The difference between iron sorbitol-citric acid and iron dextran is that the former
Cannot be injected i.v.
Is not bound to transferrin in plasma
Is not excreted in urine
Produces fewer side effects
(Ref: KDT 6/e p586) Iron sorbitol citrate should not be used i.v. because it may rapidly saturate the transferrin receptors and can result in high concentrations of free iron.
Other topics and Adverse effects