 I have never endorsed a weight loss product because most don't deliver until now. Science behind Calicurb is so compelling that I can support it as a plausible alternative for curbing appetite and enhancing satiety to help you shed pounds. The active ingredient in Calicurb, Amerisate, comes from a specific New Zealand-grown hops flower which works by activating your body's own appetite-regulating chemical messengers, including GLP-1.