immunology allergic disorders
Hyper IgE Syndrome
Treatment of Hyper IgE Syndrome
Prophylactic antistaphylococcal antibiotics Sometimes interferon gamma for severe infection Treatment of hyper-IgE syndrome consists of lifelong prophylactic antistaphylococcal antibiotics (usuallytrimethoprim/sulfamethoxazole). Dermatitis is treated with skin hydration, emollient creams, antihistamines. and, if infections are suspected, antibiotics. Pulmonary infections are treated early and aggressively with antibiotics. Significant Osteoporosis should be screened for and managed under current guidelines for patients without a primary immunodeficiency disorder. Interferon gamma has been used successfully for life-threatening infections. 