drugs
Risk Factors for Adverse Drug Reactions
Introduction
Many factors can increase the likelihood of an Overview of Adverse Drug Reactions (any unwanted effects of a drug or medication). They include Hereditary factors Certain preexisting diseases Types of Adverse Drug Reactions None Very young or old age Pregnancy Breastfeeding Hereditary factorsmake some people more susceptible to the toxic effects of certain drugs (including medications). Various genes have been identified that affect how the body responds to drugs. For example, differences in certain genes can affect metabolism of drugs in the liver, allowing drug levels to rise and increase the chances of an adverse drug reaction. However, testing for these differences is complex and is not yet used routinely in clinical practice. can alter drug absorption, metabolism, and elimination and the body's response to drugs (see Drug-Disease Interactions ), increasing the risk of adverse drug reactions. How mind-body interactions, such as mental attitude, outlook, belief in self, and confidence in health care practitioners, influence adverse drug reactions remains largely unexplored. 