Year
int64 2.02k
2.03k
| UI
stringlengths 7
10
| UPDATED_FIELD
stringclasses 13
values | REPLACED_VALUE
stringlengths 1
912
| REPLACEMENT_VALUE
stringlengths 1
910
| NOTES
stringclasses 19
values |
---|---|---|---|---|---|
2,023 |
C469610
|
SO
|
HIV Clin Trials 2002 Jul-Aug;3(4):272-8
|
J R Soc Health 1991 Oct;111(5):170-1
|
Source updated on a SCR
|
2,023 |
C469610
|
SO
|
J R Soc Health 1991 Oct;111(5):170-1
|
HIV Clin Trials 2002 Jul-Aug;3(4):272-8
|
Source updated on a SCR
|
2,023 |
C469995
|
NM
|
N-methanocarbathymidine
|
(north)-methanocarbathymidine
|
Preferred Term (NM) updated on an scr
|
2,023 |
C469995
|
NO
|
structure in first source
|
also called NMCT
|
Note updated on a SCR
|
2,023 |
C470703
|
NM
|
Nth1 protein, mouse
|
Nthl1 protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C473608
|
NM
|
daf-28 protein, C. elegans
|
daf-28 protein, C elegans
|
Preferred Term (NM) updated on an scr
|
2,023 |
C475934
|
NO
|
RN given for (3R-trans)-isomer; suppresses expression of both HBsAg and HBeAg; structure in first source
|
suppresses expression of both HBsAg and HBeAg
|
Note updated on a SCR
|
2,023 |
C477447
|
NO
|
has antineoplastic activity; structure in first source
|
has antineoplastic activity
|
Note updated on a SCR
|
2,023 |
C477447
|
SY
|
Tussafug
|
benproperine pamoate
|
Synonym updated on an scr
|
2,023 |
C479566
|
NM
|
LPP3 protein, mouse
|
Plpp3 protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C479748
|
NO
|
GenBank AJ536192
|
RefSeq NM_001170799
|
Note updated on a SCR
|
2,023 |
C479935
|
NO
|
an HIV inhibitor; structure in first source; disrupts late step in processing HIV Major Core Protein p24, preventing the capsid precursor p25 from being converted to mature capsid p24
|
an HIV inhibitor; disrupts late step in processing HIV Major Core Protein p24, preventing the capsid precursor p25 from being converted to mature capsid p24
|
Note updated on a SCR
|
2,023 |
C479935
|
SO
|
Proc Natl Acad Sci U S A 2003 Nov 11;100(23):13555-60
|
Retrovirology. 2004 Jun 29;1(1):15
|
Source updated on a SCR
|
2,023 |
C479935
|
SO
|
Retrovirology. 2004 Jun 29;1(1):15
|
Proc Natl Acad Sci U S A 2003 Nov 11;100(23):13555-60
|
Source updated on a SCR
|
2,023 |
C480040
|
RN
|
0
|
EC 2.3.2.27
|
Registry number updated on an SCR
|
2,023 |
C480499
|
NM
|
NHE protein, mouse
|
Slc9c1 protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C480499
|
NO
|
sperm-specific Na+H+ exchanger required for sperm motility and fertility; GenBank AY368685
|
RefSeq NM_198106
|
Note updated on a SCR
|
2,023 |
C482089
|
NM
|
laeverin, human
|
LVRN protein, human
|
Preferred Term (NM) updated on an scr
|
2,023 |
C482089
|
NO
|
expressed in extravillous trophoblasts, belongs to membrane-bound gluzincin metallopeptidases; has a peptidase M1 motif containing a zinc-binding active site; amino acid sequence in first source
|
expressed in extravillous trophoblasts, belongs to membrane-bound gluzincin metallopeptidases; has a peptidase M1 motif containing a zinc-binding active site; amino acid sequence in first source; RefSeq NM_173800
|
Note updated on a SCR
|
2,023 |
C483025
|
NM
|
Dfy protein, mouse
|
Ackr1 protein mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C484810
|
NM
|
Tozasertib
|
tozasertib
|
Preferred Term (NM) updated on an scr
|
2,023 |
C484810
|
NO
|
a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth; structure in first source
|
a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth
|
Note updated on a SCR
|
2,023 |
