A 70yr old male has a pathological fracture of femur. The lesion appears a lytic on X- rays film with a circumscribed punched out appearance .The curetting from fracture site is most likely to show which of the following?
Diminshed and thinned trabecular bone
Sheets of atypical plasma cells
Metaplastic prostatic adenocarcinoma
Malignant cells forming osteoid bone
Olf patients along with lytic circumscribed punched our X- rays appearance suggests multiple myeloma. Multiple myeloma most often presents as multifocal destructive bone tumours composed of plasma cells throughout the skeletal system.(ref Robbins 9/e p599,7/679)
Haematology