psychiatric disorders
Antisocial Personality Disorder (ASPD)
Etiology of Antisocial Personality Disorder
Both genetic and environmental factors (eg, Overview of Child Maltreatment ) contribute to the development of antisocial personality disorder. A possible mechanism is impulsive rather than planned aggression, related to abnormal serotonin transporter functioning. Disregard for the pain of others during early childhood has been linked to antisocial behavior during late adolescence. Antisocial personality disorder is more common among 1st-degree relatives of patients with the disorder than among the general population ( Etiology references ). Risk of developing this disorder is increased in both adopted and biologic children of parents with the disorder. If Conduct Disorder accompanied by 1.Polderman TJC, Benyamin B, de Leeuw CA, et al: Meta-analysis of the heritability of human traits based on fifty years of twin studies.Nat Genet47(7):702-709, 2015. doi: 10.1038/ng.3285 2.Storebø OJ, Simonsen EJ: The association between ADHD and antisocial personality disorder (ASPD): A review.Atten Disord: 20(10):815-24, 2016. doi: 10.1177/1087054713512150 3.Reti IM, Samuels JF, Eaton WW, et al: Adult antisocial personality traits are associated with experiences of low parental care and maternal overprotection.Acta Psychiatr Scand106(2):126-133, 2002. doi: 10.1034/j.1600-0447.2002.02305.x 