Which is the most active single chemotherapeutic agent in the treatment of leiomyosarcoma?
Adriamycin
Daunorubicin
Methotrexate
Cisplatin
Ans. (A) Adriamycin(Ref: KDT 8th/e p926)Doxorubicin (adriamycin) and daunorubicin are anthracycline derivatives.Daunorubicin is mainly used for hematological malignancies (acute leukemia) whereas doxorubicin is used for solid tumors and soft tissue sarcomas.
Chemotherapy: General Principles