Regarding severe combined immunodeficiency, which is true?
Adenosine deaminase deficiency
Decreased circulating lymphocytes
NADPH oxidase deficiency
C1 esterase deficiency
Severe combined immunodeficiency Constellation of genetically distinct syndromes Defects in both humoral & cell-mediated immune response MC form - XLR - so more in males; mutation in g chain subunit of cytokine receptors Remaining - AR; deficiency of enzyme ADA
General pathology