genitourinary disorders
Immunoglobulin A Nephropathy
Symptoms and Signs of IgA Nephropathy
The most common manifestations are persistent or recurrent macroscopic hematuria or asymptomatic microscopic hematuria with mild proteinuria. Flank pain and low-grade fever may accompany acute episodes. Other symptoms are usually not prominent. Gross hematuria usually begins 1 or 2 days after a febrile mucosal (upper respiratory, sinus, enteral) illness, thus mimicking acute Postinfectious Glomerulonephritis (PIGN) , except the onset of hematuria is earlier (coinciding with or immediately after the febrile illness). When this occurs with an upper respiratory illness, it is sometimes referred to as synpharyngitic hematuria. Rapidly Progressive Glomerulonephritis (RPGN) is the initial manifestation in 