pediatrics
Erythema Infectiosum (Parvovirus B19 Infection)
Pathophysiology of Erythema Infectiosum
Parvovirus B19 is a single-stranded DNA virus that causes transient suppression of erythropoiesis that is mild and asymptomatic except in children with underlying Overview of Hemoglobinopathies (eg, Erythema infectiosum can be transmitted transplacentally, sometimes resulting in Spontaneous Abortion , The risk of fetal death is approximately 2 to 6% after maternal infection, with risk greatest during the first half of pregnancy ( Pathophysiology reference ). 1.Enders M, Weidner A, Zoellner I, et al: Fetal morbidity and mortality after acute human parvovirus B19 infection in pregnancy: Prospective evaluation of 1018 cases.Prenat Diagn24(7):513–518, 2004. doi: 10.1002/pd.940 