All of the following statements about penicillin G are true EXPCEPT:
It is actively secreted in tubules
It is never administered orally
It is effective against gram positive as well as some gram negative bacteria
It acts by inhibiting cell wall synthesis
penicillin G is acid labile-destroyed by gastric acid. As such, less than 1/3rd of an oral dose is absorbed in the active form. Absorption of sod. PnG from i.m. site is rapid and complete; peak plasma level is attained in 30 min. ESSENTIALS OF PHARMACOLOGY page no. 718
Chemotherapy