Studies have shown that individuals who are prone to migraines can have their headaches brought on by histamine, which is one of the compounds that mast cells produce in an allergic reaction.
Uuringud on näidanud, et isikud, kes on altid migreen võib olla nende peavalu toonud poolt histamiini, mis on üks ühendeid, mis nuumrakkudest toota allergiline reaktsioon.