Which of the following is used to maintain abstinence in alcohol dependence
Naltrexone
Clonidine
Disulfiram
Naloxone
Naltrexone (oral opioid receptor antagonist) probably interferes with alcohol-induced reinforcement by blocking opioid receptors., helping in maintaining alcohol abstinence. Ref: Sho textbook of Psychiatry by Niraj Ahuja 7th editon, page 42. Disulfiram also helps in alcohol abstinence but through its unpleasant reactions to alcohol intake.
Substance abuse