The Polony sequencing method, developed in the laboratory of George M. Church at Harvard, was among the first high-throughput sequencing systems and was used to sequence a full E. coli genome in 2005.
O método de secuenciación Polony (contracción de polymerase colony) desenvolvido no laboratorio de George M. Church en Harvard, foi un dos primeiros sistemas de secuenciación de seguinte xeración e foi usado para secuenciar un xenoma completo en 2005.