18 year old female presents with an ovarian mass, her serum LDH & placental alkaline phosphate are found to be elevated. What is the treatment of choice in this condition?
B/L oophorectomy & post op radiotherapy
Oophorectomy on the involved side
Only chemotherapy
Hysterectomy with bilateral salpingopherectomy
The given scenario suggests the diagnosis of Dysgerminoma Most common germ cell malignancy High risk: dysgenetic gonads, testicular feminisation syndrome Tumour markers: LDH, PLAP, (hcg may be raised in some but AFP is normal) In Dysgerminoma, conservative surgery (U/L Salphingo-Oophorectomy) recommended as most patient are Young girls Post operative Chemotherapy gives 90% success NOTE: bilateral salpingo-oophorectomy is not done here in order to conserve ovarian function and feility unless mentioned that the presentation is bilateral.
Ovarian Tumors and Vulvar cancer