infectious diseases
Coccidioidomycosis
Key Points
Coccidioidomycosis is a common fungal infection acquired by inhaling spore-laden dust. It is endemic to the southwestern United States and northern Mexico; disease also occurs in certain parts of Central and South America. Most patients have an asymptomatic or mild pulmonary infection, but those who are immunocompromised or have other risk factors may develop severe, progressive pulmonary disease or disseminated infection (typically to skin, bone, or meninges). Diagnose using culture, staining, and/or serologic testing. For mild to moderate disease, usefluconazoleoritraconazole. For severe disease, use a lipid formulation ofamphotericin B. 