where does red blood cell production occur in adults
Red blood cell In humans, mature red blood cells are flexible and oval biconcave disks. They lack a cell nucleus and most organelles, in order to accommodate maximum space for hemoglobin; they can be viewed as sacks of hemoglobin, with a plasma membrane as the sack. Approximately 2.4 million new erythrocytes are produced per second in human adults.[2] The cells develop in the bone marrow and circulate for about 100â€“120 days in the body before their components are recycled by macrophages. Each circulation takes about 60 seconds (one minute).[3] Approximately a quarter of the cells in the human body are red blood cells.[4][5] Nearly half of the blood's volume (40% to 45%) is red blood cells.