brain, spinal cord, and nerve disorders
Stiff Person Syndrome
Treatment of Stiff Person Syndrome
Diazepam(a sedative) or another drug to relax the muscles Immune globulin Sometimes corticosteroids Sometimesrituximabor plasma exchange Treatment of stiff-person syndrome focuses on relieving symptoms. The sedativediazepamcan consistently relieve the muscle stiffness. Ifdiazepamis ineffective, other drugs, such asbaclofen(a muscle relaxant), may be tried. Immune globulin (a solution containing many different antibodies collected from a group of donors), given by vein (intravenously), may help relieve symptoms for up to a year. Corticosteroids can help but, if taken for a long time, have many side effects. (a drug that modifies the immune system's activity) or Plateletpheresis (platelet donation) , which involves filtering toxic substances (including the abnormal antibodies) from the blood, is sometimes tried. 