Drug Free Sport Staff Writers

Drug Free Sport Staff Writers

Friday, March 4, 2011

Methylhexaneamine (1, 3-dimethylamylamine) – UPDATE


What is Methylhexaneamine?

Why is Methylhexaneamine banned by some sport organizations?

·                Ginseng
·                Fish oils
·                Enzymes
·                DHEA and more

·         Geranium oil extract
·         Geranuim oil
·         Geranium extract
·         Geranamine (trademarked by Proviant Technologies)
·         Methylhexanamine
·         DMAA
·         Forthane
·         Forthan
·         Floradrene
·         4-methyl-2-hexanamine
·         4-Methylhexan-2-amine
·         2-amino-4-methylhexane
·         2-hexanamine, 4-methyl-
·         2-hexanamine, 4-methyl- (9CI)
·         1,3-dimethylamylamine
·         1,3-dimethylpentylamine
·         Pentylamine, 1, 3-dimethyl-


What products do you commonly find these ingredients listed in?
8.           CryoShock – Neogenix (1,3 Dimethylamylamine, caffeine)
10.       Motivate – Anabolic Innovations (1,3 Dimethylamylamine, caffeine)




  1. You are confused as to what Geranium oil is. It is not from the trace element, it is from Pelargonium graveolens (a flower that is also called rose geranium).

    This compound was studied intensively by a pharmaceutical company. It is about as safe as caffeine with an LD50 of 39mg/kg injected. Normal doses are 25-50 mg so that is only 0.5mg/kg.

    I can understand that dietary supplements being marketed to minors as a way to get ahead in sports can be concerning, but spreading fear via misinformation never helps.

  2. Amazing you say its as safe as caffeine. When I cycled off jack3d I had nothing but extreme withdrawals and paranoia.

    1. How long did your withdrawals and paranoia last?

    2. What were your symtoms? I believe i am going through extreme withdrawlss now. I have been to the hospital twice n have been diagnosed with virtigo n anxiety, i am 32 n until now i have never had either in my life. I had a similar reaction when i took a product called methyl test a couple of years ago but i only took it gor about 10 days before i had horrible/similar side effects n got off of it, i got better in just a couple of weeks. I have been taking jack 3d for months n have been off of it for over two weeks, i have never felt this sick in all of my life, sometimes feels like im dyin. Anyone else have these reactions?

    3. Justin, my son is going through the same thing. Our family is going crazy trying to find information relating to DMAA so that we can help him. He has been working out and taking supplements for two years (he was even sold these products under the age of 18 which I was not aware until recently). He assumed these were safe and natural. He stopped taking them completely a month ago and is having terrible anxiety, brain fog (as he describes it) and just not feeling right since he stopped. Some of the things he was taking that contained that ingredient were Jack 3D, C-4 Extreme and One More Rep. I see by your post that you stopped taking it around the same time. Please tell me how you are doing now and if there is something that you know more on this. Thank you.

    4. Hello, I just stopped taking the stuff and my mind is constantly spinning and trying to catch up with my eyes. I'm always dizzy and clogged up in my brain. How is your son?? Did it go away??

    5. If you don't cycle stimulants or take more than the recommended dosage, then of course you will have problems. Your son is most likely an idiot just like the rest of the ignorant sob's that misuse and abuse supplements and screw it up for the rest of us that actually take the time to learn about a supplement before ingesting it based on a recommendation by some college kid working at the local vitamin shop. You all have no one to blame but yourselves and your own ignorance. Read a book sometime, it does wonders.

    6. Not sure why you guys are having extreme withdrawals.. It's not crack! The only reason I can think that you may get withdrawals from, is taking it every day for more then 6 months. Its recommended you should be cycling on and off stimulants. 1. To stop a dependence from forming and 2. To stop your body from building a tolerance to it.....

