endocrine and metabolic disorders
Addison Disease
Etiology of Addison Disease
About 70% of cases in the US are due to idiopathic atrophy of the adrenal cortex, probably caused by autoimmune processes. The remainder result from destruction of the adrenal gland by granuloma (eg, Tuberculosis (TB) , Addison disease may coexist with diabetes mellitus or hypothyroidism in Polyglandular Deficiency Syndromes . In children, the most common cause of primary adrenal insufficiency is 