Antimitochondrial antibodies are found in 90% of patients with
Primary biliary cirrhosis
Chronic active hepatitis
Seminoma
Choriocarcinoma
The most characteristic immunologic abnormality associated with primary biliary cirrhosis is the presence of antimitochondrial antibodies, which are found in 90% of affected individuals.This antibody is predominantly IgG. Antimitochondrial antibodies also can be detected in persons with other liver diseases but with a much lower frequency (less than 10%) and usually in low titer.
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