question: What is the chromosomal location of the LDL receptor gene associated with autosomal dominant Familial Hypercholesterolemia?
answer: Familial hypercholesterolemia (FH) is an autosomal dominant inherited metabolic disorder resulting in advanced vascular atherosclerosis and premature death, primarily from coronary artery disease. The primary defect is a mutation in the gene encoding for the plasma LDL receptor located on the short arm of chromosome 19