Role of carnitine in lipid metabolism ?
Catalyzation of the cyclization sequence
Essential for extracellular transfer of fatty acids
Essential for biosynthesis of fatty acids
Transfer of activated long chain FFA into mitochondria
Ans. is 'd' i.e., Transfer of activated long chain FFA into mitochondria Activated long chain fatty acid (acyl CoA) cannot penetrate inner mitochondria! membrane. Acyl group of acyl CoA is transferred to carnitine, resulting in formation of acylcarnitine. Acylcarnitine is then transpoed across the inner mitochondria! membrane into the mitochondria! matrix by translocase. Once inside the mitochondrion, acyl group of acylcarnitine is transferred back to CoA, resulting in formation of acyl-CoA which undergoes 13-oxidation.