cardiovascular disorders
Lymphedema
Key Points
Secondary lymphedema (due to obstruction or disruption of lymphatic vessels) is far more common than primary lymphedema (which is due to lymphatic hypoplasia). Elephantiasis (extreme hyperkeratosis of skin in a limb affected by lymphedema) is a severe manifestation of lymphedema usually due to lymphatic filariasis. Cure is unusual, but treatment can decrease symptoms, slow or halt disease progression, and prevent complications. 