Many members of this family also include two histidines in a sequence motif: R+HHC+XCG, where + represents a charged residue and X any residue The FYVE finger is structurally similar to the RING domain and the PHD finger.
Mnogi članovi ove familije takođe sadrže dva histidina u motivu: R+HHC+XCG, gde + označava naelektrisane ostatke, a X bilo koji ostatak FYVE prst je strukturno sličan sa RING domenom i PHD prstom.