endocrine and metabolic disorders
Syndrome of Inappropriate ADH Secretion (SIADH)
Symptoms and Signs of SIADH
Symptoms of SIADH are those of hyponatremia, which mainly involve central nervous system dysfunction and generally occur when the effective plasma osmolality falls to<240 mOsm/kg (< 240 mmol/kg). Symptoms can be subtle and consist mainly of changes in mental status, including altered personality, lethargy, and confusion. As the serum sodium falls to<115 mEq/L (< 115 mmol/L), stupor, neuromuscular hyperexcitability, hyperreflexia, seizures, coma, and death can result. 