 It could look similar to a body tissue like, for example, your knuckles and joints. It could be a source of how rheumatoid arthritis. And if you have a genetic predisposition toward a weakness and you have the leaky gut, you've got a multitude of combinations of things that can lead to a problem. Or whether it's a thyroid issue. There's thyroid autoimmune, whether it's Graves or Hashimoto's.