Rapid diagnosis of rabies is made with?
Skin biopsy with fluorescent antibody testing
Rabies virus specific antibodies
Inoculation in mouse
Corneal impression smear
Biopsy is taken from nape of neck, rabies virus present in hair follicle. Rabies-Lab Diagnosis Rabies Antigens or Nucleic Acids detection: Immunofluorescence or immunoperoxidase staining Biopsy specimen from skin of the neck at hairline Impression preparations of brain or cornea tissue Negri bodies in the brain-80% positivity -PCR test on brain tissue specimen Viral Isolation Tissue is inoculated intra-cerebrally into suckling mice Serology Serum / CSF anti-rabies Ab by immunofluorescence Animal observation
viral infection