The prothrombin time was developed by Dr Armand Quick and colleagues in 1935, and a second method was published by Dr Paul Owren, also called the "p and p" or "prothrombin and proconvertin" method.
Protrombinový čas objevil Dr.Armand Quick a kol. v roce 1935 a druhou metodu publikoval Dr Paul Owren (také nazývaná "p a p" nebo metoda stanovení "protrombinu a prokonvertinu").