cardiovascular disorders
Varicose Veins
Etiology of Varicose Veins
Etiology is usually unknown, but varicose veins may result from primary venous valvular insufficiency with reflux or from primary dilation of the vein wall due to structural weakness. In some people, varicose veins result from chronic venous insufficiency and venous hypertension. Most people have no obvious risk factors. Varicose veins are common within families, suggesting a genetic component. Varicose veins are more common among women becauseestrogenaffects venous structure, pregnancy increases pelvic and leg venous pressures, or both. Rarely, varicose veins are part of Klippel-Trénaunay-Weber syndrome, which includes congenital Arteriovenous Fistula and diffuse cutaneous capillary angiomas. 