Transforming radiotherapy

Our small-molecule dismutase mimetics are designed to utilize the potential of increasing dismutase activity, which may be key to reducing treatment-related side effects and helping treat cancer.

Dismutase mimetics convert superoxide to hydrogen peroxide and molecular oxygen. The metabolic processing of superoxide is a critical cellular function and part of the broader oxygen metabolic pathways that keep cells functioning. While oxygen metabolic pathways are involved in a host of diseases, Galera is initially focused on changing how radiotherapy is used in cancer patients to both reduce the side effects of radiation therapy and enhance the therapeutic effect.