Which coenzyme is responsible for carboxylation reaction?
Biotin
FAD
NADH
Thiamine pyrophosphate
Ans. is 'a' i.e. biotin Biotin is the coenzyme required for enzymes that are involved in carboxylation reactions, e.g. acetyl-CoA carboxylase and pyruvate carboxylase.* Most coenzymes are derived from vitamins. Below is given list of vitamins, derived coenzymes and the reactions they are involved in: VitaminCoenzymeReaction typeBi (Thiamine)TPP (thiamine pyrophosphate)Oxidative decarboxylation, transketolationB2 (Riboflavin)FMN, FADOxidation/ReductionB3(Pantothenate)CoA-Coenzyme AAcyl group transferB6 (Pyridoxine)PLP (Pyridoxal phosphate)Transfer of groups to and from amino acids (Transamination,Deamination, Condensation, Decarboxylation)Bj2 (Cobalamin)5-deoxyadenosyl cobalamin,methylcobalaminIsomerization of methylmalonyl, synthesis of mehionineNiacinNAD+, NADP+Oxidation/ReductionFolic acidTetrahydrofolateOne carbon group transferBiotinBiotinCarboxylationVitamin KVitamin KCarboxylation of glutamic acid residues
Vitamins