Which of the following acquired conditions is low risk for thrombosis?
Heparin induced thrombocytopenia
Oral contraceptive use
Antiphospholipid antibody syndrome
Myocardial infarction
Ans. is 'b' i.e., Oral contraceptive use Hypercoagulable statesPrimary (Genetic)CommonFactor V mutation (Arg to Glu substitution in amino acid residue 506 leading to resistance to activatedprotein C; factor V leiden)Prothrombin mutation (G2021QA noncording sequence variant leading to increased prothrombin leveis)Increased levels of factors VIII, IX, XI or fibrinogen (genetics unknown)RareAntithrombin III deficiencyProtein C deficiencyProtein S deficiencyVary RareFibrinolysis defectsHomozygus homocystinuria (deficiency of cystathione b-synthetase)Secondary (Acquired)High risk for thrombosisProlonged bed rest or immobilizationMyocardial infarctionAtrial fibrilationTissue injury (surgery, fracture, bum)CancerProsthetic cardiac valvesDisseminated intravascular coagulationHeparin-induced thrombocytopeniaAntiphospholipid antibody syndromeLower risk for thrombosisCardiomyopathyNephrotic syndromeHyperstrogenic states (pregnancy and postpartum)Oral contraceptive useSickle cell anemiaSmoking
Blood