Direct spin-offs of the first title in the Serious Sam series were created for PlayStation 2, GameCube and Game Boy Advance by Climax Solent and for Palm OS by InterActive Vision.
Přímé spin-off tituly prvních titulů série Serious Sam byly vytvořeny pro PlayStation 2, GameCube a Game Boy Advance společností Climax Solent a pro Palm OS od InterActive Vision.