"Pinch" purpura is diagnostic of -
Systemic primary amyloidosis
Secondary systemic amyloidosis
Idiopathic thrombocytopenic purpura
Drug induced purpura
Pinch Purpura: A Cutaneous. Manifestation of Systemic. Amyloidosis Amyloid purpura is a condition marked by bleeding under the skin (purpura) in some individuals with amyloidosis. Its cause is unknown, but coagulation defects caused by amyloid are thought to contribute presentation: Amyloid purpura usually occurs above the nipple-line and is found in the webbing of the neck and in the face and eyelids Ref Harrison20th edition pg 1245
Autoimmune skin disorders