In atherosclerosis, increased LDL in monocyte macrophage due to:
LDL receptors on macrophage
LDL receptors on endothelium
Lipids in LDL get oxidized
All of the above
Ans. (c) Lipids in LDL get oxidized(Ref: Robbins 9th/pg 496; 8th/pg 500)With chronic hyperlipidemia, lipoproteins accumulate within the intima, there they aggregate and become oxidized by free radicals produced by inflammatory cells.
Blood Vessels