The ligand-receptor complex dissociates in the endosome because
Of its large size
The vesicle looses its clathrin cost
Of the acidic pH of the vesicle
Of the basic pH of the vesicle
Ligand-gated channels are opened by binding of effectors. The binding of a ligand to a receptor site on the channel results in the opening (or closing) of the channel (Fig. 2.11). The ligand may be an extracellular signaling molecule or an intracellular messenger.Ref: DM Vasudevan, page no: 15
membrane structure and function