dermatologic disorders
Atypical Moles
Introduction
Atypical moles are benign melanocytic nevi with irregular and ill-defined borders, variegated colors usually of brown and tan tones, and macular or papular components. Patients with atypical moles have an increased risk of Melanoma . Management is by close clinical monitoring and biopsy of highly atypical or changed lesions. Patients should reduce sun exposure and conduct regular self-examinations for new moles or changes in existing ones. Atypical moles are nevi with a slightly different clinical and histologic appearance (disordered architecture and atypia of melanocytes). Some patients have only one or a few atypical moles; others have many. Although most melanomas arise de novo, some develop from atypical moles ( General references ). Risk factors for melanoma include increased number of atypical moles and increased exposure to ultraviolet radiation and sun. This image shows an atypical nevus, with the characteristic irregular border and variable coloration. Image courtesy of Marie Schreiner, PA-C. This image shows atypical nevi, with characteristic irregular borders and variable coloration. Image courtesy of Marie Schreiner, PA-C. This photo shows a rounded mole with irregular borders. DR P. MARAZZI/SCIENCE PHOTO LIBRARY 2 first-degree relatives. These patients are at markedly increased risk of melanoma ( General references ). 