Amyl nitrate inhalation test is used to detect
Carcinoma esophagus
Achalasia cardia
Oesophageal diveiculum
Transeoesophageal fistula
Amyl nitrate inhalation (useful adjunct to the radiographic examination)seems to distinguish patients with pseudoachalasia from those with idiopathic achalasia. *In pseudoachalasia patients with tumour infiltration of the distal oesophagus, the narrow lower oesophagal sphincter segment was unaffected by the smooth-muscle relaxant effect of amyl nitrite. *amyl nitrate caused a measurable increase of 2 mm or more in sphincter diameter in patients with idiopathic achalasia ( smooth-muscle relaxant effect of amyl nitrite).
G.I.T