All of the following statements about sodium fluoride in otosclerosis are true, except:
Acts by inhibiting Proteolytic enzymes in cochlea
Acts by inhibiting osteoblastic activity
Is contraindicated in chronic nephritis
Is indicated in patients with a positive Schwaze sign
In active cases i.e. when Schwaze sign is present, medical management with sodium fluoride (Na F) is done. Na F accelerates the maturation of the focus by increasing osteoblastic and decreasing osteoclastic activity. It also inhibits the proteolytic enzymes that release cytotoxic chemicals to cochlea.
Otosclerosis