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In 2004, Oprah interviewed Barbara for O, The Oprah Magazine. At that time, she shared her regrets, passions and what she knew for sure. Four years later, she's changing her answer.

"What do you now know for sure?" Oprah asks.

"You must have someone or something to love, even if it's a dog or a cat," she says. "You must have a reason to get up in the morning, and it doesn't have to be a career. You must have something beyond yourself—spirituality, religion, I don't care what you call it—something that makes you know that there's something out there beyond you."

As she gets older, Barbara says she knows more about how to treat others. "You must be kind, which is why I'm not going to be a very good interviewer anymore," she says. "I'm getting too soft."

After almost 80 years, Barbara has come to one final conclusion: "I've stopped auditioning."