Patient presenting with cutaneous vasculitis, glomerulonephritis, peripheral neuropathy, which of the following will help in diagnosis?
ANCA
RA factor
Hbsag
MIF
Ref. API Textbook of Medicine. Pg. 1313
 
Cutaneous vasculitis features – Diagnosis
Anti-neutrophil cytoplasmic antibodies (ANCAs):

Group of autoantibodies
IgG type mainly,
Produced against antigens in cytoplasm of neutrophil granulocytes & monocytes.
Particularly associated with systemic vasculitis, so called “ANCA-associated vasculitis”.
c-ANCA – Abs against MPO, p-ANCA -  Abs Against PR3