nutritional disorders
Vitamin A Toxicity
Key Points
Vitamin Atoxicity can be caused by ingesting high doses ofvitamin A—acutely (usually accidentally by children) or chronically (eg, as megavitamin therapy or treatment for skin disorders). Acute toxicity causes rash, abdominal pain, increased intracranial pressure, and vomiting. Chronic toxicity causes rash, increased intracranial pressure, sparse and coarse hair, dry and rough skin, and arthralgia; risk of fractures is increased, especially in the older people. Diagnose based on clinical findings. Whenvitamin Ais stopped, symptoms (except birth defects) usually resolve within 1 to 4 weeks. 