cardiovascular disorders
Drugs for Acute Coronary Syndromes
Introduction
Treatment of Overview of Acute Coronary Syndromes (ACS) (ACS) is designed to relieve distress, interrupt thrombosis, reverse ischemia, limit infarct size, reduce cardiac workload, and prevent and treat complications. An ACS is a medical emergency; outcome is greatly influenced by rapid diagnosis and treatment. Treatment occurs simultaneously with diagnosis. Treatment includes Drugs used depend on the type of ACS and include Aspirin,clopidogrel, or both (prasugrelorticagrelorare alternatives toclopidogrelif fibrinolytic therapy has not been given) Beta-blocker Glycoprotein IIb/IIIa inhibitor considered for certain patients undergoing percutaneous coronary intervention (PCI) and high risk lesions (eg, high thrombus burden, no reflow) (particularly in Acute Myocardial Infarction (MI) [STEMI] patients at high risk of bleeding) (unless low-risk, uncomplicated Acute Myocardial Infarction (MI) ) Fibrinolytics for select patients with STEMI when timely PCI unavailable Angiotensin-converting enzyme (ACE) inhibitor (as early as possible) Statins ) are frequently added, particularly when chest pain or hypertension is present (see table Drugs for Coronary Artery Disease* ). Fibrinolytics for STEMI if primary PCI is not immediately available but worsen outcome for therapy). Nitrates is initially given sublingually, followed by continuous IV drip if needed. , to lower BP and reduce cardiac workload. Severe hypotension or other signs of Shock are ominous and must be treated aggressively with IV fluids and sometimes vasopressors. 