All are true about nephronophthisis except:
Interstitial fibrosis
Coical tubular hyperophy
Cysts in the medulla
20% cases are non-familial
2 types of cystic disease affecting the renal medulla are : 1. Medullary sponge kidney Relatively common Usually innocuous condition Associated with nephrolithiasis 2.Nephronophthisis- Medullary cystic disease complex Associated with renal dysfunction. Cause of chronic kidney disease that usually begins in childhood. Coical tubulointerstitial damage and not hyperophy occurs in nephronophthisis.
Kidney disorders