musculoskeletal and connective tissue disorders
Pain in and Around a Single Joint
Pathophysiology of Pain in a Single Joint
Pain in and around a joint may involve Inflammation (due to, eg, infection, crystal-induced arthritis, or autoimmune systemic inflammatory disorders) Noninflammatory problems, usually mechanical (eg, trauma, internal derangements) The synovium and joint capsule are major sources of intra-articular pain. The synovial membrane is the main site affected by inflammation (synovitis). Pain that originates from the menisci is more likely to be a result of injury. 