C484876
|
NO
|
see scutellarein for aglycone; structure in first source
|
see scutellarein for aglycone
|
Note updated on a SCR
|
2,023 |
C485800
|
NO
|
from Maclura pomifera; structure in first source
|
from Maclura pomifera
|
Note updated on a SCR
|
2,023 |
C486070
|
NM
|
Tcfcp2l1 protein, mouse
|
Tfcp2l1 protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C486182
|
NO
|
an estrogen receptor modulator
|
a selective estrogen receptor beta agonist or modulator. also called DPN compound
|
Note updated on a SCR
|
2,023 |
C486182
|
SO
|
Br J Pharmacol. 2003 Aug;139(7):1249-53
|
Neuroendocrinology. 2004;79(5):247-58
|
Source updated on a SCR
|
2,023 |
C488674
|
RN
|
0
|
EC 2.3.2.27
|
Registry number updated on an SCR
|
2,023 |
C489251
|
RN
|
0
|
P0LE4QW0S6
|
Registry number updated on an SCR
|
2,023 |
C489251
|
SY
|
GW 5074
|
GW-5074
|
Synonym updated on an scr
|
2,023 |
C489897
|
NO
|
isolated from the fruit and twig of Aglaia silvestris; structure in first source
|
isolated from the fruit and twig of Aglaia silvestris
|
Note updated on a SCR
|
2,023 |
C492871
|
NO
|
a once-a-day, fixed-dose combination of Epivir and Ziagen
|
combination of Epivir and Ziagen
|
Note updated on a SCR
|
2,023 |
C493903
|
NO
|
recognized by monoclonal antibody 3H11; function unknown; GenBank AF317887; RefSeq NM_025114
|
recognized by monoclonal antibody 3H11; function unknown; GenBank AF317887; RefSeq NM_025114. mutation on cep290 protein gene associated with LEBER CONGENITAL AMAUROSIS 10.
|
Note updated on a SCR
|
2,023 |
C498826
|
NM
|
4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide
|
nilotinib
|
Preferred Term (NM) updated on an scr
|
2,023 |
C498826
|
NO
|
antineoplastic agent; structure in first source
|
antineoplastic agent
|
Note updated on a SCR
|
2,023 |
C498826
|
RN
|
0
|
F41401512X
|
Registry number updated on an SCR
|
2,023 |
C498826
|
SY
|
Tasigna
|
nilotinib hydrochloride hydrate
|
Synonym updated on an scr
|
2,023 |
C499686
|
NM
|
oxyS protein, E coli
|
oxyS small RNA, E coli
|
Preferred Term (NM) updated on an scr
|
2,023 |
C499686
|
NO
|
a small RNA regulator that negatively regulates rpoS translation and fhlA translation
|
a small RNA regulator that negatively regulates rpoS translation and fhlA translation; RefSeq NC_000913
|
Note updated on a SCR
|
2,023 |
C500926
|
NO
|
indole-ether quinazoline; vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor
|
vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor
|
Note updated on a SCR
|
2,023 |
C501326
|
NM
|
ALR-1 protein, C. elegans
|
ALR-1 protein, C elegans
|
Preferred Term (NM) updated on an scr
|
2,023 |
C501445
|
NM
|
Dlgh2 protein, mouse
|
Dlg2 protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C501445
|
NO
|
*INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS (2005-2011)
|
RefSeq NM_011807
|
Note updated on a SCR
|
2,023 |
C501451
|
NO
|
GenBank AF087696, RefSeq XM_340912
|
RefSeq NM_053513
|
Note updated on a SCR
|
2,023 |
C502014
|
RN
|
Ec 3.4.21.-
|
EC 3.4.21.-
|
Registry number updated on an SCR
|
2,023 |
C505045
|
NM
|
Tecovirimat
|
tecovirimat
|
Preferred Term (NM) updated on an scr
|
2,023 |
C505045
|
NO
|
a potent and specific inhibitor of orthopoxvirus replication
|
A potent and specific inhibitor of orthopoxvirus replication. It is used for the treatment of SMALLPOX and other orthopoxvirus infections, including MONKEYPOX under expanded access investigational new drug protocol (https://www.cdc.gov/poxvirus/monkeypox/clinicians/Tecovirimat.html).
