Paul Rutten

Paul did his undergraduate degree in Biochemistry at University College London, followed by a Masters in Systems and Synthetic Biology at Imperial College London. He is a DPhil student on the Interdisciplinary Bioscience DTP.

Paul’s work looks at the mechanisms controlling nitrogen regulation in symbiotic bacteria such as Rhizobium leguminosarum. A particular focus is how cells respond to changes in oxygen concentration, a key signal for nitrogen fixation in part because oxygen is toxic to the nitrogenase enzyme. Beyond understanding how these regulatory mechanisms function, the aim of his project is to modify them through Synthetic Biology approaches to build tools that can be used to engineer nitrogen fixation.

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In Oct 2018: DPhil Student, Year 3 of 4 years