This genetic mutation appears in many ethnic groups, but it is especially frequent in a large population of Hispanic Americans living in the Southwest; these individuals share a common ancestor in whom the genetic change occurred.
See geneetiline mutatsioon näib paljude etniliste rühmade, kuid see on eriti sagedased suurele hulgale Hispanic ameeriklased elavad Puhub; neid inimesi on ühine esivanem, kelle geneetiline muutus toimus.