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gemini-1.5-flash-preview-0514
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gemini-1.5-flash-preview-0514
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Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Summarize the four different views of Judaism held today based on the information found below.
Judaism today is descended from Rabbinic Judaism, that is, the Judaism that emerged after the destruction of the second temple by the Romans in 70 ce. This form of Judaism was centered around the Torah and the synagogue, instead of the temple. From the first century ce until the nineteenth century, there was basically only one way of being Jewish, and for the most part, by choice or not, it consisted of a life lived separated from the larger society.
With the growing secularization in nineteenth-century Western Europe, however, Jews became more active participants in “secular” society, even while maintaining their “sacred” practices and beliefs. Different interpretations of Judaism developed that guided the interplay between these sacred and secular worlds. Over time, these differences resulted in the four main branches of Judaism that exist today.
Orthodox Judaism is the modern term for what historically has been mainline Judaism: in other words, before the nineteenth century, Orthodox Judaism was Judaism, plain and simple. It is based on an understanding of the Torah as the unchangeable, inerrant revelation of God that provides the sole guide for all aspects of one’s daily life. Accordingly, Orthodox Jews meticulously observe Jewish law, that is, halakhah (literally “the way one walks”), which is based on an understanding that all 613 commandments within the Torah have been revealed as the direct, immutable will of God.
Reform Judaism emerged during the Enlightenment as some sought to “reform” Jewish thought and practice in light of new scientific developments, political ideas, and modernism. While Orthodox Judaism considers the Torah the unchanging divine command of God, Reform Judaism sees the Torah as written by “divinely inspired” human authors. The Torah—and the commandments therein—is regarded as instructional and inspirational, but not absolutely binding. Reform Judaism emphasizes obligation to the neighbor, care for the world, and the injunction to offer hospitality and care to all in need. All other aspects of Judaism are open to negotiation.
Conservative Judaism was founded as a response to what were viewed as overly radical changes in Reform Judaism: it was believed that while change was needed, Reform Judaism had moved too far too quickly. Conservative Judaism emphasizes on ritual practice, rather than specific doctrines. One of the distinguishing marks of Conservative Judaism, as opposed to Reform Judaism, is its preservation of the halakhic process when deciding how traditional interpretation of Jewish law might be changed. In that process, rabbis consult sacred scriptures and commentaries, rabbinic codes of law, and previous generations of rabbinical opinion, in order to craft a new reading for today.
Reconstructionist Judaism is the most recent to emerge. It holds that what is important about Judaism is not that everyone believes the same things about divine revelation, miracles, and God, or that people follow Jewish law in the same way. Instead, it sees the value of Judaism first as a cultural force uniting, supporting, and nurturing the Jewish people over time and space. As such, everything is open to debate and modification—all beliefs, all doctrines, all practices—according to the current needs of the Jewish community. Tradition is important as a way of maintaining community, but it has only a voice, not a veto—and, of course, there are many different views about how much of a vote tradition should have in any specific decision about Jewish life.
Response: Rabbinic Judaism, which emerged after 70 CE, focused on the Torah and the synagogue, instead of the temple. Nineteenth-century secularism resulted in the separation of four main branches of Judaism.
Orthodox Judaism believes that the Torah is the unchangeable, inerrant revelation of God and is the sole guide for daily life. As such, Orthodox Jews methodically follow Jewish law and the 613 commandments within the Torah.
Reform Judaism sees the Torah as written by “divinely inspired” human authors and uses it as instruction and inspiration that is open to negotiation.
Conservative Judaism, a response to Reform Judaism, emphasizes ritual practice over doctrines but uses rabbinic law and opinion, sacred scriptures, and commentaries, to craft change to traditional practices.
Reconstructionist Judaism, the latest to emerge, holds that not everyone has the same beliefs about divine revelation or Jewish law and that as a result everything is open to debate and modification, Judaism’s value is a cultural force that unites, supports, and nurtures the Jewish people.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Summarize the main points of the book 'The Power of Habit' by outlining the author's key arguments regarding habit formation, the habit loop, and strategies for changing habits.",
"role": "user"
},
{
"content": "'The Power of Habit' by Charles Duhigg explores the science behind habit formation and provides insights into how habits are formed, maintained, and changed. The book introduces the 'habit loop', a three-part process that includes cue, routine, and reward, and emphasizes the importance of understanding this loop to effectively modify existing habits or develop new ones. Duhigg presents strategies for breaking old habits and building new ones, highlighting the role of willpower, environmental cues, and the power of rewards in habit change.",
"role": "assistant"
}
] |
Summarization
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gemini-1.5-flash-preview-0514
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gemini-1.5-flash-preview-0514
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Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Summarize the four different views of Judaism held today based on the information found below.
Judaism today is descended from Rabbinic Judaism, that is, the Judaism that emerged after the destruction of the second temple by the Romans in 70 ce. This form of Judaism was centered around the Torah and the synagogue, instead of the temple. From the first century ce until the nineteenth century, there was basically only one way of being Jewish, and for the most part, by choice or not, it consisted of a life lived separated from the larger society.
With the growing secularization in nineteenth-century Western Europe, however, Jews became more active participants in “secular” society, even while maintaining their “sacred” practices and beliefs. Different interpretations of Judaism developed that guided the interplay between these sacred and secular worlds. Over time, these differences resulted in the four main branches of Judaism that exist today.
Orthodox Judaism is the modern term for what historically has been mainline Judaism: in other words, before the nineteenth century, Orthodox Judaism was Judaism, plain and simple. It is based on an understanding of the Torah as the unchangeable, inerrant revelation of God that provides the sole guide for all aspects of one’s daily life. Accordingly, Orthodox Jews meticulously observe Jewish law, that is, halakhah (literally “the way one walks”), which is based on an understanding that all 613 commandments within the Torah have been revealed as the direct, immutable will of God.
Reform Judaism emerged during the Enlightenment as some sought to “reform” Jewish thought and practice in light of new scientific developments, political ideas, and modernism. While Orthodox Judaism considers the Torah the unchanging divine command of God, Reform Judaism sees the Torah as written by “divinely inspired” human authors. The Torah—and the commandments therein—is regarded as instructional and inspirational, but not absolutely binding. Reform Judaism emphasizes obligation to the neighbor, care for the world, and the injunction to offer hospitality and care to all in need. All other aspects of Judaism are open to negotiation.
Conservative Judaism was founded as a response to what were viewed as overly radical changes in Reform Judaism: it was believed that while change was needed, Reform Judaism had moved too far too quickly. Conservative Judaism emphasizes on ritual practice, rather than specific doctrines. One of the distinguishing marks of Conservative Judaism, as opposed to Reform Judaism, is its preservation of the halakhic process when deciding how traditional interpretation of Jewish law might be changed. In that process, rabbis consult sacred scriptures and commentaries, rabbinic codes of law, and previous generations of rabbinical opinion, in order to craft a new reading for today.
Reconstructionist Judaism is the most recent to emerge. It holds that what is important about Judaism is not that everyone believes the same things about divine revelation, miracles, and God, or that people follow Jewish law in the same way. Instead, it sees the value of Judaism first as a cultural force uniting, supporting, and nurturing the Jewish people over time and space. As such, everything is open to debate and modification—all beliefs, all doctrines, all practices—according to the current needs of the Jewish community. Tradition is important as a way of maintaining community, but it has only a voice, not a veto—and, of course, there are many different views about how much of a vote tradition should have in any specific decision about Jewish life.
Response: Rabbinic Judaism, which emerged after 70 CE, focused on the Torah and the synagogue, instead of the temple. Nineteenth-century secularism resulted in the separation of four main branches of Judaism.
Orthodox Judaism believes that the Torah is the unchangeable, inerrant revelation of God and is the sole guide for daily life. As such, Orthodox Jews methodically follow Jewish law and the 613 commandments within the Torah.
Reform Judaism sees the Torah as written by “divinely inspired” human authors and uses it as instruction and inspiration that is open to negotiation.
Conservative Judaism, a response to Reform Judaism, emphasizes ritual practice over doctrines but uses rabbinic law and opinion, sacred scriptures, and commentaries, to craft change to traditional practices.
Reconstructionist Judaism, the latest to emerge, holds that not everyone has the same beliefs about divine revelation or Jewish law and that as a result everything is open to debate and modification, Judaism’s value is a cultural force that unites, supports, and nurtures the Jewish people.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Summarize the main arguments presented in the article 'The Role of Technology in Education' by analyzing the key points regarding the use of technology for personalized learning, collaborative projects, and access to information.",
"role": "user"
},
{
"content": "The article 'The Role of Technology in Education' explores the transformative potential of technology in education. It highlights how technology can personalize learning experiences by providing tailored content and adaptive assessments. The article also discusses the role of technology in facilitating collaborative projects, enabling students to work together and share ideas remotely. Finally, it emphasizes the access to vast information resources that technology provides, empowering students to become independent learners.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Summarize the four different views of Judaism held today based on the information found below.
Judaism today is descended from Rabbinic Judaism, that is, the Judaism that emerged after the destruction of the second temple by the Romans in 70 ce. This form of Judaism was centered around the Torah and the synagogue, instead of the temple. From the first century ce until the nineteenth century, there was basically only one way of being Jewish, and for the most part, by choice or not, it consisted of a life lived separated from the larger society.
With the growing secularization in nineteenth-century Western Europe, however, Jews became more active participants in “secular” society, even while maintaining their “sacred” practices and beliefs. Different interpretations of Judaism developed that guided the interplay between these sacred and secular worlds. Over time, these differences resulted in the four main branches of Judaism that exist today.
Orthodox Judaism is the modern term for what historically has been mainline Judaism: in other words, before the nineteenth century, Orthodox Judaism was Judaism, plain and simple. It is based on an understanding of the Torah as the unchangeable, inerrant revelation of God that provides the sole guide for all aspects of one’s daily life. Accordingly, Orthodox Jews meticulously observe Jewish law, that is, halakhah (literally “the way one walks”), which is based on an understanding that all 613 commandments within the Torah have been revealed as the direct, immutable will of God.
Reform Judaism emerged during the Enlightenment as some sought to “reform” Jewish thought and practice in light of new scientific developments, political ideas, and modernism. While Orthodox Judaism considers the Torah the unchanging divine command of God, Reform Judaism sees the Torah as written by “divinely inspired” human authors. The Torah—and the commandments therein—is regarded as instructional and inspirational, but not absolutely binding. Reform Judaism emphasizes obligation to the neighbor, care for the world, and the injunction to offer hospitality and care to all in need. All other aspects of Judaism are open to negotiation.
Conservative Judaism was founded as a response to what were viewed as overly radical changes in Reform Judaism: it was believed that while change was needed, Reform Judaism had moved too far too quickly. Conservative Judaism emphasizes on ritual practice, rather than specific doctrines. One of the distinguishing marks of Conservative Judaism, as opposed to Reform Judaism, is its preservation of the halakhic process when deciding how traditional interpretation of Jewish law might be changed. In that process, rabbis consult sacred scriptures and commentaries, rabbinic codes of law, and previous generations of rabbinical opinion, in order to craft a new reading for today.
Reconstructionist Judaism is the most recent to emerge. It holds that what is important about Judaism is not that everyone believes the same things about divine revelation, miracles, and God, or that people follow Jewish law in the same way. Instead, it sees the value of Judaism first as a cultural force uniting, supporting, and nurturing the Jewish people over time and space. As such, everything is open to debate and modification—all beliefs, all doctrines, all practices—according to the current needs of the Jewish community. Tradition is important as a way of maintaining community, but it has only a voice, not a veto—and, of course, there are many different views about how much of a vote tradition should have in any specific decision about Jewish life.
Response: Rabbinic Judaism, which emerged after 70 CE, focused on the Torah and the synagogue, instead of the temple. Nineteenth-century secularism resulted in the separation of four main branches of Judaism.
Orthodox Judaism believes that the Torah is the unchangeable, inerrant revelation of God and is the sole guide for daily life. As such, Orthodox Jews methodically follow Jewish law and the 613 commandments within the Torah.
Reform Judaism sees the Torah as written by “divinely inspired” human authors and uses it as instruction and inspiration that is open to negotiation.
Conservative Judaism, a response to Reform Judaism, emphasizes ritual practice over doctrines but uses rabbinic law and opinion, sacred scriptures, and commentaries, to craft change to traditional practices.
Reconstructionist Judaism, the latest to emerge, holds that not everyone has the same beliefs about divine revelation or Jewish law and that as a result everything is open to debate and modification, Judaism’s value is a cultural force that unites, supports, and nurtures the Jewish people.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Summarize the key points of the speech 'The Importance of Diversity and Inclusion' by identifying the main arguments regarding the benefits of a diverse and inclusive society.",
"role": "user"
},
{
"content": "The speech 'The Importance of Diversity and Inclusion' advocates for the creation of a society that embraces diversity and promotes inclusion. The speaker highlights the benefits of a diverse society, including greater creativity, innovation, and problem-solving capabilities. The speech emphasizes the importance of fostering an inclusive environment where all individuals feel valued, respected, and have equal opportunities to participate and contribute.",
"role": "assistant"
}
] |
Summarization
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gemini-1.5-flash-preview-0514
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gemini-1.5-flash-preview-0514
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Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Summarize the four different views of Judaism held today based on the information found below.
