A 50 year old man presented with mild abdominal pain with mildly raised ALT and AST. Fatty liver was suspected, which of the following changes is not seen ultrastructurally in this condition?
A. Generalized swelling of cell and plasma membrane.
B. Nuclear changes such as pyknosis, karyorrhexis and karyolysis are seen.
C. Accumulation of “myelin figures” in the cytosol composed of phospholipids derived from damaged cellular membranes.
D. Dilation of the ER, with detachment of polysomes.
Answer:B
A 50 year old man presented with mild abdominal pain with mildly raised ALT and AST. Fatty liver was suspected, which of the following changes is not seen ultrastructurally in this condition?
A. Generalized swelling of cell and plasma membrane. B. Nuclear changes such as pyknosis, karyorrhexis and karyolysis are seen. C. Accumulation of “myelin figures” in the cytosol composed of phospholipids derived from damaged cellular membranes. D. Dilation of the ER, with detachment of polysomes.