Regarding transmission of HIV to infant from infected HIV mother, which statement is/are true:a) Start zidovudine during labour.b) 25% chance of vertical transmissionc) Avoid breast feedingd) Vaccinate infant with OPV and MMRe) Cesarean section cause less transmission
abce
abcd
acde
abde
According to the latest edition of Williams Obs 23/e, p 1252
An HIV infected woman on no antiretroviral medication who presents in labour Management includes: Start zidovudine i/v
OR
Start zidovudine plus a single dose of nevirapine. If nevirapine is initiated, consider adding lamivudine for 7 days post partum to decrease nevirapine resistance.
Williams Obs 23/e, p 1251, Table 59-8, p 1252
So option a is correct

Elective cesarean is the best mode of delivery as chances of transmission of HIV are less (i.e. option e is correct)
Breastfeeding should be avoided except in those cases where mother cannot afford formula feeds. (option c is correct).
Vertical transmission to the neonates is about 14-25%Q. (i.e. option b is correct) Transmission of HIV–2 is less frequent (1-4%) than for HIV-1 (15-40%)

Vaccination of HIV Infected Infant (Nelson)

Live oral polio vaccine (OPV) and BCG vaccine should not be given (i.e. option d is incorrect).
Varicella and MMR are recommended for children in immune categories. 1 and 2, but neither varicella nor MMR vaccines should be given to severely immunocompromised children (immune category 3).