In Europe, British Airways, Iberia, and Icelandair were the 757's largest mainline customers, while other carriers such as Lufthansa rejected the type as too large for their narrow-body aircraft needs.
En Europa, British Airways, Iberia, e Icelandair foron os principais clientes do 757, pentres que outras aeroliñas como Lufthansa rexeitaron o modelo por ser demasiado grande para as súas necesidades dun avión de fuselaxe estreita.