immunology allergic disorders
Kidney Transplantation
Introduction
Kidney transplantation is the most common type of solid organ transplantation. (See also Overview of Transplantation .) Theprimary indicationfor kidney transplantation is Chronic Kidney Disease None Absolute contraindicationsinclude Comorbidities that could compromise graft survival (eg, severe heart disorders, cancer), which can be detected via thorough screening Relative contraindicationsinclude Poorly controlled diabetes, which can lead to rapid failure of the allograft Patients in their 70s and sometimes 80s may be candidates for transplants if they are otherwise healthy and functionally independent with good social support, if they have a reasonably long life expectancy, and if transplantation is likely to substantially improve function and quality of life beyond simply freeing them from dialysis. Patients with type 1 diabetes may be candidates for simultaneous pancreas-kidney or pancreas-after-kidney transplantation (see also Pancreas Transplantation ). 