Which of the following statement about Bradykinin is true?
Causes pain
Causes bronchodilation
Causes vasoconstriction
Decreases vascular permeability
Bradykinin increases vascular permeability, causes contraction of smooth muscles (bronchoconstriction), dilatation of blood vessels and pain. Ref: Urinary Tract By Karl-Erik Andersson, Page 413; Peptidergic G Protein-coupled Receptors: From Basic Research to Clinical Applications By Pierangelo Geppetti, Page 100; The New Angiotherapy By Tai-Ping D. Fan, Elise C. Kohn, Page 94; Robbin's Illustrated Pathology, 7th Edition, Pages 65, 74, 75