Between 1933 and 1936, Connaught Medical Research Laboratories, then a part of the University of Toronto, perfected a technique for producing safe, nontoxic heparin that could be administered to patients, in a saline solution.
Entre 1933 e 1936, os Connaught Medical Research Laboratories, que entón formaban parte da Universidade de Toronto, perfeccionaron unha técnica para producir heparina segura e non tóxica que podía ser administrada aos pacientes en solución salina.