A 43 year old male is diagnosed with Schizophrenia but he refused to take treatment. Which of the following antipsychotic drug is the treatment of choice for this patient?
Clozapine
Risperidone
Olanzapine
Fluphenazine
Ans. (d) FluphenazineRef : Harrison 19th ed. 12722Fluphenazine can be given as monthly intramuscular depot preparation. Thus it is preferred in non-compliant patients.Important Points Regarding Anti-Psychotic Agents* Fluphenazine (enanthate and decanoate) and haloperidol (decanoate) are long-acting injectable (s.c. or i.m) forms of typical antipsychotics.* Risperidone is the first atypical antipsychotic available in long-acting injectable form.* Most commonly used antipsychotic by intravenous route is haloperidol* Ziprasidone, aripiprazole, asenapine and iloperidone has negligible risk to cause metabalic adverse effects (weight gain, hyperlipidemia and new onset diabetes mellitus)* Asenapine, paliperidone and ziprasidone has greatest potential to prolong QT interval.
Schizophreniform Disorder