eye disorders
Uveitis Caused by Connective Tissue Disease
Tubulointerstitial nephritis and uveitis syndrome (TINU)
TINU typically presents with nongranulomatous acute bilateral anterior uveitis, though it is frequently accompanied by posterior complications, including edema of the optic nerve and macula. It most commonly affects adolescent females but can present at any age. Symptoms include eye pain and redness, decreased visual acuity, and photophobia. Patients may have a history of viral prodrome symptoms and also flank pain, polyuria, and nocturia. Evaluation for Tubulointerstitial Nephritis may include urine beta-2 microglobulin levels and sometimes Treatment with oral steroids in the acute phase and use of noncorticosteroid immunosuppressive drugs (eg,mycophenolatemofetil) for chronic disease is often necessary. 