infectious diseases
Escherichia coli Infections
Treatment of E. coli Infections
E. coli have also acquired resistance genes that encode AmpC beta-lactamases, serine carbapenemases, and metallo-carbapenemases. The tetracycline–like agents (eg, tigecycline, eravacycline) and cefiderocol (an injectable siderophore cephalosporin) are also active against ESBL-producing strains as well as AmpC beta-lactamase–, serine carbapenemase–, and metallo-carbapenemase–producing strains. Fosfomycin has activity against multidrug-resistant strains and is an oral alternative for lower UTIs.