Febrile response in CNS is mediated by all except
Bacterial toxin
IL-l
IL-6
Interferon
Fever is produced in response to substances called pyrogens that act by stimulating prostaglandin synthesis in the vascular and perivascular cells of hypothalamus.
They can be classified as:

Exogenous pyrogens - Endotoxin of gram ‘-’ bacteria, superantigens (gram ‘+’ bacteria).
Endogenous pyrogens - IL-1, TNF-alpha, Ciliary neurotropic factor and IFN-alpha.

PGE 2 is the most important chemical responsible for elevation of hypothalamic set point in the body.
So, NSAIDs reduce fever by inhibiting cyclooxygenase and reducing prostaglandin concentration.