Which of the following is the most impoant factor in determining the development of diabetic nephropathy?
Duration of the disease
Hypeension
Pre-existing renal disease
Control with treatment
Most impoant risk factor for development of diabetic nephropathy is the duration of diabetes. 30% of patients with type 1 diabetes develop microalbuminuria after 20 years of onset of diabetes. 5 -25% of patients develop clinically significant renal failure at the time of diagnosis and 30% develop ESRD at 20years duration.