neurologic disorders
Hereditary Spastic Paraplegia
Treatment of Hereditary Spastic Paraplegia
Symptomatic, including medications to relieve spasticity Treatment for all forms of hereditary spastic paraplegia is symptomatic.Baclofen10 mg orally twice a day, increased as needed up to 40 mg orally twice a day, is given for spasticity. Alternatives includediazepam,clonazepam,dantrolene, botulinum toxin (botulinum toxin type A or botulinum toxin type B), andtizanidine. Physical therapy and exercise can help maintain mobility and muscle strength, improve range of motion and endurance, reduce fatigue, and prevent spasms. Some patients benefit from using splints, a cane, or crutches. 