bone, joint, and muscle disorders
Calcium Pyrophosphate (CPP) Arthritis
Causes of CPP Arthritis
The reason that CPP dihydrate crystals form in some people is unknown. The crystals often occur in people who have the following: A previous joint injury (including surgery) Gout None Accumulations of an abnormal protein in various organs and tissues ( Amyloidosis ) ( Hyperparathyroidism ) An abnormally high iron level in the tissues ( Hemochromatosis ) An abnormally low magnesium level in the blood ( Hypomagnesemia (Low Level of Magnesium in the Blood) ) Certain rare disorders including hypophosphatasia, Bartter Syndrome and Gitelman Syndrome , Older age However, many people with CPP arthritis have none of these conditions. The disorder rarely can be hereditary. Calcium crystals can frequently occur in joints affected by Osteoarthritis (OA) for unclear reasons. However, calcium deposits in a joint may not cause symptoms. 