drugs
Drug Administration
Rectal route
Many drugs that are administered orally can also be administered rectally as a suppository. In this form, a drug is mixed with a waxy substance that dissolves or liquefies after it is inserted into the rectum. Because the rectum’s wall is thin and its blood supply rich, the drug is readily absorbed. A suppository is prescribed for people who cannot take a drug orally because they have nausea, cannot swallow, or have restrictions on eating, as is required before and after many surgical operations. Drugs that can be administered rectally includeacetaminophen(for fever),diazepam(for seizures), and laxatives (for constipation). Drugs that are irritating in suppository form may have to be given by injection. 