dermatologic disorders
Erythema Multiforme
Treatment of Erythema Multiforme
Supportive care Sometimes prophylactic antivirals Erythema multiforme spontaneously resolves, so treatment is usually unnecessary. Topical corticosteroids and anesthetics and oral antihistamines may ameliorate symptoms and reassure patients. Recurrences are common, and empiric oral maintenance therapy with antiherpetic drugs such asacyclovir400 mg orally every 12 hours,famciclovir250 mg orally every 12 hours, orvalacyclovir1000 mg orally every 24 hours can be attempted if symptoms recur more than 5 times/year and HSV association is suspected or if recurrent erythema multiforme is consistently preceded by herpes flares. 