Which of the following is an inhibitor of dihydrofolate reductase -
Phenytoin
Alcohol
Methotrexate
Yeast
Ans. is 'c' i.e., Methotrexate Drugs causing folate deficiencyInterference with folic acid absorptionInhibition of dihydrofolate reductaseImpair folate metabolismo Phenytoino Phenobarbitoneo Primidoneo Sulfasalazineo Cotrimoxazoleo Methotrexateo Pyrimethamineo Triametereneo Pentamidineo Trimethoprimo Alcohol
Anti-Neoplastic Agents