The difference between iron sorbitol-citric acid and iron dextran is that the former:-
Cannot be injected i.v.
Is not bound to transferrin in plasma
Is not excreted in urine
Produces fewer side effects
Iron sorbitol citrate should not be used i.v. because it may rapidly saturate the transferrin receptors and which can result in Iron toxicity due to more free Iron. IRON - DEXTRAN IRON-SORBITOL-CITRATE can be given i/v or i/m only i/m not excreated in urine about 30% excreated in urine absorbed through lymphatics absorbed directly in circulation not bound to transferrin bound to transferrin & may saturate it when given in high doses
Hematology