Pelger Huet anamoly shows presence of -
Hyposegmented neutrophil
Hypersegmented neutrophil
Unsegmented neutrophil
None of the above
Ans. is 'a' i.e., Hyposegmented neutrophil Pelger Huet anomalyo It is a genetic disorder with an autosomal dominant inheritance pattern,o It is a blood laminopathy associated with the lamin B receptor.o It is characterized by a white blood cell type known as a neutrophil whose nucleus is hyposegmented.o Heterozygotes are clinically normal, although their neutrophils may be mistaken for immature cells, which may cause mistreatment in a clinical setting.o Homozygotes tend to have neutrophils with rounded nuclei that do have some functional problems.
Misc. (W.B.C)