Drug of choice for precocious puberty:
Cyproterone acetate
Danazol
Medroxyprogesterone
GnRH agonists
d. GnRH agonists(Ref: Nelson's 20/e p 2658)Nelson latest ed says: "Long-acting formulations of GnRH agonists, which maintain fairly constant serum concentrations of the drug for weeks or months, constitute the preparations of choice for treatment of central precocious puberty."
Endocrinology