infectious diseases
Granulomatous Amebic Encephalitis
Symptoms of Granulomatous Amebic Encephalitis
In patients with granulomatous amebic encephalitis, onset is insidious, often with focal neurologic manifestations. Mental status change, seizures, and headache are common. Acanthamoebaspecies andB. mandrillarismay also cause skin lesions; patients can present with ulcerative skin lesions and later develop neurologic symptoms and signs. In a few patients with AIDS, disseminatedAcanthamoebainfection has affected only the skin. Survival is uncommon in patients with central nervous system or disseminated disease; death usually occurs between 7 and 120 days after onset. 