Judaism today is descended from Rabbinic Judaism, that is, the Judaism that emerged after the destruction of the second temple by the Romans in 70 ce. This form of Judaism was centered around the Torah and the synagogue, instead of the temple. From the first century ce until the nineteenth century, there was basically only one way of being Jewish, and for the most part, by choice or not, it consisted of a life lived separated from the larger society.
With the growing secularization in nineteenth-century Western Europe, however, Jews became more active participants in “secular” society, even while maintaining their “sacred” practices and beliefs. Different interpretations of Judaism developed that guided the interplay between these sacred and secular worlds. Over time, these differences resulted in the four main branches of Judaism that exist today.
Orthodox Judaism is the modern term for what historically has been mainline Judaism: in other words, before the nineteenth century, Orthodox Judaism was Judaism, plain and simple. It is based on an understanding of the Torah as the unchangeable, inerrant revelation of God that provides the sole guide for all aspects of one’s daily life. Accordingly, Orthodox Jews meticulously observe Jewish law, that is, halakhah (literally “the way one walks”), which is based on an understanding that all 613 commandments within the Torah have been revealed as the direct, immutable will of God.
Reform Judaism emerged during the Enlightenment as some sought to “reform” Jewish thought and practice in light of new scientific developments, political ideas, and modernism. While Orthodox Judaism considers the Torah the unchanging divine command of God, Reform Judaism sees the Torah as written by “divinely inspired” human authors. The Torah—and the commandments therein—is regarded as instructional and inspirational, but not absolutely binding. Reform Judaism emphasizes obligation to the neighbor, care for the world, and the injunction to offer hospitality and care to all in need. All other aspects of Judaism are open to negotiation.
Conservative Judaism was founded as a response to what were viewed as overly radical changes in Reform Judaism: it was believed that while change was needed, Reform Judaism had moved too far too quickly. Conservative Judaism emphasizes on ritual practice, rather than specific doctrines. One of the distinguishing marks of Conservative Judaism, as opposed to Reform Judaism, is its preservation of the halakhic process when deciding how traditional interpretation of Jewish law might be changed. In that process, rabbis consult sacred scriptures and commentaries, rabbinic codes of law, and previous generations of rabbinical opinion, in order to craft a new reading for today.
Reconstructionist Judaism is the most recent to emerge. It holds that what is important about Judaism is not that everyone believes the same things about divine revelation, miracles, and God, or that people follow Jewish law in the same way. Instead, it sees the value of Judaism first as a cultural force uniting, supporting, and nurturing the Jewish people over time and space. As such, everything is open to debate and modification—all beliefs, all doctrines, all practices—according to the current needs of the Jewish community. Tradition is important as a way of maintaining community, but it has only a voice, not a veto—and, of course, there are many different views about how much of a vote tradition should have in any specific decision about Jewish life.
Response: Rabbinic Judaism, which emerged after 70 CE, focused on the Torah and the synagogue, instead of the temple. Nineteenth-century secularism resulted in the separation of four main branches of Judaism.
Orthodox Judaism believes that the Torah is the unchangeable, inerrant revelation of God and is the sole guide for daily life. As such, Orthodox Jews methodically follow Jewish law and the 613 commandments within the Torah.
Reform Judaism sees the Torah as written by “divinely inspired” human authors and uses it as instruction and inspiration that is open to negotiation.
Conservative Judaism, a response to Reform Judaism, emphasizes ritual practice over doctrines but uses rabbinic law and opinion, sacred scriptures, and commentaries, to craft change to traditional practices.
Reconstructionist Judaism, the latest to emerge, holds that not everyone has the same beliefs about divine revelation or Jewish law and that as a result everything is open to debate and modification, Judaism’s value is a cultural force that unites, supports, and nurtures the Jewish people.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Summarize the main themes explored in the novel 'Pride and Prejudice' by focusing on the key themes of love, marriage, social class, and individual growth.",
"role": "user"
},
{
"content": "The novel 'Pride and Prejudice' by Jane Austen explores themes of love, marriage, social class, and individual growth. The story follows the lives of the Bennet sisters as they navigate the complexities of courtship and marriage in 19th-century England. The novel delves into the societal pressures surrounding marriage, the importance of social standing, and the individual journey of self-discovery and personal development.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Summarize the four different views of Judaism held today based on the information found below.
Judaism today is descended from Rabbinic Judaism, that is, the Judaism that emerged after the destruction of the second temple by the Romans in 70 ce. This form of Judaism was centered around the Torah and the synagogue, instead of the temple. From the first century ce until the nineteenth century, there was basically only one way of being Jewish, and for the most part, by choice or not, it consisted of a life lived separated from the larger society.
With the growing secularization in nineteenth-century Western Europe, however, Jews became more active participants in “secular” society, even while maintaining their “sacred” practices and beliefs. Different interpretations of Judaism developed that guided the interplay between these sacred and secular worlds. Over time, these differences resulted in the four main branches of Judaism that exist today.
Orthodox Judaism is the modern term for what historically has been mainline Judaism: in other words, before the nineteenth century, Orthodox Judaism was Judaism, plain and simple. It is based on an understanding of the Torah as the unchangeable, inerrant revelation of God that provides the sole guide for all aspects of one’s daily life. Accordingly, Orthodox Jews meticulously observe Jewish law, that is, halakhah (literally “the way one walks”), which is based on an understanding that all 613 commandments within the Torah have been revealed as the direct, immutable will of God.
Reform Judaism emerged during the Enlightenment as some sought to “reform” Jewish thought and practice in light of new scientific developments, political ideas, and modernism. While Orthodox Judaism considers the Torah the unchanging divine command of God, Reform Judaism sees the Torah as written by “divinely inspired” human authors. The Torah—and the commandments therein—is regarded as instructional and inspirational, but not absolutely binding. Reform Judaism emphasizes obligation to the neighbor, care for the world, and the injunction to offer hospitality and care to all in need. All other aspects of Judaism are open to negotiation.
Conservative Judaism was founded as a response to what were viewed as overly radical changes in Reform Judaism: it was believed that while change was needed, Reform Judaism had moved too far too quickly. Conservative Judaism emphasizes on ritual practice, rather than specific doctrines. One of the distinguishing marks of Conservative Judaism, as opposed to Reform Judaism, is its preservation of the halakhic process when deciding how traditional interpretation of Jewish law might be changed. In that process, rabbis consult sacred scriptures and commentaries, rabbinic codes of law, and previous generations of rabbinical opinion, in order to craft a new reading for today.
Reconstructionist Judaism is the most recent to emerge. It holds that what is important about Judaism is not that everyone believes the same things about divine revelation, miracles, and God, or that people follow Jewish law in the same way. Instead, it sees the value of Judaism first as a cultural force uniting, supporting, and nurturing the Jewish people over time and space. As such, everything is open to debate and modification—all beliefs, all doctrines, all practices—according to the current needs of the Jewish community. Tradition is important as a way of maintaining community, but it has only a voice, not a veto—and, of course, there are many different views about how much of a vote tradition should have in any specific decision about Jewish life.
Response: Rabbinic Judaism, which emerged after 70 CE, focused on the Torah and the synagogue, instead of the temple. Nineteenth-century secularism resulted in the separation of four main branches of Judaism.
Orthodox Judaism believes that the Torah is the unchangeable, inerrant revelation of God and is the sole guide for daily life. As such, Orthodox Jews methodically follow Jewish law and the 613 commandments within the Torah.
Reform Judaism sees the Torah as written by “divinely inspired” human authors and uses it as instruction and inspiration that is open to negotiation.
Conservative Judaism, a response to Reform Judaism, emphasizes ritual practice over doctrines but uses rabbinic law and opinion, sacred scriptures, and commentaries, to craft change to traditional practices.
Reconstructionist Judaism, the latest to emerge, holds that not everyone has the same beliefs about divine revelation or Jewish law and that as a result everything is open to debate and modification, Judaism’s value is a cultural force that unites, supports, and nurtures the Jewish people.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Summarize the key points of the research article 'The Impact of Social Media on Mental Health' by identifying the main findings regarding the relationship between social media use and anxiety, depression, and body image concerns.",
"role": "user"
},
{
"content": "The research article 'The Impact of Social Media on Mental Health' investigates the relationship between social media use and mental health. The study found a correlation between excessive social media use and increased levels of anxiety, depression, and body image concerns. The article highlights the potential negative effects of social comparison, cyberbullying, and the constant pressure to present an idealized online persona on mental well-being.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Summarize the four different views of Judaism held today based on the information found below.
Judaism today is descended from Rabbinic Judaism, that is, the Judaism that emerged after the destruction of the second temple by the Romans in 70 ce. This form of Judaism was centered around the Torah and the synagogue, instead of the temple. From the first century ce until the nineteenth century, there was basically only one way of being Jewish, and for the most part, by choice or not, it consisted of a life lived separated from the larger society.
With the growing secularization in nineteenth-century Western Europe, however, Jews became more active participants in “secular” society, even while maintaining their “sacred” practices and beliefs. Different interpretations of Judaism developed that guided the interplay between these sacred and secular worlds. Over time, these differences resulted in the four main branches of Judaism that exist today.
Orthodox Judaism is the modern term for what historically has been mainline Judaism: in other words, before the nineteenth century, Orthodox Judaism was Judaism, plain and simple. It is based on an understanding of the Torah as the unchangeable, inerrant revelation of God that provides the sole guide for all aspects of one’s daily life. Accordingly, Orthodox Jews meticulously observe Jewish law, that is, halakhah (literally “the way one walks”), which is based on an understanding that all 613 commandments within the Torah have been revealed as the direct, immutable will of God.
Reform Judaism emerged during the Enlightenment as some sought to “reform” Jewish thought and practice in light of new scientific developments, political ideas, and modernism. While Orthodox Judaism considers the Torah the unchanging divine command of God, Reform Judaism sees the Torah as written by “divinely inspired” human authors. The Torah—and the commandments therein—is regarded as instructional and inspirational, but not absolutely binding. Reform Judaism emphasizes obligation to the neighbor, care for the world, and the injunction to offer hospitality and care to all in need. All other aspects of Judaism are open to negotiation.
Conservative Judaism was founded as a response to what were viewed as overly radical changes in Reform Judaism: it was believed that while change was needed, Reform Judaism had moved too far too quickly. Conservative Judaism emphasizes on ritual practice, rather than specific doctrines. One of the distinguishing marks of Conservative Judaism, as opposed to Reform Judaism, is its preservation of the halakhic process when deciding how traditional interpretation of Jewish law might be changed. In that process, rabbis consult sacred scriptures and commentaries, rabbinic codes of law, and previous generations of rabbinical opinion, in order to craft a new reading for today.
Reconstructionist Judaism is the most recent to emerge. It holds that what is important about Judaism is not that everyone believes the same things about divine revelation, miracles, and God, or that people follow Jewish law in the same way. Instead, it sees the value of Judaism first as a cultural force uniting, supporting, and nurturing the Jewish people over time and space. As such, everything is open to debate and modification—all beliefs, all doctrines, all practices—according to the current needs of the Jewish community. Tradition is important as a way of maintaining community, but it has only a voice, not a veto—and, of course, there are many different views about how much of a vote tradition should have in any specific decision about Jewish life.
Response: Rabbinic Judaism, which emerged after 70 CE, focused on the Torah and the synagogue, instead of the temple. Nineteenth-century secularism resulted in the separation of four main branches of Judaism.
Orthodox Judaism believes that the Torah is the unchangeable, inerrant revelation of God and is the sole guide for daily life. As such, Orthodox Jews methodically follow Jewish law and the 613 commandments within the Torah.
Reform Judaism sees the Torah as written by “divinely inspired” human authors and uses it as instruction and inspiration that is open to negotiation.
Conservative Judaism, a response to Reform Judaism, emphasizes ritual practice over doctrines but uses rabbinic law and opinion, sacred scriptures, and commentaries, to craft change to traditional practices.
Reconstructionist Judaism, the latest to emerge, holds that not everyone has the same beliefs about divine revelation or Jewish law and that as a result everything is open to debate and modification, Judaism’s value is a cultural force that unites, supports, and nurtures the Jewish people.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Summarize the key arguments presented in the essay 'The Future of Artificial Intelligence' by analyzing the main points regarding the potential benefits and risks of AI development.",
"role": "user"
},
{
"content": "The essay 'The Future of Artificial Intelligence' explores the potential benefits and risks associated with the development of artificial intelligence. The author highlights the transformative potential of AI in various fields, including healthcare, transportation, and scientific research. However, the essay also emphasizes the ethical and societal implications of AI, raising concerns about job displacement, algorithmic bias, and the potential for misuse of AI technology.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Tell me about crizotinib.
