Since many isoforms of PKC are also activated by increases in intracellular Ca2+, both these pathways can also converge on each other to signal through the same secondary effector.
Pošto su mnoge PKC izoforme takođe aktivirane povišenim nivoima intracelularnog Ca2+, ova dva puta mogu međusobno da konvergiraju i prenesu signal istim sekundarnim efektorom.