Hirschsprung colon is due to
Muscle atrophy in muscularis mucosa
Loss of intrinsic enteric plexuses
Loss of extrinsic nerve supply
None
Hirschsprung's Disease (Congenital Megacolon) The term 'megacolon' is used for any form of marked dilatation of the entire colon or its segment may occur as a congenital or acquired disorder. Congenital form: congenital absence of ganglion cells in the bowel wall (enteric neurons) is called Hirschsprung's disease. As a result, the aganglionic segment remains contracted. Gross: shows 2 segments, a distal narrow segment that is aganglionic and a dilated proximal segment that contains normal number of ganglion cells Microscopy: distal narrow segment shows total absence of all the three plexus( Auerbach's, Here's, and Meissner's plexus) TEXTBOOK OF PATHOLOGY 6TH EDITION HARSH MOHAN PAGE NO:580 IMAGE REFERENCE:
G.I.T