Regarding sulpha group of drugs all the below statements are true, except:
Sulfonamide may cause Kernicterus in newborn
Sulfonamides are used in Norcardia infections
Crystalluria can occur with sulfonamide
Sulfasalazine is absorbed well from GIT
Sulfasalazine is usaually absorbed from the small intestines. Only 10% of drug is absorbed remaining excreted unaltered in bowel. Hence, this drug acts locally in the intestine of patient with inflammatory bowel disease. Ref: Paul Beringer (2006), Chapter 90, "Antiinfectives", In the book, "Remington: The Science and Practice of Pharmacy", Lippincott Williams and Wilkins, USA, Page 1631 ; KD Tripathi, 5th Edition, Pages 186, 643 ; Katzung 9th Edition, Page 591