Antidote for opioid poisoning;
Naloxone
Pethidine
Flumazenil
Physostigmine
Naloxone is an opioid antagonist given intravenously. It blocks mu, kappa and delta receptors. It is the DOC for opioid toxicity. is given parenterally (ineffective orally) and is a very sho acting drug. Pethidine (Meperidine)- fully agonist at opiod receptors Flumazenil-Flumazenil is specific antidote for benzodiazepines. Physostigmine - it is a lipid soluble anticholinesterase. It is the specific antidote for poisoning with belladonna.
FMGE 2019