immunology allergic disorders
Hyper IgM Syndrome
Introduction
Hyper-IgM syndrome is an immunoglobulin (Ig) deficiency characterized by normal or elevated serum IgM levels and decreased levels or absence of other serum immunoglobulins, resulting in susceptibility to bacterial infections. (See also Overview of Immunodeficiency Disorders and Hyper-IgM syndrome is a Primary Immunodeficiencies that involves X-linked (most cases) Autosomal recessive Manifestations vary depending on the mutation and its location. 