When a diagnostic test is used in series mode then-
Sensitivity increases but the specificity decreases
Specificity increases bu the sensitivity decreases
Both sensitivity and specificity increases
Both sensitivity and specificity decreases
Ref:Parks 23rd edition pg 137 When used in series: Sensitivity decreases Specificity increases PPV increases NPV decreases When used in parallel : Sensitivity increases Specificity decreases PPV decreases NPV increases
Screening