musculoskeletal and connective tissue disorders
Immunoglobulin A–Associated Vasculitis (IgAV)
Key Points
Immunoglobulin A–associated vasculitis is vasculitis that affects primarily small vessels and occurs more frequently in children than adults. Manifestations can include purpuric rash, arthralgias, fever, abdominal pain, melena, and glomerulonephritis. Symptoms usually remit after about 4 weeks. When necessary to confirm the diagnosis, biopsy skin lesions, looking for IgA deposition. Treat symptoms and, for adults, consider corticosteroids with or without an immunosuppressant. 