Disruption of the HMG CoA-reductase pathway at the level of FPPS prevents the formation of two metabolites (farnesol and geranylgeraniol) that are essential for connecting some small proteins to the cell membrane.
Poremećaj u putu HMG CoA-reduktaze na FPP nivou sprečava formiranje dva metabolita (farnesol i geranilgeraniol) koji su neophodni za vezivanje grupe malih proteina за ćelijsku membranu.