children s health issues
Cholesteryl Ester Storage Disease and Wolman Disease
Wolman disease
Wolman disease is the more severe disease. This disease occurs in the first few weeks of life. Infants feed poorly, vomit, and have an enlarged spleen and liver. Calcium deposits in the adrenal glands cause them to harden. Bowel movements contain excess fat, which results in oily, unusually foul-smelling, bulky stools (steatorrhea). Infants with Wolman disease usually die by 6 months of age if untreated. 