most serious toxic effect of acute acetaminophen overdose
Paracetamol poisoning Paracetamol poisoning, also known as acetaminophen poisoning, is caused by excessive use of the medication paracetamol (acetaminophen).[3] Most people have few or non-specific symptoms in the first 24Â hours following overdose.[1] This may include feeling tired, abdominal pain, or nausea.[1] This is typically followed by a couple of days without any symptoms after which yellowish skin, blood clotting problems, and confusion occurs.[1] Additional complications may include kidney failure, pancreatitis, low blood sugar, and lactic acidosis.[1] If death does not occur, people tend to recover fully over a couple of weeks.[1] Without treatment some cases will resolve while others will result in death.[1]