immunology allergic disorders
Chronic Mucocutaneous Candidiasis
Treatment of Chronic Mucocutaneous Candidiasis
Antifungal drugs Treatment of endocrine and autoimmune manifestations Usually, the infections of chronic mucocutaneous candidiasis can be controlled with a topical antifungal, If patients have a poor response to topical antifungals, long-term treatment with a systemic antifungal drug (eg,amphotericin B,fluconazole,ketoconazole) may be needed. Immune globulin should be considered if patients have antibody deficiency. Autoimmune (including endocrine) manifestations are treated aggressively. Hematopoietic Stem Cell Transplantation has rarely been successful and could be considered as last-line treatment in severe cases. 