Even in patients who have the genetic background that predisposes them to developing reactive arthritis, however, exposure to certain infections seem to be required to trigger the onset of the disease.
Isegi patsientidel, kellel on geneetiline taust, eelduseks, neid arendada reaktiivne artriit, siiski, kokkupuude teatavate infektsioonide näivad olevat vajalik, et käivitada haiguspuhangut.