hormonal and metabolic disorders
Polyglandular Deficiency Syndromes
Symptoms of Polyglandular Deficiency Syndromes
In people with polyglandular deficiency syndromes, symptoms depend on which endocrine organs are affected. Adrenal Insufficiency : Weakness, loss of appetite, vomiting, dark skin patches, and, in severe cases, low blood pressure and death if not treated Hypothyroidism : Weight gain, constipation, dry hair and skin, and sometimes inability to tolerate cold weather Hypoparathyroidism : Tingling around the mouth, cramping of hands and feet, and seizures 