In patient with Vulval ulcer. Which of the following will lead to malignancy?
HSV1
HSV2
STD
HPV
Ans. (d) HPVRef. William's Gyenecology Ch 31HPV (16, 18) most comman cause of vulvar carcinoma.* HPV infects the female - vulva, vagina, and cervix* Male- urethra, penis, and scrotum.* Both genders -Perianal, anal, and oropharyngeal area.Salient Features of Vulvar CancerMC site- labia majora and minoraMC symptom pruritus.MC type- SCC, epidermoid type (same for vaginal CA)MC implicated factor- HPV 16,18.Premalignant lesion of vulva * VIN (MC) vulvar intraepithelial lesion* /ts ds* Condyloma accuminata* Lichen sclerosis* Erythroplasia of querat* Bowen disease (type of VIN)MC mode of spread- lymphatic1st LN- superficial inguinal LN2nd LN- deep inguinal LN
Valva