In 2008 evolutionary biologist Olivia Judson in her article The Monster Is Back, and It’s Hopeful listed some examples which may support the hopeful monster hypothesis and an article published in the journal Nature in 2010 titled Evolution: Revenge of the Hopeful Monster reported that studies in stickleback populations in a British Columbia lake and bacteria populations in a Michigan lab have shown that large individual genetic changes can have vast effects on organisms "without dooming it to the evolutionary rubbish heap".
En 2008 a bióloga evolutiva Olivia Judson no seu artigo The Monster Is Back, and It’s Hopeful fixo unha lista de exemplos que podían apoiar a hipótese do mostro optimista e un artigo publicado na revista Nature en 2010 titulado Evolution: Revenge of the Hopeful Monster informaba que estudos en poboacións do peixe espiñento nun lago de Columbia Británica e as poboacións de bacterias nun laboratorio de Míchigan mostraron que grandes cambios xenéticos individuais poden ten vastos efectos sobre os organismos "sen condenalos ao monte de lixo evolutivo".