However, it has been shown that there is significant neuron loss before the formation of neurofibrillary tangles, and that NFTs account for only a small proportion (around 8.1%) of this neuron loss.
Porén, demostrouse que hai unha perda significativa de neuronas antes da formación de nobelos neurofibrilares, e que os nobelos neurofibrilares explican só unha pequena proporción (arredor do 8,1%) desta perda neuronal.