Which of the following is an example for Transplacental carcinogenesis?
Vaginal Ca
Pancreatic Ca
Colon Ca
Breast cancer
Ref: Shaw's Textbook of Gynaecology, 15th ed. pg :52 Explanation:Transplacental carcinogenesis is a series of genotypic or phenotypic changes in the cells of a fetus due to in utero exposure to carcinogens.Adenocarcinoma (clear cell carcinoma) was seen in the vagina in children whose mothers took Diethylstilbesterol for threatened abortion.
Vigina