hematology and oncology
Acquired Platelet Dysfunction
Systemic disorders
Many disorders (eg, Overview of Myeloproliferative Neoplasms , Uremia prolongs bleeding via unknown mechanisms. If bleeding is observed clinically in uremic patients, bleeding may be reduced with vigorous dialysis, cryoprecipitate administration, ordesmopressininfusion. If necessary, increasing the hemoglobin concentration to > 10 g/dL (>100 g/L) by transfusion or by giving erythropoietin also reduces bleeding. 