Which of the following drugs is most likely to precipitate angina?
Amlodipine
Nifedipine
Diltiazem
Verapamil
Vasodilators and peripherally acting CCBs (Dihydropyridines) can cause tachycardia and thus may precipitate acute attack of angina. Risk of tachycardia is more with sho acting drugs like nifedipine than with long acting agents like amlodipine. Diltiazem & Verapamil --> decreases HR and also cause vasodilation.
CHF, Angina Pectoris and Myocardial Infarction