Primary Structural defect of an organ is termed:
Malformation
Disruption
Deformation
Association
Primary structural defect of an organ is called as malformation. Primary malformations are caused by endogenous disturbances of the primordial tissues. Secondary malformations (disruptions) arise when organs develop abnormally from a normal primordium. Ref: Tanley L. Robbins, Ramzi S. Cotran, (2012) , Chapter 1, "Cell Injury", In the book, "Pocket Companion to Robbins and Cotran Pathologic Basis of Disease", 8th Edition, USA, Page 27 ; Robbin's Basic Pathology, 7th Edition, Pages 470-71