dermatologic disorders
Lichen Planus
Etiology of Lichen Planus
Lichen planus (LP) is thought to be caused by a T cell–mediated autoimmune reaction against basal epithelial keratinocytes in people with genetic predisposition. Medications (especially beta-blockers, nonsteroidal anti-inflammatory drugs [NSAIDs], angiotensin-converting enzyme inhibitors, sulfonylureas, gold, antimalarials,penicillamine, and thiazides) can cause LP; drug-induced LP (sometimes called lichenoid drug eruption) may be indistinguishable from nondrug-induced LP or may have a pattern that is more eczematous. Associations of oral lichen planus with hepatitis ( Hepatitis B, Acute , 