True about Hodgkin's lymphoma are all except?
Often localized to single axial group of lymph nodes
Hepatomegaly is always present
Contiguous spread of lymph nodes
Can be cured by Chemotherapy and Radiotherapy
HODGKIN'S LYMPHOMA : - HL arises in lymphoid tissue & spreads to adjacent lymph node areas in a relatively orderly fashion. -Patients commonly present with painless, non-tender, firm, rubbery, cervical or supraclavicular lymphadenopathy and usually some degree of mediastinal involvement. HEPATOSPLENOMEGALY IS A FEATURE BUT NOT ALWAYS PRESENT - Chemotherapy & radiation therapy are both effective in treatment of HL. TREATMENT- A- Adriamycin (Doxorubicin) B - Bleomycin V - Vinblastine D - Dacarbazine
Neoplastic disorders of WBCs