Ivabradine is used for management of ?
Stable angina
Pre renal azotemia
Alzheimers disease
Anti smoking agent
Ans. is 'a' i.e., Stable angina(Ref: KDT Vh/e p. 554; Cardiac drug development guide by Micheal Pugsley p. 381)IvabradineIt is an investigational inhibitor ofsino-atrial node.It is a relatively selective If(funny current) Sodium channel blocker of early pa of slow diastolic depolarization (phase 4) that reduces hea rate by inhibiting the hyperpolarization-activated sodium channel in SA node.Hea rate is a major determinant of angina in coronary disease.Therefore, lowering the hea rate is an impoant therapeutic approach in the treatment of stable angina.