Which of the following is the most specific and sensitive screening test for renovascular hypeension?
HRCT
CT Angiography
Captopril enhanced radionucleotide scan
Doppler ultrasound of renal aeries
Hypeension due to an occlusive lesion of a renal aery is renovascular hypeensionIn the initial stages, the mechanism of hypeension generally is related to activation of the renin-angiotensin system. Obstruction of the renal aery leads to decreased renal perfusion pressure, thereby stimulating renin secretion. Over time, possibly as a consequence of secondary renal damage, this form of hypeension may become less renin-dependent.As a screening test, renal blood flow may be evaluated with a radionuclide -ohoiodohippurate (OIH) scan, or glomerular filtration rate may be evaluated with a - diethylenetriamine pentaacetic acid (DTPA) scan before and after a single dose of captopril (or another ACE inhibitor).Contrast aeriography remains the "gold standard" for evaluation and identification of renal aery lesions.Harrison 19e pg: 1618
All India exam