|
Note updated on a SCR
|
2,023 |
C505045
|
NO
|
a potent and specific inhibitor of orthopoxvirus replication; structure in first source
|
a potent and specific inhibitor of orthopoxvirus replication
|
Note updated on a SCR
|
2,023 |
C505361
|
NO
|
induces apoptosis by targeting BCL2 & could be used for therapy of Bcl2-overexpressing tumors
|
RefSeq NR_029485 (A); RefSeq NR_029663 (B)
|
Note updated on a SCR
|
2,023 |
C505380
|
NO
|
structure in first source
|
non-immunosuppressive immunophilin ligand
|
Note updated on a SCR
|
2,023 |
C505380
|
RN
|
0
|
K0Z8830U95
|
Registry number updated on an SCR
|
2,023 |
C505734
|
NO
|
a TAK1 inhibitor
|
a TAK1 inhibitor; has anti-inflammatory activity; structure in first source
|
Note updated on a SCR
|
2,023 |
C505734
|
SO
|
Endocrinology 2005 Nov;146(11):4814-24
|
Int J Immunopharmacol 1999 Dec;21(12):799-814
|
Source updated on a SCR
|
2,023 |
C506426
|
NO
|
from Scutellaria baicalensis; structure in first source
|
from Scutellaria baicalensis
|
Note updated on a SCR
|
2,023 |
C507738
|
NM
|
HIM-8 protein, C. elegans
|
HIM-8 protein, C elegans
|
Preferred Term (NM) updated on an scr
|
2,023 |
C507827
|
NO
|
structure in first source
|
a macrocyclic polymer compound comprising 10 GLYCOLURIL units with methylene bridges
|
Note updated on a SCR
|
2,023 |
C507913
|
NM
|
KSRP protein, mouse
|
Khsrp protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C508040
|
LT
|
LAB
|
TRD
|
Lexical type updated on a SCR
|
2,023 |
C508066
|
NM
|
NAC2 protein, Arabidopsis
|
At3g15510 protein, Arabidopsis
|
Preferred Term (NM) updated on an scr
|
2,023 |
C508617
|
NM
|
PVF-1 protein, C. elegans
|
PVF-1 protein, C elegans
|
Preferred Term (NM) updated on an scr
|
2,023 |
C508854
|
NO
|
orally active neurokinin-1 receptor antagonist; structure in first source
|
orally active neurokinin-1 receptor antagonist
|
Note updated on a SCR
|
2,023 |
C508887
|
NO
|
a synthetic pleuromutilin; structure in first source
|
a synthetic pleuromutilin
|
Note updated on a SCR
|
2,023 |
C510728
|
RN
|
0
|
EC 3.6.4.12
|
Registry number updated on an SCR
|
2,023 |
C510763
|
NM
|
CIBZ protein, mouse
|
Zbtb38 protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C510763
|
NO
|
ortholog of ZENON protein from rat; GenBank DQ192019
|
ortholog of ZENON protein from rat; RefSeq NM_175537
|
Note updated on a SCR
|
2,023 |
C510878
|
NM
|
alkaline phosphatase 2, mouse
|
ALPL protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C510878
|
NO
|
GenBank J02980
|
RefSeq NM_001287172
|
Note updated on a SCR
|
2,023 |
C512261
|
RN
|
EC 2.7.7.49
|
EC 3.1.-
|
Registry number updated on an SCR
|
2,023 |
C512725
|
NM
|
vinexin, rat
|
Sorbs3 protein, rat
|
Preferred Term (NM) updated on an scr
|
2,023 |
C512725
|
NO
|
an adapter protein consisting of three SH3 domains, involved in signal transduction and the reorganization of actin cytoskeleton
|
an adapter protein consisting of three SH3 domains, involved in signal transduction and the reorganization of actin cytoskeleton; RefSeq NM_001005762
|
Note updated on a SCR
|
2,023 |
C512818
|
RN
|
0
|
EC 4.2.1.1
|
Registry number updated on an SCR
|
2,023 |
C513370
|
NO
|
inhibits SARS-CoV 3CL protease; structure in first source
|
inhibits SARS-CoV 3CL protease
|
Note updated on a SCR
|
2,023 |
C513486
|
NM
|
N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N1-(2-fluoro-5-methylphenyl)urea
|
linifanib
|
Preferred Term (NM) updated on an scr
|
2,023 |
C513486
|
NO
|
has antineoplastic activity; structure in first source
|
has antineoplastic activity
|
Note updated on a SCR
|
2,023 |
C513486
|
RN
|
0
|
CO93X137CW
|
Registry number updated on an SCR
|
2,023 |
C513751
|
NM
|
thallium-4-benzyl-DOTA-rituximab
|
thorium-4-benzyl-DOTA-rituximab
|
Preferred Term (NM) updated on an scr
|
2,023 |
C513894
|
NM
|
cucurbituril
|
cucurbit(n)uril
|
Preferred Term (NM) updated on an scr
|
2,023 |
C513894
|
NO
|
barrel-shaped macrocycles composed of (n) glycoluril monomers linked by methylene bridges
|
barrel-shaped macrocycles composed of (n) glycoluril monomers linked by methylene bridges; often abbreviated CB[n] or CB*[n]
|
Note updated on a SCR
|
2,023 |
C513894
|
NO
|
structure in first source
|
barrel-shaped macrocycles composed of (n) glycoluril monomers linked by methylene bridges
|
Note updated on a SCR
|
2,023 |
C513894
|
SO
|
Angew Chem Int Ed Engl. 2005 May 30;44(22):3402-7
|
Angew Chem Int Ed Engl. 2001 Nov 19;40(22):4233-4235.
