cardiovascular disorders
Nonatheromatous Arteriosclerosis
Arteriolosclerosis
Arteriolosclerosis affects distal arteries in patients with Diabetes Mellitus (DM) or Hyaline arteriolosclerosisaffects small arteries and arterioles in patients with diabetes; typically, hyaline thickening occurs, the arteriolar wall degenerates, and the lumen narrows, causing diffuse ischemia, especially in the kidneys. occurs more often in patients with hypertension; typically, laminated, concentric thickening and luminal narrowing occur, sometimes with fibrinoid deposits and vessel wall necrosis (necrotizing arteriolitis). Hypertension promotes these changes, and arteriolosclerosis, by increasing arteriolar rigidity and increasing peripheral resistance, may help sustain the hypertension. 