Which of the following is true regarding tuberculous lymphadenitis: March 2005
History of contact with TB patient may be present
Commonly seen in the young and children
Mostly in the cervical region
All of the above
Ans. D: All of the above Tuberculous lymphadenitis/ tuberculous adenitis is a chronic specific granulomatous inflammation with caseation necrosis of the lymph node. The characteristic morphological element is the tuberculous granuloma (caseating tubercule): giant multinucleated cells (Langhans cells), surrounded by epithelioid cells aggregates, T cell lymphocytes and few fibroblasts. Granulomatous tubercules evolve to central caseous necrosis and tend to become confluent, replacing the lymphoid tissue.