neurologic disorders
Subacute and Chronic Meningitis
Chronic meningitis in patients with HIV infection
Meningitis is common among HIV-infected patients. Most CSF abnormalities result from HIV, which invades the CNS early in the infection. Onset of meningitis and meningeal symptoms often coincides with seroconversion. Meningitis may then remit or follow a steady or fluctuating course. However, many other organisms can cause chronic meningitis in patients with HIV infection. They includeC. neoformans(the most common),M. tuberculosis,Treponema pallidum,Toxoplasma gondii, andCoccidioides immitisin endemic areas. CNS lymphoma can also cause symptoms and signs similar to those of meningitis in patients with HIV infection. Regardless of the cause, parenchymal lesions may develop. 