children s health issues
Trisomy X
Introduction
Trisomy X is a common Overview of Sex Chromosome Abnormalities in which girls are born with three X chromosomes (XXX). Chromosomes are structures within cells that contain The Sex chromosomes determine whether a fetus becomes male or female. A pair of X and Y chromosomes (XY) results in a male, and a pair of X and X chromosomes (XX) results in a female. In trisomy X, the extra X chromosome is usually inherited from the mother. The older the mother is, the greater the chance her fetus could have the syndrome. About 1 in every 1,000 girls is born with the third X chromosome. Trisomy X rarely causes obvious physical abnormalities. Girls with trisomy X may have slightly lower intelligence, problems with verbal skills, and more school problems than siblings. Sometimes the syndrome causes menstrual irregularities and infertility. However, some women with trisomy X have given birth to physically normal children who have normal chromosomes. Extremely rare cases of infants with four or even five X chromosomes have been identified. The more X chromosomes the girl has, the greater the chance of Intellectual Disability and physical abnormalities. 