Cardiac conduction defect seen with Tricyclic antidepressants are due to-
NE & serotonin uptake inhibitor
Antimuscarinic action on hea
Only NE uptake inhibition
Both NE uptake inhibition and antimuscarinic action on hea
Ans. is 'd' i.e., Both NE uptake inhibition and antimuscarinic action on hea o The commonest cardiovascular effect of tricyclic antidepressant overdose is sinus tachycardia, which is attributable to the inhibition of norepinephrine reuptake and the anticholinergic action.