|
Source updated on a SCR
|
2,023 |
C514128
|
NO
|
Myo1f-deficient mice exhibited abnormally increased adhesion and reduced motility, resulting from augmented exocytosis of beta2 integrin-containing granules; Myo1f directs immune cell motility and innate host defense against infection
|
RefSeq NM_053214
|
Note updated on a SCR
|
2,023 |
C515448
|
NM
|
leptin receptor, human
|
LEPR protein, human
|
Preferred Term (NM) updated on an scr
|
2,023 |
C516179
|
NM
|
CesA3 protein, Arabidopsis
|
At5g05170 protein, Arabidopsis
|
Preferred Term (NM) updated on an scr
|
2,023 |
C516179
|
NO
|
catalytic subunit of Arabidopsis cellulose synthase; amino acid sequence in first source
|
catalytic subunit of Arabidopsis cellulose synthase; RefSeq NM_120599
|
Note updated on a SCR
|
2,023 |
C516498
|
LT
|
LAB
|
TRD
|
Lexical type updated on a SCR
|
2,023 |
C516498
|
RN
|
0
|
814P46684U
|
Registry number updated on an SCR
|
2,023 |
C517871
|
NM
|
ppm1e protein, Zebrafish
|
ppm1e protein, zebrafish
|
Preferred Term (NM) updated on an scr
|
2,023 |
C519852
|
NM
|
Sgp130Fc protein
|
olamkicept
|
Preferred Term (NM) updated on an scr
|
2,023 |
C519852
|
RN
|
0
|
ZW1H7GZO9W
|
Registry number updated on an SCR
|
2,023 |
C520022
|
NM
|
1-(2-((1-(4-amino-3-chlorophenyl)methanoyl)amino)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxylic acid
|
belnacasan
|
Preferred Term (NM) updated on an scr
|
2,023 |
C520022
|
NO
|
an NSAID; structure in first source
|
a NSAID
|
Note updated on a SCR
|
2,023 |
C520022
|
RN
|
0
|
00OLE78529
|
Registry number updated on an SCR
|
2,023 |
C520858
|
NO
|
structure in first source; inhibitor of beta-secretase
|
inhibitor of beta-secretase
|
Note updated on a SCR
|
2,023 |
C522130
|
RN
|
0
|
W34UO2M4T6
|
Registry number updated on an SCR
|
2,023 |
C522458
|
RN
|
0
|
NM6AF3AW9M
|
Registry number updated on an SCR
|
2,023 |
C522837
|
NM
|
N-(((2-(4-(2-ethyl-4,6-dimethyl-1H-imidazo(4,5-c)pyridin-1-yl) phenyl)ethyl)amino)carbonyl)-4-methylbenzenesulfonamide
|
grapiprant
|
Preferred Term (NM) updated on an scr
|
2,023 |
C522837
|
NO
|
a potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties
|
a potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties; cyclooxygenase inhibitors
|
Note updated on a SCR
|
2,023 |
C522837
|
NO
|
a potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties; structure in first source
|
a potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties
|
Note updated on a SCR
|
2,023 |
C522837
|
RN
|
0
|
J9F5ZPH7NB
|
Registry number updated on an SCR
|
2,023 |
C523006
|
NM
|
Lin-54 protein, human
|
Lin54 protein, human
|
Preferred Term (NM) updated on an scr
|
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