Transplantation of liver is contraindicated in
Metastasis of liver
Acute fulminant liver disease
Viral hepatitis
Renal failure
Contraindications to Liver Transplantation Absolute Relative Uncontrolled extrahepatobiliary infection Active, untreated sepsis Incorrect able, life-limiting congenital anomalies Active substance or alcohol abuse Advanced cardiopulmonary disease Extrahepatobiliary malignany (not including nonmelanoma skin cancer) Metastatic malignancy to the liver Cholangiocarcinoma AIDS Life-threatening systemic diseases Age >70 years Prior extensive hepatobiliary surgery Poal vein thrombosis Renal failure not attributable to liver disease Previous extrahepatic malignancy( not including nonmelanoma akin cancer) Severe Obesity Severe malnutrition/wasting Medical noncompliance HIV seropositivity with failure to control HIV viraemis or CD4 <100/uL Intrahepatic sepsis Severe hypoxemia secondary to right - to-left intrapulmonary shunts (Po2<50mmHg) Severe pulmonary hypeension(mean pulmonary aery pressure >35 mmHg) Uncontrolled psychiatric disorder Ref: Sabiston 20th edition Pgno : 637-638
G.I.T