Recalcitrant acne is treated by:
Oral erythromycin
Oral tetracycline
Retinoids
Steroids
The European S3 guidelines recommend isotretinoin for the treatment of severe recalcitrant acne or moderate acne that has failed to respond to conventional antibiotic therapies. Retinoids - Isotretinoin : D.O.C for severe / gd 4 / nodulocystic acne/ acne conglobata. Dose 0.5 - 1 mg / kg body weight to be given till cumulative dose of 120-150mg/kg body weight.
Acne and chemical peeling