Hexokinase I/A is found in all mammalian tissues, and is considered a "housekeeping enzyme," unaffected by most physiological, hormonal, and metabolic changes.
A hexoquinase I/A encóntrase en todos os tecidos de mamífero, e considérase un "encima de mantemento" (housekeeping enzyme) que non se ve afectado pola maioría dos cambios metabólicos, hormonais e fisiolóxicos.