children s health issues
Congenital Myopathies
Central core myopathy and multiminicore myopathy (core myopathies)
Central core myopathy and multiminicore myopathy are the most common forms of congenital myopathy. Most affected newborns have severely reduced muscle tone (hypotonia, or "floppiness") and mild Weakness , but sometimes symptoms of core myopathy do not manifest until adulthood. Many people also have facial weakness. The weakness does not become worse, and life expectancy is normal, but some people are severely affected and require a wheelchair. People who have central core myopathy are at increased risk of a life-threatening disorder of elevated body temperature called Malignant Hyperthermia . 