The treatment for malignant lymph node disease is based upon a number of factors, including the site of the primary tumor (e.g., bowel) and its histological cell type. Normally, the primary tumor is surgically removed and the lymph node spread and metastatic organ spread (e.g., to the liver and the lungs) are often treated with chemotherapy and radiotherapy.
In certain instances it may be considered appropriate to resect the lymph nodes in the retroperitoneum (e.g., for testicular cancer).