infections
Macrolides
Use of Macrolides During Pregnancy and Breastfeeding
Macrolides should be taken during pregnancy only when the benefits of treatment outweigh the risks. Witherythromycinandazithromycin, no harmful effects on the fetus have been observed in animal studies, but no well-designed studies have been done in pregnant women.Erythromycinis considered among the safest antibiotics to use during pregnancy. It is considered safer thanazithromycinbecause it has been used more, and thus more is known about it. except when there is no alternative drug. (See also Safety of Medications During Pregnancy .) during breastfeeding is generally considered acceptable. Whether other macrolides are safe to use during breastfeeding is unknown. (See also Medication and Substance Use During Breastfeeding .) 