infectious diseases
Postpoliomyelitis Syndrome
Introduction
Postpoliomyelitis syndrome is a group of symptoms that develops years or decades after paralytic poliomyelitis and usually affects the same muscle groups as the initial infection. In patients who have had Pathophysiology , muscle fatigue and decreased endurance, often accompanied by weakness, fasciculations, and atrophy, may develop years or decades later, particularly in older patients and in patients who were severely affected initially. Damage usually occurs in previously affected muscle groups. However, postpoliomyelitis syndrome rarely increases disability substantially. (See also The cause of postpoliomyelitis syndrome may be related to further loss of anterior horn cells due to aging in a population of neurons already depleted by earlier poliovirus infection. Treatmentof postpoliomyelitis syndrome is supportive. 