Clonus is due to?
Upper motor neuron damage
Lower motor neuron damage
Extrapyramidal damage
Cerebellar damage
Ans. A Upper motor neuron damageRef: Ganong, 25th ed. pg. 233Clonus is characterized by repeated rhythmic contractions of muscle subjected to sudden maintained stretch.It is Caused by* Increased Gamma motor neuron discharge* Spinal cord injury causing damage to Renshaw cell which is an inhibitory inter-neuron.Conditions in Which Clonus is seen:1. Amyotrophic lateral sclerosis2. Stroke3. Multiple sclerosis4. Spinal cord damage5. Hepatic encephalopathyClonazepam and botulinum toxin is useful in management of clonus.
Nervous System