The recurrent branch of the median nerve innervates the three thenar muscles. Originating from the lateral side of the median nerve near the distal margin of the flexor retinaculum, it curves around the margin of the retinaculum and passes proximally over the flexor pollicis brevis muscle. The recurrent branch then passes between the flexor pollicis brevis and abductor pollicis brevis to end in the opponens pollicis.