Which of the following is the necessary pre-operative investigation which has to be done in a patient with Down's syndrome posted for surgery?
CT Brain
Echocardiography
Ultrasound Abdomen
X-Ray cervical spine
Down's syndrome is associated with cardiac manifestations such as Endocardial cushion defect, ASD, VSD and Tetrology of fallot. So echocardiography is the necessary pre-operative investigation to be done before surgery in a patient with Downs' syndrome. Ref: Harrison's Principles of Internal Medicine, 16th Edition, Page 1382