genitourinary disorders
Metabolic Nephropathies
Chronic hypokalemia
Chronic Hypokalemia of a moderate to severe degree may cause nephropathy with impaired urinary concentration and vacuolation of proximal tubular cells and occasionally of distal tubular cells. Diagnosis is suggested by history of prolonged severe hypokalemia. Treatment consists of correction of the underlying disorder and oral potassium supplements. Although the hypokalemia as well as the number and size of the cysts are reversible, the chronic tubulointerstitial nephropathy and renal insufficiency may be irreversible. 