All of following statements about are true about 6-mercaptopurine EXCEPT:
It is metabolized by xanthine osidase
It does not cause hyperuricemia
Its dose should be reduced when allopurinol is given concurrently
It is an active metabolite of azathioprine
(Ref: KDT 6/e p823, 824) All anticancer drugs can result in hyperuricemia by causing the destruction of excess cells. Azathioprine is an immunosuppressant drug that acts by generating 6-MP
Other topics and Adverse effects