In a child of infantile spasm and visual defect, which drug is not used even though it is highly effective?
Lamotrigine
Topiramate
ACTH
Vigabatrin
Two types of drugs are used in infantile spasm:* ACTH (drug of choice)* Vigabatrin (drug of choice if infantile spasm with Tuberous sclerosis)Vigabatrin is a GABA transaminase inhibitor. Major side-effect is visual field defect. It is indicated in Refractory focal seizures with impaired awareness.So, because of this side-effect it can't be used if the child already has visual defect.
Epilepsy