endocrine and metabolic disorders
Cushing Syndrome
Introduction
Cushing syndromeis a constellation of clinical abnormalities caused by chronic high blood levels of cortisol or related corticosteroids.Cushing diseaseis Cushing syndrome that results from excess pituitary production of adrenocorticotropic hormone (ACTH), generally secondary to a pituitary adenoma. Typical symptoms and signs include moon face and truncal obesity, easy bruising, and thin arms and legs. Diagnosis is by history of receiving corticosteroids or by finding elevated and/or relatively autonomous serum cortisol. Treatment depends on the cause. (See also Overview of Adrenal Function .) 