All of the following are included in the criteria for diagnosis of SLE, except:
Oral ulcers
Psychosis
Discoid rash
Leucocytosis
Criteria (2012) for diagnosis of SLE Clinical manifestations Skin Acute, subacute cutaneous LE (photosensitive, malar, maculopapular, bullous) Chronic cutaneous LE (discoid lupus, panniculitis, lichen planus-like, hyperophic verrucous, chillblains) Oral or nasal ulcers Nonscarring Alopecia Synovitis involving >=2 joints Serositis (pleurisy, pericarditis) Renal Protein/Cr ratio >=0.5, RBC casts, Biopsy (lupus nephritis) Neurologic Seizures, psychosis, mononeuritis, myelitis, peripheral or cranial neuropathies, acute confusional state Hemolytic anemia Leukopenia (<4000/mL) or Lymphopenia (<1000/mL) Thrombocytopenia (<100,000/mL) Immunological manifestations ANA > reference negative value Anti-dsDNA antibody >reference, if by ELISA 2x reference Anti-Sm antibody Antiphospholipid (any of lupus anticoagulant, anti-cardiolipin, anti-b glycoprotein I) Low serum complement (C3, C4 or CH50) Positive direct Coombs test in absence of hemolytic anemia
Auto Immune Disorders Introduction