Abstract
Anaplastic lymphoma kinase (ALK) gene rearrangements are present in a small subset of non-small-cell lung cancers. ALK-positivity confers sensitivity to small-molecule ALK kinase inhibitors, such as crizotinib. The integration of crizotinib into standard treatment practice in NSCLC will rest on the widespread implementation of an effective screening system for newly diagnosed patients with NSCLC which is flexible enough to incorporate new targets as treatments are developed for them. Phase I and II studies of crizotinib in ALK-positive lung cancer have demonstrated significant activity and impressive clinical benefit, which led to its early approval by USFDA in 2011. Although crizotinib induces remissions and extends the lives of patients, there have been reports of emerging resistance to Crizotinib therapy. In this review, we discuss the history, mechanism of action, uses, adverse effects, dose modifications and future challenges and opportunities for patients with ALK-positive lung cancers.
Keywords: ALK mutation, ALK inhibitors, ALK positive Non-small cell lung cancer, Crizotinib
Overview of Clinical Trials
The antitumor efficacy of crizotinib was initially demonstrated in two multicenter, single-arm studies.[23,24] Dosage for these extended series was 250 mg, orally, given twice a day, based on results from the initial phase I dose escalation study. In aggregate, these studies included 255 patients, all of whose tumors contained an ALK gene rearrangement, as shown by FISH. Overall, 95% of the patients had metastatic disease and 5% had locally advanced NSCLC. Overall, 94% of the patients had received prior systemic therapy for advanced or metastatic disease, and 76% had received two or more treatment regimens. The combined objective (complete plus partial) response rate was 55%, the majority of which was achieved during the first eight weeks of treatment. The median durations of response at the time of analysis of the two studies were 42 and 48 weeks, respectively [Table 1].
Table 1
Comparison of results of profile 1001 and profile 1005 trials
An external file that holds a picture, illustration, etc.
Object name is SAJC-2-91-g003.jpg
Evidence of the impact of crizotinib on the survival of patients came from a non-randomized, retrospective analysis of the patients enrolled in the phase I study.[25] The one- and two-year survival rates for patients treated with crizotinib were 74 and 54%, respectively, with a median follow-up of 18 months. In a cohort of 36 patients with the ALK fusion oncogene, who were not treated with crizotinib, the survival rates at one- and two-years were 44 and 12%, respectively. A comparison with a larger cohort of patients with wild-type tumors did not identify a difference when compared with those with the ALK rearrangement not treated with crizotinib, suggesting that the presence of ALK rearrangement was not prognostically significant.
Conclusions
The presence of an ALK fusion oncogene defines a molecular subset of NSCLC with distinct clinical and pathological features. The patients most likely to harbor ALK rearrangement are relatively young, never or light smokers with adenocarcinoma. Whenever possible, therapy of patients with advanced NSCLC should be individualized, based on the molecular and histological features of the tumor. If feasible, patients should have the tumor tissue assessed for the presence of a somatic mutation in the EGFR, which confers sensitivity to the EGFR tyrosine kinase inhibitors and to the ALK fusion oncogene, which is associated with sensitivity to crizotinib.
Thus, crizotinib is an important unmet medical need. It is a straightforward, biology-based biomarker, predicting a high response rate in heavily pre-treated patients and is relatively non-toxic. It is a triumph for a targeted therapy in the era of oncogenic driver mutations.
Response: Crizotinib is a small-molecule anaplastic lymphoma kinase (ALK) inhibitor that can be used to induce remission in non-small-cell lung cancers or NSCLC when ALK mutations are present.
In a non-randomized, retrospective analysis from a phase 1 study, crizotinib was found to improve one to two-year survival rates for patients from 44-12% to 74-54%.
Crizotinib has been shown to be a relatively non-toxic biomarker that has accomplished successful targeted therapy for people with a somatic mutation of the EGFR who have sensitivity to the ALK fusion oncogene although it remains an unmet medical need.
There have been reports of increased resistance to crizotinib which may require further research.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Explain the concept of summarizing in simple terms.",
"role": "user"
},
{
"content": "Summarizing is like taking a long story or article and squeezing it down to just the most important parts. It's like making a short summary of what happened, leaving out the details that aren't essential to understand the main idea.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Tell me about crizotinib.
Abstract
Anaplastic lymphoma kinase (ALK) gene rearrangements are present in a small subset of non-small-cell lung cancers. ALK-positivity confers sensitivity to small-molecule ALK kinase inhibitors, such as crizotinib. The integration of crizotinib into standard treatment practice in NSCLC will rest on the widespread implementation of an effective screening system for newly diagnosed patients with NSCLC which is flexible enough to incorporate new targets as treatments are developed for them. Phase I and II studies of crizotinib in ALK-positive lung cancer have demonstrated significant activity and impressive clinical benefit, which led to its early approval by USFDA in 2011. Although crizotinib induces remissions and extends the lives of patients, there have been reports of emerging resistance to Crizotinib therapy. In this review, we discuss the history, mechanism of action, uses, adverse effects, dose modifications and future challenges and opportunities for patients with ALK-positive lung cancers.
Keywords: ALK mutation, ALK inhibitors, ALK positive Non-small cell lung cancer, Crizotinib
Overview of Clinical Trials
The antitumor efficacy of crizotinib was initially demonstrated in two multicenter, single-arm studies.[23,24] Dosage for these extended series was 250 mg, orally, given twice a day, based on results from the initial phase I dose escalation study. In aggregate, these studies included 255 patients, all of whose tumors contained an ALK gene rearrangement, as shown by FISH. Overall, 95% of the patients had metastatic disease and 5% had locally advanced NSCLC. Overall, 94% of the patients had received prior systemic therapy for advanced or metastatic disease, and 76% had received two or more treatment regimens. The combined objective (complete plus partial) response rate was 55%, the majority of which was achieved during the first eight weeks of treatment. The median durations of response at the time of analysis of the two studies were 42 and 48 weeks, respectively [Table 1].
Table 1
Comparison of results of profile 1001 and profile 1005 trials
An external file that holds a picture, illustration, etc.
Object name is SAJC-2-91-g003.jpg
Evidence of the impact of crizotinib on the survival of patients came from a non-randomized, retrospective analysis of the patients enrolled in the phase I study.[25] The one- and two-year survival rates for patients treated with crizotinib were 74 and 54%, respectively, with a median follow-up of 18 months. In a cohort of 36 patients with the ALK fusion oncogene, who were not treated with crizotinib, the survival rates at one- and two-years were 44 and 12%, respectively. A comparison with a larger cohort of patients with wild-type tumors did not identify a difference when compared with those with the ALK rearrangement not treated with crizotinib, suggesting that the presence of ALK rearrangement was not prognostically significant.
Conclusions
The presence of an ALK fusion oncogene defines a molecular subset of NSCLC with distinct clinical and pathological features. The patients most likely to harbor ALK rearrangement are relatively young, never or light smokers with adenocarcinoma. Whenever possible, therapy of patients with advanced NSCLC should be individualized, based on the molecular and histological features of the tumor. If feasible, patients should have the tumor tissue assessed for the presence of a somatic mutation in the EGFR, which confers sensitivity to the EGFR tyrosine kinase inhibitors and to the ALK fusion oncogene, which is associated with sensitivity to crizotinib.
Thus, crizotinib is an important unmet medical need. It is a straightforward, biology-based biomarker, predicting a high response rate in heavily pre-treated patients and is relatively non-toxic. It is a triumph for a targeted therapy in the era of oncogenic driver mutations.
Response: Crizotinib is a small-molecule anaplastic lymphoma kinase (ALK) inhibitor that can be used to induce remission in non-small-cell lung cancers or NSCLC when ALK mutations are present.
In a non-randomized, retrospective analysis from a phase 1 study, crizotinib was found to improve one to two-year survival rates for patients from 44-12% to 74-54%.
Crizotinib has been shown to be a relatively non-toxic biomarker that has accomplished successful targeted therapy for people with a somatic mutation of the EGFR who have sensitivity to the ALK fusion oncogene although it remains an unmet medical need.
There have been reports of increased resistance to crizotinib which may require further research.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "What are the different types of summaries, and what are their key features?",
"role": "user"
},
{
"content": "There are two main types of summaries: descriptive and informative. Descriptive summaries give a general overview of the main points without going into detail. Informative summaries provide a more detailed account of the key information and evidence, aiming to capture the essence of the original text.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Tell me about crizotinib.
Abstract
Anaplastic lymphoma kinase (ALK) gene rearrangements are present in a small subset of non-small-cell lung cancers. ALK-positivity confers sensitivity to small-molecule ALK kinase inhibitors, such as crizotinib. The integration of crizotinib into standard treatment practice in NSCLC will rest on the widespread implementation of an effective screening system for newly diagnosed patients with NSCLC which is flexible enough to incorporate new targets as treatments are developed for them. Phase I and II studies of crizotinib in ALK-positive lung cancer have demonstrated significant activity and impressive clinical benefit, which led to its early approval by USFDA in 2011. Although crizotinib induces remissions and extends the lives of patients, there have been reports of emerging resistance to Crizotinib therapy. In this review, we discuss the history, mechanism of action, uses, adverse effects, dose modifications and future challenges and opportunities for patients with ALK-positive lung cancers.
Keywords: ALK mutation, ALK inhibitors, ALK positive Non-small cell lung cancer, Crizotinib
Overview of Clinical Trials
The antitumor efficacy of crizotinib was initially demonstrated in two multicenter, single-arm studies.[23,24] Dosage for these extended series was 250 mg, orally, given twice a day, based on results from the initial phase I dose escalation study. In aggregate, these studies included 255 patients, all of whose tumors contained an ALK gene rearrangement, as shown by FISH. Overall, 95% of the patients had metastatic disease and 5% had locally advanced NSCLC. Overall, 94% of the patients had received prior systemic therapy for advanced or metastatic disease, and 76% had received two or more treatment regimens. The combined objective (complete plus partial) response rate was 55%, the majority of which was achieved during the first eight weeks of treatment. The median durations of response at the time of analysis of the two studies were 42 and 48 weeks, respectively [Table 1].
Table 1
Comparison of results of profile 1001 and profile 1005 trials
An external file that holds a picture, illustration, etc.
Object name is SAJC-2-91-g003.jpg
Evidence of the impact of crizotinib on the survival of patients came from a non-randomized, retrospective analysis of the patients enrolled in the phase I study.[25] The one- and two-year survival rates for patients treated with crizotinib were 74 and 54%, respectively, with a median follow-up of 18 months. In a cohort of 36 patients with the ALK fusion oncogene, who were not treated with crizotinib, the survival rates at one- and two-years were 44 and 12%, respectively. A comparison with a larger cohort of patients with wild-type tumors did not identify a difference when compared with those with the ALK rearrangement not treated with crizotinib, suggesting that the presence of ALK rearrangement was not prognostically significant.
Conclusions
The presence of an ALK fusion oncogene defines a molecular subset of NSCLC with distinct clinical and pathological features. The patients most likely to harbor ALK rearrangement are relatively young, never or light smokers with adenocarcinoma. Whenever possible, therapy of patients with advanced NSCLC should be individualized, based on the molecular and histological features of the tumor. If feasible, patients should have the tumor tissue assessed for the presence of a somatic mutation in the EGFR, which confers sensitivity to the EGFR tyrosine kinase inhibitors and to the ALK fusion oncogene, which is associated with sensitivity to crizotinib.
Thus, crizotinib is an important unmet medical need. It is a straightforward, biology-based biomarker, predicting a high response rate in heavily pre-treated patients and is relatively non-toxic. It is a triumph for a targeted therapy in the era of oncogenic driver mutations.
Response: Crizotinib is a small-molecule anaplastic lymphoma kinase (ALK) inhibitor that can be used to induce remission in non-small-cell lung cancers or NSCLC when ALK mutations are present.
In a non-randomized, retrospective analysis from a phase 1 study, crizotinib was found to improve one to two-year survival rates for patients from 44-12% to 74-54%.
Crizotinib has been shown to be a relatively non-toxic biomarker that has accomplished successful targeted therapy for people with a somatic mutation of the EGFR who have sensitivity to the ALK fusion oncogene although it remains an unmet medical need.
There have been reports of increased resistance to crizotinib which may require further research.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "How can I write a good summary?",
"role": "user"
},
{
"content": "To write a good summary, you need to read the original text carefully and identify the main points. Then, you can write a concise and clear overview that includes the key information, using your own words. Avoid adding your own opinions or interpretations, and keep it focused on the main message.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Tell me about crizotinib.
Abstract
Anaplastic lymphoma kinase (ALK) gene rearrangements are present in a small subset of non-small-cell lung cancers. ALK-positivity confers sensitivity to small-molecule ALK kinase inhibitors, such as crizotinib. The integration of crizotinib into standard treatment practice in NSCLC will rest on the widespread implementation of an effective screening system for newly diagnosed patients with NSCLC which is flexible enough to incorporate new targets as treatments are developed for them. Phase I and II studies of crizotinib in ALK-positive lung cancer have demonstrated significant activity and impressive clinical benefit, which led to its early approval by USFDA in 2011. Although crizotinib induces remissions and extends the lives of patients, there have been reports of emerging resistance to Crizotinib therapy. In this review, we discuss the history, mechanism of action, uses, adverse effects, dose modifications and future challenges and opportunities for patients with ALK-positive lung cancers.
