pulmonary disorders
Treatment of Acute COPD Exacerbation
Key Points
Most patients with exacerbation of chronic obstructive pulmonary disease (COPD) require oxygen supplementation during an exacerbation. Inhaled short-acting beta-agonists are the cornerstone of drug therapy for acute exacerbations. Use antibiotics if patients have acute exacerbations and purulent sputum. For patients with end stage COPD, address end-of-life care proactively, including preferences regarding mechanical ventilation and palliative sedation. 