pediatrics
Osteochondrodysplasias (Osteochondrodysplastic Dwarfism)
Key Points
Osteochondrodysplasias are inherited abnormalities of growth and development of connective tissue, bone, and/or cartilage. There are many types, which differ widely in genetic background, course, and prognosis, but all cause markedly short stature and often disproportionate growth of the trunk and extremities. Diagnosis is by clinical manifestations and identification of characteristic x-ray changes. Growth hormone treatments are typically ineffective. 