Which of the following is the drug of choice for the treatment of syndrome of inappropriate Antidiuretic Harmone secretion?
Demeclocycline
Vasopressin
Thiazide diuretics
Chloropropamide
SIADH is due to excessive secretion of anti-diuretic hormone. It is diametrically opposite disease to diabetes insipidus. Vasopressin, Thiazide and chloropropamide are used for the treatment of diabetes insipidus whereas demeclocycline is used for SIADH management.Now-a-days,vasopressin receptor antagonists like tolvapton and conivaptan are preferred for SIADH.
Endocrinology