hematology and oncology
Splenomegaly
Treatment of Splenomegaly
Treatment of underlying disorder Treatment is directed at the underlying disorder. An enlarged spleen itself in an asymptomatic patient needs no treatment unless severe Hypersplenism or early satiety due to encroachment on the stomach is present. Patients with palpable or very large spleens probably should avoid contact sports and weight-lifting to decrease the risk of splenic rupture. 