Initial studies reported that the sorting of isoforms changed through development, where Tropomyosin 4 was initially localized to the growth cone of growing neurons, but in mature neurons it was relocated to the somatodendritic compartment.
Os estudos iniciais informaron que a distribución das isoformas cambiaba durante o desenvolvemento, e que a tropomiosina 4 estaba localizada inicialmente no cono de crecemento das neuronas en crecemento, pero que nas neuronas maduras estaba situado no compartimento somatodendrítico.