infectious diseases
Manifestations of Infection
Other organ systems
 compliance may decrease, progressing to Acute Hypoxemic Respiratory Failure (AHRF, ARDS) (ARDS) and respiratory muscle failure. manifestations range from minimal proteinuria to Acute Kidney Injury (AKI) , which can result from shock and acute tubular necrosis, glomerulonephritis, or tubulointerstitial disease. Hepaticdysfunction, including cholestatic jaundice (often a poor prognostic sign) or hepatocellular dysfunction, occurs with many infections, even though the infection does not localize to the liver. Gastrointestinal(GI) manifestations include upper GI bleeding due to stress ulceration that may occur during sepsis. Endocrinologicdysfunctions include Increased production of thyroid-stimulating hormone,vasopressin,insulin, andglucagon Breakdown of skeletal muscle proteins and muscle wasting secondary to increased metabolic demands Bone demineralization Hypoglycemia occurs infrequently in sepsis, but adrenal insufficiency should be considered in patients with hypoglycemia and sepsis. 