All the following statements are true, except?
Dipyridamole shows coronary steel phenomena
Omeprazole inhibit CYP 2C19
SNRI are drug of choice for severe depression
Agranulocytosis is the most common side effect of clozapine
Side effects of clozapine- Agranulocytosis (dose independent)- Seizures (dose dependent)- Sedation (m/c)- Myocarditis * Clopidogrel & ticlopidine both are prodrugs (inactive)* Activated by CYP 2C19* Omeprazole inhibits CYP2C19* Reversible P2Y12 inhibitors - cangrelor, ticagrelor SNRI (|5H & |NA), DOC for severe depression- Venlafaxine- Duloxetine- Milanacipran- Des venlafaxine- Levo milanacipran. Coronary steel phenomena shown by- Hydralazine- Isoflurane- Dipyridamole- Enflurane
Psychiatric Illness