when the herpesvirus is latent it resides in which area
Virus latency One example is herpes virus family, Herpesviridae, all of which establish latent infection. Herpes virus include chicken-pox virus and herpes simplex viruses (HSV-1, HSV-2), all of which establish episomal latency in neurons and leave linear genetic material floating in the cytoplasm.[3] The Gammaherpesvirinae subfamily is associated with episomal latency established in cells of the immune system, such as B-cells in the case of Epstein-Barr virus.[3][4] Epstein-Barr virus lytic reactivation (which can be due to chemotherapy or radiation) can result in genome instability and cancer.[5] In the case of herpes simplex (HSV), the virus has been shown to fuse with DNA in neurons, such as nerve ganglia[6] or brain cells[citation needed], and HSV reactivates upon even minor chromatin loosening with stress,[7] although the chromatin compacts (becomes latent) upon oxygen and nutrient deprivation.[8]