infectious diseases
Carbapenems
Introduction
Carbapenems include Ertapenem Imipenem Meropenem Carbapenems are parenteral bactericidal beta-lactam Overview of Antibacterial Drugs that have an extremely broad spectrum. They are active against Haemophilus Infections None Overview of Anaerobic Bacteria None Most Enterobacterales (including those that produce AmpC beta-lactamase and extended-spectrum beta-lactamase [ESBL], although Proteeae Infections tends to have a higher imipenem minimum inhibitory concentration [MIC]) Methicillin-sensitive Staphylococcal Infections and Most Enterococcal Infections and many Many multidrug-resistant hospital-acquired bacteria are sensitive only to carbapenems. is used for gram-negative bacillary Acute Bacterial Meningitis ; imipenem is not used in meningitis because it may cause seizures. Most seizures occur in patients who have central nervous system abnormalities or renal insufficiency and who are given inappropriately high doses. 