cardiovascular disorders
Infective Endocarditis
Prognosis for Infective Endocarditis
Overall, the in-hospital mortality rate for endocarditis is 15 to 20%, with a 1-year mortality rate approaching 40% ( Prognosis reference ). Untreated, infective endocarditis is always fatal. Even with treatment, death is more likely and the prognosis is generally poorer for older people and people who have Infection with resistant organisms An underlying disorder A long delay in treatment Aortic valve or multiple valve involvement Large vegetations Polymicrobial bacteremia Prosthetic valve infections Mycotic aneurysms Valve ring abscess Major embolic events Sepsis and Septic Shock is more likely in patients with diabetes, acute kidney injury, The prognosis is better with right-sided than left-sided endocarditis because tricuspid valve dysfunction is tolerated better, systemic emboli are absent, and right-sidedS. aureusendocarditis responds better to antimicrobial therapy. 1.Otto CM, Nishimura RA, Bonow RO, et al: 2020 ACC/AHA Guideline for the management of patients with valvular heart disease: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.J Am Coll Cardiol77(4):e25–e197, 2021. doi: 10.1016/j.jacc.2020.11.018 