Indicate the drug which does not improve lower esophageal sphincter tone or prevent gastroesophageal reflux, but is used as the first line treatment of gastroesophageal reflux disease:
Sodium alginate+aluminium hydroxide gel
Omeprazole
Mosapride
Metoclopramid
(Ref: KDT 6/e p648) Treatment of GERD can be acomplished by Increasing GI motility with prokinetic drugs (like metoclopramide and mosapride) or By decreasing gastric acid secretion with PPIs like omeprazole.
Other topics and Adverse effects