All of the following are the disadvantages of anticancer drugs, Except
Low selectivity to cancer cells
Depression of bone marrow
Depression of angiogenesis
Depression of immune system
Depression of angiogenesis is used to treat ceain cancers like renal and lung carcinoma by inhibition of VEGF -eg: Sunitinib.Ref: Sharma and Sharma 2nd e / pg 852.
Chemotherapy