hepatic and biliary disorders
Hepatic Fibrosis
Treatment of Hepatic Fibrosis
Treatment of cause Because fibrosis represents a response to hepatic damage, primary treatment should focus on the cause (removing the basis of the liver injury). Such treatment may include antiviral drugs to eliminate hepatitis B virus or hepatitis C virus in chronic viral hepatitis, abstaining from alcohol in Alcohol-Related Liver Disease , weight loss in patients with Treatments aimed at reversing fibrosis are usually too toxic for long-term use (eg, corticosteroids,penicillamine) or have no proven efficacy (eg,colchicine, silymarin frommilk thistle). Other antifibrotic treatments are under study, especially for MASH (eg, glitazone,vitamin E, GLP-1 agonist, PPAR agonist, FXR agonist, caspase inhibitor, SK1 inhibitors). Coffee has been associated with a decreased risk of cirrhosis in meta-analyses, but further study is needed. 