gastrointestinal disorders
Lynch Syndrome
Treatment of Lynch Syndrome
Surgical resection The surgical management of Lynch syndrome is based on the predicted lifetime risk of a second colon cancer arising in the same patient at a later date (metachronous disease). In younger adults, total abdominal colectomy with an ileorectal anastomosis and surveillance of the rectum is often offered. A reasonable alternative is removal of only the part of the colon with the primary tumor (segmental colectomy) with close endoscopic surveillance of the remainder. Often this alternative is used in older adults or in patients with comorbidities that make surgery high risk ( Treatment reference ). 1.Giardiello FM, Allen JI, Axilbund JE, et al: Guidelines on genetic evaluation and management of Lynch syndrome: A consensus statement by the US Multi-society Task Force on colorectal cancer.Am J Gastroenterol109(8):1159–1179, 2014. doi: 10.1038/ajg.2014.186 