17-year-old girl with amenorrhea, atrophied breast, hypoplastic uterus:
Turner's syndrome
Gonadal dysgenesis
Androgen insensitivity syndrome
Klinefelter's syndrome
Here the patient is 17 years old and has amenorrhea (i.e. Primary Amenorrhea) with atrophied breast and hypoplastic uterus. Hypoplastic uterus can be seen in case of:
• In klienefelter syndrome – Gonada are testis and not ovaries. The patient externally resembles a male and not female. Uterus is also absent.
• In pure Gonadal dysgenesis. Uterus and cervix are present but infantile and there is some development of secondary sexual characteristics and a few episodes of bleeding (Leon speroff 8th/ed p1040)
• In Androgen Insensitivity Syndrome – uterus is absent but breast development is normal, so it is also ruled out.