The complementarity-determining regions are-
Restricted to light chains
Are in the constant pa of the Ig molecule
Binds to Fc receptor
Are concerned in antigen recognition
In the variable region of the H and L domains, maximum sequence variation is concentrated in a few discrete regions called hyperevariable regions ( HV) . HV regions form the antigen binding site of the antibody molecule which is complementary to the structure of the epitope and are called Complementary Determining Regions (CDRs)
Immunology Pa 1 (Immune Response, Antigen-Antibody Reactions, Hypersensitivity, Structure of Immune System, Immunodeficiency Disorders)