dermatologic disorders
Epidermolysis Bullosa
Treatment of Epidermolysis Bullosa
Avoidance of friction and trauma to skin and mucous membranes Treatment to promote healing of blister sites Prevention and treatment of complications (See also Wound International's2017 best practice guidelines for skin and wound care in epidermolysis bullosa.) Treatment of epidermolysis bullosa is symptomatic; multidisciplinary specialization may likely be needed for both severe and chronic disease ( Treatment reference ). Any and all means of reducing skin friction are used. Neonates and infants are handled with exquisite gentleness. Soft clothing, padded furniture, and cool ambient temperatures help reduce blister formation. A soft diet and stool softeners may be helpful if the gastrointestinal tract is affected. Bullae should be properly incised and dressed, as instructed by a wound care specialist, to prevent further skin damage and infection. Minimally adherent dressings and tapes may be used; often, bandages covered with petroleum jelly are held in place with a light gauze wrap. Drugs are given as needed for pain, itching, and infection. Surgical treatment may include gastrostomy tube placement, esophageal dilation, and correction of pseudosyndactyly and contractures. 1.El Hachem M, Zambruno G, Bourdon-Lanoy E, et al: Multicentre consensus recommendations for skin care in inherited epidermolysis bullosa.Orphanet J Rare Dis9:76, 2014. doi: 10.1186/1750-1172-9-76 