clinical pharmacology
Chemical Interactions
Introduction
Some drugs produce effects without altering cellular function and without binding to a receptor. For example, most antacids decrease gastric acidity through simple chemical reactions; antacids are bases that chemically interact with acids to produce neutral salts. The primary action ofcholestyramine, a bile acid sequestrant, is to bind bile acids in the gastrointestinal tract. (See also Overview of Pharmacodynamics .) 