neurologic disorders
Hereditary Motor Neuropathy With Liability to Pressure Palsies (HNPP)
Key Points
Hereditary motor neuropathy with liability to pressure palsies (HNPP) is a rare, usually autosomal-dominant disorder. Consider HNPP if patients have unexplained peripheral mononeuropathies (eg, peroneal or ulnar nerve palsy, carpal tunnel syndrome) or symptoms consistent with recurrent demyelinating polyneuropathy. Diagnose using electrodiagnostic testing and genetic testing. Advise patients to avoid or modify activities that cause symptoms, and recommend wrist splints and/or elbow pads as needed. 