Adverse effects of insulin include all of the following except:
Edema
weight loss
Lipodystrophy
hypoglycemia
Hypoglycemia is the most frequent and potentially the most serious relationship of insulin therapy. Some patients develop sho lived dependent edema. Lipodystrophy occur at the site of injection after a long time. weight gain can occur due to insulin not weight loss (REF.Essential of medical pharmacology K D TRIPATHI 6 Edition, Page No - 262)
Endocrinology