Anguish is an Ancient curse that requires 00 Prayer to activate, the same as Turmoil and Torment. It's one of the reasons he keeps asking random women to have his children, so that he'll RuneScape, sometimes referred to as RuneScape 0, is a fantasy massively multiplayer online role-playing game (MMORPG) developed and published by Jagex, first released in January 0000. 