infectious diseases
Metronidazole and Tinidazole
Adverse Effects ofMetronidazoleandTinidazole
Adverse effects ofmetronidazoleandtinidazoleinclude Gastrointestinal disturbances Central nervous system effects and peripheral neuropathy Disulfiram-like reaction Nausea, vomiting, headache, seizures, syncope, other central nervous system effects, and peripheral neuropathy can occur; rash, fever, and reversible neutropenia have been reported.Metronidazolecan cause a metallic taste and dark urine. Adisulfiram-like reaction (including flushing, headache, nausea, and vomiting) may occur if alcohol is ingested within 7 days of use. Tinidazolemay have a slightly lower incidence of gastrointestinal disturbance. 