special subjects
Cannabinoids, Synthetic
Introduction
Synthetic cannabinoids are manufactured drugs that are tetrahydrocannabinol (THC) receptor agonists. They are typically applied to dried plant material and smoked. THC is the primary active ingredient in Marijuana (Cannabis) (cannabis). There are many chemical families of synthetic cannabinoids, including HU-210, JWH-073, JWH-018, JWH-200, AM-2201, UR-144, and XLR-11; new compounds are being reported regularly. Slang terms for these include "K2" and "spice." Effects vary greatly depending on the specific cannabinoid, and many of the acute and chronic effects remain unknown. However, stimulation of the THC receptor causes altered mental status with agitation, hallucinations, and psychosis (that may be irreversible). Cardiovascular effects include hypertension, tachycardia, and Overview of Acute Coronary Syndromes (ACS) . Neurologic effects include seizures and blurred vision. Additional reported effects include vomiting, hyperthermia, rhabdomyolysis, and renal failure. 