All of the following are Indications for CSF examination in adults with all stages of Syphilis Except
RPR titer >= 1:32
VDRL titer < 1:32
Active teiary syphilis
Suspected treatment failure
Indications for Cerebrospinal Fluid Examination in Adults with All Stages of SyphilisAll PatientsAdditional Indications in HIV-Infected Persons1. Signs or symptoms of nervous system involvement (e.g., meningitis, hearing loss, cranial nerve dysfunction, altered mental status, ophthalmic disease , ataxia, loss of vibration sense), or2. RPR or VDRL titer >=1:32, or3. Active teiary syphilis, or4. Suspected treatment failure11. CD4+ T cell count <=350/mL, or2. All HIV-infected persons (recommended by some expes)Reference: Harrison&;s Principles of Internal Medicine; 19th edition; Chapter 206; Syphilis
Bacteriology