Antidote for organophosphates poisoning are all except: September 2009 March 2013 (b, d)
Physostigmine
Activated charcoal
Pralidoxime
Atropine
Ans. A: Physostigmine The mainstays of medical therapy in organophosphate (OP) poisoning include ? Atropine-arrests muscarinic effects, Pralidoxime (2-PAM)-acts by competing for the phosphate moiety of the organophosphorus compound and release it from the cholinesterase enzyme Benzodiazepines (e.g., diazepam)-For convulsions Intravenous glycopyrrolate or diphenhydramine may provide an alternative centrally acting anticholinergic agent used to treat muscarinic toxicity if atropine is unavailable or in limited supply