infectious diseases
Lipoglycopeptides
Indications for Lipoglycopeptides
Lipoglycopeptides are broadly active against gram-positive bacteria, including Streptococcal Infections None Enterococcal Infections None Enterococcus faecium Staphylococcal Infections , including Oritavancinis active againstvancomycin-resistant enterococci (VRE) strains that harbor thevanAgene;dalbavancinandtelavancinare not.Dalbavancin,oritavancin, andtelavancinhave activity againstvanBVRE. All three lipoglycopeptides are active againstStaphylococcus aureusandStaphylococcus epidermidisregardless of their susceptibility to methicillin. Onlyoritavancinis active againstvancomycin-resistantS. aureus. is used for complicated skin and skin structure infections as well as for Hospital-Acquired Pneumonia caused by sensitive isolates of The long-acting lipoglycopeptidesdalbavancinandoritavancinare used to treat acute bacterial skin and skin structure infections but are still being studied as treatment for more invasive infections. 