Which of the following is characterstic sign of diabetic retinopathy?
Increase in pericytes
Thinned out capillary basement membrane
Lipohyaline deposits
Proliferation of endothelial cells
The pathogenesis of Diabetic retinopathy is microangiopathy which occurs due to microvascular occlusion & leakage. There is degeneration and loss of pericytes in capillaries--> microvascular proliferation of endothelial cells -->thickening of basement membrane-->narrowed lumen of vessels.
Retina