Advantage of newer liposomal preparation of amphotericin B
Similar in efficacy and antifungal spectrum as conventional preparations
Fewer chances of nephrotoxicity
Lesser uptake in the tissues like the kidney
All of the above
Newer liposomal preparations of amphotericin B have the following features:

Fewer chances of nephrotoxicity and infusion-related reactions
Lesser uptake in the tissues like kidney
More expensive
Similar in efficacy and antifungal spectrum as conventional preparations