when one of a kitten's eyes was sewn shut the main changes in the visual system affected the
Monocular deprivation David Hubel and Torsten Wiesel (who won the Nobel prize in Physiology for their elucidation of receptive field properties of cells in primary visual cortex) first performed the technique in felines.[1] Cats (or kittens), although less-closely related evolutionarily to humans even than rodents, have a remarkably similar visual system to humans. They found that ocular dominance columns (the orderly clustering of V1 neurons representing visual input from one or both eyes) were dramatically disrupted when one eye was sewn shut for 2 months. In the normal feline, about 85% of cells are responsive to input to both eyes; in the monocularly-deprived animals, no cells receive input from both eyes.[2]