hematology and oncology
Von Willebrand Disease
Symptoms and Signs of Von Willebrand Disease
Bleeding manifestations in the most common type I von Willebrand disease (VWD) include bruising, mucosal bleeding, bleeding from small skin cuts that may stop and start over hours, increased menstrual bleeding, and sometimes bleeding after surgical procedures (eg, tooth extraction, tonsillectomy). Platelets function well enough that petechiae and purpura rarely occur. Patients with type III VWD may additionally experience spontaneous major bleeding under the skin (hematomas) and are at particular risk of life-threatening bleeding with many minor and major surgical procedures. 