Chronic Active Hepatitis is most reliably distinguished from chronic Persistant hepatitis by the presence -
Extrahepatic manifestation
Significant titre of antismooth muscle antibody
Characteristic liver histology
Hepatitis B surface antigen
Ans. is 'c' i.e., Characterstic liver histologyMinimal chronic hepatitis (previously called chronic persistent hepatitis)The poal chronic inflammation is mild and is restricted to the paal triads without extension into the Liver lobule across the limiting plate.Chronic active hepatitis-4 characterized by continuing necrosis of Liver cells. The severe inflammation disrupts the limiting plate.