Which of the following is FALSE about insulin action?
Glycogen synthesis
Glycolysis
Lipognesis
Ketogenesis
Insulin inhibits lipolysis by inhibiting hormone sensitive lipase. Thus insulin prevents ketogenesis. Insulin stimulates glycolysis by activating PFK-1 Insulin activates glycogenesis by activating glycogen synthase. Also it stimulates fatty acid synthesis by activating acetyl Co A carboxylase. Insulin also--by its ability to depress the level of intracellular cAMP--inhibits lipolysis in adipose tissue reducing the concentration of plasma-free fatty acids and, therefore, long-chain acyl-CoA, which are inhibitors of lipogenesis. Ref: Botham K.M., Mayes P.A. (2011). Chapter 23. Biosynthesis of Fatty Acids & Eicosanoids. In D.A. Bender, K.M. Botham, P.A. Weil, P.J. Kennelly, R.K. Murray, V.W. Rodwell (Eds), Harper's Illustrated Biochemistry, 29e