dermatologic disorders
Candidiasis (Mucocutaneous)
Treatment of Mucocutaneous Candidiasis
Sometimes drying agents Topical or oral antifungals Intertriginous infectionis treated with drying agents as needed (eg, Burow solution compresses applied for 15 to 20 minutes for oozing lesions) and topical antifungals (see table). Powdered formulations are also helpful (eg,miconazolepowder 2 times a day for 2 to 3 weeks).Fluconazole150 mg orally once a week for 2 to 4 weeks can be used for extensive intertriginous candidiasis; topical antifungals may be used at the same time. Candidal diaper rashis treated with more frequent changes of diapers, use of super- or ultra-absorbent disposable diapers, and an imidazole cream 2 times a day. Oralnystatinis an option for infants with coexisting oropharyngeal candidiasis. Candidal paronychiais treated by protecting the area from wetness and giving topical or oral antifungals. These infections are often resistant to treatment. Thymol 4% in alcohol applied to the affected area 2 times a day is often helpful. Oral candidiasiscan be treated by dissolving 1clotrimazole10-mg troche in the mouth 4 to 5 times a day for 14 days. Another option isnystatinoral suspension. A systemic antifungal may also be used (eg, oralfluconazole). Chronic mucocutaneous candidiasisrequires long-term oral antifungal treatment with oralfluconazole. 