True about sickle anemia is -
Leucopenia
Decreased ESR
Microcardia
Ringed sideroblast
Answer- B. Decreased ESRInvestigations in sickle cell anemia-Peripheral smear shows sickle cells, target cell and Howell - Jolly bodies.ESR is decreasedPositive sickling testHb electrophoresis shows two bands in heterozygous state/sickle cell trait.Bone changes on X-ray show:-A. Fish mouth veebraeB. Crew hair cut (hair on end) appearance of skull.('Hair on end appearance' is also seen in thalassemia, hereditaty spherocytosis and G6PD deficiency.)Gamma Gandy bodies