It is generally assumed that ATP hydrolysis provides the principal energy input or "power stroke" for transport and that the NBDs operate alternately and are possibly involved in different steps in the transport cycle.
Generalno se podrazumeva da ATP hidroliza pruža glavni energetski input ili podsticaj za transport i da NBD domeni deluju naizmenično, kao i da je moguće da učestvuju u različim koracima transpornog ciklusa.