Tricyclic antidepressant are contraindicated in:
Glaucoma
Brain tumor
Bronchial asthma
Hypeension
Due to anticholinergic action, TCAs should be avoided in glaucoma These agents block muscarinic acetylcholine receptors, resulting in anticholinergic effects (e.g., dry mouth, blurred vision, urine retention, constipation); they are contraindicated in patients with glaucoma.
Mood Disorders