A 5-yr old boy presents with pubic hair development. He is tall and has increased pigmentation of his genitalia and phallic enlargement. Blood pressure is 130/90 mm 14g. Measurement of which of the following hormones would be most likely to be diagnostic?
Increase 17 beta hydroxyl progesterone
Increase coisol
Increase aldosterone
Increase 11 deoxycoisol
Ans is 'd' i.e., Increase 11 deoxycoisol o Presence of Precocious pubey in a male child and hypeension (BP of 130/80 in a 5 year old child is considered hypeension) suggests a diagnosis of congenital adrenal Hyperplasia due to 11-13 Hydroxylase deficiency. o levels and excretion of 11 deoxycoisol is increased(see flow cha of previous explanations).