Defects in Enterohepatic Circulation of Bile Acids due to the altered canalicular function is seen in:
Cirrhosis
Primary biliary cirrhosis
Gilbe's syndrome
Dubin johnson syndrome
Defects in Enterohepatic Circulation of Bile Acids Decreased Bile acid synthesis is affected in Cirrhosis decreased Biliary secretion due to Altered canalicular function Primary biliary cirrhosis Ref: Harrison, E-18, P-2462.