In 1964, Bergström and Samuelsson linked these observations when they showed that the "classical" eicosanoids were derived from arachidonic acid, which had earlier been considered to be one of the essential fatty acids.
En 1964, Bergström e Samuelsson asociaron estas observacións coa síntese dos eicosanoides "clásicos", que afirmaron que derivaban do ácido araquidónico, que fora antes considerado un ácido graxo esencial.