Vigabatrin acts through -
decreasing GABA uptake at synaptic cleft
Increasing GABA uptake at synaptic cleft
GABA transaminase inhibitor
GABA transacetylase inhibitor
Ans. is 'c' i.e., GABA transaminase inhibitor Vigabatrin (g vinyl GABA)* It is a newer anti - convulsant which is an inhibitor of enzyme GABA transaminase; it thus increases GABA concentration at synapse.* It is mainly used in patients with refractory epilepsy visual field defects and behavioural changes restricts its use.
C.N.S