Withdrawal bleeding following administration of progestogen in a case of secondary amenorrhea indicates all except
Absence of pregnancy
Production of endogenous estrogen
Endometrium is responsive to estrogen
Defect in pituitary gonadal axis
Ans. is d, i.e. Defect in pituitary gonadal axisRef: Dutta Gynae 6th/ed, p467; Leon Speroff 7th/ed, p404-409Withdrawal bleeding following administration of progesterone suggests:* The uterus is sufficiently primed with estrogen, i.e. production of endogenous estrogen is normal which means. Ovaries and hypothalamic pituitary axis are functioning normally.* The outflow tract (uterus) is normal and endometrium is responsive to estrogen.* There is a defect in production of progesterone (so pregnancy ruled out).
Disorders in Menstruation