lung and airway disorders
Beryllium Disease
Diagnosis of Beryllium Disease
A history of exposure to beryllium Chest imaging (x-ray or computed tomography) Test for sensitization to beryllium A chest x-ray may be normal or show abnormalities, often resembling those seen in people with sarcoidosis. Computed Tomography (CT) of the Chest is more sensitive than x-ray, although people with beryllium disease can have normal imaging test results. Pulmonary Function Testing (PFT) results vary and can show restriction, reduced diffusing capacity for carbon monoxide (DLCO), and/or obstruction in people with beryllium disease. A test called the BeLPT, in which lymphocytes (a type of White Blood Cells ), obtained from a blood sample or from fluid obtained through The diagnosis of beryllium disease can be challenging. However, doctors can make a diagnosis of probable beryllium disease based on various combinations of diagnostic criteria, including a history of exposure, chest imaging, abnormal pulmonary function test results, abnormal BeLPT results,, and lung biopsy. Certain findings, such as an abnormal BeLPT, provide greater diagnostic certainty than others, such as nonspecific x-ray changes. 