A cleavage by thrombin between residue Arg37 and Gly38 on the N-terminus of the A subunit, leads to the release of the activation peptide (MW 4000 da).
Presecanje trombinom između ostataka Arg37 i Gly38 na N-terminusu A podjedinice dovodi do oslobađanja aktivacionog peptida (MW 4000 Da).