genitourinary disorders
Renal Cell Carcinoma
Signs and Symptoms of Renal Cancer
Symptoms usually do not appear until late, when the tumor may already be large and metastatic. Gross or microscopic hematuria is the most common manifestation, followed by flank pain, fever of unknown origin (FUO), and a palpable mass. Other nonspecific symptoms can include fatigue, weight loss, and early satiety. Sometimes hypertension results from segmental ischemia or pedicle compression. Paraneoplastic Syndromes occur in 20% of patients. Polycythemia can result from increased erythropoietin activity. However, anemia may also occur. 