pulmonary disorders
Allergic Bronchopulmonary Aspergillosis (ABPA)
Key Points
Consider allergic bronchopulmonary aspergillosis (ABPA) if a patient with asthma or cystic fibrosis develops frequent exacerbations for unclear reasons, has migratory or nonresolving infiltrates on chest x-ray, has evidence of bronchiectasis on imaging studies, has persistent blood eosinophilia, or if a sputum culture revealsAspergillus. Begin testing with a skin prick usingAspergillusantigen, followed usually by serologic testing. Treat initially withprednisone. If ABPA persists despiteprednisone, treat with an antifungal such asitraconazole. 