immune disorders
Innate Immunity
Eosinophils
Eosinophils can ingest bacteria, but they also target foreign cells that are too large to ingest. Eosinophils contain granules that release enzymes and other toxic substances when foreign cells are encountered. These substances make holes in the target cell’s membranes. Eosinophils circulate in the bloodstream. However, they are less active against bacteria than are neutrophils and macrophages. One of their main functions is to attach to and thus help immobilize and kill parasites. Eosinophils may help destroy cancer cells. They also produce substances involved in inflammation and Overview of Allergic Reactions . People with allergies, parasitic infections, or asthma often have more eosinophils in the bloodstream than people without these disorders. 