In Cicatricial pemphigoid, which antigen is bound by IgG on the epidermal side of the salt split skin technique?
XVII collagen
Epiligrin
Laminin 5
BP antigen 1 & 2
Majority cases of mucous membrane pemphigoid or cicatricial pemphigoid demonstrate IgG directed against antigens on the epidermal side of the salt-split skin, which have been identified as BP 180 or XVII collagen. The antigen present on the dermal side is epiligrin (laminin 5).