Synthesis of an immunoglobulin in membrane bound or secretory form is determined by:
One turn to two turn joining rule
Class switching
Differential RNA processing
Allelic exclusion
Ans. is 'c' i.e., Differential RNA processing (Ref: Kuby Immunolo 6th/e, p. 130 - 131)* Differential RNA processing of a common primary transcript determines whether the secreted or membrane form of an immunoglobulin will be produced.* Membrane bound or secreted form of immunoglobulin differs in the amino acid sequence of the heavy chain carboxyl terminal domains.
Immunology