Keywords: ALK mutation, ALK inhibitors, ALK positive Non-small cell lung cancer, Crizotinib
Overview of Clinical Trials
The antitumor efficacy of crizotinib was initially demonstrated in two multicenter, single-arm studies.[23,24] Dosage for these extended series was 250 mg, orally, given twice a day, based on results from the initial phase I dose escalation study. In aggregate, these studies included 255 patients, all of whose tumors contained an ALK gene rearrangement, as shown by FISH. Overall, 95% of the patients had metastatic disease and 5% had locally advanced NSCLC. Overall, 94% of the patients had received prior systemic therapy for advanced or metastatic disease, and 76% had received two or more treatment regimens. The combined objective (complete plus partial) response rate was 55%, the majority of which was achieved during the first eight weeks of treatment. The median durations of response at the time of analysis of the two studies were 42 and 48 weeks, respectively [Table 1].
Table 1
Comparison of results of profile 1001 and profile 1005 trials
An external file that holds a picture, illustration, etc.
Object name is SAJC-2-91-g003.jpg
Evidence of the impact of crizotinib on the survival of patients came from a non-randomized, retrospective analysis of the patients enrolled in the phase I study.[25] The one- and two-year survival rates for patients treated with crizotinib were 74 and 54%, respectively, with a median follow-up of 18 months. In a cohort of 36 patients with the ALK fusion oncogene, who were not treated with crizotinib, the survival rates at one- and two-years were 44 and 12%, respectively. A comparison with a larger cohort of patients with wild-type tumors did not identify a difference when compared with those with the ALK rearrangement not treated with crizotinib, suggesting that the presence of ALK rearrangement was not prognostically significant.
Conclusions
The presence of an ALK fusion oncogene defines a molecular subset of NSCLC with distinct clinical and pathological features. The patients most likely to harbor ALK rearrangement are relatively young, never or light smokers with adenocarcinoma. Whenever possible, therapy of patients with advanced NSCLC should be individualized, based on the molecular and histological features of the tumor. If feasible, patients should have the tumor tissue assessed for the presence of a somatic mutation in the EGFR, which confers sensitivity to the EGFR tyrosine kinase inhibitors and to the ALK fusion oncogene, which is associated with sensitivity to crizotinib.
Thus, crizotinib is an important unmet medical need. It is a straightforward, biology-based biomarker, predicting a high response rate in heavily pre-treated patients and is relatively non-toxic. It is a triumph for a targeted therapy in the era of oncogenic driver mutations.
Response: Crizotinib is a small-molecule anaplastic lymphoma kinase (ALK) inhibitor that can be used to induce remission in non-small-cell lung cancers or NSCLC when ALK mutations are present.
In a non-randomized, retrospective analysis from a phase 1 study, crizotinib was found to improve one to two-year survival rates for patients from 44-12% to 74-54%.
Crizotinib has been shown to be a relatively non-toxic biomarker that has accomplished successful targeted therapy for people with a somatic mutation of the EGFR who have sensitivity to the ALK fusion oncogene although it remains an unmet medical need.
There have been reports of increased resistance to crizotinib which may require further research.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "What are some common mistakes people make when summarizing?",
"role": "user"
},
{
"content": "Common mistakes when summarizing include leaving out important information, including too many details, adding your own opinions, and not using your own words. It's also important to avoid plagiarism and ensure you cite your sources properly.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Tell me about crizotinib.
Abstract
Anaplastic lymphoma kinase (ALK) gene rearrangements are present in a small subset of non-small-cell lung cancers. ALK-positivity confers sensitivity to small-molecule ALK kinase inhibitors, such as crizotinib. The integration of crizotinib into standard treatment practice in NSCLC will rest on the widespread implementation of an effective screening system for newly diagnosed patients with NSCLC which is flexible enough to incorporate new targets as treatments are developed for them. Phase I and II studies of crizotinib in ALK-positive lung cancer have demonstrated significant activity and impressive clinical benefit, which led to its early approval by USFDA in 2011. Although crizotinib induces remissions and extends the lives of patients, there have been reports of emerging resistance to Crizotinib therapy. In this review, we discuss the history, mechanism of action, uses, adverse effects, dose modifications and future challenges and opportunities for patients with ALK-positive lung cancers.
Keywords: ALK mutation, ALK inhibitors, ALK positive Non-small cell lung cancer, Crizotinib
Overview of Clinical Trials
The antitumor efficacy of crizotinib was initially demonstrated in two multicenter, single-arm studies.[23,24] Dosage for these extended series was 250 mg, orally, given twice a day, based on results from the initial phase I dose escalation study. In aggregate, these studies included 255 patients, all of whose tumors contained an ALK gene rearrangement, as shown by FISH. Overall, 95% of the patients had metastatic disease and 5% had locally advanced NSCLC. Overall, 94% of the patients had received prior systemic therapy for advanced or metastatic disease, and 76% had received two or more treatment regimens. The combined objective (complete plus partial) response rate was 55%, the majority of which was achieved during the first eight weeks of treatment. The median durations of response at the time of analysis of the two studies were 42 and 48 weeks, respectively [Table 1].
Table 1
Comparison of results of profile 1001 and profile 1005 trials
An external file that holds a picture, illustration, etc.
Object name is SAJC-2-91-g003.jpg
Evidence of the impact of crizotinib on the survival of patients came from a non-randomized, retrospective analysis of the patients enrolled in the phase I study.[25] The one- and two-year survival rates for patients treated with crizotinib were 74 and 54%, respectively, with a median follow-up of 18 months. In a cohort of 36 patients with the ALK fusion oncogene, who were not treated with crizotinib, the survival rates at one- and two-years were 44 and 12%, respectively. A comparison with a larger cohort of patients with wild-type tumors did not identify a difference when compared with those with the ALK rearrangement not treated with crizotinib, suggesting that the presence of ALK rearrangement was not prognostically significant.
Conclusions
The presence of an ALK fusion oncogene defines a molecular subset of NSCLC with distinct clinical and pathological features. The patients most likely to harbor ALK rearrangement are relatively young, never or light smokers with adenocarcinoma. Whenever possible, therapy of patients with advanced NSCLC should be individualized, based on the molecular and histological features of the tumor. If feasible, patients should have the tumor tissue assessed for the presence of a somatic mutation in the EGFR, which confers sensitivity to the EGFR tyrosine kinase inhibitors and to the ALK fusion oncogene, which is associated with sensitivity to crizotinib.
Thus, crizotinib is an important unmet medical need. It is a straightforward, biology-based biomarker, predicting a high response rate in heavily pre-treated patients and is relatively non-toxic. It is a triumph for a targeted therapy in the era of oncogenic driver mutations.
Response: Crizotinib is a small-molecule anaplastic lymphoma kinase (ALK) inhibitor that can be used to induce remission in non-small-cell lung cancers or NSCLC when ALK mutations are present.
In a non-randomized, retrospective analysis from a phase 1 study, crizotinib was found to improve one to two-year survival rates for patients from 44-12% to 74-54%.
Crizotinib has been shown to be a relatively non-toxic biomarker that has accomplished successful targeted therapy for people with a somatic mutation of the EGFR who have sensitivity to the ALK fusion oncogene although it remains an unmet medical need.
There have been reports of increased resistance to crizotinib which may require further research.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Why is summarizing an important skill?",
"role": "user"
},
{
"content": "Summarizing is a valuable skill because it helps you understand and remember information better. It's also useful for saving time, sharing information efficiently, and demonstrating your understanding of a topic. It's a fundamental skill in many academic, professional, and personal situations.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Tell me about crizotinib.
Abstract
Anaplastic lymphoma kinase (ALK) gene rearrangements are present in a small subset of non-small-cell lung cancers. ALK-positivity confers sensitivity to small-molecule ALK kinase inhibitors, such as crizotinib. The integration of crizotinib into standard treatment practice in NSCLC will rest on the widespread implementation of an effective screening system for newly diagnosed patients with NSCLC which is flexible enough to incorporate new targets as treatments are developed for them. Phase I and II studies of crizotinib in ALK-positive lung cancer have demonstrated significant activity and impressive clinical benefit, which led to its early approval by USFDA in 2011. Although crizotinib induces remissions and extends the lives of patients, there have been reports of emerging resistance to Crizotinib therapy. In this review, we discuss the history, mechanism of action, uses, adverse effects, dose modifications and future challenges and opportunities for patients with ALK-positive lung cancers.
Keywords: ALK mutation, ALK inhibitors, ALK positive Non-small cell lung cancer, Crizotinib
Overview of Clinical Trials
The antitumor efficacy of crizotinib was initially demonstrated in two multicenter, single-arm studies.[23,24] Dosage for these extended series was 250 mg, orally, given twice a day, based on results from the initial phase I dose escalation study. In aggregate, these studies included 255 patients, all of whose tumors contained an ALK gene rearrangement, as shown by FISH. Overall, 95% of the patients had metastatic disease and 5% had locally advanced NSCLC. Overall, 94% of the patients had received prior systemic therapy for advanced or metastatic disease, and 76% had received two or more treatment regimens. The combined objective (complete plus partial) response rate was 55%, the majority of which was achieved during the first eight weeks of treatment. The median durations of response at the time of analysis of the two studies were 42 and 48 weeks, respectively [Table 1].
Table 1
Comparison of results of profile 1001 and profile 1005 trials
An external file that holds a picture, illustration, etc.
Object name is SAJC-2-91-g003.jpg
Evidence of the impact of crizotinib on the survival of patients came from a non-randomized, retrospective analysis of the patients enrolled in the phase I study.[25] The one- and two-year survival rates for patients treated with crizotinib were 74 and 54%, respectively, with a median follow-up of 18 months. In a cohort of 36 patients with the ALK fusion oncogene, who were not treated with crizotinib, the survival rates at one- and two-years were 44 and 12%, respectively. A comparison with a larger cohort of patients with wild-type tumors did not identify a difference when compared with those with the ALK rearrangement not treated with crizotinib, suggesting that the presence of ALK rearrangement was not prognostically significant.
Conclusions
The presence of an ALK fusion oncogene defines a molecular subset of NSCLC with distinct clinical and pathological features. The patients most likely to harbor ALK rearrangement are relatively young, never or light smokers with adenocarcinoma. Whenever possible, therapy of patients with advanced NSCLC should be individualized, based on the molecular and histological features of the tumor. If feasible, patients should have the tumor tissue assessed for the presence of a somatic mutation in the EGFR, which confers sensitivity to the EGFR tyrosine kinase inhibitors and to the ALK fusion oncogene, which is associated with sensitivity to crizotinib.
Thus, crizotinib is an important unmet medical need. It is a straightforward, biology-based biomarker, predicting a high response rate in heavily pre-treated patients and is relatively non-toxic. It is a triumph for a targeted therapy in the era of oncogenic driver mutations.
Response: Crizotinib is a small-molecule anaplastic lymphoma kinase (ALK) inhibitor that can be used to induce remission in non-small-cell lung cancers or NSCLC when ALK mutations are present.
In a non-randomized, retrospective analysis from a phase 1 study, crizotinib was found to improve one to two-year survival rates for patients from 44-12% to 74-54%.
Crizotinib has been shown to be a relatively non-toxic biomarker that has accomplished successful targeted therapy for people with a somatic mutation of the EGFR who have sensitivity to the ALK fusion oncogene although it remains an unmet medical need.
There have been reports of increased resistance to crizotinib which may require further research.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "What are some strategies for summarizing effectively?",
"role": "user"
},
{
"content": "Some effective summarizing strategies include highlighting key points, taking notes in your own words, identifying the main idea, creating a mind map, and using summarizing tools like bullet points or outlines. It's also helpful to practice summarizing different types of texts and feedback on your work.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Tell me about crizotinib.
Abstract
Anaplastic lymphoma kinase (ALK) gene rearrangements are present in a small subset of non-small-cell lung cancers. ALK-positivity confers sensitivity to small-molecule ALK kinase inhibitors, such as crizotinib. The integration of crizotinib into standard treatment practice in NSCLC will rest on the widespread implementation of an effective screening system for newly diagnosed patients with NSCLC which is flexible enough to incorporate new targets as treatments are developed for them. Phase I and II studies of crizotinib in ALK-positive lung cancer have demonstrated significant activity and impressive clinical benefit, which led to its early approval by USFDA in 2011. Although crizotinib induces remissions and extends the lives of patients, there have been reports of emerging resistance to Crizotinib therapy. In this review, we discuss the history, mechanism of action, uses, adverse effects, dose modifications and future challenges and opportunities for patients with ALK-positive lung cancers.
