However, studies have demonstrated that serine palmitoyltransferase has some activity toward other species of fatty acyl-CoA and alternative amino acids, and the diversity of sphingoid bases has recently been reviewed.
Porén, certos estudos demostraron que a serina palmitoiltransferase ten tamén certa actividade sobre outras especies de acilo graxo-CoA e aminoácidos alternativos á serina, e a diversidade das bases dos esfingolípidos foi recentemente revisada.