A 5–year old boy presents with pubic hair development. He is tall and has increased pigmentation of his genitalia and phallic enlargement. Blood pressure is 130/90 mm g. Measurement of which of the following diagnostic? hormones would be most likely to be diagnostic?
Increase 17 beta hydroxyl progesterone
Increase cortisol
Increase aldosterone
Increase 11 deoxycortisol
Presence of Precocious puberty in a male child and hypertension (BP of 130/80 in a 5-year-old child is considered hypertension) suggests a diagnosis of congenital adrenal Hyperplasia due to 11-β Hydroxylase deficiency.
levels and excretion of 11 deoxycortisol are increased.