hematology and oncology
Acquired Platelet Dysfunction
Introduction
Acquired platelet dysfunction, which is common, may result fromaspirin, other nonsteroidal anti-inflammatory drugs (NSAIDs), or systemic disorders. (See also Overview of Platelet Disorders .) Acquired abnormalities of platelet function are very common. Causes include Drugs Systemic disorders Cardiopulmonary bypass Acquired platelet dysfunction is suspected and diagnosed when unusual or prolonged bleeding is observed and other possible diagnoses (eg, thrombocytopenia, coagulation abnormalities) have been eliminated. Platelet aggregation studies are unnecessary. 