The indole 2-methyl derivative has the ratio of affinities reversed however, with a Ki of 8 nM at CB1 and 29 nM at CB2, which contrasts with the usual trend of 2-methyl derivatives having increased selectivity for CB2 (cf. JWH-018 vs JWH-007, JWH-081 vs JWH-098).
Indol 2-metilni derivat ima suprotni odnos afiniteta, Ki od 8 nM za CB1 i 29 nM za CB2, što je u kontrastu sa neobičnim trendom da 2-metil derivat ima povećanu selektivnost za CB2 (cf. JWH-018 vs JWH-007, JWH-081 vs JWH-098).