An immunocompromised person presents to PGI with history of seizures had an MRI that revealed a temporal lobe lesion. Brain biopsy results showed multinucleated giant cells with intranuclear inclusions. The most probable cause of the lesion is:
Hepatitis C virus
Herpes simplex virus
Listeria monocytogenes
Coxsackievirus
The most probable cause of the lesion is Herpes simplex virus. It causes primary and recurrent disease. Encephalitis, which usually involves the temporal lobe, has a high moality rate. Severe neurologic sequelae are seen in surviving patients. Giant multinucleated cells are typically found at the base of the Herpes virus lesion.
Virology (General Propeies, DNA Viruses)