hormonal and metabolic disorders
Amyloidosis
Causes of Amyloidosis
Proteins are long chains of molecules that fold up into a certain shape. The exact shape is critical to how each protein functions. All types of amyloidosis involve a protein that folds abnormally. The abnormally folded proteins clump together and accumulate in various body tissues as amyloid deposits. These deposits are made up of amyloid fibrils, which contain abnormal protein fibers that cannot be easily broken down by the body. These deposits interfere with normal function of the organ where they are located. All of these proteins are produced within the body and do not come from a person's diet. Some amyloid proteins are mutated versions of normal proteins. Others are normal proteins that simply have a tendency to fold abnormally. Some of the proteins are produced in various other diseases (such as Tuberculosis (TB) or 