immunology allergic disorders
Hyper IgE Syndrome
Symptoms and Signs of Hyper IgE Syndrome
Hyper-IgE syndrome typically causes recurrent staphylococcal abscesses of the skin, lungs, joints, and viscera. Patients may also have sinopulmonary infections, pulmonary pneumatoceles, and a severe pruritic eosinophilic dermatitis. Patients have coarse facial features, delayed shedding of baby teeth, osteopenia, and recurrent fractures. 