Treatment of Acute Barbiturate poisoning includes which of the following?
Forced alkaline diuresis
Acidification of urine
Penicillamine administration
CaNa EDTA administration
Ans. is 'a' i.e., Forced Alkaline diuresis Acute barbiturate poisoning* It is mostly suicidal, sometimes accidental.* Manifestations are due to excessive CNS depression - patient is flabby and comatose with shallow and failing respiration, fall in BP and cardiovascular collapse, renal shut down, pulmonary complications and bullous eruption (barbiturate blisters).* Treatment:i) Gastric lavageii) Supportive measures (O2, assissed respiration, maintenance of BP).iii) Haemodialysisiv) Forced alkaline diuresis
C.N.S