Although the RT structures from human, murine and avian retroviruses display different subunits, the relative sizes, orientation and connection of the DNA polymerase and RNase H domains are strikingly similar.
Aínda que as estruturas das RT de retrovirus de humanos, murinos e aves presentan diferentes subunidades, os tamaños relativos, a orientación e conexión dos dominios de RNase H ou ADN polimerase son moi similares.