The site of action of vasopressin antagonist in kidney
Medullary Collecting duct
Coical collecting duct
Proximal convoluted tubule
Distal convoluted tubule
V2 receptors are located on medullary collecting ducts. drugs acting on V2 receptor antagonists are vaptans like convivaptan and tolvaptan Ref: Goodman Gillman 12th ed pg 707
Kidney