hematology and oncology
Hemolytic Uremic Syndrome (HUS)
Etiology of HUS
Most cases occur in children and follow Acute infection toxin–producing bacteria (eg, Infection by Escherichia coli O157:H7 and Other Enterohemorrhagic E. coli (EHEC) , or some strains of A small minority of cases are unrelated to infection and involve Dysregulation of the complement system Complement dysregulation is usually from a mutation in genes controlling complement proteins or factors but sometimes from acquired autoantibodies to certain complement factors. Congenital complement disorders may also increase the risk of hemolytic-uremic sydrome (HUS) following infection. 