pediatrics
Mumps
Key Points
Mumps causes painful enlargement of the salivary glands, most commonly the parotids. Cases may occur in vaccinated people because of primary vaccination failure or waning immunity. Approximately 30% of unvaccinated and 6% of vaccinated infected postpubertal males develop orchitis, usually unilateral; some testicular atrophy may occur, buttestosteroneproduction and fertility are usually preserved. Other complications include meningoencephalitis and pancreatitis. Laboratory diagnosis is done mainly for public health purposes and when disease manifestations are atypical, such as absence of parotitis, unilateral or recurrent parotitis, parotitis in previously immunized patients, or prominent involvement of tissues other than the salivary glands. Universal vaccination is imperative unless contraindicated (eg, by pregnancy or severe immunosuppression). 