In a case of vesicular mole, all of following are high risk factors for the development of choriocarcinoma, EXCEPT:
Serum HCG levels>1,00,000 mIu/ml
Uterus size larger than 16 week
Features of thyrotoxicosis
Presence of bilateral theca lutein cysts of ovary
High risk factors which indicates the development of choriocarcinoma at the time of diagnosis of a hydatidiform mole are: Maternal age more than 40 years Excessive uterine enlargement Serum hCG levels more than 100,000mIU/ml Theca lutein cysts greater than 6 cm in diameter Toxemia, hypehyroidism and coagulopathy Trophoblastic embolization Previously treated choriocarcinoma Ref: A Practical Approach to Gynecologic Oncology By Basu page 142.