Plants have the capability for the production of different bioactive compounds, but a huge amount of botanical materials is necessary to obtain a small amount of the target substances (Gómez and Luiz, 2018).
The plant kingdom constitutes 300,000–400,000 higher plant species (which is likely to increase) and is always an important source of novel potential chemical entities for active pharmaceutical ingredients and agricultural importance. Despite the present focus on synthetic entities to develop potential drugs, the importance of medicinal plants in various disease managements is still enormous (Rao and Satish, 2016). Medicinal plants are an important source for natural products which are used to treat several diseases; hence, they are the main basis for novel drug discovery. Plants have the capability for the production of different bioactive compounds, but a huge amount of botanical materials is necessary to obtain a small amount of the target substances (Gómez and Luiz, 2018). These days some medicinal plants are becoming rather scarce. Indeed, it is very important to point out the interactions between endophytic microbes and host plants, because endophytic microorganisms can produce highly diverse potent compounds, including those from host plants which have significant biological activities (Kusari and Spiteller, 2011).