinor low molecular weightheparinplus low-doseaspirinis used during pregnancy to prevent recurrent pregnancy losses in women with APS. After delivery, unfractionatedheparinor low molecular weightheparinis continued for 6 weeks for thromboprophylaxis. 1.Garcia D, Erkan D. Diagnosis and Management of the Antiphospholipid Syndrome. N Engl J Med. 2018;378(21):2010-2021. doi:10.1056/NEJMra1705454 