injuries poisoning
How To Do Procedural Sedation and Analgesia
Complications
Respiratory depression Oxygen desaturation Hypotension (rarely significant in the absence of concurrent serious disease or cardiovascular compromise) Aspiration (rare) Particular toetomidate: Myoclonus (minimal and brief, rarely clinically significant); adrenal suppression (usually inconsequential and transient) Particular tofentanyl: Chest wall rigidity (rigid chest syndrome) due to too-rapid IV push (infrequent at the low dose used for analgesia) Particular toketamine: Occasional laryngospasm or apnea (prevented by adhering to slow push [>30 to 60 seconds]); sympathomimetic effects (hypertension, tachycardia, which pose risk to patients with ischemic heart disease or underlying hypertension); on recovery, vomiting or emergence reactions (anxiety/panic/hallucinatory episode), more frequent in adults than in children 