blood disorders
Heavy Chain Diseases
Mu Heavy Chain Disease
Mu heavy chain disease (IgM heavy chain disease), the rarest of the three main heavy chain diseases, most often affects people over 50. It may cause enlargement of the liver and spleen as well as enlargement of the lymph nodes in the abdomen. Fractures and Amyloidosis may also occur. Blood and urine tests are typically done. Bone marrow examination is usually needed for diagnosis. Treatment usually includes chemotherapy drugs and corticosteroids. Length of survival and response to treatment vary widely. 