With the exception of Entamoeba gingivalis, which lives in the mouth, and E. moshkovskii, which is frequently isolated from river and lake sediments, all Entamoeba species are found in the intestines of the animals they infect.
Coa excepción de Entamoeba gingivalis, que vive na boca, e E. moshkovskii, que se illa con frecuencia en sedimentos de ríos e lagos, todas as especies de Entamoeba se encontran nos intestinos dos animais aos que infectan.