E6, E7 genes of which virus are implicated in oncogenesis ?
EBV
CMV
HTLV- 1
HPV
Ans. is 'd' i.e., HPV HPV selectively infects the epithelium of skin and mucous membrane and may immoalize the keratinocytes leading either asymptomatic infection, or was or neoplasia. Products of E-genes (E6, E7) are related to immoalization or malignant transformation of keratinocytes by interfering with p53 and Rb genes, respectively.