critical care medicine
Drugs to Aid Intubation
Drugs to cause paralysis for intubation
Skeletal muscle relaxation with an IV neuromuscular blocker markedly facilitates intubation. 1 to 2 days old, spinal cord injury, neuromuscular disease, renal failure, or possibly penetrating eye injury. About 1/15,000 children (and fewer adults) have a genetic susceptibility to Malignant Hyperthermia due to Alternative nondepolarizing neuromuscular blockers have longer duration of action (>30 minutes) but also have slower onset unless used in high doses that prolong paralysis significantly. Drugs includeatracurium0.5 mg/kg, mivacurium 0.15 mg/kg,rocuronium1.0 mg/kg, andvecuronium0.1 to 0.2 mg/kg injected over 60 seconds. 