immune disorders
Angioedema
Chronic angioedema
Angioedema can be chronic, recurring over weeks or months. The cause is usually unknown, but it may be repeated, unintentional intake of a substance, such as penicillin in milk or a preservative or dye in foods. Use of certain drugs, such asaspirin, other NSAIDs, or opioids, can also cause chronic angioedema. Chronic angioedema that occurs without hives may be hereditary or acquired angioedema. However, usually when angioedema without hives recurs, no specific cause is identified—called idiopathic angioedema. 