While relatively little is known about the role MET plays in cancer when compared to the extensive studies of EMT in tumor metastasis, MET is believed to participate in the establishment and stabilization of distant metastases by allowing cancerous cells to regain epithelial properties and integrate into distant organs.
Aínda que se sabe relativamente pouco do papel que exerce a TME no cancro se a comparamos co amplamente estudado papel da TEM na metástase de tumores, a TME crese que participa no establecemento e estabilización de metástases distantes ao permitir que as células cancerosas recuperen propiedades epiteliais e se integren en órganos afastados do foco canceroso inicial.