The following is a generalized diagram of a typical eukaryotic gene , What is the most likely effect of a 2bp insertion in the middle of the intron?
Normal transcription, altered translation
Defective termination of transcription, normal translation
Normal transcription, defective mRNA splicing
Normal transcription, normal translation
Introns are non-coding region of gene which are processed out of primary transcript. Hence, any change in intron will not effect transcription or translation.