Infant with carnitine deficiency form hypoglycemia due to what reason?
Decreased glycosis
Decreased gluconeogenesis
Increased utilization of glucose
Reduced fatty acid oxidation and ketogenesis
Carnitine deficiency can occur paicularly in the newborn-- and especially in preterm infants--owing to inadequate biosynthesis or renal leakage. Losses can also occur in hemodialysis.This suggests a vitamin-like dietary requirement for carnitine in some individualsSymptoms of deficiency include hypoglycemia, which is a consequence of impaired fatty acid oxidation and lipid accumulation with muscular weakness.Treatment is by oral supplementation with carnitineReference: Harper biochemistry, 30th edition, page no 231
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