Which of the following zone of the liver lobule is more prone to ischemia?
Peripoal
Midzonal parenchyma
Centrilobular zone
All zones are affected equally
Centrilobular zone (zone 3) is zone with poor oxygenation , therefore is more prone to ischemia * Liver is divided histologically into lobules. * The center of the lobule is the central vein. * At the periphery of the lobule are poal triads. * Based on the oxygen supply , the liver can be divided into three zones. Zone 1 : Peripoal zone - encircles the poal tracts where the oxygenated blood from hepatic aeries enters. Zone 2 : Midzonal parencyma - is located in between. Zone 3 : Centrilobular Zone - is located around central veins, where oxygenation is poor.
Miscellaneous