pediatrics
Down Syndrome (Trisomy 21)
Treatment of Down Syndrome
Screening for complications and associated diseases Treatment of specific manifestations Genetic counseling The underlying genetic abnormality cannot be cured. Management depends on specific manifestations, and surveillance for complications or associated diseases is fairly uniform for all children (see Concomitant medical conditions ). Some congenital cardiac or gastrointestinal anomalies are repaired surgically. Other diseases (eg, hypothyroidism, celiac disease, leukemia) are treated as appropriate. Care of children with Down syndrome and their families should also include genetic counseling for the family, social support, and educational programming appropriate for the level of intellectual functioning (see Intellectual Disability ). 