eye disorders
Retinitis Pigmentosa
Key Points
Early symptoms of retinitis pigmentosa include defective night vision and peripheral vision. Diagnose by hyperpigmentation in a bone-spicule configuration on funduscopy and confirm with electroretinography. Prescribevitamin A, omega 3 fatty acids, and lutein and zeaxanthin supplements to decrease rate of vision loss. Treat patients with cystoid macular edema with carbonic anhydrase inhibitors. Gene therapy withvoretigene neparvovec-rzyl can restore ambulatory vision in patients with confirmed biallelic RPE65 mutation-associated retinal dystrophy. 