digestive disorders
Stomach Cancer
Risk Factors for Stomach Cancer
Adenocarcinoma of the stomach often begins at a site where the stomach lining is inflamed. Helicobacter pylori Infection is a risk factor for some stomach cancers because it causes stomach inflammation. Causes is a risk factor for stomach cancer. Stomach polyps may become cancerous (malignant) and are thus removed. Adenocarcinoma of the stomach is particularly likely to develop if the polyps consist of glandular cells (adenomatous polyps) or if the polyps are larger than ¾ inch (2 centimeters). People who have certain gene mutations are also at risk. Hereditary diffuse gastric cancer is a rare inherited disorder that increases a person's risk of developing stomach cancer. It is caused by a mutation in a certain gene. Affected people usually develop stomach cancer at an early age (average age 38). Affected women are also at high risk of developing cancer of the milk-producing glands (lobular breast cancer). People who have had stomach cancer, lobular breast cancer, or both or who have multiple family members who have had these cancers should receive genetic counseling and testing, especially if they were diagnosed before age 50. Other inherited disorders that may increase the risk of stomach cancer include Hereditary conditions that cause intestinal polyps , Certain dietary factors were once thought to play a role in the development of adenocarcinoma of the stomach. These factors included a high intake of salt, a high intake of carbohydrates, a high intake of preservatives called nitrates (often present in smoked foods), and a low intake of fruit and green leafy vegetables. Although none of these factors has proved to be a cause, a direct link between the consumption of processed meat and stomach cancer has been reported. Smoking is a risk factor for stomach cancer. People who smoke may not respond as well to treatment. 