endocrine and metabolic disorders
ArginineVasopressin Deficiency (Central Diabetes Insipidus)
Etiology ofArginineVasopressinDeficiency
Genetic abnormalities of thevasopressingene on chromosome 20 are responsible for autosomal dominant forms of primaryargininevasopressindeficiency, but many cases are idiopathic. deficiency may also be secondary (acquired), caused by various lesions, including hypophysectomy, cranial injuries (particularly basal skull fractures), suprasellar and intrasellar tumors (primary or metastatic), Langerhans Cell Histiocytosis , lymphocytic hypophysitis, granulomas ( 