A male infant presented with distension of abdomen shortly after birth with passing of less meconium. Subsequently a full-thickness biopsy of the rectum was performed. The rectal biopsy is likely to show:
Fibrosis of submucosa
Lack of ganglion cells
Thickened muscularis propria
Hyalinization of the muscular coat
b. Lack of ganglion cells(Ref: Nelson's 20/e p 1894-1897, Ghai 8/e p 285-286)"Whenever neonate presents with delayed passage of stool, Hirschsprung's disease should be suspected".
Stomach and Intestines