A 35-year-old woman presents with 6-month history of skin rash and fatigue. Physical examination shows pallor and a necrotizing erythematous skin rash of her lower body. Laboratory studies reveal mild anemia and fasting blood glucose of 160 mg/dL. A CT scan of the abdomen demonstrates a 2-cm mass in the pancreas. Which of the following is the most likely diagnosis?
Carcinoid tumor
Gastrinoma
Glucagonoma
Insulinoma
Necrotizing migratory erythema develops in association with the hypersecretion of glucagon by alpha cell-containing tumors (glucagonomas). These patients also have mild hyperglycemia and anemia. The other choices do not present with these clinical signs and symptoms.Diagnosis: Glucagonoma
Pancreas