With increase in age which of the following is true for lungs?
Pulmonary compliance increases
Residual volume decreases
Mucociliary clearance increases
Fibrous of interstitium decreases
Anatomical and Physiological changes of respiratory system with ageing: Anatomical Air space size: Increased Compliance Chest wall compliance : Decreased Lung compliance: Increased to unchanged Total respiratory system compliance: Decreased Muscle strength Maximum inspiratory pressure(MIP): Decreased Trans diaphragmatic pressure (Pdi): Decreased Maximum voluntary ventilation (MVV): Decreased Lung Function FEV1: Decreased FVC: Decreased TLC: Unchanged Vital capacity: Decreased Functional residual capacity: Increased Residual volume: Increased DLCO/VA: Decreased Excercise capacity VO2 max: Decreased Dead space ventilation: increased Immunology Bronchial fluid Neutrophils %: Increased Ratio of CD4+/CD8+ cells: Increased Epilthelial lining fluid antioxidants: Decreased Ref: Guyton and Hall Textbook of Medical Physiology 13th edition Pgno: 499
Respiratory system