IO therapies have become the backbone of many cancer regimens.
In addition to targeting mutations and epigenetic changes in cancer, we are pioneering approaches to develop the next wave of immuno-oncology (IO) medicines. IO therapies can spur recognition of the presence of cancer that the human body’s own immune surveillance mechanisms may have missed, and can overcome the immunosuppressive mechanisms that cancers frequently develop as they evolve6,7. IO therapies have become the backbone of many cancer regimens.