Jarisch Herxheimer reaction is commonly seen in-
Early syphilis
Late congenital syphilis
Latent syphilis
Syphilis of cardiovascular system
Jarisch herxheimer reaction acute self limiting febrile reaction that follow antibiotic therapy for syphilis develops after few hrs after initiation of treatment avg-6-7 hrs common in : early syphilis, secondary syphilis subsides in 12-48hrs clinical features: flu like symptoms, myalgia, ahralgias, headache,fever and hypotension lab: elevated neutrophils, and raised esr treatment: rest, asprin prevention : prednisone exercises 5mg aid 2 days prior to Rex, chlorphenaramine maleate prior to penicillin injection iadvl textbook of dermatology page 1836
Bacterial infections