Keywords: ALK mutation, ALK inhibitors, ALK positive Non-small cell lung cancer, Crizotinib
Overview of Clinical Trials
The antitumor efficacy of crizotinib was initially demonstrated in two multicenter, single-arm studies.[23,24] Dosage for these extended series was 250 mg, orally, given twice a day, based on results from the initial phase I dose escalation study. In aggregate, these studies included 255 patients, all of whose tumors contained an ALK gene rearrangement, as shown by FISH. Overall, 95% of the patients had metastatic disease and 5% had locally advanced NSCLC. Overall, 94% of the patients had received prior systemic therapy for advanced or metastatic disease, and 76% had received two or more treatment regimens. The combined objective (complete plus partial) response rate was 55%, the majority of which was achieved during the first eight weeks of treatment. The median durations of response at the time of analysis of the two studies were 42 and 48 weeks, respectively [Table 1].
Table 1
Comparison of results of profile 1001 and profile 1005 trials
An external file that holds a picture, illustration, etc.
Object name is SAJC-2-91-g003.jpg
Evidence of the impact of crizotinib on the survival of patients came from a non-randomized, retrospective analysis of the patients enrolled in the phase I study.[25] The one- and two-year survival rates for patients treated with crizotinib were 74 and 54%, respectively, with a median follow-up of 18 months. In a cohort of 36 patients with the ALK fusion oncogene, who were not treated with crizotinib, the survival rates at one- and two-years were 44 and 12%, respectively. A comparison with a larger cohort of patients with wild-type tumors did not identify a difference when compared with those with the ALK rearrangement not treated with crizotinib, suggesting that the presence of ALK rearrangement was not prognostically significant.
Conclusions
The presence of an ALK fusion oncogene defines a molecular subset of NSCLC with distinct clinical and pathological features. The patients most likely to harbor ALK rearrangement are relatively young, never or light smokers with adenocarcinoma. Whenever possible, therapy of patients with advanced NSCLC should be individualized, based on the molecular and histological features of the tumor. If feasible, patients should have the tumor tissue assessed for the presence of a somatic mutation in the EGFR, which confers sensitivity to the EGFR tyrosine kinase inhibitors and to the ALK fusion oncogene, which is associated with sensitivity to crizotinib.
Thus, crizotinib is an important unmet medical need. It is a straightforward, biology-based biomarker, predicting a high response rate in heavily pre-treated patients and is relatively non-toxic. It is a triumph for a targeted therapy in the era of oncogenic driver mutations.
Response: Crizotinib is a small-molecule anaplastic lymphoma kinase (ALK) inhibitor that can be used to induce remission in non-small-cell lung cancers or NSCLC when ALK mutations are present.
In a non-randomized, retrospective analysis from a phase 1 study, crizotinib was found to improve one to two-year survival rates for patients from 44-12% to 74-54%.
Crizotinib has been shown to be a relatively non-toxic biomarker that has accomplished successful targeted therapy for people with a somatic mutation of the EGFR who have sensitivity to the ALK fusion oncogene although it remains an unmet medical need.
There have been reports of increased resistance to crizotinib which may require further research.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "How does summarizing relate to critical thinking?",
"role": "user"
},
{
"content": "Summarizing is closely linked to critical thinking. It requires you to analyze the information, identify the most important parts, and synthesize it into a concise form. This process helps you develop your ability to evaluate information, identify biases, and form your own conclusions.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Tell me about crizotinib.
Abstract
Anaplastic lymphoma kinase (ALK) gene rearrangements are present in a small subset of non-small-cell lung cancers. ALK-positivity confers sensitivity to small-molecule ALK kinase inhibitors, such as crizotinib. The integration of crizotinib into standard treatment practice in NSCLC will rest on the widespread implementation of an effective screening system for newly diagnosed patients with NSCLC which is flexible enough to incorporate new targets as treatments are developed for them. Phase I and II studies of crizotinib in ALK-positive lung cancer have demonstrated significant activity and impressive clinical benefit, which led to its early approval by USFDA in 2011. Although crizotinib induces remissions and extends the lives of patients, there have been reports of emerging resistance to Crizotinib therapy. In this review, we discuss the history, mechanism of action, uses, adverse effects, dose modifications and future challenges and opportunities for patients with ALK-positive lung cancers.
Keywords: ALK mutation, ALK inhibitors, ALK positive Non-small cell lung cancer, Crizotinib
Overview of Clinical Trials
The antitumor efficacy of crizotinib was initially demonstrated in two multicenter, single-arm studies.[23,24] Dosage for these extended series was 250 mg, orally, given twice a day, based on results from the initial phase I dose escalation study. In aggregate, these studies included 255 patients, all of whose tumors contained an ALK gene rearrangement, as shown by FISH. Overall, 95% of the patients had metastatic disease and 5% had locally advanced NSCLC. Overall, 94% of the patients had received prior systemic therapy for advanced or metastatic disease, and 76% had received two or more treatment regimens. The combined objective (complete plus partial) response rate was 55%, the majority of which was achieved during the first eight weeks of treatment. The median durations of response at the time of analysis of the two studies were 42 and 48 weeks, respectively [Table 1].
Table 1
Comparison of results of profile 1001 and profile 1005 trials
An external file that holds a picture, illustration, etc.
Object name is SAJC-2-91-g003.jpg
Evidence of the impact of crizotinib on the survival of patients came from a non-randomized, retrospective analysis of the patients enrolled in the phase I study.[25] The one- and two-year survival rates for patients treated with crizotinib were 74 and 54%, respectively, with a median follow-up of 18 months. In a cohort of 36 patients with the ALK fusion oncogene, who were not treated with crizotinib, the survival rates at one- and two-years were 44 and 12%, respectively. A comparison with a larger cohort of patients with wild-type tumors did not identify a difference when compared with those with the ALK rearrangement not treated with crizotinib, suggesting that the presence of ALK rearrangement was not prognostically significant.
Conclusions
The presence of an ALK fusion oncogene defines a molecular subset of NSCLC with distinct clinical and pathological features. The patients most likely to harbor ALK rearrangement are relatively young, never or light smokers with adenocarcinoma. Whenever possible, therapy of patients with advanced NSCLC should be individualized, based on the molecular and histological features of the tumor. If feasible, patients should have the tumor tissue assessed for the presence of a somatic mutation in the EGFR, which confers sensitivity to the EGFR tyrosine kinase inhibitors and to the ALK fusion oncogene, which is associated with sensitivity to crizotinib.
Thus, crizotinib is an important unmet medical need. It is a straightforward, biology-based biomarker, predicting a high response rate in heavily pre-treated patients and is relatively non-toxic. It is a triumph for a targeted therapy in the era of oncogenic driver mutations.
Response: Crizotinib is a small-molecule anaplastic lymphoma kinase (ALK) inhibitor that can be used to induce remission in non-small-cell lung cancers or NSCLC when ALK mutations are present.
In a non-randomized, retrospective analysis from a phase 1 study, crizotinib was found to improve one to two-year survival rates for patients from 44-12% to 74-54%.
Crizotinib has been shown to be a relatively non-toxic biomarker that has accomplished successful targeted therapy for people with a somatic mutation of the EGFR who have sensitivity to the ALK fusion oncogene although it remains an unmet medical need.
There have been reports of increased resistance to crizotinib which may require further research.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Can you give me an example of how to summarize a scientific article?",
"role": "user"
},
{
"content": "To summarize a scientific article, first identify the research question, hypothesis, methods, results, and conclusions. Then, write a concise overview of these key elements, highlighting the main findings and their implications. Remember to cite the source and avoid technical jargon that might not be understood by a general audience.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Tell me about crizotinib.
Abstract
Anaplastic lymphoma kinase (ALK) gene rearrangements are present in a small subset of non-small-cell lung cancers. ALK-positivity confers sensitivity to small-molecule ALK kinase inhibitors, such as crizotinib. The integration of crizotinib into standard treatment practice in NSCLC will rest on the widespread implementation of an effective screening system for newly diagnosed patients with NSCLC which is flexible enough to incorporate new targets as treatments are developed for them. Phase I and II studies of crizotinib in ALK-positive lung cancer have demonstrated significant activity and impressive clinical benefit, which led to its early approval by USFDA in 2011. Although crizotinib induces remissions and extends the lives of patients, there have been reports of emerging resistance to Crizotinib therapy. In this review, we discuss the history, mechanism of action, uses, adverse effects, dose modifications and future challenges and opportunities for patients with ALK-positive lung cancers.
Keywords: ALK mutation, ALK inhibitors, ALK positive Non-small cell lung cancer, Crizotinib
Overview of Clinical Trials
The antitumor efficacy of crizotinib was initially demonstrated in two multicenter, single-arm studies.[23,24] Dosage for these extended series was 250 mg, orally, given twice a day, based on results from the initial phase I dose escalation study. In aggregate, these studies included 255 patients, all of whose tumors contained an ALK gene rearrangement, as shown by FISH. Overall, 95% of the patients had metastatic disease and 5% had locally advanced NSCLC. Overall, 94% of the patients had received prior systemic therapy for advanced or metastatic disease, and 76% had received two or more treatment regimens. The combined objective (complete plus partial) response rate was 55%, the majority of which was achieved during the first eight weeks of treatment. The median durations of response at the time of analysis of the two studies were 42 and 48 weeks, respectively [Table 1].
Table 1
Comparison of results of profile 1001 and profile 1005 trials
An external file that holds a picture, illustration, etc.
Object name is SAJC-2-91-g003.jpg
Evidence of the impact of crizotinib on the survival of patients came from a non-randomized, retrospective analysis of the patients enrolled in the phase I study.[25] The one- and two-year survival rates for patients treated with crizotinib were 74 and 54%, respectively, with a median follow-up of 18 months. In a cohort of 36 patients with the ALK fusion oncogene, who were not treated with crizotinib, the survival rates at one- and two-years were 44 and 12%, respectively. A comparison with a larger cohort of patients with wild-type tumors did not identify a difference when compared with those with the ALK rearrangement not treated with crizotinib, suggesting that the presence of ALK rearrangement was not prognostically significant.
Conclusions
The presence of an ALK fusion oncogene defines a molecular subset of NSCLC with distinct clinical and pathological features. The patients most likely to harbor ALK rearrangement are relatively young, never or light smokers with adenocarcinoma. Whenever possible, therapy of patients with advanced NSCLC should be individualized, based on the molecular and histological features of the tumor. If feasible, patients should have the tumor tissue assessed for the presence of a somatic mutation in the EGFR, which confers sensitivity to the EGFR tyrosine kinase inhibitors and to the ALK fusion oncogene, which is associated with sensitivity to crizotinib.
Thus, crizotinib is an important unmet medical need. It is a straightforward, biology-based biomarker, predicting a high response rate in heavily pre-treated patients and is relatively non-toxic. It is a triumph for a targeted therapy in the era of oncogenic driver mutations.
Response: Crizotinib is a small-molecule anaplastic lymphoma kinase (ALK) inhibitor that can be used to induce remission in non-small-cell lung cancers or NSCLC when ALK mutations are present.
In a non-randomized, retrospective analysis from a phase 1 study, crizotinib was found to improve one to two-year survival rates for patients from 44-12% to 74-54%.
Crizotinib has been shown to be a relatively non-toxic biomarker that has accomplished successful targeted therapy for people with a somatic mutation of the EGFR who have sensitivity to the ALK fusion oncogene although it remains an unmet medical need.
There have been reports of increased resistance to crizotinib which may require further research.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "What are some ways summarizing can be used in everyday life?",
"role": "user"
},
{
"content": "Summarizing is used in everyday life in countless ways. For example, you might summarize a conversation with a friend, write a brief email summarizing a meeting, or create a summary of a book you've read. It's a versatile skill that can help you communicate effectively in various situations.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Tell me about crizotinib.
Abstract
Anaplastic lymphoma kinase (ALK) gene rearrangements are present in a small subset of non-small-cell lung cancers. ALK-positivity confers sensitivity to small-molecule ALK kinase inhibitors, such as crizotinib. The integration of crizotinib into standard treatment practice in NSCLC will rest on the widespread implementation of an effective screening system for newly diagnosed patients with NSCLC which is flexible enough to incorporate new targets as treatments are developed for them. Phase I and II studies of crizotinib in ALK-positive lung cancer have demonstrated significant activity and impressive clinical benefit, which led to its early approval by USFDA in 2011. Although crizotinib induces remissions and extends the lives of patients, there have been reports of emerging resistance to Crizotinib therapy. In this review, we discuss the history, mechanism of action, uses, adverse effects, dose modifications and future challenges and opportunities for patients with ALK-positive lung cancers.
