ELISA is performed on a population with low prevalence. What would be the result of performing double screening ELISA tests -
Increased sensitivity and positive predictiv value
Increased sensitivity and negative predictive value
Increased specificity and positive predictive value
Increased specificity and negative predictive value
The specificity of ELISA can be increased by carrying out ELISA in a row (series) using different HIV markers.
When screening test is used in a series mode : -


↑ Specificity
↑ PPV
↓ Sensitivity