Niacin is dangerous in diabetes mellitus because:
It causes insulin resistance
It causes sudden hypoglycemia
It decreases glucagon secretion
It decreases effect of other OHA
Ans. a. It causes insulin resistanceRef: Goodman Gilman 12th e/P 900Niacin causes insulin resistance and hence causes severe hyperglycemia in patients of diabetes mellitus.Hence it should be avoided in patients of diabetes mellitus.
Endocrinology