Clostridium difficile infection occurs after
Prolonged antibiotic therapy
Pantoprazole increases the risk
Associated with use of rectal thermometer
Increased with propoion of hospital stay
Clostridium difficile causes acute colitis with bloody diarrhea and pseudomembranous colitis. A common cause of nosocomial diarrhea. The disease follows the use of broad-spectrum antibiotics to which it is resistant. Exotoxin A and B involved in the pathogenesis. An oppounistic organism that causes disease only when the normal mechanism is altered. Reference: Textbook of Microbiology; Anathanarayan and paniker's; 10th edition; Page no: 270
Bacteriology