genitourinary disorders
Liddle Syndrome
Introduction
Liddle syndrome is a rare hereditary disorder involving increased activity of the epithelial sodium channel (ENaC), which causes the kidneys to excrete potassium but retain too much sodium and water, leading to hypertension. Symptoms are of hypertension, fluid retention, and metabolic alkalosis. Diagnosis is through measurement of urinary electrolytes. Potassium-sparing diuretics provide the best treatment. Liddle syndrome is a rare autosomal dominant disorder of Introduction to Renal Transport Abnormalities that clinically resembles 35 years. Hypertension and symptoms and signs of Hypokalemia and 