These chronic, age-associated increases in microglial activation and IL-1 expression may contribute to increased risk of Alzheimer's disease with advancing age through favoring neuritic plaque formation in susceptible patients.
Este incremento da activación microglial e da expresión de IL-1 crónico asociado coa idade pode contribuír a aumentar o risco de enfermidade de Alzheimer conforme envellecemos ao favorecer a formación de placas neuríticas en pacientes susceptibles.