infectious diseases
Granuloma Inguinale
Symptoms and Signs of Granuloma Inguinale
Sites of infection are Penis, scrotum, groin, and thighs in men Vulva, vagina, and perineum in women Anus and buttocks in patients who engage in anal-receptive intercourse Face in both sexes After an incubation period of about 1 to 12 weeks, a painless, red skin nodule slowly enlarges, becoming a raised, beefy red, moist, smooth, foul-smelling lesion. The lesion slowly enlarges, often ulcerates, and may spread to other skin areas. Lesions heal slowly, with scarring. Secondary infections with other bacteria are common and can cause extensive tissue destruction. Lymphadenopathy is uncommon. Occasionally, granuloma inguinale spreads through the bloodstream to the bones, joints, or liver; without treatment, anemia, wasting, and, uncommonly, death may occur. This photo shows genital granuloma inguinale. Image courtesy of Joe Miller and Dr. Cornelio Arevalo via the Public Health Image Library of the Centers for Disease Control and Prevention. This photo shows genital granuloma inguinale. Image courtesy of Dr. Susan Lindsley via the Public Health Image Library of the Centers for Disease Control and Prevention. This photo shows perianal granuloma inguinale. Image courtesy of Dr. Tabua via the Public Health Image Library of the Centers for Disease Control and Prevention. Granuloma inguinale is a progressive ulcerative disease that is usually sexually transmitted and involves the skin and subcutaneous tissues in the anogenital and inguinal regions. The initial nodule slowly enlarges, erodes the surrounding tissues, and develops into a beefy, bulky, granulomatous mass. © Springer Science+Business Media 