The enteric nervous system consists of motor and sensory neurons and their support cells, which form two interconnected plexuses, the myenteric and submucous nerve plexuses, within the walls of the gastrointestinal tract (Fig. 1.48). Each of these plexuses is formed by: ganglia, which house the nerve cell bodies and associated cells, and bundles of nerve fibers, which pass between ganglia and from the ganglia into surrounding tissues.