infectious diseases
Tetracyclines
Dosing Considerations for Tetracyclines
Doxycycline,eravacycline, andomadacyclineare excreted primarily in the intestinal tract and require no dose reduction in renal insufficiency, whereastetracyclineandminocyclinerequire dose adjustment in patients with reduced kidney function. Tetracyclines may decrease the effectiveness of oral contraceptives and potentiate the effects of oral anticoagulants. 