A 30 year old male presented with pain in lower extremities, aggravated by walking. He gives the history of cigarette smoking. In this patient prevalence of which histocompatibility antigen is increased?
HLA-B5
HLA-B8
HLA-DR2
HLA-DR3
The history suggests that the patient is suffering from Buerger disease. There is increased prevalence of HLA-A9 and HLA-B5 in these patients. HLA DISEASE HLA-B8 Myasthenia gravis, Graves Disease HLA-DR2 Narcolepsy HLA-DR3 Myasthenia gravis, Celiac sprue HLA-DR4/DW4 Rheumatoid ahritis