genitourinary disorders
Membranoproliferative Glomerulonephritis
Symptoms and Signs of Membranoproliferative Glomerulonephritis
Symptoms and signs are similar to those for other types of glomerulonephritis. The urine sediment may reveal hematuria (with dysmorphic red cells and/or red cell casts). The degree of proteinuria is variable. The serum creatinine may be normal or elevated. Patients with dense deposition disease, a subtype of complement-mediated MPGN, have a greater incidence of ocular abnormalities (basal laminar drusen, diffuse retinal pigment alterations, diskiform macular detachment, choroidal neovascularization), which ultimately impair vision. 