True about estrogen production in menstural cycle?
Only by theca cells
Only by granulosa cells
Both theca and granulosa cells
None of the above
Ans. is 'c' i.e., Both theca and granulosa cells Ovarian follicle contains two types of cells in preovulatory phase :-i) Granulosa cells :- Secrete mainly estrogen and very minimal amount of progesterone.ii) Theca cells (interna & externa) Theca interna cells provide androgen and pregnenolone to granulosa cells to conve them into estrogen and progesterone respectively.After ovulation, corpus luteum contain two types of cell :-i) Granulosa luteal cells (formed by luteinization of granulosa cells) :- Produce mainly estrogen and minimal progesterone.ii) Theca luteal cells (formed by luteinization of theca interna cells) :- Produce mainly progesterone.