With help of the drug shown below, serotonin is synthesized from which of the following precursor amino acid?
Tryptophan
Glycine
Threonine
Methionine
Tryptophan. Serotonin is synthesized from the essential amino acid tryptophan. The rate-limiting step is the conversion of the amino acid to 5-hydroxytrptophan by tryptophan hydroxylase. This is then conveed to serotonin by the aromatic L-amino acid decarboxylase which needs Pyridoxal Phosphate as a cofactor Ref : vasudevan 7th ed
All India exam