Which of the following hematological condition is depicted below?
Multiple myeloma
Megaloblastic anemia
Chronic myeloid leukemia
Metastasis
Ref. Robbins Pathology. 9th edition. Page. 620
 
The picture shows many atpical plasma cells – Diagnostic of Myeloma

Malignant proliferation of plasma cells characterised by monoclonal gammaglobulinaemia (paraproteinaemia)
Cell of origin – Post germinal centre B cells
Stages
	
MGUS
Smoldering myeloma
Myeloma


MGUS – most common plasma cell dyscrasia
Myeloma – CRAB Features
	
Hypercalcemia
Renal Insufficiency
Anemia
Bone lytic lesions