blood disorders
Protein Disorders Causing Bruising or Bleeding
Hypergammaglobulinemic purpura
In hypergammaglobulinemic purpura, blood vessels are damaged ( Overview of Vasculitis ) by inflammation related to high levels of immunoglobulins in the blood. This disorder primarily affects women. Recurrent crops of small, raised reddish purple discolorations develop on the lower legs. These crops leave small residual brown spots. Many people have manifestations of an underlying immune disorder, such as Doctors usually do blood tests. Often tests show that one type of immunoglobulin (called IgG) is increased. Doctors may also need to take a sample of skin for testing (biopsy). Doctors treat the underlying disorder. 