Which of the following is the mechanism of action of new drug Rhopressa for glaucoma treatment
Increased uveoscleral outflow
Increased trabecular meshwork outflow
Increased aqueous production
Decreased aqueous production
Increased trabecular meshwork outflow is the mechanism of action of new drug Rhopressa (rho- kinase inhibitors) New Drugs in Glaucoma Anecorvate - Angiostatic steroid. Ethacrynic acid latrunculins - cellular cytoskeletal modulators. Alter TM shape. Olmesean, lomerizine, nivaldipine - improves vascular perfusion. Neurotropic- FGF ,increase ganglion cell life. Memantine : NMDA antagonist. Rho kinase inhibitors increase TM outflow.
Glaucoma