True about GIST all except
Most common in duodenum
Necrosis and ulceration present
PET is used to assess response to therapy
Well circumscribed
.GIST (Gastrointestinal stromal tumour) is rare but most common non epithelial small bowel tumours. * 25% of GIST occurs in small bowel (stomach - 50 to 60%). It is 0.2% of all GI tumours. * It is equal in both sexes * It arises from interstitial cell of Cajal. * More than 95% show c-kit (transmembrane receptor tyrosine kinase) mutation. * Many mesenchymal tumours of small bowel are now classified as GIST. GIST attains massive size when presenting clinically. * Palpable mass, compression, haemorrhage are the features. * CT is diagnostic. ref:SRB&;s manual of surgery,ed 3,pg no 812
G.I.T