 Yeah, so the rates of young onset colorectal cancer, so colorectal cancer in people under the age of 50, have increased by about 2% per year since the mid-1990s. And cancer deaths in these young people have now also started to rise. And this is very different from a few years ago. This increase follows a birth cohort effect where the change is varied by generation. So a person born in 1990 now has quadrupled the risk of developing rectal cancer compared to a person born in 1950.