Keywords: ALK mutation, ALK inhibitors, ALK positive Non-small cell lung cancer, Crizotinib
Overview of Clinical Trials
The antitumor efficacy of crizotinib was initially demonstrated in two multicenter, single-arm studies.[23,24] Dosage for these extended series was 250 mg, orally, given twice a day, based on results from the initial phase I dose escalation study. In aggregate, these studies included 255 patients, all of whose tumors contained an ALK gene rearrangement, as shown by FISH. Overall, 95% of the patients had metastatic disease and 5% had locally advanced NSCLC. Overall, 94% of the patients had received prior systemic therapy for advanced or metastatic disease, and 76% had received two or more treatment regimens. The combined objective (complete plus partial) response rate was 55%, the majority of which was achieved during the first eight weeks of treatment. The median durations of response at the time of analysis of the two studies were 42 and 48 weeks, respectively [Table 1].
Table 1
Comparison of results of profile 1001 and profile 1005 trials
An external file that holds a picture, illustration, etc.
Object name is SAJC-2-91-g003.jpg
Evidence of the impact of crizotinib on the survival of patients came from a non-randomized, retrospective analysis of the patients enrolled in the phase I study.[25] The one- and two-year survival rates for patients treated with crizotinib were 74 and 54%, respectively, with a median follow-up of 18 months. In a cohort of 36 patients with the ALK fusion oncogene, who were not treated with crizotinib, the survival rates at one- and two-years were 44 and 12%, respectively. A comparison with a larger cohort of patients with wild-type tumors did not identify a difference when compared with those with the ALK rearrangement not treated with crizotinib, suggesting that the presence of ALK rearrangement was not prognostically significant.
Conclusions
The presence of an ALK fusion oncogene defines a molecular subset of NSCLC with distinct clinical and pathological features. The patients most likely to harbor ALK rearrangement are relatively young, never or light smokers with adenocarcinoma. Whenever possible, therapy of patients with advanced NSCLC should be individualized, based on the molecular and histological features of the tumor. If feasible, patients should have the tumor tissue assessed for the presence of a somatic mutation in the EGFR, which confers sensitivity to the EGFR tyrosine kinase inhibitors and to the ALK fusion oncogene, which is associated with sensitivity to crizotinib.
Thus, crizotinib is an important unmet medical need. It is a straightforward, biology-based biomarker, predicting a high response rate in heavily pre-treated patients and is relatively non-toxic. It is a triumph for a targeted therapy in the era of oncogenic driver mutations.
Response: Crizotinib is a small-molecule anaplastic lymphoma kinase (ALK) inhibitor that can be used to induce remission in non-small-cell lung cancers or NSCLC when ALK mutations are present.
In a non-randomized, retrospective analysis from a phase 1 study, crizotinib was found to improve one to two-year survival rates for patients from 44-12% to 74-54%.
Crizotinib has been shown to be a relatively non-toxic biomarker that has accomplished successful targeted therapy for people with a somatic mutation of the EGFR who have sensitivity to the ALK fusion oncogene although it remains an unmet medical need.
There have been reports of increased resistance to crizotinib which may require further research.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "How can I improve my summarizing skills?",
"role": "user"
},
{
"content": "To improve your summarizing skills, practice regularly, seek feedback from others, read different types of texts, and experiment with different summarizing techniques. You can also explore resources like online guides, tutorials, and workshops to enhance your understanding and refine your skills.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: It takes decades for sea turtles to reach sexual maturity. Maturity may range from as early as 7 to 13 years for leatherbacks, 11 to 16 years for both species of ridleys, 20 to 25 years in hawksbills, 25 to 35 years for loggerheads, and 26 to 40 years in green sea turtles. Mature sea turtles may migrate thousands of miles to reach breeding sites. After mating at sea, adult female sea turtles return to land to lay their eggs. Different species of sea turtles exhibit various levels of philopatry. In the extreme case, females return to the same beach where they hatched. This can take place every two to four years in maturity. The mature nesting female hauls herself onto the beach, nearly always at night, and finds suitable sand in which to create a nest. Using her hind flippers, she digs a circular hole 40 to 50 centimeters (16 to 20 in) deep. After the hole is dug, the female then starts filling the nest with her clutch of soft-shelled eggs. Depending on the species, a typical clutch may contain 50–350 eggs. After laying, she re-fills the nest with sand, re-sculpting and smoothing the surface, and then camouflaging the nest with vegetation until it is relatively undetectable visually. She may also dig decoy nests. The whole process takes 30 to 60 minutes. She then returns to the ocean, leaving the eggs untended.
What does the passage say about sea turtles?
Response: This passage talks about the reproduction process of sea turtles specifically mentioning:
• It can take up to four decades for a sea turtle to reach sexual maturity depending on the breed
• Sea turtles of breeding age can travel thousands of miles before they settle upon a location to lay their eggs, some may return to where they were hatched
• Mature females can lay eggs every two to four years
• The egg-laying and the disguising process takes the female about an hour to complete:
• The female digs a deep round hole to lay her eggs in (50 – 350 eggs)
• She then covers the eggs with sand and disguises the spot to prevent scavaging
• Oftentimes she creates fake beds to confuse predators
• Once the eggs have been laid and properly concealed the female returns to the ocean and the eggs are left to their own devices
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "The Earth's atmosphere is composed of several layers, each with unique characteristics. The troposphere, the lowest layer, is where we live and experience weather. Above it lies the stratosphere, home to the ozone layer that shields us from harmful ultraviolet radiation. The mesosphere is the next layer, where most meteors burn up. The thermosphere, known for its high temperatures, is where the International Space Station orbits. Finally, the exosphere is the outermost layer, gradually fading into outer space. Each layer plays a crucial role in maintaining Earth's environment and protecting life.",
"role": "user"
},
{
"content": "This passage explains the structure of Earth's atmosphere, outlining the five main layers: the troposphere, stratosphere, mesosphere, thermosphere, and exosphere. It highlights the key characteristics and functions of each layer, including the troposphere's role in weather, the stratosphere's ozone layer, the mesosphere's meteor burning, the thermosphere's high temperatures and the International Space Station's orbit, and the exosphere's gradual transition to outer space.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: It takes decades for sea turtles to reach sexual maturity. Maturity may range from as early as 7 to 13 years for leatherbacks, 11 to 16 years for both species of ridleys, 20 to 25 years in hawksbills, 25 to 35 years for loggerheads, and 26 to 40 years in green sea turtles. Mature sea turtles may migrate thousands of miles to reach breeding sites. After mating at sea, adult female sea turtles return to land to lay their eggs. Different species of sea turtles exhibit various levels of philopatry. In the extreme case, females return to the same beach where they hatched. This can take place every two to four years in maturity. The mature nesting female hauls herself onto the beach, nearly always at night, and finds suitable sand in which to create a nest. Using her hind flippers, she digs a circular hole 40 to 50 centimeters (16 to 20 in) deep. After the hole is dug, the female then starts filling the nest with her clutch of soft-shelled eggs. Depending on the species, a typical clutch may contain 50–350 eggs. After laying, she re-fills the nest with sand, re-sculpting and smoothing the surface, and then camouflaging the nest with vegetation until it is relatively undetectable visually. She may also dig decoy nests. The whole process takes 30 to 60 minutes. She then returns to the ocean, leaving the eggs untended.
What does the passage say about sea turtles?
Response: This passage talks about the reproduction process of sea turtles specifically mentioning:
• It can take up to four decades for a sea turtle to reach sexual maturity depending on the breed
• Sea turtles of breeding age can travel thousands of miles before they settle upon a location to lay their eggs, some may return to where they were hatched
• Mature females can lay eggs every two to four years
• The egg-laying and the disguising process takes the female about an hour to complete:
• The female digs a deep round hole to lay her eggs in (50 – 350 eggs)
• She then covers the eggs with sand and disguises the spot to prevent scavaging
• Oftentimes she creates fake beds to confuse predators
• Once the eggs have been laid and properly concealed the female returns to the ocean and the eggs are left to their own devices
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "The human heart is a vital organ responsible for pumping blood throughout the body. It is a four-chambered pump with two atria and two ventricles. The right atrium receives deoxygenated blood from the body and pumps it to the right ventricle, which then sends it to the lungs for oxygenation. The oxygenated blood returns to the heart through the left atrium and is pumped to the left ventricle, which then sends it out to the body. This continuous cycle ensures the delivery of oxygen and nutrients to all cells and the removal of waste products.",
"role": "user"
},
{
"content": "This passage describes the structure and function of the human heart. It explains that the heart is a four-chambered pump with two atria and two ventricles that work together to circulate blood throughout the body. It outlines the process of deoxygenated blood entering the right atrium, being pumped to the right ventricle, then to the lungs for oxygenation, returning to the left atrium, being pumped to the left ventricle, and finally being sent out to the body. This continuous cycle ensures proper blood flow and oxygen delivery to all cells.",
"role": "assistant"
}
] |
Summarization
|
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Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: It takes decades for sea turtles to reach sexual maturity. Maturity may range from as early as 7 to 13 years for leatherbacks, 11 to 16 years for both species of ridleys, 20 to 25 years in hawksbills, 25 to 35 years for loggerheads, and 26 to 40 years in green sea turtles. Mature sea turtles may migrate thousands of miles to reach breeding sites. After mating at sea, adult female sea turtles return to land to lay their eggs. Different species of sea turtles exhibit various levels of philopatry. In the extreme case, females return to the same beach where they hatched. This can take place every two to four years in maturity. The mature nesting female hauls herself onto the beach, nearly always at night, and finds suitable sand in which to create a nest. Using her hind flippers, she digs a circular hole 40 to 50 centimeters (16 to 20 in) deep. After the hole is dug, the female then starts filling the nest with her clutch of soft-shelled eggs. Depending on the species, a typical clutch may contain 50–350 eggs. After laying, she re-fills the nest with sand, re-sculpting and smoothing the surface, and then camouflaging the nest with vegetation until it is relatively undetectable visually. She may also dig decoy nests. The whole process takes 30 to 60 minutes. She then returns to the ocean, leaving the eggs untended.
What does the passage say about sea turtles?
Response: This passage talks about the reproduction process of sea turtles specifically mentioning:
• It can take up to four decades for a sea turtle to reach sexual maturity depending on the breed
• Sea turtles of breeding age can travel thousands of miles before they settle upon a location to lay their eggs, some may return to where they were hatched
• Mature females can lay eggs every two to four years
• The egg-laying and the disguising process takes the female about an hour to complete:
• The female digs a deep round hole to lay her eggs in (50 – 350 eggs)
• She then covers the eggs with sand and disguises the spot to prevent scavaging
• Oftentimes she creates fake beds to confuse predators
• Once the eggs have been laid and properly concealed the female returns to the ocean and the eggs are left to their own devices
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Photosynthesis is the process by which plants, algae, and some bacteria convert light energy into chemical energy. It occurs in chloroplasts, where chlorophyll pigments absorb light energy. During photosynthesis, carbon dioxide from the atmosphere and water from the soil are combined to produce glucose (a sugar) and oxygen. Glucose serves as food for the plant, while oxygen is released as a byproduct. This process is essential for life on Earth, providing both food and oxygen for living organisms.",
"role": "user"
},
{
"content": "This passage explains photosynthesis, the process by which plants, algae, and certain bacteria use light energy to create chemical energy. It describes the role of chloroplasts and chlorophyll pigments in absorbing light energy. It outlines the process of combining carbon dioxide and water to produce glucose (a sugar) and oxygen. It highlights the importance of photosynthesis for life on Earth, as it provides both food and oxygen.",
"role": "assistant"
}
] |
Summarization
|
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gemini-1.5-flash-preview-0514
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Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: It takes decades for sea turtles to reach sexual maturity. Maturity may range from as early as 7 to 13 years for leatherbacks, 11 to 16 years for both species of ridleys, 20 to 25 years in hawksbills, 25 to 35 years for loggerheads, and 26 to 40 years in green sea turtles. Mature sea turtles may migrate thousands of miles to reach breeding sites. After mating at sea, adult female sea turtles return to land to lay their eggs. Different species of sea turtles exhibit various levels of philopatry. In the extreme case, females return to the same beach where they hatched. This can take place every two to four years in maturity. The mature nesting female hauls herself onto the beach, nearly always at night, and finds suitable sand in which to create a nest. Using her hind flippers, she digs a circular hole 40 to 50 centimeters (16 to 20 in) deep. After the hole is dug, the female then starts filling the nest with her clutch of soft-shelled eggs. Depending on the species, a typical clutch may contain 50–350 eggs. After laying, she re-fills the nest with sand, re-sculpting and smoothing the surface, and then camouflaging the nest with vegetation until it is relatively undetectable visually. She may also dig decoy nests. The whole process takes 30 to 60 minutes. She then returns to the ocean, leaving the eggs untended.
What does the passage say about sea turtles?
