infectious diseases
Sporotrichosis
Treatment of Sporotrichosis
Itraconazole Oralitraconazole200 mg orally once a day given until 2 to 4 weeks after all lesions have resolved (typically 3 to 6 months) is the treatment of choice. Severe infection requires a lipid formulation ofamphotericin B(3 to 5 mg/kg IV once a day); after a favorable response, treatment is switched to oralitraconazolefor a total of 12 months of treatment. Patients with AIDS may require lifelong maintenance therapy withitraconazolefor meningeal and disseminated infection.Posaconazolemay have a role. 