Also, if your dough sheet starts to get too long to handle, just cut it in half with a knife.
Using your hands, shape the dough wedge into a oval-shaped flat disc. Feed the dough through the pasta maker on the widest setting. (On my pasta maker, this is setting number 1.)  Once the sheet comes out, fold it into thirds, similar to how you would fold a piece of paper to fit in an envelope. Feed it through the rollers 2 or 3 more times, still on the widest setting. Then continue to feed the dough through the rollers as you gradually reduce the settings, one pass at a time, until the pasta reaches your desired thickness. (I like setting 6 on my pasta maker.)  Whenever the dough starts to get a bit sticky as you pass it through the rollers, just pause and drape the dough onto the floured cutting board to re-flour, being sure to coat both sides of the dough. Also, if your dough sheet starts to get too long to handle, just cut it in half with a knife.