Treatment failure also leads to longer periods of infectivity, which increases the numbers of infected people and thus expose the general population to the risk of contracting a resistant strain of infection.
Ebaõnnestunud raviga kaasnevad ka pikemad nakkusperioodid, mille tulemusena suureneb nakatunud inimeste arv ning tekib kogu elanikkonna jaoks resistentsesse nakkusesse nakatumise oht.