cardiovascular disorders
Early Repolarization Syndrome
Diagnosis of Early Repolarization Syndrome
Characteristic clinical and ECG manifestations Clinical screening of first-degree family members Diagnosis should be considered in patients who have had polymorphic ventricular tachycardia, ventricular fibrillation, or sudden cardiac arrest (or a family history of those events in the absence of structural heart disease) and who also have ECG changes showing an inferior and/or lateral early repolarization pattern. The typical ECG finding of early repolarization is J-point elevation of≥1 mm (≥0.1 mV) followed by ST segment elevation in two or more contiguous inferior and/or lateral leads. Because specific gene defects are seldom identified, genetic testing is not typically recommended for patients or family members. However, first-degree family members should be evaluated clinically and with an ECG. 