 seem to support the other results reported in the figure, supporting that the image were spliced or otherwise manipulated in these areas. Instead, the authors have provided data from replicate experiments in the Supporting Information S0, S0, S0 and S00 Files below that seemingly support their conclusions. The underlying data provided to address these concerns seem to support the conclusions of the article, given that original files were not available for assessment in a number of instances and the integrity issues surrounding the preparation of Fig 0B, although the PLOS Biology Editors