  3. I want to attempt to clear things up for those that think we may be confused.

    Geranium oil extract is a common label name for methylhexanamine in supplement products. Methylhexaneamine has been shown to be naturally present in geranium oil at amounts less than 1%. This “natural” 1% is not what is being listed or included in supplement products on the market today. They are including higher amounts of methylhexaneamine and referencing ‘geranium oil’ to make the general public feel comfortable with its presence. The amounts included along with stimulants such as caffeine, synephrine, or even octopamine have caused a number of adverse reactions (including failed drug test) to date, as reported to the Resource Exchange Center:
    • Inability to “come down” from high
    • Heart palpitations
    • Increased blood pressure
    • Panic attacks
    • Failed drug test
    • Jitters
    We are not in the business of spreading fear, we simply want to help educate the public. In response to this statement:
    Supplement use by the general public is concerning, but especially concerning when they are marketed and sold to a demographic that no research at all has been done. I can assure you that our information is no misinformation with a great list of references:
    Lastly, we answer over 30,000 questions a year pertaining to dietary supplements, and work with a host of wonderful consultants, including:
    UCLA anylatical laboratory (WADA certified laboratory, started by renowned scientist Don Catlin)
    SMRTL anylatical laboratory (WADA certified laboratory)
    List of Pharmacist specializing in PED
    Gary Green (UCLA/MLB)
    Many more…
    So please understand, that methylhexanamine is the active ingredient that is of concern, and yes a small amount is present in geranium oil, but dietary supplement manufacturers are using higher amounts of methylhexanamine combined with other stimulants and listing it all under geranium oil at times. Dietary supplement manufacturers are not always truthful…

    1. Inability give it aroudn 5 hours and you will have extreme depression and anxiety when it wears off. Trust me ive used 1mr many a time. Everyone says the same thing. Try it yourself.

  4. Exelent Post !!!
    Thank you very much.
    I'm profesional rugby player in France.

  5. how long can Methylhexaneamine be detected after inadvertantly taken? days? months? years???
    I recently have been made aware of the banned substance. my competition isnt for a while, but am worried of how long it will stay in my stream. thanks

  6. Definition of half-life: The period in which the radioactivity or number of atoms of a radioactive substance decreases by half; similarly applied to any substance, such as a drug in serum, whose quantity decreases exponentially with time.(Stedmans Medical Dictionary)

    How long can Methylhexaneamine be detected? A number of factors must be considered...How much, how often, how potent the product was. When is your competition?

  7. not until September 2011.the product was oxyelite pro. I took the product for about a month and a half until middle of march. That was when I realized geranium root was illegal. thanks for your help

  8. sorry, that is supposed to be geranium stem. Also, not illegal, but banned.

  9. Does anyone know what this will show up as in a drug screen or do they have to test for this specific thing??????

    1. I have been taking jack3d and the original c4 for about a year now. I have to take monthly drug tests at a very big well known company and i pass them everytime. The only thing that i happens to me is that if i take after 3pm its harder for me to sleep at night.

    2. If you are not an athlete more than likely 1,3 Dimethylamylamine (aka - Methylhexaneamine, DMAA is not going to be part of the drug testing panel. This does not make you exempt from the possible adverse reactions associated with taking a supplement with multiple stimulants though.

  10. I believe it shows up as Methylhexanamine.

  11. I have read with great interest your posts on methyhexaneamine and its effects. I am unable to name, but a high profile athlete has recently tested positive in a drugs test for methylhexaneammine. It has been found the product (weught loss supplement) which was not meanr ro have it has been contaminated.

    Your forum seems to have knowledgeable individuals and I wondered if any were able to answer the following:

    1. Our product has 13.6% methylhexaneamine from the laboratory test results. this suggests not cross contamination but deliberately added?

    2. What are the known side effects short and long term that may be a result from accidental digestion, especially taken by a professional athlete?

    3. If a product was not meant to have methylhexaneamine and the manufacturer says none of their products contain it, how then can it enter a product?

    These questions have been asked to the company and legal action is underway which will become public shortly.

    thank you for any information and help

  12. I recently took a pre-workout supplement called Hemo Rage Black concentrate which has methylhexaneamine listed as an ingredient.
    I test regularly for a court ordered DUI program and they test for alcohol, etg's, and basically all illegal and controlled substances.
    I happened to take the Hemo Rage before working out on the morning I tested and the preliminary results of my test came back as positive for
    Since I don't use Methamphetamine or anything else that could be mistaken for it. ie: ephedrine, pseudoephedrine, etc. I am 100% sure that it was the methylhexaneamine that produced this result.
    I am currently awaiting laboratory results to confirm this for the courts, but in answer to your question. I can say with certainty that it CAN show up in tests as Methamphetamine.
    My question is how long will it stay in my system?

