pediatrics
Congenital and Perinatal Cytomegalovirus Infection (CMV)
Treatment of Congenital and Perinatal CMV Infection
Ganciclovirorvalganciclovirfor symptomatic neonates 16 mg/kg 2 times a day for 6 months decreases viral shedding in neonates with congenital CMV and modestly improves hearing and developmental outcomes at 12 and 24 months of age ( Treatment reference ). In utero treatment of affected fetuses with The main toxicity of treatment is Neutropenia . 1.Kimberlin DW, Jester PM, Sánchez PJ, et al:Valganciclovirfor symptomatic congenital cytomegalovirus disease.N Engl J Med372(10):933–943, 2015. doi: 10.1056/NEJMoa1404599 