Response: This passage talks about the reproduction process of sea turtles specifically mentioning:
• It can take up to four decades for a sea turtle to reach sexual maturity depending on the breed
• Sea turtles of breeding age can travel thousands of miles before they settle upon a location to lay their eggs, some may return to where they were hatched
• Mature females can lay eggs every two to four years
• The egg-laying and the disguising process takes the female about an hour to complete:
• The female digs a deep round hole to lay her eggs in (50 – 350 eggs)
• She then covers the eggs with sand and disguises the spot to prevent scavaging
• Oftentimes she creates fake beds to confuse predators
• Once the eggs have been laid and properly concealed the female returns to the ocean and the eggs are left to their own devices
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "The solar system consists of the Sun, eight planets, and their moons, along with asteroids, comets, and other celestial bodies. The planets are Mercury, Venus, Earth, Mars, Jupiter, Saturn, Uranus, and Neptune, each with unique characteristics and orbits around the Sun. The Sun, a star, provides light and heat to the solar system. Asteroids are rocky bodies found mainly between Mars and Jupiter, while comets are icy bodies that release gas and dust when they approach the Sun.",
"role": "user"
},
{
"content": "This passage describes the solar system, outlining its main components: the Sun, eight planets, moons, asteroids, comets, and other celestial bodies. It provides a brief overview of the planets, including their unique characteristics and orbits around the Sun. It also defines asteroids as rocky bodies primarily found between Mars and Jupiter and comets as icy bodies that release gas and dust upon approaching the Sun.",
"role": "assistant"
}
] |
Summarization
|
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gemini-1.5-flash-preview-0514
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Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: It takes decades for sea turtles to reach sexual maturity. Maturity may range from as early as 7 to 13 years for leatherbacks, 11 to 16 years for both species of ridleys, 20 to 25 years in hawksbills, 25 to 35 years for loggerheads, and 26 to 40 years in green sea turtles. Mature sea turtles may migrate thousands of miles to reach breeding sites. After mating at sea, adult female sea turtles return to land to lay their eggs. Different species of sea turtles exhibit various levels of philopatry. In the extreme case, females return to the same beach where they hatched. This can take place every two to four years in maturity. The mature nesting female hauls herself onto the beach, nearly always at night, and finds suitable sand in which to create a nest. Using her hind flippers, she digs a circular hole 40 to 50 centimeters (16 to 20 in) deep. After the hole is dug, the female then starts filling the nest with her clutch of soft-shelled eggs. Depending on the species, a typical clutch may contain 50–350 eggs. After laying, she re-fills the nest with sand, re-sculpting and smoothing the surface, and then camouflaging the nest with vegetation until it is relatively undetectable visually. She may also dig decoy nests. The whole process takes 30 to 60 minutes. She then returns to the ocean, leaving the eggs untended.
What does the passage say about sea turtles?
Response: This passage talks about the reproduction process of sea turtles specifically mentioning:
• It can take up to four decades for a sea turtle to reach sexual maturity depending on the breed
• Sea turtles of breeding age can travel thousands of miles before they settle upon a location to lay their eggs, some may return to where they were hatched
• Mature females can lay eggs every two to four years
• The egg-laying and the disguising process takes the female about an hour to complete:
• The female digs a deep round hole to lay her eggs in (50 – 350 eggs)
• She then covers the eggs with sand and disguises the spot to prevent scavaging
• Oftentimes she creates fake beds to confuse predators
• Once the eggs have been laid and properly concealed the female returns to the ocean and the eggs are left to their own devices
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "The human digestive system is a complex network of organs responsible for breaking down food into nutrients that the body can absorb. The process begins in the mouth, where food is chewed and mixed with saliva. It then travels down the esophagus to the stomach, where it is churned and mixed with gastric juices. Next, the food moves into the small intestine, where most nutrient absorption occurs. Finally, undigested waste is passed into the large intestine and eliminated from the body. The digestive system relies on various enzymes and hormones to break down food and regulate the process.",
"role": "user"
},
{
"content": "This passage explains the human digestive system, describing its role in breaking down food into absorbable nutrients. It outlines the stages of digestion, starting with chewing and mixing in the mouth, followed by churning and mixing with gastric juices in the stomach. It emphasizes the small intestine's role in nutrient absorption and the large intestine's role in eliminating undigested waste. It also highlights the importance of enzymes and hormones in facilitating digestion.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
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gemini-1.5-flash-preview-0514
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Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: In one or two sentences summarize how playing with children impacts relationships.
In addition to learning and developing new skills, playing with your young child is also quality time that brings you closer together.
“Play supports the formation of the safe, stable and nurturing relationships with all caregivers that children need to thrive,” the AAP report states.
Strong emotional connections with their parents and caring adults help children develop a secure attachment. Knowing they can count on their parent to be there when they need them gives a child the confidence to play freely, explore, try new things and learn.
“What they most need are interactions, language, give and take,” writes Dr. Perri Klass. “Which can just be another way of saying, somebody to play with.”
Response: Playing with children is quality time interacting together, which supports a secure attachment and safe, stable, and nurturing relationships. Having strong emotional connections supports children as they explore, learn, and try new things.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Summarize the key benefits of a healthy diet in one concise sentence.",
"role": "user"
},
{
"content": "A healthy diet provides essential nutrients, supports overall health, and reduces the risk of chronic diseases.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
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gemini-1.5-flash-preview-0514
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Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: In one or two sentences summarize how playing with children impacts relationships.
In addition to learning and developing new skills, playing with your young child is also quality time that brings you closer together.
“Play supports the formation of the safe, stable and nurturing relationships with all caregivers that children need to thrive,” the AAP report states.
Strong emotional connections with their parents and caring adults help children develop a secure attachment. Knowing they can count on their parent to be there when they need them gives a child the confidence to play freely, explore, try new things and learn.
“What they most need are interactions, language, give and take,” writes Dr. Perri Klass. “Which can just be another way of saying, somebody to play with.”
Response: Playing with children is quality time interacting together, which supports a secure attachment and safe, stable, and nurturing relationships. Having strong emotional connections supports children as they explore, learn, and try new things.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Explain the significance of the Industrial Revolution in one or two sentences.",
"role": "user"
},
{
"content": "The Industrial Revolution marked a period of rapid technological advancement and societal change, leading to mass production, urbanization, and economic growth.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
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gemini-1.5-flash-preview-0514
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Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: In one or two sentences summarize how playing with children impacts relationships.
In addition to learning and developing new skills, playing with your young child is also quality time that brings you closer together.
“Play supports the formation of the safe, stable and nurturing relationships with all caregivers that children need to thrive,” the AAP report states.
Strong emotional connections with their parents and caring adults help children develop a secure attachment. Knowing they can count on their parent to be there when they need them gives a child the confidence to play freely, explore, try new things and learn.
“What they most need are interactions, language, give and take,” writes Dr. Perri Klass. “Which can just be another way of saying, somebody to play with.”
Response: Playing with children is quality time interacting together, which supports a secure attachment and safe, stable, and nurturing relationships. Having strong emotional connections supports children as they explore, learn, and try new things.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "In a few sentences, describe the main functions of the circulatory system.",
"role": "user"
},
{
"content": "The circulatory system, comprised of the heart, blood vessels, and blood, is responsible for transporting oxygen and nutrients throughout the body, removing waste products, and regulating temperature.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
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gemini-1.5-flash-preview-0514
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Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: In one or two sentences summarize how playing with children impacts relationships.
In addition to learning and developing new skills, playing with your young child is also quality time that brings you closer together.
“Play supports the formation of the safe, stable and nurturing relationships with all caregivers that children need to thrive,” the AAP report states.
Strong emotional connections with their parents and caring adults help children develop a secure attachment. Knowing they can count on their parent to be there when they need them gives a child the confidence to play freely, explore, try new things and learn.
“What they most need are interactions, language, give and take,” writes Dr. Perri Klass. “Which can just be another way of saying, somebody to play with.”
Response: Playing with children is quality time interacting together, which supports a secure attachment and safe, stable, and nurturing relationships. Having strong emotional connections supports children as they explore, learn, and try new things.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Briefly summarize the concept of natural selection in evolutionary theory.",
"role": "user"
},
{
"content": "Natural selection, a key principle in evolution, states that organisms with traits best suited to their environment are more likely to survive and reproduce, passing on those advantageous traits to their offspring.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
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gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: In one or two sentences summarize how playing with children impacts relationships.
In addition to learning and developing new skills, playing with your young child is also quality time that brings you closer together.
“Play supports the formation of the safe, stable and nurturing relationships with all caregivers that children need to thrive,” the AAP report states.
Strong emotional connections with their parents and caring adults help children develop a secure attachment. Knowing they can count on their parent to be there when they need them gives a child the confidence to play freely, explore, try new things and learn.
“What they most need are interactions, language, give and take,” writes Dr. Perri Klass. “Which can just be another way of saying, somebody to play with.”
Response: Playing with children is quality time interacting together, which supports a secure attachment and safe, stable, and nurturing relationships. Having strong emotional connections supports children as they explore, learn, and try new things.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Explain the key differences between aerobic and anaerobic respiration in a concise way.",
"role": "user"
},
{
"content": "Aerobic respiration requires oxygen to produce energy, yielding more ATP, while anaerobic respiration occurs in the absence of oxygen, generating less energy and producing byproducts like lactic acid.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
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gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: In one or two sentences summarize how playing with children impacts relationships.
In addition to learning and developing new skills, playing with your young child is also quality time that brings you closer together.
“Play supports the formation of the safe, stable and nurturing relationships with all caregivers that children need to thrive,” the AAP report states.
Strong emotional connections with their parents and caring adults help children develop a secure attachment. Knowing they can count on their parent to be there when they need them gives a child the confidence to play freely, explore, try new things and learn.
“What they most need are interactions, language, give and take,” writes Dr. Perri Klass. “Which can just be another way of saying, somebody to play with.”
Response: Playing with children is quality time interacting together, which supports a secure attachment and safe, stable, and nurturing relationships. Having strong emotional connections supports children as they explore, learn, and try new things.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "In one or two sentences, summarize the impact of the printing press on society.",
"role": "user"
},
{
"content": "The invention of the printing press revolutionized communication and knowledge dissemination, leading to increased literacy, the spread of ideas, and the rise of a more informed public.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
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gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: In one or two sentences summarize how playing with children impacts relationships.
In addition to learning and developing new skills, playing with your young child is also quality time that brings you closer together.
“Play supports the formation of the safe, stable and nurturing relationships with all caregivers that children need to thrive,” the AAP report states.
Strong emotional connections with their parents and caring adults help children develop a secure attachment. Knowing they can count on their parent to be there when they need them gives a child the confidence to play freely, explore, try new things and learn.
“What they most need are interactions, language, give and take,” writes Dr. Perri Klass. “Which can just be another way of saying, somebody to play with.”
Response: Playing with children is quality time interacting together, which supports a secure attachment and safe, stable, and nurturing relationships. Having strong emotional connections supports children as they explore, learn, and try new things.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Briefly describe the central theme of Shakespeare's Hamlet.",
"role": "user"
},
{
"content": "Hamlet explores themes of revenge, mortality, and the complexities of human nature as Prince Hamlet grapples with the murder of his father and his own existential crisis.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: In one or two sentences summarize how playing with children impacts relationships.
In addition to learning and developing new skills, playing with your young child is also quality time that brings you closer together.
“Play supports the formation of the safe, stable and nurturing relationships with all caregivers that children need to thrive,” the AAP report states.
Strong emotional connections with their parents and caring adults help children develop a secure attachment. Knowing they can count on their parent to be there when they need them gives a child the confidence to play freely, explore, try new things and learn.
“What they most need are interactions, language, give and take,” writes Dr. Perri Klass. “Which can just be another way of saying, somebody to play with.”
Response: Playing with children is quality time interacting together, which supports a secure attachment and safe, stable, and nurturing relationships. Having strong emotional connections supports children as they explore, learn, and try new things.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Summarize the primary function of the immune system in a few sentences.",
"role": "user"
},
{
"content": "The immune system protects the body against disease-causing pathogens by recognizing and destroying harmful invaders, using a network of cells and organs to maintain internal health.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
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gemini-1.5-flash-preview-0514
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Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: In one or two sentences summarize how playing with children impacts relationships.
In addition to learning and developing new skills, playing with your young child is also quality time that brings you closer together.
“Play supports the formation of the safe, stable and nurturing relationships with all caregivers that children need to thrive,” the AAP report states.
Strong emotional connections with their parents and caring adults help children develop a secure attachment. Knowing they can count on their parent to be there when they need them gives a child the confidence to play freely, explore, try new things and learn.
“What they most need are interactions, language, give and take,” writes Dr. Perri Klass. “Which can just be another way of saying, somebody to play with.”
Response: Playing with children is quality time interacting together, which supports a secure attachment and safe, stable, and nurturing relationships. Having strong emotional connections supports children as they explore, learn, and try new things.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "In a concise statement, explain the concept of photosynthesis.",
"role": "user"
},
{
"content": "Photosynthesis is the process by which plants use sunlight, water, and carbon dioxide to produce glucose for energy and release oxygen as a byproduct.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
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gemini-1.5-flash-preview-0514
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Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: In one or two sentences summarize how playing with children impacts relationships.
In addition to learning and developing new skills, playing with your young child is also quality time that brings you closer together.
“Play supports the formation of the safe, stable and nurturing relationships with all caregivers that children need to thrive,” the AAP report states.
