In argininosuccinase deficiency, what should be supplemented to continue the urea cyce -
Aspartate
Arginine
Citrull in
Argininosuccinate
Ans. is 'b' i.e., Arginine o Argininosuccinase (argininosu coin ate lyase) catalyses the cleavage of arginiosuccinate into arginine and fumarate.o Thus, in argininosuccinase deficiency arginine cannat be produced.o Supplementation with arginine base helps replenish this amino acid.
Amino Acid Metabolism