Like the other very large viruses Mimivirus and Megavirus, Pandoravirus infects amoebas, but its genome, containing 1.9 to 2.5 megabases of DNA, is twice as large as that of Megavirus, and it differs greatly from the other large viruses in appearance and in genome structure.
Nagu ka teised väga suured viirused Mimivirus ja Megavirus, nakatab pandooraviirus amööbe, kuid selle genoom, mis sisaldab 1,9-2,5 miljonit DNA aluspaari, on ligikaudu kaks korda suurem kui Megavirus, samuti erineb pandooraviirus neist nii välimuse kui ka genoomi struktuuri poolest.