Which of the following ultrasound marker is associated with greatest increased risk for Trisomy 21 in fetus:
Echogenic foci in hea
Hyperechogenic bowel
Choroid plexus cysts
Nuchal skin fold
Increased nuchal skin fold confers the highest risk of aneuploidy and is the most powerful second trimester ultrasound marker, > 99% specificity for Down Syndrome. The probability of Down Syndrome is increased when multiple soft markers are present.
ULTRASOUND