gastrointestinal disorders
Overview of Gastritis
Introduction
), drugs (nonsteroidal anti-inflammatory drugs, alcohol), stress, and autoimmune phenomena (atrophic gastritis). Many cases are asymptomatic, but Dyspepsia and Gastritis can be classified in several ways: By severity of mucosal injury, as Erosive Gastritis or By the site of involvement (ie, cardia, body, antrum) Histologically as acute or chronic (based on the inflammatory cell type) No classification scheme matches perfectly with the pathophysiology; a large degree of overlap exists. Some forms of gastritis involve acid peptic disease and Helicobacter pylori Infection (see also Acute gastritisis characterized by polymorphonuclear leukocyte infiltration of the mucosa of the antrum and body. Chronic gastritisimplies some degree of atrophy (with loss of function of the mucosa) or metaplasia. It predominantly involves the antrum (with subsequent loss of G cells and decreased gastrin secretion) or the corpus (with loss of oxyntic glands, leading to reduced acid, pepsin, and intrinsic factor). 