C-MYC translocation is seen in which of the following tumors?
Burkitt lymphoma
Neuroblastoma
Malignant melanoma
Breast cancer
All forms of Burkitt lymphoma are highly associated with translocation of the MYC gene on chromosome 8 that lead to increased MYC protein levels.The translocation paner for MYC is usually the IgH locus but may also be the Ig . Ref :Robbins pathologic basis of disease ; south east asia edition ;pg:597
Haematology