What is the impact on fetus in case of use of Indomethacin in utero in third trimester?
Patent ductus aeriosus
Early closure of ductus aeriosus
Ventricular septal defect
Atrial septal defect
Prostaglandins helps to keep ductus aeriosus open. Indomethacin inhibits prostaglandins levels | So, closure of ductus aeriosus | DOC for PDA
Valvular hea diseases