def summarize(self, interval, bins=None, method='summarize',
                  function='mean'):

        # We may be dividing by zero in some cases, which raises a warning in
        # NumPy based on the IEEE 754 standard (see
        # http://docs.scipy.org/doc/numpy/reference/generated/
        #       numpy.seterr.html)
        #
        # That's OK -- we're expecting that to happen sometimes. So temporarily
        # disable this error reporting for the duration of this method.
        orig = np.geterr()['invalid']
        np.seterr(invalid='ignore')

        if (bins is None) or (method == 'get_as_array'):
            bw = BigWigFile(open(self.fn))
            s = bw.get_as_array(
                interval.chrom,
                interval.start,
                interval.stop,)
            if s is None:
                s = np.zeros((interval.stop - interval.start,))
            else:
                s[np.isnan(s)] = 0

        elif method == 'ucsc_summarize':
            if function in ['mean', 'min', 'max', 'std', 'coverage']:
                return self.ucsc_summarize(interval, bins, function=function)
            else:
                raise ValueError('function "%s" not supported by UCSC\'s'
                                 'bigWigSummary')

        else:
            bw = BigWigFile(open(self.fn))
            s = bw.summarize(
                interval.chrom,
                interval.start,
                interval.stop, bins)
            if s is None:
                s = np.zeros((bins,))
            else:
                if function == 'sum':
                    s = s.sum_data
                if function == 'mean':
                    s = s.sum_data / s.valid_count
                    s[np.isnan(s)] = 0
                if function == 'min':
                    s = s.min_val
                    s[np.isinf(s)] = 0
                if function == 'max':
                    s = s.max_val
                    s[np.isinf(s)] = 0
                if function == 'std':
                    s = (s.sum_squares / s.valid_count)
                    s[np.isnan(s)] = 0

        # Reset NumPy error reporting
        np.seterr(divide=orig)
        return s
dataset/ETHPy150Open daler/metaseq/metaseq/filetype_adapters.py/BigWigAdapter.summarize/original