Lesions of which of the hypothalamic nuclei cause diabetes insipidus?
Dorsomedial nuclei
Supraoptic and paraventricular nuclei
Median preoptic nuclei
Ventromedial nuclei
- Vasopressin, a 9-amino-acid peptide, has both anti-diuretic and vascular pressor activity - It is synthesized in the paraventricular & supraoptic nuclei of the hypothalamus. - Deficiency of Vasopressin causes Diabetes insipidus. - DI results in Polyuria & polydipsia Satiety center Ventromedial nuclei (VMN) Reward centre Medial forebrain bundle Circadian rhythm Suprachiasmatic nucleus Oxytocin Paraventricular nucleus
Disorders of Pituitary Gland