infectious diseases
Toxic Shock Syndrome (TSS)
Symptoms and Signs of Toxic Shock Syndrome
Onset of toxic shock syndrome is sudden, with Fever (39 to 40.5° C, which remains elevated) Hypotension (which can be refractory) A diffuse macular erythroderma Involvement of at least 2 other organ systems Staphylococcal TSSis likely to cause vomiting, diarrhea, myalgia, elevated creatine kinase, mucositis, hepatic damage, thrombocytopenia, and confusion. The staphylococcal TSS rash is more likely to desquamate, particularly on the palms and soles, between 3 and 7 days after onset. Streptococcal TSScommonly causes acute respiratory distress syndrome (in about 55% of patients), coagulopathy, and hepatic damage and is more likely to cause high fever, malaise, tachycardia, tachypnea, and, at the site of a soft-tissue infection, severe pain. Renal impairment is frequent and common in both types of TSS. TSS may progress within 48 hours to syncope, tissue necrosis, shock, disseminated coagulation, multisystem organ failure, and death. Less severe cases of staphylococcal TSS are fairly common. 