Both Gα-GTP and Gβγ can then activate different signaling cascades (or second messenger pathways) and effector proteins, while the receptor is able to activate the next G protein.
Gα-GTP i Gβγ mogu da aktiviraju različite signalne kaskade (ili puteve sekundarnih glasnika) i efektorskih proteina, dok je receptor spreman da aktivira sledeći G protein.