musculoskeletal and connective tissue disorders
Eosinophilic Granulomatosis with Polyangiitis (EGPA)
Etiology of EGPA
The cause of eosinophilic granulomatosis with polyangiitis is unknown. However, an allergic mechanism, with tissue directly injured by eosinophils and neutrophil degranulation products, may be involved. Activation of T lymphocytes seems to help maintain eosinophilic inflammation. The syndrome occurs in patients who have adult-onset Asthma , 