 On Wall Street Wednesday, the Dow gained 429 points. The S&P 500 rallied 1% and closed above 5,600. Jeff Claybaugh, WTOP News. Asia-Pacific markets are all higher tonight. Hong Kong's Hang Seng, for example, up 1%. We've got an interesting perspective coming next on vaccines and what we may have to do as a country the next time that there's a pandemic.