dermatologic disorders
Epidermolysis Bullosa
Prognosis for Epidermolysis Bullosa
Severe junctional epidermolysis bullosa and dystrophic epidermolysis bullosa cause significant mortality before age 2 years. Generalized severe epidermolysis bullosa also can be fatal. Death occurs after complications such as infection, malnutrition, and dehydration. Blistering tends to lessen with age. Patients with junctional epidermolysis bullosa, dystrophic epidermolysis bullosa, and Kindler syndrome may develop squamous cell carcinomas of skin and mucosal membranes in adulthood. Chronic disease can be debilitating and life-altering. However, some serious symptoms can lessen over time as somatic growth re-expands internal lumina that were stenosed by previous scarring. 