In 1464, during the First Ottoman–Venetian War, Lemnos and other former Gattilusi possessions were seized by the Venetians, but were returned to the Ottomans by the 1479 Treaty of Constantinople.
En 1467, durante a Primeira Guerra otomá-veneciana, Lemnos e outras antigas posesións dos Gattilusi foron capturados polos venecianos, pero foron devoltos aos otománs en 1479 polo Tratado de Constantinopla.