A 30-year-old man presents with hematuria. His examination is normal except for an elevated blood pressure of 164/94 mm Hg. An ultrasound of the kidneys reveals multiple renal cysts in both kidneys. His father had a similar condition. Which of the following is not associated with this syndrome?
liver cysts
intracranial aneurysms
autosomal dominant inheritance
rheumatoid arthritis (RA)
RA is not associated with polycystic kidney disease. It has an autosomal dominant inheritance and about 50% develop renal failure by age 60 years. Cysts are also seen in the liver (more common) and pancreas. Also 5-10% of asymptomatic patients can have cerebral aneurysms. Renal transplantation is utilized in end-stage renal failure (ESRF). The transplanted kidney cannot be affected by the disease.
Kidney