Subjects carrying the ''G'' allele had a lower risk for stroke recurrence (relative risk, 0.71; P=0.002) than their wild-type carriers [R].

The age-related macular degeneration (AMD) risk was increased >3-fold for the ''A'' homozygotes compared with homozygous carriage of the ''G'' allele [R]. 

''G'' allele showed a statistically significant increased association with the risk of glioma (P = 0.006) [R]. 

Genotype GG+AG was significantly associated with overall survival of hepatocellular carcinoma (HCC) patients (P<0.001) [R]. 

GG genotype had a 1.6-fold higher risk for myocardial infarction (MI) (OR=1.6; p=0.022) [R].

The ''G'' allele was correlated with an increased risk of astrocytomas [R].

Advanced hepatocellular carcinoma patients treated with sorafenib harboring AA/AG genotype had a longer overall survival (OS) (13.0 vs 9.0 months, P=0.007) [R]. 


Parent Gene: KDR

Importance: 2
Less common allele: A = 50%
More common allele: G = 50%
My Genotype: Log In