Earliest evidence of healing in rickets is provided by-
S. Ca++
S. P043-
Radiological examination of growing bone ends
S Alkaline phosphate level
The earliest evidence of healing rickets comes from radiographs of the growing ends of bones. Concentration of calcium and phosphorus in the plasma provide an inconstant and unreliable guide. A more constant change is a decrease in the plasma alkaline phosphatase, but this does not usually occur for several weeks after adequate treatment initiated.