Which of the following enzymes, requires Biotin as the coenzyme
Pyruvate Dehydrogenase
Pyruvate Kinase
Pyruvate Carboxylase
PEP Carboxy Kinase
Pyruvate enters the mitochondrion and is carboxylated to oxaloacetate by pyruvate carboxylase, an ATP-dependent reaction in which the coenzyme is the Vitamin biotin.Ref: Harper&;s Biochemistry; 30th edition; Chapter 16; The Citric Acid Cycle: The Central Pathway of Carbohydrate, Lipid & Amino Acid Metabolism
Structure and function of protein