This means that herkinorin may not produce tolerance and dependence in the same way as other opioids, although some development of tolerance through other mechanisms has been observed, and some other analogues related to herkinorin can recruit β-arrestins.
To znači da herkinorin možda ne proizvodi toleranciju i zavisnost za razliku od drugih opioida, mada je razvoj tolerancije putem drugih mehanizama bio zapažen, i neki drugi analozi srodni herkinorinu mogu da regrutuju β-arestine.