gynecology and obstetrics
Sperm Disorders
Treatment of Sperm Disorders
Clomiphene Assisted reproductive techniques ifclomipheneis ineffective Underlying genitourinary disorders are treated. If infection is detected, appropriate antibiotics are given. For men with sperm counts of 10 to 20 million/mL and no endocrine disorder,clomiphenecitrate (25 to 50 mg orally once a day taken 25 days/month for 3 to 4 months) can be tried.Clomiphene, an antiestrogen, may stimulate sperm production and increase sperm counts. However, whether it improves sperm motility or morphology is unclear, and it has not been proved to increase fertility. is unsuccessful in men with normal sperm motility, the most effective treatment is usually in vitro fertilization with injection of a single sperm into a single egg ( Intracytoplasmic sperm injection (ICSI) ). (Because this procedure is widely used, sperm penetration assays are rarely done now.) Alternatively, intrauterine insemination using washed semen samples and timed to coincide with ovulation is sometimes tried. If pregnancy is going to occur, it usually occurs by the 6th treatment cycle, but this treatment is only somewhat effective. Decreased number and viability of sperm may not preclude pregnancy. In such cases, fertility may be enhanced by Treatment of the woman plus artificial insemination or 6 months, after which donors are retested for infection before insemination proceeds. In the US, the Centers for Disease Control and Prevention (CDC) recommends postponing collection of semen for 6 months if donors have been diagnosed with Prevention infection or have lived in or traveled to an area with active Zika virus transmission. 