Staph. aureus causes vomiting in 16-18 hours. The mechanism of action is
Stimulation of cy AMP
Vagal stimulation
Stimulation of cy GMP
Acts through ganglioside GM receptor
"The mechanism by which the staphylococcus aureus causes vomiting is uncertain but may involve direct neural stimulation of the autonomic nervous system rather than a local effect on G.I.T mucosa".