Histological difference between ulcerative colitis and Crohn's disease is presence of:-
Crypt abscess
Diffuse distribution of pseudopolyps
Mucosal edema
Lymphoid aggregates in the mucosa
Among the given options Diffuse distribution of pseudo polyps- occurs in Ulcerative colitis > Crohn's Mucosal edema - occurs in both (UC&CD) Lymphoid aggregates - occurs in both Crypt abscesses - Most characteristic lesion of UC Crypt abscess: Collection of neutrophils fill and expand the lumina of individual crypts of Lieberkuhn Crypt abscesses are not specific for UC and can be seen in Crohn's disease . Crohn's Disease Clinical Features - MC symptom is intermittent and colicky abdominal pain, most commonly noted in the lower abdomen. Diarrhea is the next most frequent symptom and is present, at least intermittently, in about 85% of patients.. Main intestinal complications of Crohn's disease include obstruction and perforation. Fistulas occur between the sites of perforation and adjacent organs, usually at the site of a previous laparotomy. In Crohn's disease, ileum is the MC site of fistula (enterocutaneous and enterovesical), MC site of perforation and MC site of carcinoma.
NEET 2019