mouth and dental disorders
Complications After Dental Treatment
Osteonecrosis of the jaw
 Medication-Related Osteonecrosis of the Jaw (MRONJ) is a disorder that involves bone death of areas of the jawbones after exposure of the jawbone through the gum tissue. The disorder usually causes pain, loosening of teeth, and a discharge of pus. The disorder may occur after Tooth extraction An injury Radiation therapy to the head and neck (osteoradionecrosis) Use of bisphosphonate drugs in high doses or for long periods , and zoledronate. Bisphosphonates seem to have a higher risk of causing osteonecrosis of the jaw in people who undergo oral surgery of the lower jaw while taking intravenous bisphosphonates, those who have previously been given high doses of bisphosphonates by vein (common with certain cancer treatments), or those who have been taking bisphosphonates for a long period of time. The risk of developing osteonecrosis of the jaw is much lower (about 1 in 1,000) in people who are given bisphosphonates in standard doses for Osteoporosis for shorter periods of time. Treatment typically involves scraping away some of the damaged bone (debridement), taking antibiotics by mouth, and using antibacterial mouth rinses. 