Mechanism of action of propylthiouracilin hypehyroidism is:
Inhibition of organification of iodine
Inhibition of oxidation of iodine
Inhibition of coupling of two DIT residues
All of the above
(Ref: KDT 6/e p248) Propylthiouracil, carbimazole and methimazole act by inhibiting the enzyme, thyroid peroxidase. It catalyses: Oxidation of iodine Organification Coupling
Other topics and Adverse effects