endocrine and metabolic disorders
Medications for Diabetes Mellitus Treatment
Adjunctive Medications for Diabetes
Pharmacologic measures to prevent or treat Complications of Diabetes Mellitus ( Angiotensin-converting enzyme (ACE) inhibitors orangiotensin IIreceptor blockers (ARBs) Aspirin Statins are indicated for patients with evidence of early Diabetic Nephropathy (albuminuria), even in the absence of hypertension, and are a good choice for treating hypertension in patients who have diabetes mellitus and who have not yet shown renal impairment. ACE inhibitors prevent cardiovascular events in patients with diabetes mellitus. Treatment with an ACE inhibitor or ARB is recommended in patients with known atherosclerotic cardiovascular disease (ASCVD) for secondary prevention. might be considered for primary prevention in patients with diabetes who are ≥ 50 years of age and have at least one additional Risk Factors and are not at increased risk of bleeding. In patients > 70 years, risk of bleeding may outweigh benefits of primary prevention. are recommended for all patients with diabetes 40 to 75 years of age ( Adjunctive medications references ). Moderate- to high-intensity treatment is used, and a high-intensity statin ( 1.Fox CS, Golden SH, Anderson C, et al: AHA/ ADA Scientific Statement: Update on prevention of cardiovascular disease in adults with type 2 diabetes mellitus in light of recent evidence.Circulation132: 691–718, 2015. 2.Garber AJ, Handelsman Y, Grunberger G, et al: Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm--2020 executive summary.Endocrine Practice26:107–139, 2020. 3.Grundy SM, Stone NJ, Bailey AL, et al: 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.J Am Coll Cardiol73(24):3168–3209, 2019. doi: 10.1016/j.jacc.2018.11.002 4.American Diabetes Association: Standards of Medical Care in DiabetesDiabetes Care46 (Supplement 1): 1-291, 2023. 