hematology and oncology
Polycythemia Vera
Prognosis for Polycythemia Vera
A large study of patients with polycythemia vera reported a median survival of 14.1 years, and this was significantly worse than that of an age- and sex-matched control population ( Prognosis reference ). Thrombosis is the most common cause of morbidity and death, followed by the complications of myelofibrosis and development of leukemia. Gene mutations and cytogenetic abnormalities may aid in the identification of prognostic subgroups. 1.Tefferi A, Rumi E, Finazzi G, et al: Survival and prognosis among 1545 patients with contemporary polycythemia vera: an international study.Leukemia27(9):1874–1881, 2013. doi:10.1038/leu.2013.163 