Not a specific tumor marker is -
CD 99
HMB 45
b- globulin
CEA
Ans is 'd' i.e., CEA Carcinoembryonic antigen (CEA) is used as tumor marker for colorectal cancer (major use), lung cancer, breast cancer and ovarian cancer.It is alsoincreased in non-neoplastic conditions like alcoholic cirrhosis, hepatitis, IBD (CD, UC), smoking and pancreatitis.CEA lacks sensitivity as well as specificity, hence cannot be used to confirm the diagnosis.About other optionsCD 99 - specific marker for Ewing's sarcomaHMB 45 - specific marker for malignant melanomab - globulin - specific marker for multiple myeloma