Mice born without the ability to make BDNF suffer developmental defects in the brain and sensory nervous system, and usually die soon after birth, suggesting that BDNF plays an important role in normal neural development.
Os ratos nacidos sen a capacidade de producir o BDNF sofren defectos de desenvolvemento no cerebro e sistema nervioso sensorial, e adoitan morrer pouco despois do nacemento, o que indica que o BDNF desempeña un importante papel no desenvolvemento neural normal.