Skin depigmentation, bilateral uveitis and tinnitus are features of –
Vogt Koyanagi harada syndrome
Waardenburg Syndrome
Alport Syndrome
Werner's Syndrome
Vogt Koyanagi - Harada (VKH) syndrome

It is an idiopathic multisystem disorder which includes cutaneous, neurological and ocular lesions.
The disease is comparatively more common in Japanese who are usually positive for HLA-DR4 and DW15.

Clinical features


Cutaneous lesions include: alopecia, poliosis and vitiligo.


Neurological lesions are in the form of meningism, encephalopathy, tinnitus, vertigo and deafness.


Ocular features are bilateral chronic granulomatous anterior uveitis, posterior uveitis and exudative retinal detachment.