all the following statements about hybridoma technology are true except :
specific antibody producing cells are integrated with myeloma cell
myeloma cells in salvage pathway grows well in HAT medium
aminopterin, a folate antagonist inhibits denovo pathway
HGP ase and thymidylate sytnthtase are required for salvage pathway
myeloma cells lack HGPase enzyme hence they cannot grow well in HAT medium APPLICATION OF HYBRIDOMA TECHNOLOGY Serological, * Identification of ABO blood group Diagnosis: * Detection of pregnancy by assaying of hormones with monoclonal. * Separation of one substance from a mixture of very similar molecules. Immunopurification: * Purification of individual interferon using monoclonal. * Inactivation of T-Iymphocytes responsible for rejection of organ transplants. Therapy: * Removal of tumor cell from bone marrow. * Treatment of acute renal failure. * Treatment malignant leukemic cells, B cell lymphomas, and a variety of allograft rejections after transplantation. ref : ananthanaryana 9th ed
All India exam