In acute exacerbations of COPD, noninvasive positive pressure ventilation (NIPPV) is initiated when
Paco2 >45 mmHg
PaO2 <80 mmHg
FEV1 <30
FEV1/FVC <0.7
In acute exacerbations of COPD, noninvasive positive pressure ventilation (NIPPV) is initiated in patients with respiratory failure, which is defined as Paco2 > 45 mmHg, This results in a significant reduction in moality rate, need for intubation, complications of therapy, and hospital length of stay.Ref: Harrison 19e pg: 1707
Respiratory system