Lipid lowering drug that significantly reduces lipo protein-a levels is?
Fenofibrate
Gemfibrosil
Rosuvastatin
Nicotinic acid
Nicotinic acid is B3 vitamin which in higher doses reduce plasma lipids. When nicotinic acid is given, TGs and VLDL decrease rapidly, followed by a moderate fall in LDH-CH and total CH. It also reduces Lp(a) which is considered more atherogenic. It acts by inhibiting lipoprotein lipase produced from the endothelium From essentials of medical pharmacology K D Tripathi 7th edition page no 640
Cardiovascular system