The N172 residue (as part of the YMNM) is important for the binding of Grb2 and Gads and seems to be able to induce IL-2 mRNA stability but not NF-κB translocation.
O residuo N172 (como parte do YMNM) é importante para a unión de Grb2 e Gads e parece poder inducir a estabilidade do ARNm de IL-2, pero non a translocación de NF-κB.