Mc-Callum's patch is diagnostic of -
Infective endocarditis
Rheumatic endocarditis
Myocardial infarction
Tetralogy of Fallot (TOF)
(B) (Rheumatic endocarditis) (Robbin's 8th edpg. 566)Pathological features of Rheumatic carditis1. Acute Rheumatic carditisThere is diffuse inflammation and aschoff bodies in any of the three layers of heart - pancarditisa) Pericardium - Fibrinous or serofibrinous pericarditis also known as "bread and butter" pericarditis. Pericarditis generally resolve without sequelae.b) Myocardium - Diffuse non-specific myocarditis with Aschoff bodies.c) Endocardium - Small warty projections, i.e. verucae along the line of closure on the valvular leaflets (especially on left side mitral valve).2. Chronic rheumatic carditis* Chronic RHD is characterized by organization of the acute inflammation and subsequent fibrosis.* In particular, the valvular leaflets becomes involved and characterized by-- Leaflet thickening- Commissural fusion- Shortening, thickening and fusion of chordae tendinae.* Fibrous bridging across the valvular commissures and calcification create "fish mouth" or''Buttonhole" stenosis.* Mitral valve is involved most commonly.* RHD is the most common cause of mitral stenosis.* Aortic valve is second commonest valve to involve.* Tricuspid valve may also be involved.* Irrigular thickening of the posterior wall of left artrium - MacCallum plaque.* MacCallum plaque is due to subendothelial collection of Aschoff nodules.* Most frequent cardiac tumour for all age group is metastasis* Most frequent primary cardiac tumor - Myxoma.* Most frequent primary cardiac tumour in infants and children is Rhabdomyoma.
C.V.S