gastrointestinal disorders
Gastrointestinal Stromal Tumors (GISTs)
Diagnosis of GISTs
Endoscopy Diagnosis of GISTs is usually by endoscopy, with biopsy and endoscopic ultrasonography for staging. Immunohistochemistry with positive staining for CD117 (C-KIT) and DOG-1 are pathognomonic for the diagnosis of GIST. Once diagnosed, all patients require complete staging with CT of the chest, abdomen, and pelvis. 