In regard to the potential benefit that drug-resistant cells can be recruited for effective therapy by combining chemotherapy with hyperthermia, it was important to show that chemoresistance against several anticancer drugs (e.g. mitomycin C, anthracyclines, BCNU, melphalan) including CDDP could be reversed at least partially by the addition of heat.
En canto ao beneficio potencial de que as células resistentes ao fármaco poidan ser recrutadas para unha terapia efectiva combinando a quimioterapia con hipertermia, é importante mostrar que a quimiorresistencia contra varios fármacos aniticancro (por exemplo, a mitomicina C, antraciclinas, BCNU, melfalán) incluíndo a CDDP podería ser revertida polo menos parcialmente pola adición de calor.