Which of the following is true for phosphofructokinase?
It uses Fructose 1,6 bisphosphate as substrate.
It generates ATP
It catalyses an irreversible reaction in glycolysis
It is activated by increased levels of ATP and citrate.
Phosphofructokinase catalyses the first committed step of glycolysis. It is the rate limiting enzyme of glycolysis. The reaction is irreversible.