infectious diseases
Chloramphenicol
Indications forChloramphenicol
Chloramphenicolhas a wide spectrum of activity against Gram-positive and gram-negative cocci and bacilli (including Overview of Anaerobic Bacteria ) Overview of Rickettsial and Related Infections , Because of bone marrow toxicity, the availability of alternative antibiotics, and the emergence of resistance,chloramphenicolis no longer a drug of choice for any infection, except for Serious infections due to a few multidrug-resistant bacteria that remain susceptible to this antibiotic Treatment because other plague drugs penetrate these spaces poorly However, whenchloramphenicolhas been used to treat meningitis caused by relatively penicillin-resistant pneumococci, outcomes have been discouraging, probably becausechloramphenicolhas poor bactericidal activity against these strains. 