pediatrics
Cerebral Palsy (CP)
Identification of a cause
When history and/or brain MRI does not clearly identify a cause, laboratory tests should be done to exclude certain progressive storage disorders that involve the motor system (eg, Tay-Sachs Disease and Sandhoff Disease , Other progressive disorders (eg, infantile neuroaxonal dystrophy) may be suggested by nerve conduction studies and electromyography. These and many other brain disorders that cause CP (and other manifestations) are being increasingly identified with genetic testing (eg, microarray analysis, CP spectrum disorders gene panel, whole exome sequencing analysis), which may be done to check for a specific disorder or to screen for many disorders. 