infectious diseases
Mycoplasmas
Treatment of Mycoplasmas
Macrolide antibiotics Fluoroquinolones or tetracyclines Macrolides are usually the antimicrobials of choice. Most species are also sensitive to fluoroquinolones and tetracyclines. has been reported in > 80% of isolates in China and Japan. Preliminary data show the prevalence of resistance may be as high as 12% in the United States ( Treatment reference ). Therefore, fluoroquinolones or tetracyclines should be considered in patients with refractory disease, especially in areas with significant macrolide resistance. M. genitaliumhas been developing widespread resistance to macrolides, tetracyclines, and fluoroquinolones, which makes treating infection with this organism a challenge. NAATs to detect macrolide resistance inM. pneumoniaeandM. genitaliumare currently being developed. 1.Centers for Disease Control and Prevention:M. pneumoniaeinfection: Antibiotic Treatment and Resistance. Accessed 03/30/2023. 