hematology and oncology
Essential Thrombocythemia
Pathophysiology of Essential Thrombocythemia
Thrombocythemia may lead to Microvascular occlusions Large vessel thrombosis Bleeding Microvascular occlusions involve small vessels of the distal extremities (causing Erythromelalgia ), the eye (causing ocular It is unclear whether the risk of large vessel thrombosis causing Deep Venous Thrombosis (DVT) or caused because the platelets adsorb and proteolyze high molecular weight von Willebrand multimers, causing type 2 acquired Von Willebrand Disease . 