Which of the following type of aneurysm is associated with adult polycystic kidney disease?
Berry aneurysms in Circle of Willis
Saccular aneurysms of aoa
Fusiform aneurysms of aoa
Luetic aneurysms
Patients with ADPKD have a 2-4 fold increased risk subarachnoid or cerebral hemorrhage from ruptured berry aneurysm in the circle of Willis. Saccular aneurysms of the anterior cerebral circulation may be detected in up to 10% of asymptomatic patients on magnetic resonance angiography (MRA) screening. Patients at risk for hemorrhage are: Age more than 50 Family history of intracranial hemorrhage Aneurysms more than 10mm Uncontrolled hypeension Other extrarenal manifestations of ADPKD are: Mitral valve prolapse and aoic regurgitation Hepatic cysts Colonic diveicula Abdominal wall and inguinal hernias Ref: Harrison's Principles of Internal Medicine 18e chapter 284.