infectious diseases
Adenovirus Infections
Diagnosis of Adenovirus Infections
Clinical evaluation For severe disease, polymerase chain reaction (PCR) testing of respiratory secretions and blood Laboratory diagnosis of adenovirus infection rarely affects management. During the acute illness, the virus can be isolated from respiratory and ocular secretions and frequently from stool and urine. A 4-fold rise in the serum antibody titer can indicate recent adenoviral infection but has little clinical utility. PCR testing can detect adenovirus DNA in respiratory secretions and blood and is useful when patients have severe disease and a diagnosis is needed. 