The discovery of the coxsackieviruses stimulated many virologists to use this system, and ultimately resulted in the isolation of a large number of so-called "enteric" viruses from the gastrointestinal tract that were unrelated to poliovirus, and some of which were oncogenic (cancer-causing).
O descubrimento dos coxsackievirus estimulou a moitos virólogos a usar este sistema, e finalmente deu lugar ao illamento dun grande número dos chamados virus "entéricos" a partir do tracto gastrointestinal, que non estaban relacionados co poliovirus, e algúns dos cales eran oncoxénicos (causantes de cancro).