children s health issues
Trisomy 18
Symptoms of Trisomy 18
In the womb, affected fetuses are not typically very active, and there is often excess amniotic fluid, a small placenta, and restricted growth. At birth, newborns often have a low birth weight and their muscles and body fat are underdeveloped. Newborns are typically limp and have a weak cry. The mouth and jaw may be small, which gives the newborn's face a pinched appearance. The hands are clenched in fists, and the index fingers often overlap the middle and ring fingers. The fingernails are underdeveloped. Skinfolds, especially over the back of the neck, are common. The big toes are shortened and frequently bend upward. Clubfoot and Other Foot Defects and rocker-bottom feet are common. Other visible deformities are common, including a small head, low-set and malformed ears, a narrow pelvis, and a short breastbone (sternum). Physical abnormalities may be obvious at birth. However, some newborns have abnormalities that are not as obvious. Image courtesy of the Centers for Disease Control and Prevention Public Health Image Library. Image courtesy of the Centers for Disease Control and Prevention Public Health Image Library. Image courtesy of the Centers for Disease Control and Prevention Public Health Image Library. Internal organs also have defects. Severe abnormalities may be present in the heart, lungs, digestive tract, and kidneys. Newborns may also have Abdominal Wall Hernias , muscles that have separated from the abdominal wall, or both. Boys may have 