children s health issues
Mitochondrial Disorders
Leigh syndrome
Infants who have Leigh syndrome may have trouble feeding, poor head control, and delayed development. They may also have vomiting, irritability, continuous crying, and seizures that worsen during times of illness. This disorder begins in infants between the ages of 3 months and 2 years. Rarely, it occurs in adolescents and adults. As the disorder progresses, symptoms may also include generalized weakness, lack of muscle tone, and episodes of lactic acidosis, which can lead to breathing and kidney problems. There are no known treatments for Leigh syndrome. However, a very small number of children have a specific kind of Leigh syndrome that benefits from supplements of Thiamin Deficiency (vitamin B1). 