The muscle in the intermediate layer of the anterior compartment of the forearm is the flexor digitorum superficialis muscle (Fig. 7.86). This large muscle has two heads: the humero-ulnar head, which originates mainly from the medial epicondyle of the humerus and from the adjacent medial edge of the coronoid process of the ulna; and the radial head, which originates from the anterior oblique line of the radius.