pediatrics
Congenital Toxoplasmosis
Prognosis for Congenital Toxoplasmosis
Some children have a fulminant course with early death, whereas others have long-term neurologic sequelae. Occasionally, neurologic manifestations (eg, chorioretinitis, intellectual disability, deafness, seizures) develop years later in children who appeared normal at birth. Consequently, children with congenital toxoplasmosis should be closely monitored beyond the neonatal period. The severity of infection may correlate with parasite burden in amniotic fluid measured by PCR testing ( Prognosis reference ). 1.Yamamoto L, Targa LS, Sumita LM, et al: Association of parasite load levels in amniotic fluid with clinical outcome in congenital toxoplasmosis.Obstet Gynecol130(2):335–345, 2017. doi: 10.1097/AOG.0000000000002131 