Hydroxylation of proline in collagen requires which of the following:
Vitamin C
Fe2++
a-ketoglutarate
All of the above
Ans. D. All of the aboveProline and Lysine are hydroxylated to form hydroxyl proline and hydroxyl lysine in the presence of enzyme hydroxylase and requires Fe2++' ascorbic acid (Vitamin C), oxygen and a- ketoglutarate.
Vitamins and Minerals