Ganciclovir is used in the treatment of
Adenovirus
Cytomegalovirus
EB virus
Arenavirus
Ans. is 'b' i.e., Cytomegalovirus Ganciclovir is an antiherpetic antiviral drug. It is active against all Herpetic viruses such as - H. simplex H. Zoster E.B. virus Cytomega lo virus However it is more active against CMV. Because: - Concentration of active inhibitor ganciclovir triphosphate is much higher inside CMV infected cells. Plasma t1/2 of ganciclovir is 2-4 hrs but that inside CMV is > 24 hrs. Because systemic toxicity of Ganciclovir is very high, its use is restricted to CMV infections in immunocompromised patient.