Relative to filgrastim (G-CSF), sargramostim (GM-CSF)
Has greater oral bioavailability
Is more likely to cause thrombocytopenia
Is more likely to elicit an allergic reaction
Stimulates production of a wider variety of hematopoietic stem cells
Stimulates production of a wider variety of hematopoietic stem cells GM-CSF has wider biologic activity than G-CSF; it stimulates early myeloid stem cells in addition to cells destined become neutrophils.