dermatologic disorders
Pyoderma Gangrenosum
Treatment of Pyoderma Gangrenosum
Wound care Corticosteroids Tumor necrosis factor (TNF)-alpha inhibitors Sometimes other anti-inflammatory drugs or immunosuppressants Avoidance of surgical debridement Wound healing can be promoted with moisture-retaining occlusive dressings for less exudative plaques and absorptive dressings for highly exudative plaques. Biologic and other specialized dressings may be needed in refractory cases. Wet-to-dry dressings should be avoided. Topical therapy with high-potency corticosteroids ortacrolimuscan help with superficial and early lesions. ) are effective, particularly in patients who have Overview of Inflammatory Bowel Disease . Surgical treatments are avoided because of the risk of wound extension ( Treatment reference ). 1.Alavi A, French LE, Davis MD, et al:Pyoderma gangrenosum: An update on pathophysiology, diagnosis and treatment.Am J Clin Dermatol18(3):355–372, 2017. doi: 10.1007/s40257-017-0251-7 