eye disorders
Overview of Uveitis
Treatment of Uveitis
Corticosteroids (usually topical) and sometimes other immunosuppressive drugs Cycloplegic-mydriatic drugs Sometimes antimicrobial drugs Sometimes surgical therapy Treatment of active inflammation usually involves corticosteroids given topically (eg,prednisoloneacetate 1% one drop as frequently as every hour while awake for severe inflammation) or by periocular or intraocular injection along with a cycloplegic-mydriatic drug (eg, homatropine 2% or 5% drops orcyclopentolate0.5% or 1.0% drops, either drug given 2 to 4 times/day depending on severity). Antimicrobial drugs are used to treat infectious uveitis. Particularly severe or chronic cases may require systemic corticosteroids or systemic noncorticosteroid immunosuppressive drugs. For example, Prednisone1 mg/kg orally once/day Systemic noncorticosteroid immunosuppressive drugs (eg,methotrexate15 to 25 mg orally once/week;mycophenolatemofetil 500 mg twice daily for 2 weeks, followed by a maintenance dose of 1 to 1.5 g orally twice daily as tolerated;adalimumab, initial dose of 80 mg, followed by 40 mg subcutaneously every 1 to 2 weeks) Infliximab5 to 10 mg/kg IV every 4 weeks Additional treatment for severe or chronic cases may require laser phototherapy, cryotherapy applied transsclerally to the retinal periphery, or surgical removal of the vitreous (vitrectomy) ( Treatment references ). 