drugs
Overview of Generic Drugs and Drug Naming
Introduction
Medications are drugs used therapeutically (that is, to treat medical conditions). Drugs often have several names. When a drug is first discovered, it is given a chemical name, which describes the atomic or molecular structure of the drug. The chemical name is usually too complex and cumbersome for general use. Next, a shorthand version of the chemical name or a code name (such as RU 486) is developed for easy reference among researchers. When a drug is approved by the Food and Drug Administration (FDA—the U.S. government agency responsible for ensuring that drugs marketed in the United States are safe and effective), it is given a Generic (official) name Brand (proprietary, trademark, or trade) name For example,phenytoinis the generic name and Dilantin is a brand name for the same drug, which is a commonly used antiseizure drug. Thegeneric nameis assigned, in the United States, by an official body—the United States Adopted Names (USAN) Council. Thebrand nameis developed by the company requesting approval for the drug and identifies it as the exclusive property of that company. When a drug is under patent protection, the company markets it under its brand name. When the drug is off patent (no longer protected by patent), the company may market its product under either the generic name or brand name. Other companies that file for approval to market the off-patent drug must use the same generic name but can create their own brand name. As a result, the same generic drug may be sold under either the generic name (for example,ibuprofen) or one of many brand names (such as Advil or Motrin). Generic and brand names must be unique to prevent one drug from being mistaken for another when drugs are prescribed and prescriptions are dispensed. To prevent this possible confusion, the FDA must agree to every proposed brand name. Government officials, doctors, researchers, and others who write about the new compound use the drug’s generic name because it refers to the drug itself, not to a particular company’s brand of the drug or a specific product. However, doctors often use the brand name on prescriptions, because it is easier to remember and doctors usually learn about new drugs by the brand name. Generic names are usually more complicated and harder to remember than brand names. Many generic names are a shorthand version of the drug’s chemical name, structure, or formula. In contrast, brand names are usually catchy, often related to the drug’s intended use, and relatively easy to remember, so that doctors will prescribe the drug and consumers will look for it by name. Brand names often suggest a characteristic of the drug. For example, Lopressor lowers blood pressure, Glucotrol controls high blood sugar (glucose) levels, and Skelaxin relaxes skeletal muscles. Sometimes, the brand name is simply a shortened version of the drug’s generic name—for example, Minocin forminocycline. when applied to such items as foods and household products, is used to describe a less expensive, sometimes less effective or lower-quality copycat version of a brand-name product. However, generic drugs, although less expensive than the comparable brand-name drug, are generally as effective and of the same quality as the brand-name drug (see Bioequivalence and Interchangeability of Generic Drugs ). In fact, generic drug makers manufacture many brand-name products for companies that control the brand names. Sometimes, more than one generic version of a drug is available. For example, many manufacturers sell versions of 