Pyruvate Dehydrogenase complex has all enzyme components EXCEPT:
Pyruvate Dehydrogenase
Dihydrolipoyl Transacetylase
Dihydrolipoyl Dehydrogenase
Pyruvate Decarboxylase
PDH complex has 3 enzyme components: 1. E1: Pyruvate Dehydrogenase 2. E2: Dihydrolipoyl Transacetylase 3. E3: Dihydrolipoyl Dehydrogenase REGULATION OF PDH End Product Inhibition Covalent Modification Acetyl CoA (in fasting) NADH Active in dephosphorylated state Done by Insulin
Link reaction