A heated debate arose when Kimura's theory was published, largely revolving around the relative percentages of alleles that are "neutral" versus "non-neutral" in any given genome.
Cando se publicou a teoría de Kimura orixinouse un acalorado debate, que en gran medida xiraba arredor das porcentaxes relativas dos alelos que son "neutros" fronte aos "non neutros" nun xenoma dado.