All the following are biotin independent carboxylation reactions, EXCEPT
Addition of CO2 to from C6 in purine ring
Conversion of pyruvate to malate by malic enzyme
Acetyl CoA carboxylase
Carbamoyl phosphate synthetase
The  conversion of  pyruvate to  oxaloacetate by  biotin  dependent  pyruvate  carboxylase is essential for the synthesis of glucose from  many non-carbohydrate sources.