Which of the following carcinoma causes osteosclerotic bone metastasis commonly?
Kidney
Thyroid
Lung
Prostate
Metastases are most commonly seen in the pelvis, ribs, veebral bodies, and proximal limbs. These lesions typically have a lytic appearance on plain radiographs, although breast and prostate metastases can be sclerotic or mixed with lytic and sclerotic features. Must know: Overall, metastases are the most common tumor of bones. Adults: Approximately 75% of metastases to the bone are derived from prostate, breast, kidney, and lung carcinomas. Children: Neuroblastoma, Wilms tumor, osteosarcoma, and Ewing sarcoma. Kidney and thyroid neoplasms are known for producing a solitary metastasis. Metastases to hand and foot bones are uncommon and, if present, the source is usually a lung, colon, or renal neoplasm. Ref: Srinivasan R.C., Tolhurst S., Vanderhave K.L. (2010). Chapter 40. Ohopedic Surgery. In G.M. Dohey (Ed), CURRENT Diagnosis & Treatment: Surgery, 13e.