pediatrics
Limb Girdle Dystrophy
Diagnosis of Limb Girdle Dystrophy
DNA mutation analysis Sometimes muscle biopsy Diagnosis of limb-girdle dystrophy is indicated by characteristic clinical findings, age at onset, and family history and requires mutation analysis of DNA from peripheral blood leukocytes as the primary confirmatory test. Muscle histology, immunocytochemistry, and Western blot analysis can be done. 