End diastolic volume increases in:
Decrease in total blood volume
Increase in intrapericardial pressure
Increase in negative intrathoracic pressure
Decrease in ventricular compliance
Ans. c. Increase in negative intrathoracic pressureFactors Affecting End Diastolic VolumeEnd diastolic volume increases in conditions associated with increase in negative intrathoracic pressure.Factors Decreasing EDVIncreased intra-pericardial pressuredeg (as aresult of infection of pressure from a tumor):Limits the extent to which ventricle can fillDecrease in ventricular compliancedeg:Increase in ventricular stiffness produced by MI, infiltrative disease.Standing decreases venous returndegFactors Increasing EDVIncreased total blood volume increases venous returndeg:Constriction of vein reduces the size of venous reservoirIncreased negative intrathoracic pressuredeg:Increases the pressure gradient along which blood flows to theMuscle activitydeg: Increases venous return as a result of pumping action