The general mechanism for the transport cycle of ABC transporters has not been fully elucidated, but substantial structural and biochemical data has accumulated to support a model in which ATP binding and hydrolysis is coupled to conformational changes in the transporter.
Opšti mehanizam transportnog ciklusa ABC transportera nije u potpunosti razjašnjen mada postoji znatna količina strukturnih i biohemijskih podata koji podržavaju model u kome su ATP vezivanje i hidroliza spregnuti sa konformacionim promenama transportera.