dermatologic disorders
Pemphigus Vulgaris
Key Points
About half of patients with pemphigus vulgaris have only oral lesions. Use Nikolsky and Asboe-Hansen signs to help clinically differentiate pemphigus vulgaris from other bullous disorders. Confirm the diagnosis by immunofluorescence testing of skin samples. Treat with systemic corticosteroids, with or without other immunosuppressive therapies (drugs, IV immune globulin, or plasma exchange). 