The most common condition of inherited blindness to mitochondrial chromosomal anomaly is
Retinopathy of prematurity
Leber's Hereditary optic neuropathy
Retinitis pigmentosa
Retinal detachment
(Lebers hereditary optic neuropathy) Leber's hereditary optic neuropathy (LHON) * Which is result of maternal mitochondria] DNA mutations 34660, 14484, 1778 and 15257) * The majority of patients are males in their twenties with the 11778 mutation, which carries worst prognosis * Diagnosis of any patients with bilateral] optic neuritis, painless visual loss * Telangiectatic female relatives