 supporting information files. The PLOS Biology Editors remain concerned about the integrity issues surrounding the preparation of Fig 0B, which suggest that rectangular portions of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the underlying gel image for Fig 0B (S0 File). The underlying data to support the conclusions of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and 