gynecology and obstetrics
Decreased Ovarian Reserve (DOR)
Diagnosis of Decreased Ovarian Reserve
Follicle-stimulating hormone (FSH) andestradiollevels for screening Antimüllerian hormone (AMH) level and/or antral follicle count (AFC) (See alsoTesting and interpreting measures of ovarian reserve: A committee opinion, from the Practice Committee of the American Society for Reproductive Medicine and the American Society for Reproductive Medicine.) Testing for decreased ovarian reserve is considered for women who Are ≥ 35 Have had ovarian surgery Have responded poorly to treatments such as ovarian stimulation with exogenous gonadotropins levels ≥ 80 pg/mL on day 3 of the Menstrual Cycle suggest ovarian reserve is decreased. However, the AMH level and AFC are currently the best tests for diagnosing decreased ovarian reserve. is an early, reliable predictor of declining ovarian function. A low AMH level (< 1.0 ng/mL) predicts a lower chance of pregnancy after In vitro fertilization (IVF) (IVF); pregnancy is rare when the level is too low to be detected. TheAFCis the total number of follicles that measure 2 to 10 mm (mean diameter) in both ovaries during the early follicular phase; AFC is determined by observation during transvaginal ultrasonography. If AFC is low (3 to 10), pregnancy after IVF is less likely. 