infectious diseases
Human Papillomavirus (HPV) Vaccine
Preparations of HPV Vaccine
Three vaccines protect against HPV: that protects against HPV types 6 and 11 (which cause > 90% of visible genital warts), types 16 and 18 (which cause about 70% of cervical cancers and 90% of anal cancers), and types 31, 33, 45, 52, and 58 (which together cause 10 to 20% of cervical cancers [ Preparations reference ]) A human papillomavirus quadrivalent vaccine (HPV4) that protects against types 6, 11, 16, and 18 A human papillomavirus bivalent vaccine (HPV2) that protects against types 16 and 18 Only the 9-valent vaccine is now available in the United States. Recombinant DNA technology is used to prepare HPV vaccines from the major capsid (L1) protein of HPV. The L1 proteins self-assemble into noninfectious, nononcogenic virus-like particles (VLPs). 1.National Cancer Institute: Human papillomavirus (HPV) vaccines. 2019. 