Which of these is a feature of hemorrhagic disease of new born?
Prolonged prothrombin time
Defective platelet count
Prolonged bleeding time
Prolonged thrombin time
Normal newborns are moderately deficient in vitamin K. This deficiency increases on 3rd to 5th day when, vitamin K level falls fuher. The serum level of vitamin K stas increasing from 13th to 15th day of life and achieves adult level at 3 months. In hemorrhagic disease of the newborn, there is delay in achieving the normal vitamin K level. Prolongation of PT values is the most common and earliest finding in vitamin K-deficient patients due to reduction in prothrombin, factor VII, IX, and X levels. F VII has the shoest half-life among these factors that can prolong the PT before changes in the aPTT.
Platelet & Coagulation disorders