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...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.

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Class 422/70 - Liquid chromatography

Subclass of Class 422 - Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
Definition: Apparatus specifically designed or adapted for liquid chromas:graphic
No. of patents: 793
Last issue date: 02/18/2014

NumberTitleIssue Date
8652420Device for the distribution of sample and carrier liquid across a micro-fabricated separation channel
The present invention relates to a chromatographic separation device comprising a first substrate body carrying a micro-fabricated separation channel recessed on one of its surfaces and covered by a second substrate body, both perforated with connection-holes for th...
8647576Electrolytic eluent generator and method of use
An acid or base is generated in an aqueous solution by the steps of: (a) providing a source of first ions adjacent an aqueous liquid in a first acid or base generation zone, separated by a first barrier (e.g., anion exchange membra...
8636963Chemical suppressors and method of use
A non-electrolytic method and apparatus for treating an aqueous sample stream including analyte ions and matrix ions of opposite charge, for pretreatment or suppression. The apparatus includes an ion exchange membrane capable of passing only ions of opposite charge ...
8623279Ionic liquid mediated sol-gel sorbents
Ionic liquid (IL)-mediated sol-gel hybrid organic-inorganic materials present enormous potential for effective use in analytical microextraction. One obstacle to materializing this prospect arises from high viscosity of ILs significantly slowing down sol-gel reactio...
8597571Electrolytic eluent recycle device, apparatus and method of use
Electrolytic eluent recycle systems for ion chromatography using a multi-channel electrolytic ion exchange device which integrates suppression, eluent generation, and eluent recycle. The systems recycle the eluent into the analytical system without passing the eluen...
8562910Method and apparatus for analysis of poly (biphenyl chloride) in electrical insulating oil
An object of the present invention is to provide a method and an apparatus by which PCBs in insulating oil can be analyzed with high accuracy in a convenient, inexpensive, and rapid manner. The method for analyzing polychlorobiphenyls by measuring the concentration ...
8425842Suppressor and ion chromatograph employing the same
A suppressor which comprises: an ion-exchange membrane; an eluate channel which is in contact with one side of the ion-exchange membrane, serves as a channel through which an eluate discharged from a separation column flows, and has inside no obstacle to the flow; a...
8361390Liquid chromatograph
The present invention relates to a liquid chromatography apparatus X, which is provided with a deaerator 4. The liquid chromatography apparatus X is further provided with a dissolved oxygen density adjusting means for maintaining a density of dissolved oxygen...
8323569Apparatus for method for polymer characterization
Apparatus for GPC/TREF and TREF/GPC characterization of a polymer sample. The apparatus provides for the automated and integrated use of multiple TREF columns and a GPC system employing a multiple flow through detectors. In addition, a method for TREF/GPC characteri...
8216515Capillary ion chromatography
An apparatus for capillary ion chromatography having a suppressor having flow-through ion exchange packing in a housing and capillary tubing formed of a permselective ion exchange membrane, and at least partially disposed in said ion exchange packing. Also, a recycl...
8187539Device and method for determining material properties by means of HPLC
An assembly for determining material properties and/or material concentrations of components of a sample, containing: a chromatographic separating column with a liquid mobile solvent; means for controlling the temperature inside the separating column between room te...
8173070Sample injector system for liquid chromatography
An injection device (10) includes a carrier inlet (40), a sample inlet (46), waste outlet (44) and a chamber outlet (64) attached to separation column (66). Valves (52, 54, 56) are used to control flow such that sampl...
8007742IRIS digester-evaporator interface
A digester-evaporator for partially digesting a sample and for evaporating the solvent after partial digestion. The digester includes at least one reaction coil; a heating element arranged along a portion of the reaction coil; at least a portion of the reaction coil...
7976779Integrated LC-ESI on a chip
A microfluidic system with on-chip pumping which can be used for liquid chromatography and also electrospray ionization mass spectrometry and which provides improved efficiency, better integration with sensors, improved portability, reduced power consumption, and re...
7901628Method for fractionating various components contained in a sample solution by liquid chromatograph mass spectrometer
A method for fractionating a sample solution includes the steps of setting a first mass spectrometry condition and mass range information; setting a second mass spectrometry condition and mass range information; executing a mass scan by the mass spectrum acquisition...
7524457Displacement chemical regeneration method and apparatus
Apparatus for chromatographically separating ionic species in an aqueous electrolyte-containing eluent to form an effluent, suppressing the effluent, detecting the suppressed effluent and passing the detected effluent to a regenerant reservoir, thereby displacing th...
7442556Microfluidic-based electrospray source for analytical devices with a rotary fluid flow channel for sample preparation
This invention provides microfluidic devices and methods for using the same. Microfluidic devices of the present invention comprises a first elastic layer, a fluid flow channel within the elastic layer; and a means for providing a fluid sample from the fluid flow ch...
7425251System and method
A system and method of characterizing, in particular sequencing, polymeric samples, the system comprising: a space-time map generator for generating a space-time map of points representative of the signal peaks of signals detected at a plurality of spaced positions ...
7425252System and method
An analysis system for and method of enabling determination of the velocities of migrating objects, the system comprising an equiphase space-time map generator for generating an equiphase space-time map of equiphase points from each of a plurality of data sets repre...
