A 60 years old male alcoholic presents with acute upper GI bleeding following bouts of vigrous vomiting. Most probable diagnosis is
Acute gastritis
Boerhaave's syndrome
Mucosal and submucosal tear at cardiac orifice of stomach
Esophageal carcinoma
Answer- C. Mucosal and submucosal tear at cardiac orifice of stomachMallory - Weiss syndromeIs characterized by mucosal tear at the gastroesophageal junction following a bout of forceful retching (or vomiting, coughing or straining.The clinical picture consists of acute upper gastrointestinal bleeding following bouts of retching or vomitting.Other frequent associations with Mallory-Weiss tears areHiatal herniaNSAIDs abuseDisease related bleeding diathesis.