gynecology and obstetrics
Uterine Sarcomas
Key Points
Uterine sarcomas are uncommon. Symptoms include abnormal vaginal bleeding, a mass in the vagina, pelvic pain, a feeling of fullness in the abdomen, and frequent urination. Prognosis is generally worse than that with endometrial carcinoma of similar stage. Treat most patients with total abdominal hysterectomy, bilateral salpingo-oophorectomy, and adjuvant radiation. Treat patients who have endometrial stroma sarcoma and hormone receptor–positive leiomyosarcomas with endocrine therapy. Treat inoperable sarcomas with radiation therapy and/or chemotherapy. 