Patient undergoing surgery was given a muscle relaxant. It produced marked fall in B.P. and increase in airway resistance which were reversed with diphenhydramine. The muscle relaxant was most probably:
Pancuronium
Diazepam
Tubocurarine
Vecuronium
Hypotension and bronchoconstriction (increase in airway resistance) are impoant adverse effects caused by histamine. This is confirmed to be due to histamine because of reversal with diphenhydramine. * Maximum histamine release is caused by d-tubocurarine. * Vecuronium does not cause histamine release, therefore is preferred agent in asthmatic patients.
Anaesthesia