nutritional disorders
Vitamin E Deficiency
Symptoms and Signs ofVitamin EDeficiency
The main symptoms ofvitamin Edeficiency are mild hemolytic anemia and nonspecific neurologic deficits. Abetalipoproteinemia results in progressive neuropathy and retinopathy in the first 2 decades of life. deficiency may contribute to Retinopathy of Prematurity (also called retrolental fibroplasia) in premature infants and to some cases of intraventricular and subependymal hemorrhage in neonates. Affected premature neonates have muscle weakness. In children, chronic cholestatic hepatobiliary disease or cystic fibrosis causes neurologic deficits, including spinocerebellar ataxia with loss of deep tendon reflexes, truncal and limb ataxia, loss of vibration and position senses, ophthalmoplegia, muscle weakness, ptosis, and dysarthria. In adults with malabsorption,vitamin Edeficiency very rarely causes spinocerebellar ataxia because adults have largevitamin Estores in adipose tissue. 