The technology is open to licensing and co-development partnerships.
At UT Health San Antonio, scientists have developed a new strain of mice with a human immune system by utilizing human CD34+ stem cells from umbilical cord blood. By administering β-Estradiol (a female sex hormone), they achieved up to 95% human cell engraftment, leading to a fully functional human immune system. This development enables rapid antibody generation, supports human-specific pathogen studies, and enhances drug screening. It has potential to advance preclinical research and offers new insights into diseases previously hindered by inadequate models. The technology is open to licensing and co-development partnerships.