when was the first hepatitis b vaccine given
Hepatitis B vaccine The first hepatitis B vaccine was approved in the United States in 1981.[3] A recombinant version came to market in 1986.[1] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[4] As of 2014, the wholesale cost in the developing world is US$0.58–13.20 per dose.[5] In the United States it costs US$50–100.[6]