A parent noted an abdominal mass in it. the side of her 6 mth. old child. Which showed calcification near the left kidney. what will be the cause
Neuroblastoma
Leukemia
Renal cell carcinoma
Lymphoma
Neuroblastoma is the most common solid tumor of infancy and childhood* and 3/4 of pt present with an abdominal mass. Plain x-ray shows fine, stippled calcification in 50 percent of the cases. More about Neuroblastoma Neuroblastoma is a malignant tumor of neural crest origin*, arising from the sympathetic nervous tissue from the orbit to the pelvis. Age - It occurs chiefly in very young children median age is 2 years. It is the most common solid tumor of infancy and most common tumor in newborn. * MC intrabdominal tumor in children. M.C. site is----- Adrenal medulla* 90% of pts. have increased catecholamine * secretion which can be identified by increased urinary levels of metanephrine and vanillylmandelic acid. Clinical evidence of catecholamine excess is however rare. Excessive VIP secretion presents with Hypokalemic watery diarrhoea * syndrome. Hematogenous metastasis occurs very early. Orbital metastasis* may present with proptosis, periorbital ecchymosis. Ref : Bailey & Love 25/e p814
Endocrinology and breast