In a hypothetical example, the factors A and B might regulate a distinct set of genes from the combination of factors A and C. This combinatorial nature extends to complexes of far more than two proteins, and allows a very small subset (less than 10%) of the genome to control the transcriptional program of the entire cell.
U hipotetičkom primeru, faktori A i B mogu regulisati poseban skup gena iz kombinacije faktora A i C. Ova kombinatorna priroda proširuje se na komplekse daleko više od dva proteina i omogućava vrlo malo podskup (manje od 10% ) genoma za kontrolu transkripcionog programa celokupne ćelije.