TY - JOUR T1 - Archaeogenetic analysis of Neolithic sheep from Anatolia suggests a complex demographic history since domestication JF - bioRxiv DO - 10.1101/2020.04.17.033415 SP - 2020.04.17.033415 AU - Yurtman, Erinç AU - Özer, Onur AU - Yüncü, Eren AU - Dağtaş, Nihan Dilşad AU - Koptekin, Dilek AU - Çakan, Yasin Gökhan AU - Özkan, Mustafa AU - Akbaba, Ali AU - Kaptan, Damla AU - Atağ, Gözde AU - Vural, Kıvılcım Başak AU - Gündem, Can Yümni AU - Martin, Louise AU - Kılınç, Gülşah Merve AU - Ghalichi, Ayshin AU - Açan, Sinan Can AU - Yaka, Reyhan AU - Sağlıcan, Ekin AU - Lagerholm, Vendela Kempe AU - Krzewinska, Maja AU - Pişkin, Evangelia AU - Şevketoğlu, Müge AU - Bilgin, C. Can AU - Atakuman, Çiğdem AU - Erdal, Yılmaz Selim AU - Sürer, Elif AU - Lenstra, Johannes AU - Yorulmaz, Sevgi AU - Abazari, Foad AU - Hoseinzadeh, Javad AU - Baird, Douglas AU - Bıçakçı, Erhan AU - Çevik, Özlem AU - Gerritsen, Fokke AU - Özbal, Rana AU - Götherström, Anders AU - Somel, Mehmet AU - Togan, İnci AU - Özer, Füsun Y1 - 2020/01/01 UR - http://biorxiv.org/content/early/2020/04/18/2020.04.17.033415.abstract N2 - Sheep was among the first domesticated animals, but its demographic history is little understood. Here we present combined analyses of mitochondrial and nuclear polymorphism data from ancient central and west Anatolian sheep dating to the Late Glacial and early Holocene. We observe loss of mitochondrial haplotype diversity around 7500 BCE during the early Neolithic, consistent with a domestication-related bottleneck. Post-7000 BCE, mitochondrial haplogroup diversity increases, compatible with admixture from other domestication centres and/or from wild populations. Analysing archaeogenomic data, we further find that Anatolian Neolithic sheep (ANS) are genetically closest to present-day European breeds, and especially those from central and north Europe. Our results indicate that Asian contribution to south European breeds in the post-Neolithic era, possibly during the Bronze Age, may explain this pattern.Competing Interest StatementThe authors have declared no competing interest. ER -