Combination of amoxycillin with clavulanic acid is active against all of the following organisms except
MRSA
Penicillinase producing Staph, aureus
Penicillinase producing N. gonorrhoea
Beta lactamase producing E. coli
Ans. (A) MRSA(Ref: GG 1479)Methicillin resistance occurs due to altered penicillin binding proteins, therefore cannot be reversed by b-lactamase inhibitor like clavulanic acid
Chemotherapy: General Principles