Electron microscopy finding indicating irreversible cell injury is:
Dilation of ER
Dissociation of ribosomes from rough ER
Flocculent densities in the mitochondria
Intact cell membrane
Irreversible injury is associated morphologically with:- Mitochondrial swelling Plasma membrane damage which forms myelin figures Lysosomal swelling. Large, flocculent, amorphous densities develop in the mitochondrial matrix
Irreversible cell Injury/Necrosis