Following the 2006 elections, Shas were invited to join Ehud Olmert's coalition, and Yishai was made Minister of Industry, Trade, and Labour, as well as being a Deputy Prime Minister.
Po volbách v roce 2006 byla strana Šas přizvána koalice Ehuda Olmerta a Jišaj se stal ministrem průmyslu, obchodu a práce a také vicepremiérem.