Mitochondrial DNA (mt-DNA) is known for all except:
Maternal inheritance
Heteroplasmy
Leber hereditary optic neuropathy is the prototype
Nemaline myopathy results due to mutations in mt- DNA
Nemaline myopathy Autosomal recessive Heterogeneous condition and not a mitochondrial disease. Myopathy d/t 5 genes . All code for thin filament-associated proteins, suggesting disturbed assembly or interplay of these structures as a pivotal mechanism. Mutations of the nebulin (NEB) gene Severe neonatal and early childhood forms
Genetics