In many species, including amphibians, reptiles, rodents and birds, corticosterone is a main glucocorticoid, involved in regulation of energy, immune reactions, and stress responses.
Kod mnogih vrsta, kao što su vodozemci, reptili, glodari i ptice, kortikosteron je glavni glukokortikoid, koji učestvuje u regulaciji energije, imunskim reakcijama, i responsu na stres.