neurologic disorders
Huntington Disease
Introduction
Huntington disease is an autosomal dominant disorder characterized by chorea, neuropsychiatric symptoms, and progressive cognitive deterioration, usually beginning during middle age. Diagnosis is by genetic testing. First-degree relatives should be offered genetic counseling before genetic tests are done. Treatment is supportive. (See also Overview of Movement and Cerebellar Disorders .) Huntington disease affects both sexes equally. 