hematology and oncology
Cellular and Molecular Basis of Cancer
Immune Disorders
Immune system dysfunction as a result of inherited genetic mutation, acquired disorders, aging, or immune-suppressing drugs interferes with normal immune surveillance of early tumors and results in higher rates of cancer. Known cancer-associated immune disorders include Ataxia-Telangiectasia (acute lymphocytic leukemia [ALL], brain tumors, gastric cancer) Wiskott-Aldrich Syndrome (lymphoma, ALL) X-linked Agammaglobulinemia (lymphoma, ALL) Immune deficiency resulting from immune-suppressing drugs or HIV infection (lymphoma, kidney cancer, melanoma, cervical cancer, head and neck cancer, Kaposi sarcoma) Autoimmune disorders such as Systemic Lupus Erythematosus (SLE) , 