Which of the following carcinoma most frequently metastasizes to brain -
Small cell carcinoma lung
Prostate cancer
Rectal carcinoma
Endometrial cancer
Ans. is 'a' i.e., Small cell carcinoma of lung Frequency of Nervous system metastasis by common primary tumour. Site of primary tumourBrain %MetastasesLeptomeningeal % MetastasisSpinal cord % CompressionLung402418Breast194124Melanoma10124Gastrointestinal tract7136Genitourinary tract7-18Others171030
Clinical Aspects of Neoplasia