Inverse agonists inhibit the constitutive activity of the receptor, producing functional effects opposite to those of agonists (at the 5-HT7 receptor: ↓cAMP).
Inverzni agonisti inhibiraju konstitutivnu aktivnost receptora, čime proizvode funkcionalne efekte suprotne agonistima (kod 5-HT7 receptora: ↓cAMP).