However, oxygenation of 10,10-difluoroarachidonic acid to 11-(S )-hydroxyeicosa-5,8,12,14-tetraenoic acid is not consistent with the generation of a carbanion intermediate because it would eliminate fluoride to form a conjugated diene.
Porén, a oxixenación do ácido 10,10-difluoroaraquidónico a ácido 11-(S )-hidroxieicosa-5,8,12,14-tetraenoico non é consistente coa xeración dun intermediario carbanión porque eliminaría fluoruro para formar un dieno conxugado.