hematology and oncology
Paraneoplastic Syndromes
General paraneoplastic symptoms
Patients with cancer often experience fever, night sweats, anorexia, and cachexia. These symptoms may arise from release of cytokines involved in the inflammatory or immune response or from mediators involved in tumor cell death, such as tumor necrosis factor-alpha. Alterations in liver function and steroidogenesis may also contribute. 