Non-invasive prenatal screening (NIPS) is paicularly useful in the modern era of diagnosis in clinical genetics. Which of the following statements is not true regarding this test?
Useful in screening for aneuploidies
Evaluates maternal blood for abnormalities
HIgh positive predictive value
Positive test need confirmation by invasive testing
Non-invasive prenatal screening (NIPS) has a high negative predictive value. NIPS: Useful in screening high-risk pregnancies for aneuploidies Done after 10 weeks of gestation Evaluates maternal blood for screening Positive tests need confirmation by invasive testing (like amniocentesis, Chorionic villous sampling) Ref: Ghai essential pediatrics 9th edition Pgno: 643
Genetic and genetic disorders