immunology allergic disorders
DiGeorge Syndrome
Treatment of DiGeorge Syndrome
Partial syndrome: Calcium andvitamin Dsupplementation Complete syndrome: Transplantation of cultured thymus tissue or hematopoietic stem cells In partial DiGeorge syndrome, hypoparathyroidism is treated with calcium andvitamin Dsupplementation; long-term survival is not affected. Complete DiGeorge syndrome is fatal without treatment, which is transplantation of cultured thymus tissue or Hematopoietic Stem Cell Transplantation . A review of thymus transplantation has shown relatively good results with T cell reconstitution by 5 to 6 months ( 1.Davies EG, Cheung M, Gilmour K, et al: Thymus transplantation for complete DiGeorge syndrome: European experience.J Allergy Clin Immunol140: 1660–1670.e16, 2017. 