 bunch of different medication cycles, bunch of different types of treatments. We were finding, based off of the results, that ketamine was really helping that kind of person, the person who had lost all hope because they had tried whatever was available, at least from a psychiatric standpoint. So this is a real game changer in the most optimistic view. You explained how ketamine actually has a physical change on some elements of our brain chemistry. What do you observe in terms of personality changes that it might bring to an individual who's using ketamine to treat their depression?