infectious diseases
Penicillins
Pharmacokinetics
Food does not interfere with absorption ofamoxicillin, butpenicillin Gshould be given 1 hour before or 2 hours after a meal.Amoxicillinhas generally replacedampicillinfor oral use becauseamoxicillinis absorbed better, has fewer gastrointestinal effects, and can be given less frequently. Penicillins are distributed rapidly in the extracellular fluid of most tissues, particularly when inflammation is present. , which can be detected for 30 days ( Pharmacokinetics reference ). 1.Centers for Disease Control and Prevention (CDC): Inadvertent use of Bicillin C-R to treat syphilis infection—Los Angeles, California, 1999-2004.MMWR Morb Mortal Wkly Rep54(9):217–219, 2005. PMID: 15758893 