Which one of the following medications is most likely to be responsible for this appearance?
Clarithromycin
Dexamethasone
Doxorubicin
Efavirenz
Answer C. DoxorubicinSeveral chemotherapeutic drugs (including doxorubin and cyclophosphamide) cause dyspigmentation. Other groups of drugs that cause this problem include antimalarials, amiodarone, heavy metals (but not iron), tetracyclines, and antipsychotics.
Drugs