All five members discovered so far directly activate Cdk1 and Cdk2, but the RINGO/Speedy-CDK2 complex recognizes different substrates than cyclin A-CDK2 complex.
Os cinco membros descubertos ata agora activan todos directamente a Cdk1 e Cdk2, pero o complexo RINGO/Speedy-CDK2 recoñece diferentes substratos que o complexo ciclina A-CDK2.