A 12-year-old intellectually disabled boy having short stature, protuberant abdomen with umbilical hernia, prominent forehead. His vision is normal. His parents are normal. What is metabolic defect in this disorder?
L-Iduronidase
Iduronate Sulfhatase
Aryl Sulfatase B
Beta Glucoronidase
Ans. B. Iduronate Sulfatase* Hunters Disease (MPS-II)* Distinguishing features are vision normal as there is no corneal clouding. Males are affected
Lipids