infections
Sepsis and Septic Shock
Causes of Sepsis and Septic Shock
Sepsis occurs when toxins produced by certain bacteria cause cells in the body to release substances that trigger inflammation ( Innate Immunity ). Although cytokines help the immune system fight infection, they can have harmful effects: They can cause the blood vessels to widen (dilate), decreasing blood pressure. They can cause blood to clot in tiny blood vessels inside organs. , cause sepsis. Infections that can lead to sepsis begin most commonly in the lungs, abdomen, or urinary tract. In most people, these infections do not lead to sepsis. However, sometimes bacteria spread into the bloodstream (a condition called Bacteremia ). Sepsis may then develop. If the initial infection involves an abscess, the risk of bacteremia and sepsis is increased. Occasionally, such as in 