pediatrics
PFAPA Syndrome
Treatment of PFAPA Syndrome
Sometimes glucocorticoids,colchicine,cimetidine, and/or tonsillectomy Treatment of PFAPA syndrome is optional and depends on the frequency and severity of flare-ups. , and, rarely, tonsillectomy ( Treatment reference ). Other medications such asanakinraandcanakinumabhave been tried with some success in refractory cases. Patients tend to outgrow this syndrome without sequelae. 1.Amarilyo G, Rothman D, Manthiram K, et al: Consensus treatment plans for periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome (PFAPA): a framework to evaluate treatment responses from the childhood arthritis and rheumatology research alliance (CARRA) PFAPA work group.Pediatr Rheumatol Online J18(1):31, 2020. doi: 10.1186/s12969-020-00424-x 