gastrointestinal disorders
Overview of Inflammatory Bowel Disease
Extraintestinal Manifestations of Inflammatory Bowel Disease
Crohn disease and ulcerative colitis both affect organs other than the intestines. Most extraintestinal manifestations are more common in ulcerative colitis and Crohn colitis than in Crohn disease limited to the small bowel. Extraintestinal manifestations of inflammatory bowel disease are categorized in 3 ways: These disorders include peripheral arthritis, Episcleritis , These disorders include Ankylosing Spondylitis sacroiliitis, These disorders occur mainly in severe Crohn disease of the small bowel. Overview of Malabsorption may result from extensive ileal resection and cause deficiencies of fat-soluble vitamins, vitamin B12, or minerals, resulting in anemia, hypocalcemia, hypomagnesemia, clotting disorders, and bone demineralization. In children, malabsorption retards growth and development. Other disorders include kidney stones resulting from excessive dietary oxalate absorption, hydroureter and hydronephrosis resulting from ureteral compression by the intestinal inflammatory process, gallstones resulting from impaired ileal reabsorption of bile salts, and amyloidosis secondary to long-standing inflammatory and suppurative disease. Thromboembolic disease may occur as a result of multiple factors in all 3 categories. 