infectious diseases
Vancomycin
Pharmacokinetics
Vancomycinis not appreciably absorbed from a normal gastrointestinal tract after oral administration. Given parenterally, it penetrates into bile and pleural, pericardial, synovial, and ascitic fluids. However, penetration into even inflamed cerebrospinal fluid is low and erratic. Vancomycinis excreted unchanged by glomerular filtration. 