genitourinary disorders
Thin Basement Membrane Disease
Introduction
Thin basement membrane disease is diffuse thinning of the glomerular basement membrane from a width of 300 to 400 nm in normal subjects to 150 to 225 nm. Thin basement membrane disease is a type of Overview of Nephritic Syndrome . It is hereditary and usually transmitted in autosomal dominant fashion. Not all genetic mutations have been characterized, but in some families with thin basement membrane disease there is a mutation in the type IV collagen 