Which of the following liver enzymes is predominantly mitochondrial?
SGOT (AST)
SGPT (ALT)
GGT
5' Nucleotidase
In old literature, it was called as serum glutamate oxaloacetate transaminase (SGOT). AST needs pyridoxal phosphate (vitamin B6) as co-enzyme. Normal serum level of AST ranges from 8 to 20 U/L. It is a marker of liver injury and shows moderate to the drastic increase in parenchymal liver diseases like hepatitis and malignancies of the liver.Ref: DM Vasudevan, Page no: 269
Enzymes