All are liver function test alterations in bacterial sepsis, EXCEPT:
Elevation of bilirubin with normal liver enzymes
LFT alteration is due to the endotoxemia
Endotoxemia impairs transpo of anions, resulting in impaired bile flow
Jaundice is always associated with leukocytes
JAUNDICE IN BACTERIAL SEPSIS (1) Dispropoionate increase in serum bilirubin compared to aminotransferase and ALP (2) It can appear even without fever / hypotension, Leukocytosis (3) Mechanisms : Endotoxin mediated cytokine activation (4) It impairs transpo of anions in both sinusoidal and canalicular membranes resulting in impaired bile flow Ref: schiff's diseases of liver : E - 11, P - 232.