18 year old girl with primary amenorrhea having a karyotype of 45X0 presents with infantile uterus. What should be done next?
B/L gonadectomy
H to induce pubey
Clitoroplasty
Vaginoplasty
Primary amenorrhea with karyotype of 45 XO with an infantile uterus is suggestive of TURNER SYNDROME Management Screen for associated abnormalities: cardiac (30% have coarctation of aoa), renal (esp.horseshoe kidney), autoimmune abnormalities (thyroiditis), diabetes, hypeension and hearing loss Growth hormone therapy: accelerate growth velocity and improves final height Gonadal steroids: sta with estrogen therapy and add progesterones to induce pubey
Gynaecology