True about vitamin K is:
It is required for synthesis of factor VII
Long term use of antimicrobials can cause deficiency of vitamin K
It is a water soluble vitamin
DVT is associated with vitamin K deficiency
Ans. (B) Long term use of antimicrobials can cause deficiency of vitamin K(Ref: KDT 8/e p661)Vitamin K is involved in activation of factor II, VII, IX and X (not synthesis)It is a fat soluble vitamin like Vitamin A, D and E. Vitamin B and C are water soluble.Warfarin (an inhibitor of vitamin K) is used for treatment of DVT.Long term antimicrobial use can alter gut flora leading to deficiency of vitamin K.
Hematology