Ballooning degeneration of hepatocytes is characteristically seen in:
Acute hepatitis
Chronic hepatitis
Cirrhosis
All of the above
With acute hepatitis hepatocyte injury takes the form of diffuse swelling ("ballooning degeneration"), so the cytoplasm looks empty and contains only scattered eosinophilic remnants of cytoplasmic organelles. Ref: Robbins 8th edition Chapter 18.