gynecology and obstetrics
Pemphigoid Gestationis
Treatment of Pemphigoid Gestationis
Corticosteroids topically or, for severe symptoms, orally Nonsedating oral antihistamines For mild symptoms, topical corticosteroids (eg, 0.1%triamcinoloneacetonide cream up to 6 times a day) may be effective.Prednisone(eg, 40 mg orally once a day) relieves moderate or severe pruritus and prevents new lesions; dose is tapered until few new lesions erupt, but it may need to be increased if symptoms become more severe (eg, during labor). Systemic corticosteroids given late in pregnancy and in short bursts, do not seem to harm the fetus. Nonsedating oral antihistamines can also be used to relieve pruritus. Fetal status may be monitored with ultrasonography every 4 weeks if growth is normal or every 2 weeks if growth is restricted. Fetal Monitoring is also done when growth is restricted. 