 It means that he doesn't care for the Messiah, that the desire of woman is kind of a title that the Jewish mothers used to speak of Messiah. In other words, the ultimate desire of a Jewish woman would be to give birth to the Messiah. But I really believe that interpretation is foreign to the context here. Why should we introduce into this some Jewish element? We cannot distinguish Antichrist because he has no desire for the Messiah. A lot of people don't have that.