hematology and oncology
Secondary Iron Overload
Introduction
Secondary iron overload results from excess absorption of iron, repeated blood transfusions, or excess oral intake, typically in patients with disorders of erythropoiesis. Consequences can include systemic symptoms, liver disorders, cardiomyopathy, diabetes, erectile dysfunction, and arthropathy. Diagnosis is by elevated serum ferritin, iron, and transferrin saturation levels. Treatment is usually by iron chelation. (See also Overview of Iron Overload .) 