Drugs that can be used in opioid de-addiction are?
Clonidine
Diazepam
Methadone
All of the above
All of the drugs can be used. Methadone is effective orally, more potent ,longer acting and prevents withdrawal symptoms because it is slowly released from tissues. Clonidine a central alpha 2agonist can suppress autonomic.if withdrawal symptoms such as nausea, vomiting, anxiety and diarrhea. Night time sedation with a hypnotic like diazepam is helpful. Ref KD Tripathi 8th ed
Central Nervous system