Efalizumab is used in treatment of:
Acne vulgaris
Atopic dermatitis
Psoriasis
All of the above
Efalizumab (Raptiva) is an immunosuppressive recombinant humanized IgG1 kappa isotype monoclonal antibody that binds to the CD11a subunit of leukocyte function antigen-1. This binding affects the activation, adhesion, and migration of T lymphocytes. The recommended dosage in psoriasis is a single 0.7 mg/kg subcutaneous injection conditioning dose followed by weekly subcutaneous injections of 1 mg/kg not to exceed a maximum single dose of 200 mg. Ref: Katzung 11th edition Chapter 61.