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Neuroleptic Malignant Syndrome
Introduction
Neuroleptic malignant syndrome is characterized by altered mental status, muscle rigidity, hyperthermia, and autonomic hyperactivity that occur when certain neuroleptic drugs are used. Clinically, neuroleptic malignant syndrome resembles Malignant Hyperthermia . Diagnosis is clinical. Treatment is aggressive supportive care. Among patients taking neuroleptic drugs, about 0.02 to 3% develop neuroleptic malignant syndrome. Patients of all ages can be affected. (See also Overview of Heat Illness .) 