A 38 year old male known case of type 2 DM was staed on oral hypoglycemic drugs. After few days he comes back to OPD with complains of urge to drink water excessively and increased frequency of micturition . He also complains of a burning sensation while urinating . Which drug could be the possible cause of the above mentioned symptoms?
Exenatide
Glipizide
Metformin
Dapagliflozin
Patient suffers from Urinary tract infection, Dapagliflozin is the causative drug here. Dapagliflozin It is a sodium-glucose co-transpoer-2 inhibitor Improve glycemic control by inhibiting glucose Inhibit glucose reabsorption in the proximal tubule of the nephron | result in Glucosuria | result in urinary tract infections(High glucose concentration in the urine can provide a rich source of nutrients for bacteria. Therefore, bacteria can multiply and make foundation for infection) S/E: UTI Dehydation Polyuria Exacerbate tendency to hyperkalemia and DKA
Diabetes Mellitus