gastrointestinal disorders
Polyps of the Colon and Rectum
Prevention of Colorectal Polyps
 and COX-2 inhibitors may help prevent formation of new polyps in patients with polyps or colon cancer ( Prevention reference ). The potential benefits of long-term therapy with these agents must be weighed against the potential adverse effects (eg, bleeding, renal dysfunction). 1.Cook NR, Lee IM, Zhang SM, et al: Alternate-day, low-doseaspirinand cancer risk: Long-term observational follow-up of a randomized trial.Ann Int Med159:77–85, 2013. doi: 10.7326/0003-4819-159-2-201307160-00002 