32. 委员会仍然认为，机械信息对于委员会判断低于大约 0.2 Gy 的剂量的辐射所造成的健康影响非常重要。但是，如要确定与健康有关的某一特定生物效应的形成机制，有关数据需要独立再现，而且这些数据需要与所审查的特定疾病表现出很强的一致性。在这方面，据认为，委员会 2000 年报告所审查的关于细胞核微剂量学能量分布和细胞随后对直接造成的 DNA 损伤进行处理的数据为判断对风险估计造成影响的机制提供了一个适当的基础。但委员会认识到，许多机械过程都将有助于产生辐射引发的健康影响。
32. The Committee continues to hold the view that mechanistic information is important for its judgements on radiation-induced health effects at doses below about 0.2 Gy. However, to ascribe a mechanism for the development of a particular health-related biological effect, the data in question need to be independently replicated and to show strong coherence with the particular disease considered. In this respect, the data on microdosimetric energy distribution in the cell nucleus and the subsequent cellular processing of directly induced DNA damage, reviewed in the Committee’s 2000 report, are considered to provide a suitable foundation for judgements on mechanisms that affect risk estimation. However, the Committee recognizes that a variety of mechanistic processes will contribute to the development of radiation-induced health effects.