infectious diseases
Polypeptide Antibiotics: Bacitracin, Colistin, Polymyxin B
Adverse Effects of Polypeptide Antibiotics
Adverse effects of polypeptides include Nephrotoxicity Central and peripheral neurotoxicity Polymyxins are nephrotoxic. CMS andpolymyxin Bmay cause circumoral and extremity paresthesias, vertigo, slurred speech, and muscle weakness and respiratory difficulty due to neuromuscular blockade, especially in patients with renal insufficiency. 