Hereditary retinoblastoma develop as a result of which of the following chromosomal deletion?
13q 14
13p 14
14p 13
14q 13
Hereditary retinoblastomas develop from the deletion of Rb gene, located on chromosome 13q14. Retinoblastoma gene is a tumor suppressor gene, which serves as a break on the advancement of cells from the G1 to S phase of cell cycle.Ref: Robbins Pathologic Basis of Disease, 7th Edition, Pages 287, 289, 1372.