digestive disorders
Whipple Disease
Treatment of Whipple Disease
Antibiotics If left untreated, Whipple disease becomes progressively worse and is fatal. Whipple disease can be cured with antibiotics. Usually people are givenceftriaxoneor penicillin initially by vein for 2 to 4 weeks, followed bytrimethoprim/sulfamethoxazole or a combination ofdoxycyclineandhydroxychloroquinetaken by mouth for at least 12 months. Symptoms subside rapidly. Despite an initial response to antibiotics, however, the disease can come back. 