infectious diseases
Haemophilus influenzae Type b (Hib) Vaccine
Preparations of Hib Vaccine
Haemophilus influenzaetype b (Hib) vaccines are prepared from the purified capsule ofHaemophilus influenzaetype b. All Hib vaccines use polyribosylribitol phosphate (PRP) as the polysaccharide, but 4 different protein carriers are used in the 4 different Hib conjugate vaccines available: Diphtheria toxoid (PRP-D) Neisseria meningitidisouter membrane protein (PRP-OMP) Tetanus toxoid (PRP-T) Diphtheria mutant carrier protein CRM197 (HbOC) PRP-D and HbOC vaccines are no longer available in the United States. The following combination vaccines contain Hib conjugate vaccines: Diphtheria toxoid/Haemophilusinfluenzae type b conjugate vaccine/hepatitis B vaccine/inactivated poliovirus vaccine Diphtheria toxoid/Haemophilusinfluenzae type B conjugate vaccine/inactivated poliovirus vaccine Diphtheria/tetanus toxoids/pertussis vaccine/Haemophilusinfluenzae type b conjugate vaccine MeningococcalHaemophilusinfluenzae type b conjugate vaccine 