neurologic disorders
Overview of Peripheral Nervous System Disorders
Etiology
Peripheral nerve disorders can result from damage to or dysfunction of the one of the following: Cell body Myelin sheath Axons Neuromuscular junction Disorders can be genetic or acquired (due to toxic, metabolic, traumatic, infectious, or inflammatory conditions—see table Some Causes of Peripheral Nervous System Disorders ). Peripheral neuropathies may affect One nerve ( Mononeuropathies ) Several discrete nerves ( Multiple Mononeuropathy , or mononeuritis multiplex) Multiple nerves diffusely ( Polyneuropathy ) A plexus ( Brachial Plexus and Lumbosacral Plexus Disorders ) A nerve root ( Nerve Root Disorders ) More than one site can be affected; eg, in the most common variant of Guillain-Barré Syndrome (GBS) , multiple segments of cranial nerves, usually the 2 facial nerves, may be affected. 