The formal study of systems biology, as a distinct discipline, was launched by systems theorist Mihajlo Mesarovic in 1966 with an international symposium at the Case Institute of Technology in Cleveland, Ohio, titled "Systems Theory and Biology".
O estudo formal da bioloxía dos sistemas como disciplina distinta foi lanzado polo teórico de sistemas Mihajlo Mesarovic en 1966 durante un simposio internacional no Case Institute of Technology en Cleveland, Ohio intitulado "Systems Theory and Biology."