Which of the following are the extraintestinal manifestations of Sipple syndrome?
Cutaneous lichen
Amylodosis
Hirschsprung disease
All the above
Ans. is 'd' i.e., All the aboveMultiple Endocrine Neoplasia (MEN) Syndromes MEN I(Werner syndrome)MEN 2A(Sipple syndrome)MEN 2BPituitaryAdenomas, Hyperplasia----ParathyroidHyperplasiaAdenomasHyperplasia or adenoma--Pancreatic isletsHyperplasiaAdenomasCarcinomas----AdrenalCortical hyperplasiaPheochromocytomaPheochromocytomaThyroid--C-cell hyperplasiaMedullary carcinomaC-cell hyperplasiaMedullary carcinomaExtraendocrine* Foregut carcinoid* Subcutaneous or visceral* Dermal angiofibroma or collagenomaCutaneous lichen amyloidosisHirschsprung diseaseMucosal and gastro intestinal neuroma, ganglio-neuromas,Marfanoid habitusMutant gene locusMEN IRETRET
Endocrinology