Conversion of norepinephrine to epinephrine occur by
Methylation
Decarboxylation
Oxidation
Sulphation
Synthesis of NA occurs in all adrenergic neurons while that of adrenaline occurs only in the adrenal medullary cells. It requires a high concentration of glucocoicoids reaching through the intra- adrenal poal circulation for induction of the methylating enzyme - N methyltransferase. From essential of medical pharmacology K D Tripati 7th edition Page no 124
Autonomic nervous system