Which of the following is not a myeloproliferative neoplasm?
Polycythemia vera
Juvenile myelomonocytic leukemia
Chronic myeloid leukemia
Essential thrombocythemia
Juvenile myelomonocytic leukemia is not included in the category of MPNs (myeloproliferative neoplasms) in WHO classification Examples of myeloproliferative neoplasms: Chronic myeloid leukemia Polycythemia vera Primary myelofibrosis Essential thrombocythemia Chronic eosinophilic leukemia Activating JAK2 mutations are seen in: Nearly all cases of polycythemia vera Approx. 50% of cases of primary myelofibrosis and essential thrombocythemia BCR-ABL1 translocation seen in CML
Myeloproliferative Disorders