If a diabetic patient being treated with an oral hypoglycemic agent develops dilutional Hyponatremia, which one of the following could be responsible for this effect
Chlorpropamide
Tolbutamide
Glyburide
Glimepride
Refer KDT 6 /e p 267 Chlorpropamide is a first generation Sulfonylureas It increases the risk of hypoglycemia Other adverse effects of Chlorpropamide are ADH like action leading to dilutional Hyponatremia Cholestatic jaundice Disulfuram like reaction
Endocrinology