hepatic and biliary disorders
Postoperative Liver Dysfunction
Postoperative cholestasis
The most common cause of postoperative cholestasis is extrahepatic biliary obstruction due to intra-abdominal complications or drugs given postoperatively. Intrahepatic cholestasis occasionally develops after major surgery, especially after abdominal or cardiovascular procedures (benign postoperative intrahepatic cholestasis). The pathogenesis is unknown, but the condition usually resolves slowly and spontaneously. Occasionally, postoperative cholestasis results from acute acalculous cholecystitis or pancreatitis. 