infectious diseases
Trichomoniasis
Treatment of Trichomoniasis
Oralmetronidazoleortinidazole Treatment of sex partners Women with trichomoniasis should receivemetronidazole500 mg orally twice a day for 7 days. Men should receivemetronidazole2 g orally in a single dose. An alternative treatment for women and men istinidazole2 g orally in a single dose. If infection persists in women and reinfection by sex partners has been excluded, women should be retreated withmetronidazole500 mg twice a day for 7 days ortinidazole2 g orally once a day for 7 days. Metronidazolemay cause leukopenia,disulfiram-like reactions to alcohol, or candidal superinfections. It is relatively contraindicated during early pregnancy, although it may not be dangerous to the fetus after the 1st trimester.Tinidazolehas not been established as safe during pregnancy and so is not used. Sex partners should be seen and treated for trichomoniasis with the same regimens based on sex and should be screened for other STIs. If poor adherence to follow-up by sex partners is likely, treatment can be initiated in sex partners of patients with documented trichomoniasis without confirming the diagnosis in the partner. 