musculoskeletal and connective tissue disorders
Reactive Arthritis
Etiology of Reactive Arthritis
Two forms of reactive arthritis are common: sexually transmitted and dysenteric. The sexually transmitted form occurs primarily in men aged 20 to 40. Genital infections withChlamydia trachomatisare most often implicated. Men or women can acquire the dysenteric form after enteric infections, primarilyShigella,Salmonella,Clostridioides difficile,Yersinia, orCampylobacter. Bacille Calmette-Guerin injection for bladder cancer has also been reported to trigger reactive arthritis. In approximately in 40% of cases, infectious pathogens cannot be identified. Reactive arthritis is postinfectious arthritis. Although there is evidence of microbial antigens in the synovium, organisms cannot be cultured from joint fluid. 