Best test for diagnosis of Carcinoid tumor:
24 hour urinary 5H.I.A.A
24 hour catecholamines
24 hour vaniylmandelic acid levels
24 hour metanephrine levels
Ans. (a) 24 hour urinary 5H.I.A.ARef: Harrison 19th ed. 1564-65* 5-HLAA is the major urinary metabolite of serotonin, a ubiquitous bioactive amine. Serotonin, and consequently 5-HLAA, are produced in excess by most carcinoid tumors, especially those producing the carcinoid syndrome of flushing, hepatomegaly, diarrhea, bronchospasm, and heart disease.
Miscellaneous (Endocrinology)