infectious diseases
Amebic Keratitis
Treatment of Amebic Keratitis
Corneal debridement Topicalchlorhexidine, polyhexamethylene biguanide, or both Early, superficial amebic keratitis responds better to treatment. Epithelial lesions are debrided, and intensive drug therapy is applied. The initial choice is Topicalchlorhexidine0.02% Topical polyhexamethylene biguanide 0.02% Both drugs For the first 3 days, treatment is given every 1 to 2 hours. Other topical medications used as adjunct therapy include the diamidines propamidine (0.1%) or hexamidine (0.1%). Early recognition and treatment have eliminated the need for therapeutic keratoplasty in most instances, but keratoplasty remains an option when pharmacologic therapy fails. Intensive treatment is required for the first month; it is tapered per clinical response but continued for 6 to 12 months. Recurrence is common if treatment is stopped prematurely. 