Sickle cell anemia is the clinical manifestation of homozygous genes for an abnormal hemoglobin molecule. The event responsible for the mutation in the B chain is:
Insertion
Deletion
Nondisjunction
Point mutation
Ans. D. Point mutationThe mutation in HbS is an example ofPoint mutationPartially acceptable mis-sense mutationTransversionBase substitution.Nonconservative mutation
Molecular Genetics