neurologic disorders
Alzheimer Disease
Key Points
Although genetic factors can be involved, most cases of Alzheimer disease are sporadic, with risk predicted best by patient age. Differentiating Alzheimer disease from other causes of dementia (eg, vascular dementia, dementia with Lewy bodies) can be difficult but is often best done using clinical criteria, which are 85% accurate in establishing the diagnosis. Treat Alzheimer disease similarly to other dementias. 