neurologic disorders
Stiff Person Syndrome
Treatment of Stiff Person Syndrome
Diazepamorbaclofen IV immune globulin (IVIG) Sometimesrituximabor plasma exchange. Symptomatic therapy is available for stiff-person syndrome.Diazepamis the drug of choice; it most consistently relieves muscle stiffness. Ifdiazepamis ineffective,baclofen, given orally or intrathecally, can be considered. Corticosteroids are reportedly effective but have many long-term adverse effects. or Plasma exchange may be suggested. 