There will be less of them. Or it will be hooked up in such a way... that it is desensitized or downregulated. So the same amount of drug or internal juice... will elicit a much smaller response.
SieIsreceptors d'unadrogaod'unasecreció recenuncomcardeig durantmoItdetemps, s'encongeixen, se'nredueix eInomcre oesconnecten demaneraques'insensiciIitzen.