infectious diseases
Scrub Typhus
Treatment of Scrub Typhus
Doxycycline Antibiotics are most effective if given soon after symptoms begin. Primary treatment of scrub typhus isdoxycyclineuntil the patient improves, has been afebrile for 48 hours, and has received treatment for at least 7 days. is warranted ( Treatment references ), given for 5 days for mild illness and for 10 days for high-risk children. Research indicates that short courses of ( Treatment references ). Chloramphenicolis an alternative treatment. Oralchloramphenicolis not available in the United States, and its use can cause adverse hematologic effects, which requires monitoring of blood indices. 1.Centers for Disease Control and Prevention: Information for Healthcare Providers, Typhus Fevers 2.Todd SR, Dahlgren FS, Traeger MS, et al: No visible dental staining in children treated withdoxycyclinefor suspected Rocky Mountain Spotted Fever.J Pediatr166(5):1246-51, 2015. doi: 10.1016/j.jpeds.2015.02.015 3.Lee SC, Cheng YJ, Lin CH, et al: Comparative effectiveness ofazithromycinfor treating scrub typhus: A PRISMA-compliant systematic review and meta-analysis.Medicine(Baltimore) 96(36):e7992, 2017. doi: 10.1097/MD.0000000000007992 