Aggrevation of symptoms of angina in a patient when given nitrates is seen in
Aoic regurgitation
Mitral regurgitation
Single left coronary aery stenosis
Idiopathic hyperophic subaoic stenosis
Ref Harrison 19 th ed pg 1568 Idiopathic hyperophic cardiomyopathy ( HOCM) is a dynamic outflow obstruction which is increased by any mechanism decreasing the preload . Nitrates decrease the preload,the volume of blood in LV and thereby increase the dynamic obstruction and symptom of angina
C.V.S