Asbestosis of the lung is associated with all of the following except-
Mesothelioma
Progression of lesion even after stopping exposure to asbestos
Nodular lesions involving upper lobe
Asbestos bodies in sputum
Ans. is 'c' i.e., Nodular lesions involving upper lobes Pulmonary changes of asbestos exposure o Pleural plaques are the most common manifestation of asbestos exposure. They are well-circumscribed plaques of dens collegen, often containing calcium. They develop most frequently on the anterior and posterolateral aspects of parietal pleura and over dome of diaphragm. o There is diffuse interstitial fibrosis mainly involving lower lung fields. Involved pa contains asteroid bodies --> golden brown, fusiform or beaded rods with a translucent center and consist of asbestos fibers coated with an iron-containing proteinaceous material. o Other inorganic paiculates may become coated with similar iron protein complexes and are called ferruginous bodies. Option "B" o Asbestosis is a pneumoconiosis caused by exposure to asbestos (a commercial name given to ceain types of fibrous material). o The disease occurs at least 5 to 10 yrs. after exposure. o In many cases disease presents itself years after the exposure has ceased.