gynecology and obstetrics
Hyperemesis Gravidarum
Key Points
Hyperemesis gravidarum is severe nausea and vomiting during pregnancy that, unlike morning sickness, can cause weight loss, ketosis, dehydration, and sometimes electrolyte abnormalities. Exclude other disorders that can cause vomiting based on the woman's symptoms. Determine severity by measuring serum electrolytes, urine ketones, BUN, creatinine, and body weight. Suspend oral intake at first, give fluids and nutrients IV, restore oral intake gradually, and give antiemetics as needed. 