pediatrics
Perinatal Physiology
Neonatal Renal Function
At birth, renal function is generally reduced, particularly in preterm infants. Glomerular filtration rate (GFR) increases progressively during gestation, particularly during the third trimester. GFR rapidly increases in the first months of life; however, GFR,ureaclearance, and maximum tubular clearances do not reach adult levels until age 1 to 2 years. 