Splenic macrophages in Gaucher's disease differ from those in ceroid histiocytosis by staining
Lipids
Phospholipids
Acid Fast Stain
Iron
In Gaucher's disease there is an accumulation of Gaucher cells that Contain glucocerebroside which is a lipid (glycolipid)
In ceroid histocytosis, there is an accumulation of lipofuscin (ceroid), a yellow-brown cytoplasmic pigment, in the histiocytes.