Mechanism of action of zileuton:
Inhibit prostaglandin synthesis
Inhibit COX
Inhibit LOX
Inhibit mast cells
Ans. C. Inhibit LOXArachidonic acid is acted upon by two enzyme-COX and LOX. Lox converts it into leukotrienes and Cox into prostaglandin. Zileuton is the inhibitor of LOX enzyme and it is used in treatment of asthma.
Prostaglandins