endocrine and metabolic disorders
Syndrome of Inappropriate ADH Secretion (SIADH)
Treatment of SIADH
Treatment of cause Fluid restriction Sometimes avasopressinreceptor antagonist Sometimes hypertonic saline When SIADH is present, severe water restriction (eg, 250 to 500 mL/24 hours) is generally required. Additionally, a loop diuretic may be combined with IV 0.9% saline as in hypervolemic hyponatremia. is not widely used due to the possibility of drug-induced Acute Kidney Injury (AKI) . , a Selective vasopressin receptor antagonists , causes effective water diuresis without significant loss of electrolytes in the urine and can be used in patients who are hospitalized for treatment of resistant hyponatremia. Oral Hypertonic saline solution should be reserved for patients with severe, symptomatic hyponatremia and should be used cautiously because too-rapid correction risks complication,s such as the 