 Mornings were made for better things than rheumatoid arthritis or RA. Zeljanz Tofacitinib is a pill for adults with moderate to severe RA when tumor necrosis factor blockers did not work well or could not be tolerated. Zeljanz can help relieve joint pain, swelling, and help stop further joint damage. Zeljanz can lower your ability to fight infections. Don't start if you have one. Before and during treatment, your doctor should check for infections like TB and do blood tests.