Strong emotional connections with their parents and caring adults help children develop a secure attachment. Knowing they can count on their parent to be there when they need them gives a child the confidence to play freely, explore, try new things and learn.
“What they most need are interactions, language, give and take,” writes Dr. Perri Klass. “Which can just be another way of saying, somebody to play with.”
Response: Playing with children is quality time interacting together, which supports a secure attachment and safe, stable, and nurturing relationships. Having strong emotional connections supports children as they explore, learn, and try new things.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Explain the main purpose of the digestive system in a few sentences.",
"role": "user"
},
{
"content": "The digestive system breaks down food into smaller molecules that the body can absorb and use for energy, growth, and repair. It consists of organs that work together to digest, absorb, and eliminate waste.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
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gemini-1.5-flash-preview-0514
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Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Provide a summary of this singular paragraph from an article on Batman. If possible, keep the summary to one single sentence.
Here is the paragraph:
Kane recognized three separate influences on the creation of Batman. The first was da Vinci’s model of a flying machine called the Ornithopter, created about 500 hundred years ago. The second was the movie The Mark of Zorro. “Zorro’s use of a mask to conceal his identity,” Kane writes, “gave me the idea of giving Batman a secret identity.” The third influence on Batman was a movie Kane saw the year before his attack by the Vultures: The Bat Whispers, an adaptation of a novel by Mary Roberts Rinehart. In the movie a detective tries to track down a mysterious killer, the Bat, and at the end of the film the detective is revealed to be the killer himself. His black robe and bat-shaped head made him look “very ominous” to Kane.
Response: The superhero Batman's design had 3 main influences; Da Vinci's model of a flying machine, the movie 'The Mark of Zorro', and a movie adaptation of the novel 'The Bat Whispers'.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Summarize the main points of this article about the history of the internet in a single sentence.",
"role": "user"
},
{
"content": "This article outlines the key milestones in the development of the internet, from its origins as a military research project to its transformation into a global communication network.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
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gemini-1.5-flash-preview-0514
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Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Provide a summary of this singular paragraph from an article on Batman. If possible, keep the summary to one single sentence.
Here is the paragraph:
Kane recognized three separate influences on the creation of Batman. The first was da Vinci’s model of a flying machine called the Ornithopter, created about 500 hundred years ago. The second was the movie The Mark of Zorro. “Zorro’s use of a mask to conceal his identity,” Kane writes, “gave me the idea of giving Batman a secret identity.” The third influence on Batman was a movie Kane saw the year before his attack by the Vultures: The Bat Whispers, an adaptation of a novel by Mary Roberts Rinehart. In the movie a detective tries to track down a mysterious killer, the Bat, and at the end of the film the detective is revealed to be the killer himself. His black robe and bat-shaped head made him look “very ominous” to Kane.
Response: The superhero Batman's design had 3 main influences; Da Vinci's model of a flying machine, the movie 'The Mark of Zorro', and a movie adaptation of the novel 'The Bat Whispers'.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Provide a brief summary of the key arguments presented in this research paper on climate change.",
"role": "user"
},
{
"content": "This research paper argues that human activities are the primary driver of climate change, presenting evidence of rising global temperatures, increased greenhouse gas emissions, and their impact on ecosystems.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
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gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Provide a summary of this singular paragraph from an article on Batman. If possible, keep the summary to one single sentence.
Here is the paragraph:
Kane recognized three separate influences on the creation of Batman. The first was da Vinci’s model of a flying machine called the Ornithopter, created about 500 hundred years ago. The second was the movie The Mark of Zorro. “Zorro’s use of a mask to conceal his identity,” Kane writes, “gave me the idea of giving Batman a secret identity.” The third influence on Batman was a movie Kane saw the year before his attack by the Vultures: The Bat Whispers, an adaptation of a novel by Mary Roberts Rinehart. In the movie a detective tries to track down a mysterious killer, the Bat, and at the end of the film the detective is revealed to be the killer himself. His black robe and bat-shaped head made him look “very ominous” to Kane.
Response: The superhero Batman's design had 3 main influences; Da Vinci's model of a flying machine, the movie 'The Mark of Zorro', and a movie adaptation of the novel 'The Bat Whispers'.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Summarize the main findings of this study on the effectiveness of a new cancer treatment.",
"role": "user"
},
{
"content": "This study found that the new cancer treatment significantly improved survival rates and reduced tumor size in patients with advanced cancer, indicating its potential as a promising therapy.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
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gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Provide a summary of this singular paragraph from an article on Batman. If possible, keep the summary to one single sentence.
Here is the paragraph:
Kane recognized three separate influences on the creation of Batman. The first was da Vinci’s model of a flying machine called the Ornithopter, created about 500 hundred years ago. The second was the movie The Mark of Zorro. “Zorro’s use of a mask to conceal his identity,” Kane writes, “gave me the idea of giving Batman a secret identity.” The third influence on Batman was a movie Kane saw the year before his attack by the Vultures: The Bat Whispers, an adaptation of a novel by Mary Roberts Rinehart. In the movie a detective tries to track down a mysterious killer, the Bat, and at the end of the film the detective is revealed to be the killer himself. His black robe and bat-shaped head made him look “very ominous” to Kane.
Response: The superhero Batman's design had 3 main influences; Da Vinci's model of a flying machine, the movie 'The Mark of Zorro', and a movie adaptation of the novel 'The Bat Whispers'.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "In one sentence, summarize the central theme of this short story about a young girl's journey to find her lost dog.",
"role": "user"
},
{
"content": "The short story explores themes of loss, resilience, and the unbreakable bond between a girl and her beloved pet as she embarks on a heartfelt quest to find her missing dog.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Provide a summary of this singular paragraph from an article on Batman. If possible, keep the summary to one single sentence.
Here is the paragraph:
Kane recognized three separate influences on the creation of Batman. The first was da Vinci’s model of a flying machine called the Ornithopter, created about 500 hundred years ago. The second was the movie The Mark of Zorro. “Zorro’s use of a mask to conceal his identity,” Kane writes, “gave me the idea of giving Batman a secret identity.” The third influence on Batman was a movie Kane saw the year before his attack by the Vultures: The Bat Whispers, an adaptation of a novel by Mary Roberts Rinehart. In the movie a detective tries to track down a mysterious killer, the Bat, and at the end of the film the detective is revealed to be the killer himself. His black robe and bat-shaped head made him look “very ominous” to Kane.
Response: The superhero Batman's design had 3 main influences; Da Vinci's model of a flying machine, the movie 'The Mark of Zorro', and a movie adaptation of the novel 'The Bat Whispers'.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Provide a concise summary of the main arguments presented in this debate on the future of artificial intelligence.",
"role": "user"
},
{
"content": "The debate revolves around the potential benefits and risks associated with the rapid advancement of artificial intelligence, with participants discussing its impact on employment, societal values, and ethical considerations.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Provide a summary of this singular paragraph from an article on Batman. If possible, keep the summary to one single sentence.
Here is the paragraph:
Kane recognized three separate influences on the creation of Batman. The first was da Vinci’s model of a flying machine called the Ornithopter, created about 500 hundred years ago. The second was the movie The Mark of Zorro. “Zorro’s use of a mask to conceal his identity,” Kane writes, “gave me the idea of giving Batman a secret identity.” The third influence on Batman was a movie Kane saw the year before his attack by the Vultures: The Bat Whispers, an adaptation of a novel by Mary Roberts Rinehart. In the movie a detective tries to track down a mysterious killer, the Bat, and at the end of the film the detective is revealed to be the killer himself. His black robe and bat-shaped head made him look “very ominous” to Kane.
Response: The superhero Batman's design had 3 main influences; Da Vinci's model of a flying machine, the movie 'The Mark of Zorro', and a movie adaptation of the novel 'The Bat Whispers'.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Summarize the key features of this new smartphone in a single sentence.",
"role": "user"
},
{
"content": "This new smartphone boasts a sleek design, a powerful processor, an impressive camera system, and innovative features like facial recognition and wireless charging.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Provide a summary of this singular paragraph from an article on Batman. If possible, keep the summary to one single sentence.
Here is the paragraph:
Kane recognized three separate influences on the creation of Batman. The first was da Vinci’s model of a flying machine called the Ornithopter, created about 500 hundred years ago. The second was the movie The Mark of Zorro. “Zorro’s use of a mask to conceal his identity,” Kane writes, “gave me the idea of giving Batman a secret identity.” The third influence on Batman was a movie Kane saw the year before his attack by the Vultures: The Bat Whispers, an adaptation of a novel by Mary Roberts Rinehart. In the movie a detective tries to track down a mysterious killer, the Bat, and at the end of the film the detective is revealed to be the killer himself. His black robe and bat-shaped head made him look “very ominous” to Kane.
Response: The superhero Batman's design had 3 main influences; Da Vinci's model of a flying machine, the movie 'The Mark of Zorro', and a movie adaptation of the novel 'The Bat Whispers'.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Provide a brief summary of the main arguments presented in this historical account of the American Revolution.",
"role": "user"
},
{
"content": "This historical account examines the political, social, and economic factors that led to the American Revolution, highlighting the colonists' struggle for independence from British rule.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Provide a summary of this singular paragraph from an article on Batman. If possible, keep the summary to one single sentence.
Here is the paragraph:
Kane recognized three separate influences on the creation of Batman. The first was da Vinci’s model of a flying machine called the Ornithopter, created about 500 hundred years ago. The second was the movie The Mark of Zorro. “Zorro’s use of a mask to conceal his identity,” Kane writes, “gave me the idea of giving Batman a secret identity.” The third influence on Batman was a movie Kane saw the year before his attack by the Vultures: The Bat Whispers, an adaptation of a novel by Mary Roberts Rinehart. In the movie a detective tries to track down a mysterious killer, the Bat, and at the end of the film the detective is revealed to be the killer himself. His black robe and bat-shaped head made him look “very ominous” to Kane.
Response: The superhero Batman's design had 3 main influences; Da Vinci's model of a flying machine, the movie 'The Mark of Zorro', and a movie adaptation of the novel 'The Bat Whispers'.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Summarize the main points of this scientific paper on the impact of plastic pollution on marine life.",
"role": "user"
},
{
"content": "This scientific paper highlights the devastating effects of plastic pollution on marine ecosystems, including ingestion, entanglement, and habitat destruction, leading to injuries, deaths, and disruptions in food webs.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Provide a summary of this singular paragraph from an article on Batman. If possible, keep the summary to one single sentence.
Here is the paragraph:
Kane recognized three separate influences on the creation of Batman. The first was da Vinci’s model of a flying machine called the Ornithopter, created about 500 hundred years ago. The second was the movie The Mark of Zorro. “Zorro’s use of a mask to conceal his identity,” Kane writes, “gave me the idea of giving Batman a secret identity.” The third influence on Batman was a movie Kane saw the year before his attack by the Vultures: The Bat Whispers, an adaptation of a novel by Mary Roberts Rinehart. In the movie a detective tries to track down a mysterious killer, the Bat, and at the end of the film the detective is revealed to be the killer himself. His black robe and bat-shaped head made him look “very ominous” to Kane.
Response: The superhero Batman's design had 3 main influences; Da Vinci's model of a flying machine, the movie 'The Mark of Zorro', and a movie adaptation of the novel 'The Bat Whispers'.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "In one sentence, summarize the central theme of this play about a family grappling with grief and loss.",
"role": "user"
},
{
"content": "The play explores themes of grief, forgiveness, and family bonds as characters navigate the complexities of loss and strive to find meaning and healing.",
"role": "assistant"
}
] |
Summarization
|
gemini-1.5-flash-preview-0514
|
gemini-1.5-flash-preview-0514
|
Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.
Example pair:
Instruction: Provide a summary of this singular paragraph from an article on Batman. If possible, keep the summary to one single sentence.
Here is the paragraph:
Kane recognized three separate influences on the creation of Batman. The first was da Vinci’s model of a flying machine called the Ornithopter, created about 500 hundred years ago. The second was the movie The Mark of Zorro. “Zorro’s use of a mask to conceal his identity,” Kane writes, “gave me the idea of giving Batman a secret identity.” The third influence on Batman was a movie Kane saw the year before his attack by the Vultures: The Bat Whispers, an adaptation of a novel by Mary Roberts Rinehart. In the movie a detective tries to track down a mysterious killer, the Bat, and at the end of the film the detective is revealed to be the killer himself. His black robe and bat-shaped head made him look “very ominous” to Kane.
Response: The superhero Batman's design had 3 main influences; Da Vinci's model of a flying machine, the movie 'The Mark of Zorro', and a movie adaptation of the novel 'The Bat Whispers'.
Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context.
Store the generated pairs in JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance:
{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]}
Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.
|
[
{
"content": "Provide a concise summary of the main arguments presented in this philosophical essay on the nature of consciousness.",
"role": "user"
},
{
"content": "This philosophical essay delves into the nature of consciousness, exploring various theories and perspectives on the subjective experience of being aware, thinking, and feeling.",
"role": "assistant"
}
] |
Summarization
|
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