which phase of healing begins about 3 weeks after injury
Wound healing When the levels of collagen production and degradation equalize, the maturation phase of tissue repair is said to have begun.[20] During maturation, type III collagen, which is prevalent during proliferation, is replaced by type I collagen.[17] Originally disorganized collagen fibers are rearranged, cross-linked, and aligned along tension lines.[32] The onset of the maturation phase may vary extensively, depending on the size of the wound and whether it was initially closed or left open,[28] ranging from approximately 3 days[42] to 3 weeks.[58] The maturation phase can last for a year or longer, similarly depending on wound type.[28]