Pagani's car racing exploits resulted in wins at the Pau Grand Prix in 1947 and 1948, before his single Formula One World Championship Grand Prix, on 4 June 1950, in the 1950 Swiss Grand Prix at Bremgarten.
Os mellores resultados nas carreiras de automobilismo de Pagani foron as vitorias no Pau Grand Prix en 1947 e 1948, antes de disputar o seu único GP de Fórmula Un, o 4 de xuño de 1950, no Gran Premio de Suíza de 1950 en Bremgarten.