neurologic disorders
Neuropathic Pain
Introduction
Neuropathic pain results from damage to or dysfunction of the peripheral or central nervous system, rather than stimulation of pain receptors. Diagnosis is suggested by pain out of proportion to tissue injury, dysesthesia (eg, burning, tingling), and signs of nerve injury detected during neurologic examination. Treatment is often with adjuvant drugs rather than analgesics (eg, antidepressants, antiseizure drugs,baclofen, topical drugs) or with nondrug treatments (eg, physical therapy, neuromodulation). (See also Overview of Pain .) Pain can develop after injury to any level of the nervous system, peripheral or central; the sympathetic nervous system may be involved (causing sympathetically maintained pain). Specific syndromes include Postherpetic neuralgia None Root avulsions Painful traumatic mononeuropathy Painful polyneuropathy (including Diabetic Nephropathy or chemotherapy) Central pain syndromes (potentially caused by virtually any lesion at any level of the nervous system) Postsurgical pain syndromes (eg, postmastectomy syndrome, postthoracotomy syndrome, Pain in the Residual Limb ) Complex Regional Pain Syndrome (CRPS) (reflex sympathetic dystrophy and causalgia) 