False about kernicteres is -
No long term effect
Occurs with bilirubin more than 25 mg %
Deposition in basal ganglion
Opisthotonus
Ans. is 4aT i.e., No long term effect Kernicteruso Also known as bilirubin encephalopathy.o Resulting from deposition of indirect bilirubin in basal ganlion and brain stem nuclei,o Usually appear 2-5 days after birth.o Usually have long term sequale like movement disorder (choreoathetosis, ballismus tremor) sensorineural hearingloss.Clinical Features of kernicterusACUTEFORMPhase 1 (1st 1-2 days): poor sucking, stupor, hypotonia, seizuresPhase 2 (middle of 1 st wk): hypertonia of extensor muscles, opisthotonos, retrocollis, feverPhase 3 (after the 1 st wk): hypertoniaCHRONIC FORMFirst year: hypotonia, active deep tendon reflexes, obligatory tonic neck reflexes, delayed motor skills.After 1st yr: movement disorders (choreoathetosis, ballismus, tremor), upward gaze, sensorineural hearing loss.
Liver and Biliary System