All of the following are true for patients with ulcerative colitis associated with primary sclerosing cholangitis (PSC), Except
The may develop biliary cirrhosis
May have raised alkaline phosphatase
Increased risk of hilar Cholangiocarcinoma
PSC reves after a total colectomy
PSC associated with ulcerative colitis eventually leads to biliary cirrhosis. Investigations reveal a cholestatic pattern in LFT with an elevation of serum alkaline phosphatase & gamma-glutamyltransferase. The prevalence of cholangiocarcinoma in patients with PSC ranges from 7 to 13%. Reference: Bailey & love&;s sho practice of surgery,25th edition, page no:1127; SRB&;s manual of surgery,5th edition, page no:658.
G.I.T