gynecology and obstetrics
Nipple Discharge
Key Points
Nipple discharge is most often benign. Bilateral, multiductal, guaiac-negative discharge is usually benign and has an endocrine etiology. Spontaneous, unilateral discharge requires diagnostic testing; this type of discharge may be cancer, particularly if it is bloody (or guaiac-positive). Presence of a breast mass, a bloody (or guaiac-positive) discharge, or history of an abnormality on a mammogram or an ultrasound scan requires follow-up with a surgeon who is experienced with breast disorders. 