infectious diseases
Cytomegalovirus (CMV) Infection
Prevention of Cytomegalovirus
Prophylaxis or preemptive treatment (actively monitoring patients by viral load and giving antivirals to those with evidence of infection) is effective for preventing CMV disease in solid organ or hematopoietic cell transplant recipients infected with CMV and at risk of CMV disease. Medications used includeganciclovir,valganciclovir, andfoscarnet.Letermoviris a newer agent with a novel mechanism of action that can be used for prophylaxis in bone marrow or renal transplantation. It has many important drug interactions, including withcyclosporine,tacrolimus,sirolimus, andvoriconazole. 