ELISA is performed on a population with low prevalence, What would be the result of performing double screening ELISA tests-
Increased sensitivity and positive predictive value
Increased sensitivity and negative predictive value
Increased specificity and positive predictive value
Increased specificity and negative predictive value
Ref: Parks 23rd edition pg 139 Double ELISA meaning screening test is done in series. Series screening test : Sensitivity decreases Specificity increases PPV increases NPV decreases
Screening