    1. i actually just got tested today and tested positive for a drug screen of amphetamine. Do the lab results still show use of amphetamines with the use of geranium extract?

  13. I am not sure of the protocols followed by your drug testing group, but I urge you become educated on the testing protocol. We only deal with sports drug testing so our protocols are very strict, even more so than court ordered drug testing. I suggest that you visit this website, http://chem.sis.nlm.nih.gov/chemidplus/, next type in Methamphetamine and look at the chemical structure. Now type in Methylhexaneamine and look at the structure. you will see that there is no relation or connection in my opinion, thus a positive drug test probably is not possible.

  14. I Regretfully, cannot answer all of these questions as they relate to a legal case, and the REC works with a number of professional organizations. Thank you for reading our blog and the compliments, but I do hope you understand our position.

  15. How long should the ban be for athletes caught with Methylhexaneamine in A and B samples? Do you know of any list that stipulates ban times for specific products? Thanks!

  16. You should check with your sport governing body and their drug policy to determine the answers to your questions. Every organization is different.

  17. This is very interesting.thank you

  18. Is there any way to neutralize Methylhexaneamine in body?

  19. how long does it take to leave your system?

    1. you should stop 24- 48 hours before comp day mate

  20. Robert Kendrick just got a 1-year ban from pro tennis for this stuff ... looks like it could quite likely have been inadvertent given the poor labeling standards, but nevertheless a cautionary tale if you are a competitive athlete.


  21. This is for the anonymous post that we recieved just a few days ago. I urge you to re-read the blog post before accusing us of not doing our research or spreading propaganda, we pride ourselves in being the best at what we do. Our post never mentions "germanium", but because the words share a number of the same letters we can understand the confussion.

  22. Great information and breakdown here. I don't mean to raise a ruckus but "Germanium" IS mentioned in the last sentence of the question in this post "So should I be worried if the label only lists Geranium oil and no other synonyms?" here: "Germanium is a nonessential trace element that has caused nephrotoxicity (kidney injury) and death when used chronically by humans, even at recommended levels of use."

    I'm not sure what Germanium, a metalloid, isotope-carrying elemental "rock" recently used in cancer fighting supplements, has to do with the Geranamine supplement discussion here? They're two different compounds with Germanium holding the nefarious title of death and kidney injury-- not Geranamine. As you mention, they're spelled similarly... but definitely not the same as it's confused in the included sentence above...

  23. I just got drug tested and tested positive for meth. I don't do any drugs at all and I don't smoke cigs. I work out a lot and started taking jack3d which has this substance in it. I don't take anything else at all. Is this product and substance the reason I tested positive?

  24. hi im taking c4 cellicor i just want to know if its dangerous for the body can any 1 help

  25. I work at a supplement shop and have going round and round with these companies on Geranium Root and Stem, Geranium Maculatum. Geranium Extract etc etc. The reality, after you have so graciously laid out to us is that IT'S ALL ABOUT THE DOSAGE!!! of geranium vs. the actual name or what part of the plant it's a derivative from.

  26. Hi, great information! Tho I'm a little confused. Is it safe to use this new supplement Hydroxy-stim? Please any information would be very appreciated, I've just started taking this supplement so I'm not seeing any effects yet. Thank so much!

