The CoR has been involved in the development of territorial cooperation in the framework of the Eastern Partnership since it was launched by the Czech presidency of the EU in May 2009.
Regioonide Komitee on kaasatud territoriaalse koostöö edendamisse idapartnerluse raames alates ajast, mil ELi eesistujariik Tšehhi Vabariik käivitas selle 2009. aasta mais.