dermatologic disorders
Necrotizing Soft Tissue Infection
Key Points
Necrotizing soft-tissue infection (NSTI) can develop from a contiguous ulcer or infection, hematogenous spread, or after trauma. Consider NSTI in patients with characteristic findings or pain out of proportion to clinical findings, particularly patients with diabetes or other risk factors. Arrange surgical therapy while instituting IV fluid and antibiotic therapy and without delaying for testing. 