Hepatitis B infection persists in 3% asymptomatic individuals. Why is there an increased risk of developing liver cancer in these patients?
Inability to induce inflammation to remove organism
Increased liver transaminases
Recurrent episodes of inflammation
Integration of viral DNA to host DNA
Hepatocellular carcinoma and HBV Hepatis B is am impoant risk factor for HCC HBV persists in 3% of asymptomatic patients. But at increased risk of developing Liver cancer because of Integration of viral DNA to host DNA- Inhibition of apoptosis -Hepato-cellular carcinoma =High rate of hepatocyte proliferation- Refers to high infectivity of the virus so basically higher chances of infection but not cancer. =Inability to induce inflammation to remove organism -Explains for carrier stage
Hepatitis