Sirolimus is more likely than cyclosporine to cause:
Hypeension
Osteoporosis
Renal insufficiency
Thrombocytopenia
(Ref: KDT 6/e p840) Cyclosporine and tacrolimus cause nephrotoxicity as an adverse effect. Sirolimus (rapamycin) results in bone marrow suppression and thus may cause anemia, thrombocytopenia and leukopenia.
Other topics and Adverse effects