cardiovascular disorders
Drugs for Acute Coronary Syndromes
Nitrates
A short-acting nitrate,nitroglycerin, is used to reduce cardiac workload in selected patients.Nitroglycerindilates veins, arteries, and arterioles, reducing left ventricular preload and afterload. As a result, myocardial oxygen demand is reduced, lessening ischemia. is recommended during the first 24 to 48 hours for patients with Heart Failure (HF) , large anterior myocardial infarction, persistent chest discomfort, or Longer use may benefit patients with recurrent chest pain or persistent pulmonary congestion. In high-risk patients,nitroglyceringiven in the first few hours reduces infarct size and short-term and possibly long-term mortality risk.Nitroglycerinis not routinely given to low-risk patients with uncomplicated myocardial infarction. 