Which of the following statements about Cushing's disease is true?
Serum adrenocoicotropin (ACTH) levels usually are low
Pituitary microadenoma usually is present
There is a high incidence of nonendocrine tumors
Nonsuppression of coisol production by the high-dose dexamethasone suppression test is a characteristic finding
Cushing's syndrome is due to increased adrenal coisol production, regardless of aetiology.Cushing's disease usually is caused by a pituitary microadenoma producing high adrenocoicotropin (ACTH) levels.In most patients, coisol levels would be suppressed as a result of the high-dose dexamethasone suppression test.Transsphenoidal microsurgical removal of the microadenoma is the treatment of choice in most centres.
All India exam