Hereditory spherocytosis is due to deficiency of-
Ankyrin
Actin
Selectin
Integrin
HS is caused by diverse mutations that lead to an insufficiency of membrane skeletal components. The pathogenic mutations most commonly affects ankyrin, band 3, spectrin, or band 4.2. Ref :Robbins pathologic basis of disease ; south east asia edition ;pg:633
Haematology