You’re talking about a specific occasion?  Or are you just talking about her general struggles?  What is her perspective on her feelings?  What about your perspective?
assitant
Oh. That’s unfortunate. I’m sorry to hear about it. I’m sorry to hear that she’s sad about this. Maybe you could send her a message to let her know you’re thinking of her?  Here’s the web address of my “I’m thinking of you” website.  You could try writing her a note.  Have you
assistant
How can I comfort my wife during the holidays when she gets down?
user
Your wife’s been having a rough time?  Maybe you could tell her how you see her?  Or write her a note?
assistant
She has a rough time during the holidays.
user