dermatologic disorders
Pityriasis Rubra Pilaris
Treatment of Pityriasis Rubra Pilaris
Symptom relief (eg, with emollients, topical lactic acid and topical corticosteroids, or oral retinoids) Sometimes systemic therapy (eg, oralacitretin,methotrexate, biologics) Treatment of pityriasis rubra pilaris is exceedingly difficult and empiric. The disorder may be ameliorated but almost never cured; classic forms of the disorder resolve slowly over 3 years, whereas nonclassic forms persist. Scaling may be reduced with emollients or 12% lactic acid under occlusive dressing, followed by topical corticosteroids. (IL-17 inhibitor) are being used increasingly based on limited observational data suggesting benefit and on indirect evidence of their efficacy for the treatment of psoriasis ( Treatment references , , and systemic corticosteroids have also been used ( Treatment references ). 1.Eastham AB, Femia A, Qureshi A, et al: Treatment options for pityriasis rubra pilaris including biologic agents: A retrospective analysis from an academic medical center.JAMA Dermatol150(1):92–94, 2014. doi: 10.1001/jamadermatol.2013.4773 2.Napolitano M, Abeni D, Didona B: Biologics for pityriasis rubra pilaris treatment: A review of the literature.J Am Acad Dermatol79(2):353–359.e11, 2018. doi: 10.1016/j.jaad.2018.03.036 3.Engelmann C, Elsner P, Miguel D: Treatment of pityriasis rubra pilaris type I: A systematic review.Eur J Dermatol29(5):524-537, 2019. doi: 10.1684/ejd.2019.3641 