liver and gallbladder disorders
Sinusoidal Obstruction Syndrome of the Liver
Causes of Sinusoidal Obstruction Syndrome
Common causes include the following: Ingestion of pyrrolizidine alkaloids, which are found in crotalaria and senecio plants (used in Jamaica to make herbal tea) and in other herbs, such as comfrey (see Medicinal herbs and the liver ) Use of certain drugs that occasionally have toxic effects on the liver, includingcyclophosphamideandazathioprine(used to suppress the immune system) Radiation therapy (used to suppress the immune system before bone marrow or Stem Cell Transplantation ) A reaction after bone marrow or stem cell transplantation (graft-versus-host disease) In Graft-versus-host disease , white blood cells in the transplanted tissue attack the recipient’s tissues. This reaction tends to occur about 3 weeks after transplantation. 