 在国家一级，美国采取措施，以实施所有两百多项安理会第 1540号决议的义务和建议。美国在 2013 年向 1540 委员会提交了报告，说明美国所做的这些努力，包括与核不扩散有关的措施，在 2014年向委员会提交了一系列国家有效做法的报告，包括那些旨在打击核扩散的做法。
 Nationally, the United States has taken measures to implement all of the more than two hundred UNSCR 1540 obligations and recommendations. The United States in 2013 provided the 1540 Committee with a report on these efforts including measures related to nuclear non-proliferation, and in 2014 submitted to the Committee a set of national effective practices, including those practices designed to combat nuclear proliferation.