Does circumferential tumor location affect the circumferential resection margin status in mid and low rectal cancer?

The purpose of this study was to assess the impact of circumferential tumor location on circumferential resection margin (CRM) status and the depth of tumor invasion in mid and low rectal cancer.

Comparison of biomarker expression between proximal and distal colorectal adenomas: The Tennessee–Indiana Adenoma Recurrence Study

It is unclear if proximal and distal traditional adenomas present with differences in molecular events which contribute to cancer heterogeneity by tumor anatomical subsite. Participants from a colonoscopy-based study (n = 380) were divided into subgroups based on the location of their most advanced adenoma: proximal, distal, or “equivalent both sides.”