Alpha feto protein is increased in:
Hepatoblastoma
Neuroblastoma
Seminoma
Renal cell carcinoma
IIepatoblastoma Alpha feto protein is elevated in almost all hepatoblastomas and is used in its diagnosis and monitoring. Other carcinomas in which alpha feto protein is elevated are: - Hepatocellular carcinoma - Germ cell tumor of testis (non-seminomas) Non-neoplastic conditions in which alpha feto protein is raised: - Cirrhosis - Hepatitis - Pregnancy Remember - Elevated AFP levels are also found less regularly in carcinomas of lung, colon and pancreas - AFP is a glycoprotein