Foodies should time their stay with the bustling farmers market (Thursday from 6 to 9 p.m.), where more than 100 vendors purvey a bounty of farm-fresh produce, flowers and even farm-to-table dinners.
The unpretentious downtown area is studded with historic landmarks, including the 18th-century San Luis Obispo de Tolosa Mission, now a museum housing artifacts from Native American and Mission-era history. Foodies should time their stay with the bustling farmers market (Thursday from 6 to 9 p.m.), where more than 100 vendors purvey a bounty of farm-fresh produce, flowers and even farm-to-table dinners.