genitourinary disorders
Postinfectious Glomerulonephritis (PIGN)
Symptoms and Signs of Postinfectious Glomerulonephritis
Symptoms and signs range from asymptomatic hematuria (in about 50%) and mild proteinuria to full-blown nephritis with microscopic or gross hematuria (cola-colored, brown, smoky, or frankly bloody urine), proteinuria (sometimes nephrotic-range), oliguria, edema, hypertension, and renal insufficiency. Fever is unusual and suggests persistent infection. Renal failure that causes fluid overload with heart failure and severe hypertension requiring dialysis affects 1 to 2% of patients. Uncommonly, nephrotic syndrome may persist after resolution of severe disease. Clinical manifestations of nonstreptococcal PIGN may mimic other disorders (eg, Polyarteritis Nodosa (PAN) , renal emboli, antimicrobial drug–induced acute interstitial nephritis). 