As with some other coagulation factors, the factor was initially named after these patients, a Mr Rufus Stuart (1921) and a Miss Audrey Prower (1934).
Igual que algúns outros factores de coagulación, o factor foi inicialmente nomeado polo nome dos pacientes nos que se atopou a deficiencia, chamados Rufus Stuart (1921) e Audrey Prower (1934), polo que se denominou factor de Stuart-Prower.