nutritional disorders
Thiamin Deficiency
Key Points
The risk of thiamin deficiency is increased in people who subsist on highly refined carbohydrates such as polished rice and white flour (as occurs in countries with high rates of food insecurity) or people with alcohol use disorder. Early findings can be nonspecific; peripheral neurologic deficits, high-output heart failure, and Wernicke-Korsakoff syndrome (mainly in people with alcohol use disorder) may also develop. Diagnose based on clinical findings, including a favorable response to treatment with supplemental thiamin. 