eye disorders
Cogan Syndrome
Symptoms and Signs of Cogan Syndrome
The presenting symptoms involve the ocular system in 38% of patients, the vestibuloauditory system in 46%, and both in 15%. By 5 months, 75% of patients have both ocular and vestibuloauditory symptoms. Nonspecific systemic complaints include fever, headache, joint pain, and myalgia. Ocular involvement includes any combination of the following: Bilateral Interstitial Keratitis or other corneal stromal keratitis Episcleritis or Overview of Uveitis None Papillitis Other orbital inflammation (eg, vitritis, choroiditis) Ocular symptoms include irritation, pain, photophobia, and decreased vision. Ocular examination shows a patchy corneal stromal infiltrate typical of Interstitial Keratitis , ocular redness, optic nerve edema, proptosis, or a combination of these symptoms. Vestibuloauditory symptoms can include Pathophysiology , A diastolic heart murmur may be present when aortitis is significant. Claudication may be present if limb vessels are affected. 