25
Below is an instruction that describes a task. Write a response that appropriately completes the request.

### Instruction:
Find the missing number in this sequence: 0, 1, 4, 9, 16, __

### Response:
25
assistant

To find the missing number in the sequence, we need to identify the pattern. The given sequence appears to be a sequence of perfect squares:

0² = 0
1² = 1
4² = 16
9² = 81
16² = 256

The pattern suggests that the missing number in the sequence is 25.

Therefore, the correct sequence is: 0, 1, 4, 9, 16, 25