If Zyrtec and Flonase aren't working for severe allergic rhinitis, what should I try?

  • Q: I have severe allergic rhinitis. Zyrtec and Flonase aren't working. What should I try?
  • A: Allergic rhinitis is the result of exposure to allergens in the environment. The exposure causes a response from the immune system releasing chemicals like histamine. This release can lead to the itching, watery eyes, and running nose typically associated with allergic rhinitis. Alternative antihistamines, such as Allegra (fexofenadine) or Claritin (loratadine), make work better for some patients than Zyrtec. Likewise, besides Flonase, other nasal cortisteroids like Rhinocort (budesonide) or Nasonex (mometasone) are available to blunt the immune system response. It is important to remember that, while these medications are similar, some patients have more success with some drugs over other ones. When recommended treatments fail to relieve the symptoms, the best option to consult a physician. Allergen testing is possible to find the exact cause of rhinitis. Other prescription remedies could be an option as well. Singular (montelukast) is possible addition to your therapy. Also, any alternatives to your Flonase would have to be prescribed. Ultimately, your doctor will be able further evaluate your condition to determine the best next step. Jeff O'Connell, PharmD, RPh
This question was answered on October 08, 2010.


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