Generally, the 155 aa/18 kDa low molecular weight (LMW) form is considered cytoplasmic and can be secreted from the cell, whereas the high molecular weight (HMW) forms are directed to the cell's nucleus.
Xeralmente, a forma de 155 aminoácidos/18 kDa de baixo peso molecular (LMW) considérase citoplásmica e pode ser segregada da célula, mentres que as formas de alto peso molecular (HMW) son dirixidas ao núcleo celular.