injuries poisoning
Serotonin Syndrome
Introduction
Serotonin syndrome is a potentially life-threatening condition resulting from increased central nervous system serotonergic activity that is usually drug related. Symptoms may include mental status changes, hyperthermia, and autonomic and neuromuscular hyperactivity. Diagnosis is clinical. Treatment is supportive. Serotonin syndrome can occur with therapeutic drug use, self-poisoning, or, most commonly, unintended drug interactions when 2 serotonergic drugs are used (see table). It can occur in all age groups. in severe serotonin syndrome can include Metabolic Acidosis , (See also Overview of Heat Illness .) 