 The thing about dhea is theres no telling which pathway its going to slide down and what it will create. Personally after about a week of backfilling my dhea pathways (in which it worked effectively and I felt great) it began to just convert to estrogen estrogen and more estrogen. For a lot of people I think this is the case. And its hard to get rid of the problem even with an ai and you stopped using it. It seems to create a cascade of estrogen. Pregnenolone, now thats a different story for me personally. Best thing ive added to my trt test dose. The thing about pregnenolone and dhea is there's now way to know how it will react or which hormones they will create once in the body. They are known as "parent" hormones responsible for the production of other hormones in the body including cortisol and estrogen which in high doses is no bueno. 