 Let's start with the Sackler family, which in the US are widely blamed for much of the opioid crisis there, which kills tens of thousands of Americans through overdoses each year. The family owned and operated Purdue Pharma, the OxyContin maker, for decades. And when the company was wound up, the Sacklers agreed to pay $6 billion towards a wider settlement in exchange for sweeping protections against civil claims related to the addictive opioid.