Which antiepileptic drug leads to gingival hyperplasia:
Phenytoin
Carbamazepine
Valproate
Lamotrigine
Ans. A. PhenytoinPhenytoin causes gingival hyperplasia, hirsutism, megaloblastic anemia, osteomalacia. Carbamazepine causes agranulocytosis, valproate is hepatotoxic and also causes spina bifida. Lamotrigine is known to cause Steven Johnson syndrome.
C.N.S