Murphy's sign is seen in
Acute cholecystitis
Cholangiocarcinoma
Cholangitis
Periampullary cancer
In the acute cholecystitis, the patient may have right upper quadrant tenderness that is exacerbated during inspiration by the examiner's right subcostal palpation (Murphy's sign). A positive Murphy's sign suggests acute inflammation and may be associated with a leukocytosis and moderately elevated liver function tests.Ref: Bailey and love 27e pg: 1199
General surgery