Which among the following is the most common tumor associated with neurofibromatosis in a child?
Juvenile myelomonocytic leukemia
Acute lymphoblastic leukemia
Acute monocytic leukemia
Acute myeloid leukemia
Patients with neurofibromatosis type 1 and Noonan syndrome have a predilection for JMML, since they have germline mutations involved in RAS signaling. AML and ALL are associated with DOWN syndrome.
Neurocutaneous syndromes