A foueen year old body is admitted with history of fever, icterus, conjunctival suffusion and haematuria for twenty days. Which of the following serological test can be of diagnostic utility -
Widal test
Microscopic Agglutination Test
Paul Bunnell test
Weil felix reaction
Ans. is 'b' i.e., Microscopic agglutination test History of fever, jaundice (icterus), bleeding diathesis (conjuctival suffusion) and renal dysfunction (hematuria) are suggestive of Weil's disease (severe Leptospirosis). A definite diagnosis of leptospirosis is based either on isolation of the organism from the patient or on seroconversion or a rise in antibody titer in microscopic agglutination test (MAT).