musculoskeletal and connective tissue disorders
Basic Calcium Phosphate Crystal Deposition Disease and Calcium Oxalate Crystal Deposition Disease
Calcium oxalate crystal deposition disease
Calcium oxalate crystal deposition is extremely rare. It occurs most often in azotemic patients receiving hemodialysis or peritoneal dialysis, particularly those treated withascorbic acid(vitamin C), which is metabolized to oxalate. However, the evolution of dialysis exchange fluids has resulted in the virtual disappearance of this disease. Crystals may deposit in blood vessel walls and skin, as well as joints. The Microscopic Examination of Crystals in Joints appear as positively or indeterminately birefringent bipyramidal structures. Synovial fluid may have > 2000 white blood cells/mcL. On x-ray, calcium oxalate crystals are indistinguishable from BCP periarticular calcifications or calcium pyrophosphate dihydrate (CPPD) crystal deposits in cartilage. Treatment of calcium oxalate crystal deposition disease is the same as that for Treatment . 