The normal cellular counterpas of oncogenes are impoant for the following functions, except ?
Promotion of cell cycle progression
Inhibition of apoptosis
Promotion of DNA repair
Promotion of nuclear transcription
o Normal cellular counterpa of oncogene is protooncogene.o The functions of protooncogene is to code forGrowth factorsGrowth factor receptorsProteins involved in signal transductionNeuclear regulatory proteins (transcription factors)Cyclins/CDKso All these lead to cell proliferation and progression of cell cycle.o When any of these protooncogenes becomes oncogene by mutation / overexpression, there is uncontrolled proliferation of cell and development of cancer.This proliferation is autonomous, i.e. without physiological stimulus.