All the following statements are true regarding beta-lactams except
Imipenem should be given with cilastatin
Meropenem should be given with cilastatin
Aztreonam doesn't show cross resistance with cephalexin
Methicillin is given by parenteral route
Among carbapenems, Imipenem should always be given with cilastatin to prevent renal failure and convulsions. No need to give mero and doripenem with cilastatin.Cross-resistance is not seen with aztreonam among beta-lactams.Methicillin is inactivated by gastric acid so administered parenterally.Ref: Katzung 3rd ed; pg 781
Antibiotics