hematology and oncology
Eosinophilia
Treatment of Eosinophilia
Sometimes corticosteroids Corticosteroid treatment of hypereosinophilic syndrome is discussed elsewhere (see Immediate therapy ).. ( Treatment references ). If no cause is detected, the patient is followed for complications. A brief trial with low-dose corticosteroids may lower the eosinophil count if eosinophilia is secondary (eg, to allergy, systemic rheumatic disease, or parasitic infection) rather than primary. Such a trial is indicated if eosinophilia is persistent and progressive in the absence of a treatable cause. Because eosinophilia can involve multiple organ systems or may be a manifestation of a systemic disorder, multiple specialists may be needed for diagnostic and therapeutic input ( Treatment references ). 1.Pelaia C, Calabrese C, Vatrell A, et al:Benralizumab: from the basic mechanism of action to the potential use in the biological therapy of severe eosinophilic asthma.Biomed Res Int2018;2018:4839230. doi:10.1155/2018/4839230 2.Eldaabossi SAM, Awad A, Anshasi N:Meprolizumabanddupliumabas a replacement to systemic glucocorticoids for the treatment of chronic eosinophilic pneumonia and allergic bronchopulmonary aspergillus-Case series, Almoosa specialist hospital.Respir Med Case Rep34:201520, 2021. doi: 10.1016/j.rmcr.2021.101520 3.Thomsen GN, Christoffersen MN, Lindegaard HM, et al: The multidisciplinary approach to eosinophilia.Front Oncol13:1193730, 2023. doi:10.3389/fonc.2023.1193730 