 Your family's lives are at stake. What? Despicable Me 4 led the way over the holiday weekend with $75 million in ticket sales from Friday to Sunday. But Universal Studios says it really raked in close to $123 million since opening Wednesday. I'm anxiety. It beat the biggest movie of the year so far, Inside Out 2, which came in second with another $30 million. A Quiet Place Day 1 was third with $21 million. Monica Ricks, CBS News.