children s health issues
Ehlers Danlos Syndromes
Introduction
Ehlers-Danlos syndromes are rare hereditary disorders of connective tissue that result in unusually flexible joints, very elastic skin, and fragile tissues. These syndromes are caused by a defect in one of several genes that control the production of connective tissue. Typical symptoms include flexible joints, a humpback, flat feet, and elastic skin. The diagnosis is based on symptoms and results of a physical examination. Most people with this syndrome have a normal life span. There is no cure for Ehlers-Danlos syndromes. Ehlers-Danlos syndromes are caused by an abnormality in one of the genes that controls the production of connective tissue. Overview of Connective Tissue Disorders in Children is the tough, often fibrous tissue that binds the body's structures together and provides support and elasticity. There are 6 major types of Ehlers-Danlos syndrome and 7 less common types. They involve different genes and vary widely in severity. Although the types have slightly different symptoms, they all result in abnormally fragile connective tissue, which causes problems in joints and bones and may weaken internal organs. 