what stage of the cell cycle does p53 work
p53 Activated p53 binds DNA and activates expression of several genes including microRNA miR-34a,[33] WAF1/CIP1 encoding for p21 and hundreds of other down-stream genes. p21 (WAF1) binds to the G1-S/CDK (CDK4/CDK6, CDK2, and CDK1) complexes (molecules important for the G1/S transition in the cell cycle) inhibiting their activity.