Which of the following is the investigation of choice for invasive amebiasis?
ELISA
Microscopy
Indirect hemagglutination
Counterimmunoelectrophoresis
Among the options given in the question ELISA is the investigation of choice in invasive amoebiasis. It has a sensitivity and specificity of 100 and 60%. But PCR assay for DNA in stool samples is currently most sensitive and specific method for identifying E.histolytica infection. Ref: Harrisons Internal Medicine, 18th Edition, Chapter 209 ; Current Medical Diagnosis and Treatment 2012, Chapter 35