gynecology and obstetrics
Pemphigoid Gestationis
Diagnosis of Pemphigoid Gestationis
Characteristic skin lesions Sometimes biopsy with direct immunofluorescence Pemphigoid gestationis may be confused clinically with several other pruritic eruptions of pregnancy, particularly Polymorphic Eruption of Pregnancy . Pemphigoid gestationis can often be distinguished because it usually begins in the periumbilical area; polymorphic eruption of pregnancy usually begin in the striae. Direct immunofluorescence examination of perilesional skin is diagnostic. It detects a linear band of C3 at the basement membrane zone. 