special subjects
Valerian
Drug Interactions
 to inhibit both CYP3A4 metabolism and p-glycoprotein activity ( References ), but no clinical studies have shown any drug metabolism interactions. Valerianmay prolong the effect of other sedatives (eg, barbiturates) and affect driving or other activities requiring alertness.Valerianshould not be taken along with alcohol or sedatives. (See also table.) 