The rapid appearance of HIV-1 strains that are resistant to AIDS drugs is due in part to which of the following property of its reverse transcriptase?
A. AZT (zidovudine) is too expensive to be taken in effective doses
B. The RNase H domain of p66 causes error prone synthesis
C. It lacks a proofreading exonuclease
D. It has low affinity for the correct dNTP’s
Answer:C
The rapid appearance of HIV-1 strains that are resistant to AIDS drugs is due in part to which of the following property of its reverse transcriptase?
A. AZT (zidovudine) is too expensive to be taken in effective doses B. The RNase H domain of p66 causes error prone synthesis C. It lacks a proofreading exonuclease D. It has low affinity for the correct dNTP’s