A 45 years male HIV-1 positive was staed on a cA regimen of Tenofovir-Emtricitabine-Eirenz. After 9 months, he developed Eirenz resistance which lead to failure of therapy. Which of following drug of the same class can be used in place of Eirenz?
Delavirdine
Etravirine
Nelfinavir
Nevirapine
Etravirine is Non-Nucleoside Reverse Transcriptase Inhibitor (NNI). Etravirine in combination with other anti-retrovirals is indicated for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in antiretroviral treatment-experienced adult patients Resistance to other NNIs does not confer resistance to Etravirine so it can be used in place of Eirenz . Nelfinavir is a protease inhibitor and not NNI Nevirapine, Delavirdine, and Eirenz are NNIs
viral infection