Which of the following anti - hypertensives was once used as an antipsychotic?
Atenolol
Propranolol
Clonidine
Reserpine
Reserpine is an antihypertensive drug which was used as an antipsychotic. Antipsychotic effect of reserpine is due to depletion of 5 - HT or catecholamine or both.
Clonidine is also an antihypertensive. Its uses in psychiatry are - ADHD, opioid withdrawal, Tourette's syndrome and suppression of agitation in PTSD.