kidney and urinary tract disorders
Polycystic Kidney Disease (PKD)
Introduction
Polycystic kidney disease is a hereditary disorder in which many fluid-filled sacs (cysts) form in both kidneys. The kidneys grow larger but have less functioning tissue. Polycystic kidney disease is caused by an inherited gene defect. Some people have such mild symptoms that they do not realize they have a disorder, but others have pain in the side, Blood in Urine , Diagnosis is based on Ultrasonography , The kidney stones and infections are treated, but more than half of affected people eventually need or There are several genetic defects that cause polycystic kidney disease (PKD). Several types are caused by dominant genes, and one rare type is caused by a recessive gene. That is, a person with the disease has inherited either one copy of a dominant gene from one parent or two copies of a recessive gene, one from each parent. People with dominant gene inheritance usually have no symptoms until adulthood. People with recessive gene inheritance develop severe illness in childhood. In polycystic kidney disease, many cysts form in both kidneys. The cysts gradually enlarge, destroying some or most of the normal tissue in the kidneys. The genetic defect leads to the widespread formation of cysts in the kidneys. Gradual enlargement of the cysts with increasing age is accompanied by a reduction of blood flow and scarring within the kidneys. Cysts may become infected or bleed. Stones in the Urinary Tract may develop. 