pediatrics
BRUE
Differential diagnosis
BRUE is diagnosed only when there is no explanation for the event. A number of disorders can manifest with similar abnormalities of breathing, responsiveness, tone, and/or skin color. Thus, it is important to search for a cause. Themost common possible causesinclude Digestive: Gastroesophageal Reflux Disease (GERD) or Neurologic: Neurologic disorders (eg, Seizure Disorders , Respiratory: Infections (eg, Respiratory Syncytial Virus (RSV) and Human Metapneumovirus Infections , Infectious: Sepsis and Septic Shock , Less common possible causesinclude Cardiac disorders Metabolic disorders Upper airway obstruction (eg, Obstructive Sleep Apnea (OSA) ) Other (eg, drug-related, anaphylaxis, Overview of Child Maltreatment ) Causes may be genetic or acquired. If an infant is under the care of one person and has repeated episodes with no clear etiology, child abuse should be considered. 