who plays sheldons sister on big bang theory
Laurie Metcalf Laura Elizabeth "Laurie" Metcalf[1] (born June 16, 1955) is an American actress. She is known for her television roles as Jackie Harris on the ABC sitcom Roseanne (1988–97); Carolyn Bigsby on Desperate Housewives (2006); the recurring role of Mary Cooper on The Big Bang Theory (2007–present); Dr. Jenna James on Getting On (2013–15),[2] and Marjorie McCarthy in The McCarthys (2014–15).[3] She voiced the role of Mrs. Davis in the Toy Story film series. Her other film appearances include Making Mr. Right (1987), JFK (1991), Mistress (1992), and as Debbie Salt / Mrs. Loomis in Scream 2 (1997). She has also appeared in commercials for Plan USA, a humanitarian organization which helps children in need around the world.[4]