This may apply to individuals (e.g., the dose makes the poison: a small amount has no significant effect, a large amount is fatal), or to populations (e.g.: how many people or organisms are affected at different levels of exposure).
Ovaj parameter se može odnositi na pojedinca (e.g.: mala količina nema znatnog uticaja, velika količina je fatalna), ili na populacije (e.g.: na koliko ljudi ili organizama deluju različiti nivoi izlaganja).