infectious diseases
Ehrlichiosis and Anaplasmosis
Key Points
Ehrlichiosis and anaplasmosis are tick-borne infections related to Overview of Rickettsial and Related Infections . Clinical features of ehrlichiosis and anaplasmosis are similar, usually with abrupt onset of an influenza-like illness; rash is uncommon in anaplasmosis. Ehrlichiosis and anaplasmosis may result in disseminated intravascular coagulation, multiorgan failure, seizures, and coma. Do PCR testing of blood, which is more sensitive and specific than serologic tests and can result in an early diagnosis. Treat withdoxycycline, best started before laboratory results return. 