hematology and oncology
Hypereosinophilic Syndrome
Symptoms and Signs of Hypereosinophilic Syndrome
Symptoms are diverse and depend on which organs are dysfunctional (see table). Occasionally, patients with very severe eosinophilia (eg, eosinophil counts of>100,000/mcL [> 100 × 109/L]) develop complications of hyperleukocytosis, such as manifestations of brain or lung hypoxia (eg, encephalopathy, dyspnea, respiratory failure). Other thrombotic manifestations (eg, cardiac mural thrombi) may also occur. 