blood disorders
Monocyte Disorders
MonoMAC syndrome
This rare genetic disorder, also called GATA2 deficiency affects the bone marrow, causing a very low monocyte count and also decreasing the number of certain kinds of Lymphocytes . The disorder increases the risk of infection with certain organisms, including a group of bacteria known as Symptoms vary depending on the specific microorganism that causes the infection but often involve the lungs or skin. Diagnosis is by a blood test that shows the absence of monocytes and by genetic testing. Antibiotics are given to treat infections, and a Stem Cell Transplantation may cure the disorder. Unvaccinated people should be given 