injuries poisoning
Approach to the Trauma Patient
Pathophysiology
All injuries, by definition, causedirecttissue damage, the nature and extent depending on the anatomic site, mechanism, and intensity of trauma. Severe direct tissue damage to critical organs (eg, to the heart, brain, spinal cord) is responsible for most immediate trauma deaths. 10% of blood volume) are tolerated well by most patients. Larger amounts cause progressive declines in blood pressure and organ perfusion ( Shock ), leading to cellular dysfunction, organ failure, and eventually death. Hemorrhagic shock and 