The tuberal region in the medial zone contains three nuclei: ventromedial, dorsomedial, and arcuate. The largest and best defined is the ventromedial nucleus, which functions as a satiety center to decrease feeding behavior. Posterior to the ventromedial nucleus is the dorsomedial nucleus, which functions in the behavioral expression of rage or aggressive behavior. Finally, the arcuate nucleus serves as a center for releasing hormones, which are transmitted by the tuberoinfundibular tract and hypophysial portal system to the anterior pituitary (eFig. 9.89).