 aDepartment of Molecular Genetics, University of Toronto, Toronto, ON, Canada M0S 0A0; bDepartment of Chemistry, University of Toronto, Toronto, ON, Canada M0S 0A0; cDepartment of Biochemistry, University of Toronto, Toronto, ON, Canada M0S 0A0; Find this author on Google Scholar Find this author on PubMed Search for this author on this site Al