Which of the following statements about terbinafine is FALSE?
Its activity is restricted to dermatophytes
It is effective in onychomycosis
It is not effective in cryptococcal meningitis
It is kunlikely to produce anti-androgenic side effects
(Ref: KDT 6/e p765) Terbinafine is a CIDAL drug against dermatophytes. It can be administered orally or can be applied topically. It acts by inhibiting the enzyme squalene epoxidase resulting in accumulation of toxic squalene.
Other topics and Adverse effects