Clinical manifestations of acute glomerulonephritis include which of the following?
Chills and flank pain
Oliguria and generalized edema
Hematuria and proteinuria
Dysuria and hypotension
Hematuria and proteinuria indicate acute glomerulonephritis.
These finding result from increased permeability of the glomerular membrane due to the antigen-antibody reaction. 
Generalized edema is seen most often in nephrosis.