infectious diseases
Polypeptide Antibiotics: Bacitracin, Colistin, Polymyxin B
Use During Pregnancy and Breastfeeding
Bacitracinmay pose minimal risk during pregnancy and breastfeeding because systemic absorption is minimal; however, safety has not been established. Polymyxin Bhas not been adequately evaluated in animal reproduction studies. No well-controlled studies have been done in pregnant women. Safety ofpolymyxin Bin pregnant women has not been determined. Colistin methane sulfonate(CMS) showed some risk in animal reproduction studies. Data related to pregnancy in humans are inadequate. Whether it is safe to use colistin or CMS during breastfeeding is unknown. 