hepatic and biliary disorders
Sinusoidal Obstruction Syndrome
Introduction
Hepatic sinusoidal obstruction syndrome is caused by endothelial injury, leading to nonthrombotic occlusion of the terminal hepatic venules and hepatic sinusoids, rather than of the hepatic veins or inferior vena cava (as in Budd-Chiari Syndrome ). (See also Overview of Vascular Disorders of the Liver .) Venous congestion causes Portal Hypertension and ischemic necrosis (which leads to 