infections
Amebic Brain Infection: Granulomatous Amebic Encephalitis
Treatment of Granulomatous Amebic Encephalitis
A combination of medications Granulomatous amebic encephalitis and any skin sores are typically treated with a combination of medications including Miltefosine and one or more of the following: Pentamidine(typically used to treat fungal infections—an antifungal medication—or protozoal infections) Sulfadiazineortrimethoprim/sulfamethoxazole (antibiotics) Flucytosine(an antifungal medication) Fluconazoleor the related medicationsvoriconazoleoritraconazole(antifungal medications) Amphotericin B(an antifungal medication) Azithromycinorclarithromycin(antibiotics) Some of these medications are taken by mouth, and others are given by injection. Some can be given in more than one way. Althoughmiltefosinecan cause birth defects in pregnant women, doctors often use it anyway because granulomatous amebic encephalitis is usually fatal without treatment, so the potential benefits of therapy outweigh the risk. Women of childbearing age who are taking this medication must use effective birth control measures. Sometimes surgery is also needed. Skin sores, if present, are cleaned. 