The orifices of the urethra and the vagina are associated with the openings of glands. The ducts of the para-urethral glands (Skene’s glands) open into the vestibule, one on each side of the lateral margin of the urethra. The ducts of the greater vestibular glands (Bartholin’s glands) open adjacent to the posterolateral margin of the vaginal opening in the crease between the vaginal orifice and remnants of the hymen.