Direct Coomb's test is positive in hemolytic anemia due to:
Paraxysmal cold hemoglobinuria
Paroxysmal nocturnal hemoglobinuria
Idiopathic thrombocytopenic purpura
Hemolytic uremic syndrome
Paroxysmal cold hemoglobinuria: Caused by the presence of cold-reacting autoantibodies (anti-P Ab) in the blood - Hence, Direct coombs test is positive. Characterized by the sudden presence of hemoglobinuria, typically after exposure to cold temperatures.
Hemolytic anemia