hormonal and metabolic disorders
ArginineVasopressin Deficiency (Central Diabetes Insipidus)
Introduction
Argininevasopressindeficiency (central diabetes insipidus) is a lack of the hormonevasopressin(antidiuretic hormone) that causes excessive production of very dilute urine (polyuria). Argininevasopressindeficiency has several causes, including a brain tumor, a brain injury, brain surgery, tuberculosis, and some forms of other diseases. The main symptoms are excessive thirst and excessive urine production. The diagnosis is based on urine tests, blood tests, and a water deprivation test. People withargininevasopressindeficiency usually are given the medicationsvasopressinordesmopressin. (See also Overview of the Pituitary Gland .) is a hormone produced by the hypothalamus (a region of the brain that lies just above the pituitary) and stored in and released from the posterior lobe of the Overview of the Pituitary Gland . 