repetitive dna at the end of a eukaryotic chromosome
Telomere Telomeres are repetitive nucleotide sequences located at the termini of linear chromosomes of most eukaryotic organisms. For vertebrates, the sequence of nucleotides in telomeres is TTAGGG.[19] Most prokaryotes, having circular chromosomes rather than linear, do not have telomeres.[20] Telomeres compensate for incomplete semi-conservative DNA replication at chromosomal ends.[21] A protein complex known as shelterin serves to protect the ends of telomeres from being recognised as double-strand breaks by inhibiting homologous recombination (HR) and non-homologous end joining (NHEJ).[22][23]