The clinically relevant dose of neuromuscular blocker required for clinically useful relaxation corresponds to:-
ED50
ED75
ED95
ED25
The effect of neuromuscular blocking drugs is measured as the depression of adductor muscle contraction (twitch) following electrical stimulation of the ulnar nerve. The value is compared with a control value obtained before injection of the drug. According to Miller, potency of a NMBD is best described as the effective dose - "The dose of a neuromuscular blocking drug required to produce an effect (e.g., 50%, 90%, or 95% depression of twitch height, commonly expressed as ED50, ED90, and ED95, respectively". Thus, the ED95 is the amount of NMBD required to reduce twitch height by 95% i.e . clinically useful relaxation
Neuromuscular Blocker