Adaptins are distantly related to the other main type of vesicular transport proteins, the coatomer subunits, sharing between 16% and 26% of their amino acid sequence.
As adaptinas están distantemente relacionadas con outros tipos importantes de proteínas de transporte vesicular, as subunidades coatómeros, que comparten entre o 16% e o 26% da súa secuencia de aminoácidos.