Stimulation of which of the following areas of brain is experimentally used to control intractable pain
Periaqueductal grey matter
Mesencephalon
Subthalmic nucleus
Medical fore brain bundle
ganong's review of medical physiology 24th edition . *mesencephalic periaqueductal gray(PAG) is pa of descending pathway that modulates pain transmission by inhibition of primary afferent transmissiion in the dorsal horn of spinalcord *PAG neurons project directly to and activate two groups of neurons in brainstem:neurons in nucleus raphe magnus and in rostral ventromedial medulla . *neurons from both region project to dorsal horn and inhibit dorsal horn neuron activity.
C.N.S