endocrine and metabolic disorders
Overview of Adrenal Function
Adrenal cortex
The adrenal cortex produces Glucocorticoids (primarilycortisol) Mineralocorticoids (primarilyaldosterone) Androgens (primarily dehydroepiandrosterone and androstenedione) Glucocorticoidspromote and inhibit gene transcription in many cells and organ systems. Prominent effects include anti-inflammatory actions and increased hepatic gluconeogenesis. Mineralocorticoidsregulate electrolyte transport across epithelial surfaces, particularly renal conservation of sodium in exchange for potassium. Adrenal androgens’chief physiologic activity occurs after conversion totestosteroneand dihydrotestosterone. The physiology of the Overview of the Endocrine System is further discussed elsewhere. 