The serum concentration of which of the following human IgG subclasses is maximum?
IgG1
IgG2
IgG3
IgG4
IgG is the major class of immunoglobulin present in the serum. The IgG molecule consists of two L chains and two H chains (H2L2). There are four subclasses of IgG: IgG1, IgG2, IgG3, and IgG4. Each subtype contains a distinct but related H chain and each differs somewhat regarding their biological activities. IgG1 represents 65% of the total IgG.IgG2- 23%, IgG3 -8% and IgG4 - 4%Reference: Jawetz, Melnick, & Adelberg's Medical Microbiology; 27th edition; Chapter 8; Immunology
Immunology