Primary metabolic bone disorder in scurvy is ?
Decreased mineralization
Decreased osteoid matrix formation
Increased bone resorption
Decreased bone mass with normal mineralization and osteoid formation
Ans. is 'b' i.e., Decreased osteoid matrixo Collagen is a component of osteoid (protein matrix).o Collagen synthesis is deficient in scurvy; therefore, osteoid formation is defective.o On the other hand, in rickets osteoid formation is normal, but mineralization (Calcification) of osteoid is defective.