---
language: en
tags:
  - diffusion-models
  - medical-imaging
  - glioma
  - synthetic-data
  - MRI
license: mit
datasets:
  - BraTS2024
model-index:
  - name: GliomaGen
    results:
      - task:
          type: image-generation
        dataset:
          name: BraTS2024 Adult Post-Treatment Glioma
          type: medical-imaging
        metrics:
          - name: FID (t1c)
            type: frechet-inception-distance
            value: 55.2028 ± 3.7446
          - name: FID (t2w)
            type: frechet-inception-distance
            value: 54.9974 ± 3.2271
          - name: KID (t1c)
            type: kernel-inception-distance
            value: 0.0293 ± 0.0019
          - name: MS-SSIM (t1c)
            type: multi-scale-structural-similarity
            value: 0.7647 ± 0.2106
---

# GliomaGen: Conditional Diffusion for Post-Treatment Glioma MRI Generation
GliomaGen is a generative diffusion model tailored for synthesizing post-treatment glioma MRI images based on anatomical masks. It leverages a modified **Med-DDPM** architecture to create high-fidelity MRI images conditioned on segmented anatomical features.

## Model Overview
GliomaGen aims to address data scarcity in post-treatment glioma segmentation tasks by expanding existing datasets with synthetic, high-quality MRI volumes. The model takes anatomical masks as input and generates multi-modal MRI scans conditioned on segmentation labels.

## Model Performance
### **Quantitative Metrics**
| Modality | FID (↓) | KID (↓) | MS-SSIM (↑) |
|----------|--------|--------|-------------|
| t1c      | 55.20 ± 3.74 | 0.0293 ± 0.0019 | 0.7647 ± 0.2106 |
| t2w      | 54.99 ± 3.23 | 0.0291 ± 0.0010 | 0.6513 ± 0.2881 |
| t1n      | 58.46 ± 3.86 | 0.0305 ± 0.0011 | 0.7005 ± 0.2585 |
| t2f      | 70.42 ± 4.17 | 0.0370 ± 0.0018 | 0.7842 ± 0.1551 |


## Usage
To use GliomaGen for MRI generation, see the [GitHub repository](https://github.com/elijahrenner/gliomagen). 

## BraTS 2024 Adult Post-Treatment Glioma-Synthetic
Alongisde GliomaGen, a synthetic dataset of $N=2124$ MR images is released on HuggingFace.