infectious diseases
Marburg and Ebola Virus Infections
Key Points
Ebola and Marburg viruses, although distinct, cause similar hemorrhagic fevers; outbreaks are perpetuated mainly by human-to-human transmission via contact with infected body fluids, organs of infected people, or cadavers. Suspect Marburg or Ebola virus infection in patients with bleeding tendencies, fever, other compatible symptoms, and travel from endemic areas. Isolate patients with possible infection in dedicated containment facilities, and use strict procedures to protect workers who care for these patients. Ebola vaccines are being developed for Zaire ebolavirus, and 2 are currently in routine use in the DRC. Three candidate vaccines have been developed for Sudan ebolavirus. Plan diagnosis, management, and prevention of transmission with public health authorities. 