kidney and urinary tract disorders
Acute Tubular Necrosis
Causes of Acute Tubular Necrosis
Acute tubular necrosis usually develops only in people who are seriously ill and in the hospital. The most common causes are An episode of Low Blood Pressure , leading to insufficient blood flowing through the kidneys Medications that damage the kidneys Serious bodywide infection ( Sepsis and Septic Shock ) leading to acute tubular necrosis are significant blood loss (due to injury or major surgery), serious Burns , serious bodywide infection ( Sepsisalso can directly damage kidney cells, which worsens the effects of the low blood pressure caused by sepsis. (an antibiotic used to treat infections that are resistant to other antibiotics), and nonsteroidal anti-inflammatory drugs (NSAIDs). Aminoglycosides are more likely to be a cause among people who are older, have had major surgery, or have severe disorders of the liver, gallbladder, or bile ducts. Rarely, exposure to a contrast agent during an imaging procedure can cause kidney damage ( Radiopaque Contrast Agents ). Acute tubular necrosis is more likely to develop in people who are older, are critically ill, or have underlying kidney disorders, diabetes, or both. 