special subjects
Dehydroepiandrosterone (DHEA)
Drug Interactions
DHEA may increase bleeding in people taking anticoagulants. DHEA has triggered mania in people taking antidepressants. DHEA may antagonize the anti-estrogenic effects oftamoxifen, aromatase inhibitors (such asanastrozole), andfulvestrant. DHEA may increase the concentrations of the benzodiazepinetriazolam, and decrease the effectiveness of bacillus Calmette-Guérin (BCG) vaccination for tuberculosis. (See also table.) 