Losaan is similar to enalapril in all of the following features except:
Anti-hypeensive efficacy
Potential to reverse left ventricular hyperophy
Lack of effect on carbohydrate tolerance
Potential to induce cough in susceptible individuals
Losaan belongs to the class of ARB'sEnalapril belongs to the class of ACEI ARB's differs from ACE inhibitors in: They do not interfere with degradation of bradykinin: no rise in level of bradykinin, substance P occurs. ARB does not produce cough. With Losaan no significant effect on plasma lipid profile, carbohydrate tolerance or insulin sensitivity has been noted. A mild probenecid- like uricosuric action is produced.
CHF, Angina Pectoris and Myocardial Infarction