In Huntington chorea the causative mutation in the protein huntingtin is a:
Point mutation
Gene deletion
Frameshift mutation
Trinucleotide repeat expansion
Huntington disease (HD) Mutation in the HTT gene which codes for protein called huntingtin which is impoant to neurons. The HTT mutation involves a DNA segment known as a CAG trinucleotide repeat. Made up of a series of three DNA building blocks (cytosine, adenine, and guanine) that appear multiple times in a row leading to the disease.
Genetics