nutritional disorders
Riboflavin Deficiency
Symptoms and Signs ofRiboflavinDeficiency
The most common signs ofriboflavindeficiency are pallor and maceration of the mucosa at the angles of the mouth (angular stomatitis) and vermilion surfaces of the lips (cheilosis), eventually replaced by superficial linear fissures. The fissures can become infected withCandida albicans, causing grayish white lesions (perlèche). The tongue may appear magenta. Seborrheic dermatitis develops, usually affecting the nasolabial folds, ears, eyelids, and scrotum or labia majora. These areas become red, scaly, and greasy. Rarely, neovascularization and keratitis of the cornea occur, causing lacrimation and photophobia. 