Topical Mitomycin C is indicated in the treatment of which of the follwoing conditions?
Endoscopic treatment of angiofibroma
Treatment of skull base osteomyelitis
Sturge Weber syndrome
Treatment for laryngeal stenosis
Topical application of Mitomycin C after endoscopic dilatation of laryngotracheal stenosis prevents restenosis. Mitomycin-C (MMC) inhibits fibroblast proliferation and synthesis of extracellular matrix proteins, and thereby modulates wound healing and scarring.