In addition to undergoing the reactions characteristic of internal alkynes, terminal alkynes are reactive as weak acids, with pKa values (25) between that of ammonia (35) and ethanol (16).
Ademais de sufriren as reaccións características dos alquinos internos, os alquinos terminais son reactivos como ácidos febles, con valores de pKa de 25 entre os do amoníaco (35) e o etanol (16).