bone, joint, and muscle disorders
Paget Disease of Bone
Diagnosis of Paget Disease of Bone
X-rays Blood tests Bone scan Paget disease is often discovered accidentally when x-rays or laboratory tests are done for other reasons. Otherwise, the diagnosis of Paget disease may be suspected based on the symptoms and a physical examination. The diagnosis of Paget disease of bone can be confirmed by x-rays showing abnormalities characteristic of Paget disease and by a laboratory test to determine blood levels of alkaline phosphatase (an enzyme involved in bone formation), calcium, and phosphate. A bone scan (a Radionuclide Scanning using technetium) shows which bones are affected. 