7416698Molecular topological fractionation of macromolecules
A process for characterizing a sample comprising a population of linear macromolecules of interest (104) and a population of long chain branched macromolecules of interest (103), the process including four steps. The first step is to provide a flow thr...
7405083Method and apparatus for purifying and desalting biological samples
The subject invention provides a sample processing technique for purifying a biological or chemical sample. The invention is particularly well-suited to prepare a sample for mass spectrometry. The process is to be performed in an article having at least one well, in...
7402283Electrolytic eluent generator and method of use
7393691SERS method and apparatus for rapid extraction and analysis of drugs in saliva
The method and apparatus rapidly separate drugs and their metabolites from saliva and, in a continuous sequence of steps, rapidly detect, identify and quantify them through surface-enhanced Raman spectroscopy. ...
7393692SERS method for rapid pharmacokinetic analysis of drugs in saliva
7364701Liquid homogenizing unit and high speed liquid chromatograph equipped with the same
A liquid homogenizing unit comprising a feed flow channel (56), a discharge flow channel (57), a first intermediate flow channel (58) communicating with the feed flow channel (56), and a second intermediate flow channel (55) commun...
7361269Fraction collector with adjustable tray
A fraction collector comprising a movable tray is provided. The movable tray may be attached to the fraction collector support system in a variety of ways and adjusted without adjusting the parts of the fraction collector support system. The moveable tray may be sta...
7361278Process for producing mass transfer device and apparatus for production thereof
A process for producing a mass transfer device is provided which enables packing of a packing material uniformly in a flow channel, and transfers a specified substance by flowing a fluid containing the specified substance through a flow channel on a substrate. A mas...
7357852Bubble-free and pressure-generating electrodes for electrophoretic and electroosmotic devices
Bubble-free electrodes, electrochemical cells including bubble-free electrodes, analytical devices, and methods for preparing and using them are provided. The analytical devices each include at least one bubble-free electrode. Analytical devices that include an elec...
7357864Microfluidic device
The object of the present invention is to provide a production process of a microfluidic device in which a porous resin layer, which is capable of optimally fixing a large amount of enzyme, antigen or other protein or catalyst on the inner surface of a minute channe...
7351245Apparatus and method for dislodging object from throat
An apparatus for sucking out an object stuck in a person's throat, comprising hollow first and second bellows elements each having an orifice with a one-way valve and an exit valve, a tube structure comprising first and second legs having free distal ends outside th...
7347936Liquid chromatograph
A liquid chromatograph has switching valves as a flow passage switching mechanism and an automatic sampler as an injection section. The liquid chromatograph can switch, by switching the switching valves between a concentration flow passage for concentrating the samp...
7341652Stationary capillary electrophoresis system
A system and method for capillary electrophoresis are provided for analyzing a macromolecule prepared from a complex liquid mixture. In particular applications, methods and apparatus are provided for separating and analyzing a solution containing a denatured macromo...
7332347Apparatus and method for concentrating and collecting analytes from a flowing liquid stream
An apparatus for concentrating and collecting one or more analytes in a flowing liquid stream of a carrier solvent composed of one or more solvent components is provided, which includes a transfer tube which forms a bore having an inlet and an outlet, the inlet bein...
7332087Flow sensing apparatus used to monitor/provide feedback to a split flow pumping system
A method and apparatus for monitoring and controlling the nano-scale flow rate of fluid in the operating flow path of a HPLC system without relying on a nano-scale sensor in the operating flow path. A main flow sensor is disposed in the main flow path between the pu...
7329353LC/MS method of analyzing high molecular weight proteins
The present invention is directed to a novel method of analysis of high molecular weight proteins. More specifically, it is directed to a novel reversed-phase LC/MS method of analysis of high molecular weight proteins including antibodies. ...
7329386Column packing material and method for producing the same
The first subject of this invention is a column packing material comprising: a silica gel having a silanol group; a first chemical modification group which is bound to said silanol group; a silicon...
7329346Ion chromatography system using catalytic gas elimination
A liquid chromatographic system is provided including catalytically combining hydrogen and oxygen gases in the chromatography eluent stream in a catalytic gas elimination chamber, to form water and thereby reduce the gas content in the eluent stream. Also, a liquid ...
7323342Method for improving oil desalting by forming unstable water-in-oil emulsions
A method for determination for a given oil the relative stability of a water-in-oil emulsion that will be formed by that oil with water comprises measuring for the given oil the weight fraction of the oil that is most strongly adsorbed on a silica gel column success...
7318900Chromatography system and method
A chromatography system and method for analyzing a sample of interest. The chromatography system can include a housing, a cartridge holder coupled to the housing and formed to hold a chromatography cartridge containing a stationary phase, a collection vessel stand h...
7316769Length-dependent recoil separation of long molecules
Separation of long molecules by length is obtained by forcing such molecules to traverse a boundary between a low free-energy region and a high free-energy region. In one embodiment, the high free-energy region is a dense pillar region or other structure formed on a...
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