children s health issues
Trisomy 13
Diagnosis of Trisomy 13
Before birth, ultrasonography of the fetus or blood tests of the mother Before birth, chorionic villus sampling, amniocentesis, or both After birth, the appearance of the infant and blood tests of the infant (See also Next-generation sequencing technologies .) Before birth,trisomy 13 may be suspected based on findings detected during an ultrasound of the fetus. Doctors also can do a test to find deoxyribonucleic acid (DNA) from the fetus in the mother's blood and use this DNA to determine an increased risk of trisomy 13. This test is called noninvasive prenatal screening (NIPS) or cell-free fetal DNA analysis. If doctors suspect trisomy 13 based on the results of these tests, they often confirm the diagnosis using Chorionic Villus Sampling , After birth,the infant's physical appearance may suggest the diagnosis of trisomy 13. To confirm the diagnosis, the infant's chromosomes are analyzed using a blood test. 