1 Tube, 1 Week, Comprehensive Molecular Results for Cancer Patients

DNA, RNA, MSI and PD-L1 | Somatic and Hereditary

Your genes, right now.

CIRCULOGENE’s molecular diagnostics process is based on the discovery that as tumor cells multiply, they also die, releasing their DNA into the bloodstream. CIRCULOGENE’s comprehensive tumor DNA sequencing is the only testing available that combines minimal volumes of blood with the most advanced next-generation sequencing (NGS) to monitor tumor-mutant DNA within well-characterized, well-documented, cancer-associated genes.

With just one tube of blood, CIRCULOGENE’s patented technology utilizes NGS to monitor thousands of known tumor mutations across multiple cancer-associated genes, providing the most comprehensive information on current FDA-approved treatment options.


Minimal-volume input with maximal yield. One tube for the full range of DNA, RNA, and MSI immunotherapy testing means access to a patient’s blood is even less invasive.


Proprietary, direct-on-specimen enrichment technology locates and captures cell-free DNA, identifying and quantifying any tumor mutations for accurate reporting and monitoring.


Capable of testing more than 50 genes for approximately 3,000 possible mutations. Multi-mutation monitoring capabilities encompass a broad range of tumor profiles and allow for rapid-turnaround, patient-centered, precision medicine.


Because our patented technique enriches the sample, CIRCULOGENE analysis requires only one tube of blood, which is more convenient for health care professionals and patients.
CIRCULOGENE’s tests analyze for the presence of cell-free DNA, identifying and quantifying any tumor mutations for accurate reporting and monitoring.
In our personalized gene reports, CIRCULOGENE further provides information on current FDA-approved treatment options proven effective for the tumor DNA mutations identified.
The efficiency of CIRCULOGENE’s process empowers physicians to closely monitor tumor responsiveness and adjust treatment protocols. Turnaround time is five to seven days, much faster than tissue biopsy results and other liquid biopsies.
The CIRCULOGENE process uses precise baseline data from which to measure cell turnover and progression.
We compared the sensitivity of our proprietary cell-free DNA enrichment method to the standard DNA extraction kit used industry-wide today. Results demonstrated 100x more cell-free tumor DNA in the original sample using a single tube of blood.

CAP NUMBER: 9373166
The College of American Pathologists

CLIA NUMBER: 01D2101075
Clinical Laboratory Improvement Amendments (CLIA)


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Sample Report Overview

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Contact Us

3125 Independence Drive
Suite 301
Birmingham, AL 35209