Most common cause of ectopic ACTH production -
Renal cell carcinoma
Hepatocellular carcinoma
Small cell carcinoma lung
Pheochromacytoma
Ectopic ACTH can be secreted from original cancer tissues or metastatic lesions of SCLC. ... We repo a case of SCLC with Cushing syndrome due to EAS from the original tumor tissue in a 69-year-old male presenting with severe hypokalemia, metabolic alkalosis, and hypeension without any respiratory symptoms Ref Harrison 20th edition pg 597
Oncology