He has stated in interviews that he suffered from severe depression in the late 1980s and early 1990s, to the point of contemplating suicide, for reasons having to do with his troubled first marriage, his perceived failure as a husband and a father, his father Harold's death, and Freddie Mercury's illness and death.
Brian on intervjuudes öelnud, et võitles 1980ndate lõpus sügava depressiooniga ning kaalus isegi enesetappu, pidades põhjusteks abielu purunemist ja enda halva isana tundmist, oma isa Haroldi surma ja Freddie Mercury haigust.