cardiovascular disorders
Restrictive Cardiomyopathy
Treatment of Restrictive Cardiomyopathy
Cause treated Diuretics considered If the diagnosis is made at an early stage, specific treatment of some underlying causes, such as Amyloidosis , Diuretics may be used for patients with edema or pulmonary vascular congestion but must be given cautiously because they can lower preload; the noncompliant ventricles depend on preload to maintain cardiac output. Digoxindoes little to alter hemodynamic abnormalities and may cause serious arrhythmias in cardiomyopathy due to amyloidosis, in which extreme digitalis sensitivity is common. If heart rate is elevated, beta-blockers or rate-limiting calcium channel blockers may be used cautiously in low doses. Afterload reducers (eg, nitrates) may cause profound hypotension and usually are not useful. Left ventricular assist device (LVAD) and transplantation are sometimes recommended ( Treatment reference ). 1.Muchtar E, Blauwet LA, Gertz MA: Restrictive cardiomyopathy: Genetics, pathogenesis, clinical manifestations, diagnosis, and therapy.Circ Res121:819–837, 2017. doi: 10.1161/CIRCRESAHA.117.310982 