Which of the following beta blocker has additional vasodilator action?
Atenolol
Metoprolol
Propranolol
Carvedilol
Carvedilol has additional vasodilatory action due to its alpha blocking propey. These are called third generation beta blockers. Third-Generation Beta-Blockers - a blockade (labetalol, carvedilol), - b2 agonism (celiprolol, caeolol, bopindolol), - Release of NO (nebivolol, nipradilol), - Opening of K+ channels (tilisolol) - Inhibition of Ca2+ channels (carvedilol, bevantolol, betaxolol).
Sympathetic System