Auxotrophic selection markers that allow an auxotrophic organism to grow in minimal growth medium may also be used; examples of these are LEU2 and URA3 which are used with their corresponding auxotrophic strains of yeast.
Poden usarse tamén marcadores de selección auxotróficos que permiten que un organismo auxotrófico creza nun medio de crecemento mínimo; exemplos deles son LEU2 e URA3, que se utilizan coas correspondentes cepas auxotróficas de lévedos.