Massive transfusion in healthy adult male can cause hemorrhage due to: March 2011
Increased tPA
Dilutional thrombocytopenia
Vitamin K deficiency
Decreased fibrinogen
Ans. B: Dilutional thrombocytopenia Massive blood transfusion causes dilutional coagulopathies especially dilutional thrombocytopenia (stored blood has no platelets and concentration of other clotting factors is also very less)