Which of following anti-gout drugs act by inhibiting the enzyme xanthine oxidase?
Probenecid
Rasburicase
Allopurinol
Sulfinpyrazone
DRUGS USED IN CHRONIC GOUT Group Mechanism Drugs Uric acid synthesis inhibitors Xanthine oxidase inhibitors Allopurinol, Febuxostat Uricosuric agents URAT-1 transpoer inhibitors Probenecid, Sulfinpyrazone, Benzbromarone, Lesinurad Recombinant uricase Cause oxidation of urate to allantoin Rasburicase, Pegloticase
NSAIDs, Gout and Rheumatoid Ahritis