The second palmar interosseous muscle originates from the medial surface of metacarpal II and inserts into the medial side of the extensor hood of the index finger.
The third and fourth palmar interossei originate from the lateral surfaces of metacarpals IV and V and insert into the lateral sides of the respective extensor hoods.
Like the tendons of the dorsal interossei, the tendons of the palmar interossei pass dorsal to the deep transverse metacarpal ligaments.