  27. Very informative to know and definitely but understand. With that being said, is there anyway that someone could help me out with a quick synopsis or an overview for the C4 product. Sure this may produce incredible muscle gains strength and focus for some because everyone's body is different.. But overall I just want to know if it SAFE to use regardless of the fact if it banned for athletes. Thank you very much for this

  28. Hi, i am a personal trainer and have been taking jack3d for months. I take 1/2 to 3/4 of a scoop (which is less then the reconended dosage and now for the last two weeks have been having horrible symptoms. I have tried noxplode,black poweder, n many other supps, so i am no stanger to pre workoit supps but nothing has ever made me feel as bad as i do now. It started on my bday about 2 weeks ago with chest pain n shortness of breath, now i feel like my head is in a vice and am suffering from extreme virtigo. I have suffered brief moments of amnesia and also lose hearing in one of my ears occasionally,, i am getting very dizzy just typing these words and am trying to make it to a hospital tomorrow so i can find a doc who might know what is happebing to me, since the last doc i saw at the er didnt know n didnt seem to really care. I am 32 and hav never been this sick in my whole life. Has anyone else ever felt like this? I am done with supps for good. Fish oil n natural food only way to go. With all i hav learned of the unregulated supps for sale i want people to b aware of what they can do

    1. Please report this to the FDA adverse reporting webpage. These events must be documented.

    2. Wow I am 40 year male and consider myself in pretty good shape. About two weeks ago I started feeling sluggish,dizzy, loss of balance, and tighting of the chest, just pretty much like shit. I have been using jack3d off and on for over a year. After reading these statements It is starting to click what is wrong with me. Have a Cat-scan schedule because I have been having bad headaches on the left side of my head wonder if this is caused by the jack3d. I am done with that shit Hope I start feeling better. Glad i read this. Everybody stay healthy.

    3. I have just recently been feeling the same if u can please just update me on wat happened that would be well appreciated

  29. Is it dangerous to used these products to keep focus at work? Supposing you move around a lot on the job.

    my webpage: blog information

  31. How long does P6 extreme stay in your system?? Will you pass the dope test if you dont take it for a month. Will the testosterone levels come to normal?

  32. Does anyone actually know the dose of 1,3 Dimethylamylamine in OxyElite Pro or Jack3d. I went through a phase of feeling like I was dying when I came off Jack3d. It got me in the best shape of my life, then when I stopped it kicked my ass and I felt like I was being pulled out of my body. I called the ambulance a couple times but I got so paranoid and scared. I was smoking cigarettes and drinking at the time also so I quit both those things and eventually things returned to more of a normal state. I recently started taking OxyElite Pro (4 days ago) and have had mild jitters here and there but the workouts have been Great! I wonder how much of the 1,3 is in the prop blend. As to the people who have had issues with these supplements, it gets better after you stop.. I abused the hell out of my supplements. (put 2 scoops of Jack3d in a pint of beer once)... so I believe if you take less than the recommended dosage you;ll probably be fine. Drink Plenty of water, eat healthy etc... but ultimately, if you can do it without.. that's the way to Go! As far as getting that boost for workouts and all that.. Starbucks coffee isn't a bay way to go pre=workout.

  33. Joe - I think the best part of your post was, minus the "if" part, you can do it without (supplements)". These products are dietary supplements so the dosage of all ingredients can change from batch to batch, so using less of the recommend dosage is not a cure. Supplements can include unlisted ingredients that can cause adverse reactions. Thbe best pre-workout is to eat, hydrate, stretch and warm-up! Your warm-up is the bodys natural "boost".

  34. i have been taken fastin with methylsynephine in it and was wanting to know will i fail a drug test and if so i long does it take to get outta your system

  35. we get drug tested at work ramdon how long does this take to get out of your system? I'm worried now!

    1. depends on how much you take for how long and when you get tested. Work place they typically don't test for this though.

  36. I'm taking a thermo (Hydroxycut) before my work out. I only take 2 capsules but read the ingredients more carefully & notice this ingredient, 1,3,7-trimethylxanthine. Is this safe? Would this ingredient affect the result of a drug test?

  37. We had a comment come in that we did not post, but the poster said he did not know how anyone could have withdrawalsymptoms from a supplement...Well reason #1 DMAA was first produced as a drug (Forthane); and this is why the FDA has stepped in because drugs cannot be sold as dietary supplements.

  38. I took jacked for 2 years. 3 scoops everytime. I'm 190 lbs. I had 0 issues, and 0 withdrawals. Chemically, it would not test as meth, that's a lie. It's banned like all stimulants from competition, but so is a triple latte worth of caffeine. Always cycle off to prevent tolerance, know your body and for christs sake take care of your own kids, that's your fault.

