True statement about ductus aeriosus is:
It undergoes anatomic closure within 24 hours of bih
It connects aoa with pulmonary vein
It is induced to close by high levels of prostaglandins
May cause a machinery murmur by its patency
IMPOANT POINTS ABOUT DUCTUS AERIOSUS: - Physiological closure: occurs almost immediately after bih by contraction of muscular wall - Anatomic closure: occurs by proliferation of intima in 10-21 days after bih - After obliteration, it forms ligamentum aeriosum. - Murmur due to PDA - Continuous machinery murmur. - Ductus aeriosus is kept open with the help of prostaglandins in ductus dependent conditions Note : Prostaglandin inhibitors are used to close the ductus aeriosus. Intravenous (IV) indomethacin or ibuprofen is used to treat patent ductus aeriosus (PDA) in premature infants.
Acyanotic congenital hea diseases