pediatrics
Mumps
Prevention of Mumps
Vaccination with Measles, Mumps, and Rubella (MMR) Vaccine (see also Two doses are recommended: The first dose at age 12 to 15 months The second dose at age 4 to 6 years Infants immunized at<1 year of age still require 2 additional doses given after their first birthday. C occurs 5 to 12 days after inoculation in 5 to 15% of vaccinees and can be followed by a rash. Central nervous system reactions are exceedingly rare. The Measles-Mumps-Rubella (MMR) Vaccine . Vaccination generally provides lasting immunity ( Prevention references ). A large meta-analysis of cohort studies found the effectiveness of the MMR vaccine in preventing mumps in children from age 9 months to 15 years was 72% after one dose and 86% after two doses ( MMR is a live vaccine and is contraindicated during pregnancy. See Measles, Mumps, and Rubella (MMR) Vaccine for more information, including Postexposure vaccination does not protect against mumps from that exposure. Mumps immune globulin is no longer available, and serum immune globulin is not helpful. The CDC recommends isolation of infected patients with standard and respiratory droplet precautions for 5 days after the onset of parotitis. Susceptible contacts should be vaccinated, and a third dose is recommended for previously immunized people at increased risk of mumps during an outbreak, as determined by public health officials. Robust data are lacking, but a third dose and additional measures may help control an outbreak ( Prevention references ). Nonimmune asymptomatic health care professionals should be excused from work from 12 days after the initial exposure through 25 days after the last exposure. 1.McLean HQ, Fiebelkorn AP, Temte JL, Wallace GS; Centers for Disease Control and Prevention: Prevention of measles, rubella, congenital rubella syndrome, and mumps, 2013: Summary recommendations of the Advisory Committee on Immunization Practices (ACIP).MMWR Recomm Rep62(RR-04):1–34, 2013. 2.Di Pietrantonj C, Rivetti A, Marchione P, et al: Vaccines for measles, mumps, rubella, and varicella in children.Cochrane Database Syst Rev4(4):CD004407, 2020. doi: 10.1002/14651858.CD004407.pub4 3.Marin M, Marlow M, Moore KL, Patel M: Recommendation of the Advisory Committee on Immunization Practices for use of a third dose of mumps virus–containing vaccine in persons at increased risk for mumps during an outbreak.MMWR Morb Mortal Wkly Rep67:33–38, 2018. doi: 10.15585/mmwr.mm6701a7 