pediatrics
Congenital Limb Abnormalities
Syndactyly
Syndactyly is webbing or fusion of fingers or toes. Several different types are defined, and the majority follow an autosomal dominant inheritance pattern. Simple syndactyly involves only fusion of the soft tissue, whereas complex syndactyly also involves fusion of the bones. Complex syndactyly is present in Apert syndrome (with Craniosynostosis ). Syndactyly of the ring and the small fingers is common in oculo-dento-digital dysplasia. Smith-Lemli-Opitz syndrome manifests with syndactyly of the second and third toes along with multiple other congenital anomalies. 