endocrine and metabolic disorders
Hypermagnesemia
Treatment of Hypermagnesemia
Calcium gluconate Diuresis or dialysis Treatment of severe magnesium toxicity (eg, 12 mg/dL [5.0 mmol/L]) consists of circulatory and respiratory support and administration of 10%calcium gluconate10 to 20 mL IV.Calcium gluconatemay temporarily reverse many of the magnesium-induced changes, including respiratory depression. Administration of IVfurosemidecan increase magnesium excretion when renal function is adequate; volume status should be maintained. Hemodialysis may be valuable in severe hypermagnesemia, because a relatively large fraction (about 70%) of blood magnesium is not protein bound and thus is removable with hemodialysis. When hemodynamic compromise occurs and hemodialysis is impractical, 