Basic lesion in tobacco amblyopia is
lschaemia of optic nerve fibres
Degeneration of ganglion cells especially of macular region
Degeneration of foveal cones
All of the above
Tobacco amblyopia It typically occurs in men who are generally pipe smokers, heavy drinkers and have a diet deficient in proteins and vitamin B complex; and thence also labelled as 'tobacco-alcohol-amblyopia. Pathogenesis: The toxic agent involved is cyanide found in tobacco. Ref:- A K KHURANA; pg num:-296
Neuro-ophthalmology