Administration of which of the following drug requires therapeutic drug monitoring?
Lithium
Haloperidol
Diazepam
Acetazolamide
Therapeutic drug monitoring is adjustment of dose of the drug according to its plasma concentration. It is required for A Aminoglycosides (e.g. gentamicin) Drug Digitalis Possessing Phenytoin (anti-epileptics) Low Lithium Therapeutic Tricyclic antidepressants Index Immunomodulators (e.g. cyclosporine) Range of 0.8-1.2 mEq/L is ored for treatment of acute manic or hypomanic patients. 0.6-1.0 mEq/l is considered adequate and safer for long term prophylaxis.
Pharmacodynamics