infectious diseases
Chloramphenicol
Use During Pregnancy and Breastfeeding
Use ofchloramphenicolduring pregnancy results in fetal drug levels almost as high as maternal levels. Use has been associated with gray baby syndrome in newborns but no teratogenic effects. It may be used in pregnancy to treat Rocky Mountain spotted fever if a 2nd-line agent is required, but caution is warranted in the 3rd trimester. Chloramphenicolenters breast milk. It should not be used during breastfeeding; serious adverse reactions are possible, particularly in young or low weight infants. 