All of the following statements about Nesidioblastosis are true, Except -
Hypoglycemic episodes may be seen
Occurs in adults more than children
Histopathology shows hyperplasia of islet cells
Diazoxide may be used for treatment
An insulinoma--an insulin-secreting pancreatic islet b-cell tumor--is the prototypical cause of endogenous hyperinsulinism and therefore should be sought in patients with a compatible clinical syndrome. However, insulinoma is not the only cause of endogenous hyperinsulinism. Some patients with fasting endogenous hyperinsulinemic hypoglycemia have diffuse islet involvement with b-cell hyperophy and sometimes hyperplasia. This pattern is commonly referred to as nesidioblastosis, although b-cells budding from ducts are not invariably found. Ref Harrisons internal medicine 20e p2887
Oncology