A 35-year-old lady complains of dysphagia, Raynaud's phenomenon and her hands show the following appearance. Investigations show positive ANA. The likely diagnosis is
Systemic lupus erythematosus
Systemic sclerosis
Mixed connective tissue disorder
Rheumatoid ahritis
Systemic sclerosisThe chronic disease is characterized by:1.c/c inflammation, d/t autoimmunity2.Widespread damage to small blood vesselsProgressive interstitial & perivascular fibrosis in skin & multiple organsReference: Harrison&;s principles of Internal Medicine; 19th edition
General pathology