Loss of the 29 copies of SNORD116 (HBII-85) from this region has been identified as a cause of Prader-Willi syndrome whereas gain of additional copies of SNORD115 has been linked to autism.
A perda das 29 copias de SNORD116 desta rexión é a causa da síndrome de Prader-Willi e a ganancia de copias adicionais de SNORD115 foi asociada co autismo.