Primary hyperaldosteronism what is seen
Hyperkalemia
Hyponatremia
Maetabolic alkolosis
Fall in aldosterone with sodium loading
The clinical hallmark of mineralocoicoid excess is hypokalemic hypeension Due to excess mineralocoicoid action lead to potassium and H+ depletion sodiu retention Serum sodium tends to normal due to concurrent fluid retention Because of h+ depletion lead to metabolic alkalosis Clinical features: 1) hypokalemia 2) hypeension at young age generally <40 3) metabolic alkalosis 4)muscle cramps in severe case tetany due to metabolic alkalosis
Endocrinology