A 17-year-old girl had been taking a drug for treatment of acne for the last 2 years, which has lead to pigmentation. Which drug could it be?
Doxycycline
Minocycline
Azithromycin
Chlorpromazine
Ans. (B) Minocycline(Ref: Harrison 17th/e p327-328, CMDT-2010/121)Both minocycline as well as chlorpromazine can cause pigmentation on long-term use.However, as the patient in question is being treated for acne, the answer should be minocycline. Antibiotics used in acne are erythromycin, clindamycin, tetracycline, doxycycline and minocycline.
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