endocrine and metabolic disorders
Complications of Diabetes Mellitus
Other Complications of Diabetes Mellitus
Diabetic foot complications(skin changes, ulceration, infection, gangrene) are common and are attributable to vascular disease, neuropathy, and relative immunosuppression. These complications can lead to lower extremity amputations. are more common in patients with diabetes, including muscle infarction, Carpal Tunnel Syndrome , Patients with diabetes may also develop Ophthalmologic disease unrelated to Diabetic Retinopathy (eg, Hepatobiliary diseases (eg, Cirrhosis , Dermatologic disease (eg, Overview of Dermatophytoses , lower-extremity ulcers, diabetic dermopathy, necrobiosis lipoidica diabeticorum, diabetic systemic sclerosis, Depressive Disorders None Dementia None A patient with diabetes often develops microvascular disease, which may impair skin healing, so that even minor breaks in skin integrity can develop into deeper ulcers and easily become infected, particularly in the lower extremities. © Springer Science+Business Media Necrobiosis lipoidica is characteristic but not diagnostic of diabetes. Lesions most often appear on the legs and begin as erythematous papules that develop into atrophic, waxy, and yellow or brown lesions. Photo provided by Thomas Habif, MD. Acanthosis nigricans is skin thickening and pigmentation most typically developing in the axillae and nape of the neck (top); in people with dark skin, the skin may have a leathery appearance (bottom). It is most often a skin manifestation of impaired glucose tolerance, but it may reflect internal cancer, especially if onset is rapid and distribution is widespread. Photos provided by Thomas Habif, MD. This image shows erythematous bumps arranged in a ring or circular pattern on the torso of a patient with diabetes. SCIENCE PHOTO LIBRARY 