women s health issues
Molar Pregnancy
Types of gestational trophoblastic disease
Gestational trophoblastic disease is a group of disorders that develop from cells (called trophoblasts) that surround a Development of the Embryo and that eventually form the placenta and amniotic sac. The affected cells grow abnormally and multiply quickly. Gestational trophoblastic disease includes Noncancerous tumors that may become cancerous: These tumors include hydatidiform mole, exaggerated placental site, and placental site nodule. Cancerous tumors located in the placenta: These tumors (called gestational trophoblastic neoplasia) include placental-site trophoblastic tumor, epithelioid trophoblastic tumor, choriocarcinoma, and invasive mole. Approximately 80% of cases of gestational trophoblastic disease are not cancerous. The rest tend to persist and start to invade surrounding tissue. Approximately 2 to 3% of hydatidiform moles develop into choriocarcinomas. Choriocarcinomas can spread quickly through the lymphatic vessels or bloodstream. Placental-site trophoblastic tumors and epithelioid trophoblastic tumors are very rare. 