Which of the following is/are not feature(s) of rheumatoid ahritis
Pannus formation in joint
Osteosclerosis osteoclastic activity in underlying bone
Erosion of cailage
Osteophyte
Ans. d. OsteophyteThe characteristic histologic features include :Infiltration of synol stroma by dense perivascular inflammatory cells, consisting of B cells and CD4+ helper T, plasma cells and macrophages;Increased vascularity owing to vasodilation and angiogenesis, with superficial hemosiderin deposits;Aggregation of organizing fibrin covering poions of the synovium and floating in the joint space as rice bodies;Accumulation of neutrophils in the synol fluid and along the surface of synovium but usually not deep in the synol stroma;Osteoclastic activity in underlying bone, allowing the synovium to penetrate into the bone forming juxta-aicular erosions, subchondral cysts, and osteoporosis;Pannus formation- Pannus is a mass of synovium and synol stroma consisting of inflammatory cells granulation tissue, and fibroblasts, which grows over the aicular cailage and causes its erosion.