  39. I accidentally drank just one serving of Hemo Rage,and I think I'll have dope test a month from now . I don't drink anything else.I am safe ? or how long does it take to leave your system?

  40. Rushmush (aurantiumamylamine)

    Similar to amphetamines

  41. Different than North American traditional sports enhancement aids, currently in the U.K a rare breed of fungus has hit the blackmarket for its unique amphetamine like profile of a substance called aurantiumamylamine, also known as ''RUSHMUSH''.

    RushMush is also common amongst night owls looking to dance the night away, as reported by the England Journal of independence. Frank Ashwater, a freelance writer has elicited interesting data from recreational users of this new novelty drug. Upon questioning some of the users of this mushroom, information that relates to it are as follows:

    Dosage= 1/2 gram to 1 gram
    Effects= Smooth agreeable stimulation similar to that of the amphetamines with a hint of cocaine,s central nervous system stimulanting effects

    Duration= 4-5 hours

    Rushmush mushrooms are like speed, but with a way better feeling, and way worse taste, one user explains.

  42. does anyone know if taking jack3d once to try will show up in the system? in general how long does a supplement take to leave the system?

  43. Have any one had experiences with Stacker4? Does this contain any banned ingredients?

  44. I took oxyelite pro for a couple of months and once I stopped I have been feeling dizzy/lightheaded for 3 months? I don't know what to do. I also feel tingling down my arms and legs. All my ct scan/mri's/ blood work have been negative. Anyone else experiencing this?

  45. I went to GNC yesterday to buy Aminolast from Gaspari and the owner of the GNC offered me some sample tasting of the Cellucor C4 Exteme and they tasted pretty good, so he gave me a few samples and said it would be good to use as pre-workout and that I would feel the difference in my runs, as soon as I take it. I'm a long distance runner. I tried half the packet (2 servings in a packet) was just wandering how bad this stuff is for you. I'm just an average runner, who runs 32-35 miles a week. We do have random drug tests at work and concerned about that too.

  46. Hi,

    First of all nice info here.
    I got 8 caps of Black Cats that contain 1,3 DMAA..
    I just emailled Applied Nutriceutical to ask how much of it does a cap of Black Cats contain.

    They replayed really fast. Its 20mg a cap..i searched on internet and 20mg is not a very high ammount.
    Is it oke to use that?
    bacause it gives me a good focus (i feel it) for studying. Amazing focus actually.

    I see alot of people complain about Jack 3D..well Jack 3D contains a very very high dosage of 1,3 DMMA
    Thats 142Mg!!

    here is the list (dont use this products!!)

    1. FlashOver --> 285mg (while the package says 20mg!!)
    2. OVERDOSE --> 217mg
    3. Jack3D --> 142mg

    all of these 3 are HEAVY dosage..if u have used this for months, you're fucked over.

    what 1M.R. concerned its 85mg.. its STRONG but not Heavy..

    But i use black cats and if Applied Nutriceutical company is not lying than its not so bad to use..i think! not sure!

    more info about the 1,3 DMAA dosage here --> geranamine.org



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  49. I am trying to educate myself on geranium oil as I found a weight loss supplement from Visi that contains it. Can anyone help me with it and let me know how safe it is. Thanks....

  50. I just c4 cellucor from gnc and was told by the employee this version of it does not have the questionable ingredient anymore. Is the current recipe safe?


  52. I took Oxi elite pro in late 2010 and again in 2011 briefly. Whenever I missed a dose or stopped taking it I felt like total crap. It is hard to describe. I just realized that stuff just isn't for me. I am doing research because ACE a new diet pill has it in it and I have an empty bottle of oxi elite pro and the geranium stem is in ACE. Bad news for me gonna stay away.

  53. I have been dizzy, nauseous, vertigo, headaches, visual disturbances, panic attacks. Used Jack3d for 2 years. Had every blood test you could think of and a MRI. All negative. Never felt so bad ever in my 28 years. It's been 3 months and I'm just starting to feel almost normal again. Never ever again will I take a pre-workout supp.