psychiatric disorders
Bipolar Disorders
Etiology of Bipolar Disorders
The exact cause of bipolar disorder is unknown. Heredity plays a significant role ( Etiology reference ). There is also evidence of dysregulation of the neurotransmitters Psychosocial factors may be involved. Stressful life events are often associated with initial development of symptoms and later exacerbations, although cause and effect have not been established. Certain medications and substances can trigger exacerbations in some patients with bipolar disorder; these include Sympathomimetics (eg, Cocaine , Alcohol Toxicity and Withdrawal None Corticosteroids Certain Medications for Treatment of Depression (eg, tricyclics, noradrenergic reuptake inhibitors) 1.Gordovez FJA, McMahon FJ: The genetics of bipolar disorder.Mol Psychiatry25(3):544-559, 2020. doi: 10.1038/s41380-019-0634-7 