musculoskeletal and connective tissue disorders
Systemic Sclerosis
Classification of Systemic Sclerosis
Systemic sclerosis is classified as Limited systemic sclerosis (CREST syndrome) Generalized systemic sclerosis (with diffuse skin involvement) Systemic sclerosis sine scleroderma (CREST syndrome—calcinosis cutis, Raynaud Syndrome , patients have Raynaud syndrome and gastrointestinal (GI) complications. This type typically evolves rapidly. Overview of Interstitial Lung Disease and scleroderma renal crisis are the major complications. Insystemic sclerosis sine scleroderma,patients have systemic sclerosis–related antibodies and visceral manifestations of the disease but no skin tightening. 