who has struck out the most in major league history
List of Major League Baseball career strikeouts by batters leaders Reggie Jackson holds the record for the most career strikeouts by a batter with 2,597. Jim Thome (2,548), Adam Dunn (2,379), Sammy Sosa (2,306), Alex Rodriguez (2,287) and Andres Galarraga (2,003) are the only other hitters to strikeout over 2,000 times.