True statement regarding development of drug resistance in MRSA is?
Results due to penicillinase enzyme production
Occurs due to change in penicillin blinding proteins
Chromosome mediated
Treated with amoxicillin + clavulanic acid
MRSA have emerged in many areas. These are insensitive to all penicillinase-resistant penicillins and to other beta-lactams as well as to erythromycin, aminoglycosides, tetracyclines, etc. The MRSA have altered PBPs which do not bind penicillins. ESSENTIALS OF MEFICAL PHARMACOLOGY page no 721
Chemotherapy