All of the following are true for patients of ulcerative colitis associated with primary sclerosing cholangitis (PSC), EXCEPT:
They may develop biliary cirrhosis
May have raised alkaline phosphatase
Increased risk of hilar Cholangiocarcinoma
PSC reves after a total colectomy
Colectomy for colitis makes no difference to the course of primary sclerosing cholangitis. Inpatients with associated ulcerative colitis the course of each disease seems independent of the other. Ref: Schwaz Principles of Surgery, 8th Edition, Page 1210