pediatrics
Reye Syndrome
Treatment of Reye Syndrome
Support measures, including measures to lower increased intracranial pressure Usually treatment of coagulopathy Treatment of Reye syndrome is supportive, with particular attention paid to control of increased intracranial pressure and blood glucose because glycogen depletion is common. Treatment of elevated increased intracranial pressure includes intubation, hyperventilation, fluid restriction of 1500 mL/m2/day, elevating the head of the bed, osmotic diuretics, direct increased intracranial pressure monitoring, and decompressing craniotomy. Infusion of 10 or 15%dextroseis common to maintain euglycemia. Coagulopathy may require fresh frozen plasma or vitamin K. Other treatments (eg, exchange transfusion, hemodialysis, barbiturate-induced deep coma) have not been proved effective but are sometimes used. 