25/M presented with jaundice, clay coloured stool and pruritus. Bilirubin was 7gm%, Direct Bilirubin 5gm%, ALP 500 IU/L. Biopsy from biliary tract revealed the following. What is your diagnosis?
PSC
SBC
PBC
Bile duct stones
Ans. (a) PSC* Clinical feature of jaundice, clay coloured stool and pruritus is suggestive of obstructive jaundice. Biopsy showing fibrotic obliteration of bile ducts ("onionskin" fibrosis) seen in primary biliary cirrhosis.
Liver & Biliary Tract