children s health issues
Overview of Chromosomal Deletion Syndromes
Introduction
Chromosomal deletion syndromes occur when part of a chromosome is missing. (See also Overview of Chromosome and Gene Disorders .) Chromosomes are structures within cells that contain Genes are segments of deoxyribonucleic acid (DNA) and contain the code for a specific protein that functions in one or more types of cells in the body. Genes contain instructions that determine how the body is supposed to look and function. (See When parts of chromosomes are missing, a number of syndromes can occur. These syndromes are called chromosomal deletion syndromes. They tend to cause Overview of Birth Defects , There are many chromosomal deletion syndromes, which include Cri-du-Chat Syndrome None Prader-Willi Syndrome None Wolf-Hirschhorn Syndrome None Chromosomal deletion syndromes may be suspected before birth or after birth. The diagnosis of these syndromes is confirmed by chromosomal testing. (See also Next-generation sequencing technologies .) Some physical defects can be corrected with surgery, but generally treatment is supportive. 