hematology and oncology
Monocytopenia
Monocytopenia due to GATA2 mutation
 ( Monocytopenia reference ). Dendritic cells are decreased, and there may also be Despite near-absence of circulating monocytes, tissue macrophages are usually preserved. Also, immunoglobulin levels are usually normal even when circulating B cells are depressed. The bone marrow is hypocellular and can show fibrosis and multilineage dysplasia. Karyotypic abnormalities, including monosomy 7 and trisomy 8, may be present. complex (MAC) or other nontuberculous mycobacterial infections are common (MonoMAC syndrome). Fungal infections (ie, Histoplasmosis , Unvaccinated patients should be given Human Papillomavirus (HPV) Vaccine . Any infections are treated with appropriate antimicrobials. Allogeneic 