FANCF stabilizes the interaction between the FANCC/FANCE subcomplex and the FANCA/FANCG subcomplex and locks the whole FA core complex in a conformation that is essential to perform its function in DNA repair.
FANCF estabiliza a interacción entre os subcomplexos FANCC/FANCE e FANCA/FANCG e pecha o núcleo do compleco FA nunha conformación que é esencial para realizar a súa función na reparación do ADN.