Plasmodium vivax has become chloroquine and sulfadoxine-pyrimethamine resistant a few decades ago, and as of 2012 artemisinin-resistant Plasmodium falciparum has emerged in western Cambodia and western Thailand.
Plasmodium vivax fíxose resistente á cloroquina e á sulfadoxina-pirimetamina hai unhas décadas, e en 2012 apareceu un Plasmodium falciparum resistente á artemisinina no oeste de Camboxa e oeste de Tailandia.