Delayed puberty is seen in
Hypothyroidism
Turnur's syndrome
Malabsorbtion syndrome
Chronic disease
Delayed puberty may be related to chronic, reversible causes like systemic disease, malnutrition,eating disorders,hyperprolactinemia,and hypothyroidism.Irreversible defects include the destruction of the hypothalamic-pituitary axis by infection, surgery, tumour. All these are due to chronic disease.