FFP not used in -
TTP
Factor XII deficiency
Vitamin K deficiency
Antithrombin III deficiency
Ans. is 'b' i.e., Factor XII deficiency Fresh frozen plasma (FFP)o FFP is defined as the fluid portion of human blood that has been centrifuged, separated, and frozen solid at -18degc within 6 hours.o FFP contains stable coagulation factors and plasma proteins : -(i) Fibrinogen(ii) Antithrombin(iii) Albumin & Immunoglobulin(iv) Protein C, S.(v) Factor II, V, VII, IX, X, XIo Indications for the use >>f FFP are : -Deficiencies of factor II, V, VII, IX, X and XI when specific component therapy is neither available nor appropriate.Emergency reversal of warfarin effect.In vit K deficiency as replacement for Vit K dependent factors (II, VII, IX, X)Antitbrombin III deficiencyAfter massive blood transfusion.In immunodeficiency as a source of immunoglobulinTTPNote : Options 'c', is partially correct, FFP can be used for deficiency of factor IX but not for factor VIII.
Bleeding Disorders