Year
int64
2.02k
2.03k
UI
stringlengths
7
10
UPDATED_FIELD
stringclasses
13 values
REPLACED_VALUE
stringlengths
1
912
REPLACEMENT_VALUE
stringlengths
1
910
NOTES
stringclasses
19 values
2,023
C469610
SO
HIV Clin Trials 2002 Jul-Aug;3(4):272-8
J R Soc Health 1991 Oct;111(5):170-1
Source updated on a SCR
2,023
C469610
SO
J R Soc Health 1991 Oct;111(5):170-1
HIV Clin Trials 2002 Jul-Aug;3(4):272-8
Source updated on a SCR
2,023
C469995
NM
N-methanocarbathymidine
(north)-methanocarbathymidine
Preferred Term (NM) updated on an scr
2,023
C469995
NO
structure in first source
also called NMCT
Note updated on a SCR
2,023
C470703
NM
Nth1 protein, mouse
Nthl1 protein, mouse
Preferred Term (NM) updated on an scr
2,023
C473608
NM
daf-28 protein, C. elegans
daf-28 protein, C elegans
Preferred Term (NM) updated on an scr
2,023
C475934
NO
RN given for (3R-trans)-isomer; suppresses expression of both HBsAg and HBeAg; structure in first source
suppresses expression of both HBsAg and HBeAg
Note updated on a SCR
2,023
C477447
NO
has antineoplastic activity; structure in first source
has antineoplastic activity
Note updated on a SCR
2,023
C477447
SY
Tussafug
benproperine pamoate
Synonym updated on an scr
2,023
C479566
NM
LPP3 protein, mouse
Plpp3 protein, mouse
Preferred Term (NM) updated on an scr
2,023
C479748
NO
GenBank AJ536192
RefSeq NM_001170799
Note updated on a SCR
2,023
C479935
NO
an HIV inhibitor; structure in first source; disrupts late step in processing HIV Major Core Protein p24, preventing the capsid precursor p25 from being converted to mature capsid p24
an HIV inhibitor; disrupts late step in processing HIV Major Core Protein p24, preventing the capsid precursor p25 from being converted to mature capsid p24
Note updated on a SCR
2,023
C479935
SO
Proc Natl Acad Sci U S A 2003 Nov 11;100(23):13555-60
Retrovirology. 2004 Jun 29;1(1):15
Source updated on a SCR
2,023
C479935
SO
Retrovirology. 2004 Jun 29;1(1):15
Proc Natl Acad Sci U S A 2003 Nov 11;100(23):13555-60
Source updated on a SCR
2,023
C480040
RN
0
EC 2.3.2.27
Registry number updated on an SCR
2,023
C480499
NM
NHE protein, mouse
Slc9c1 protein, mouse
Preferred Term (NM) updated on an scr
2,023
C480499
NO
sperm-specific Na+H+ exchanger required for sperm motility and fertility; GenBank AY368685
RefSeq NM_198106
Note updated on a SCR
2,023
C482089
NM
laeverin, human
LVRN protein, human
Preferred Term (NM) updated on an scr
2,023
C482089
NO
expressed in extravillous trophoblasts, belongs to membrane-bound gluzincin metallopeptidases; has a peptidase M1 motif containing a zinc-binding active site; amino acid sequence in first source
expressed in extravillous trophoblasts, belongs to membrane-bound gluzincin metallopeptidases; has a peptidase M1 motif containing a zinc-binding active site; amino acid sequence in first source; RefSeq NM_173800
Note updated on a SCR
2,023
C483025
NM
Dfy protein, mouse
Ackr1 protein mouse
Preferred Term (NM) updated on an scr
2,023
C484810
NM
Tozasertib
tozasertib
Preferred Term (NM) updated on an scr
2,023
C484810
NO
a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth; structure in first source
a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth
Note updated on a SCR
2,023
C484876
NO
see scutellarein for aglycone; structure in first source
see scutellarein for aglycone
Note updated on a SCR
2,023
C485800
NO
from Maclura pomifera; structure in first source
from Maclura pomifera
Note updated on a SCR
2,023
C486070
NM
Tcfcp2l1 protein, mouse
Tfcp2l1 protein, mouse
Preferred Term (NM) updated on an scr
2,023
C486182
NO
an estrogen receptor modulator
a selective estrogen receptor beta agonist or modulator. also called DPN compound
Note updated on a SCR
2,023
C486182
SO
Br J Pharmacol. 2003 Aug;139(7):1249-53
Neuroendocrinology. 2004;79(5):247-58
Source updated on a SCR
2,023
C488674
RN
0
EC 2.3.2.27
Registry number updated on an SCR
2,023
C489251
RN
0
P0LE4QW0S6
Registry number updated on an SCR
2,023
C489251
SY
GW 5074
GW-5074
Synonym updated on an scr
2,023
C489897
NO
isolated from the fruit and twig of Aglaia silvestris; structure in first source
isolated from the fruit and twig of Aglaia silvestris
Note updated on a SCR
2,023
C492871
NO
a once-a-day, fixed-dose combination of Epivir and Ziagen
combination of Epivir and Ziagen
Note updated on a SCR
2,023
C493903
NO
recognized by monoclonal antibody 3H11; function unknown; GenBank AF317887; RefSeq NM_025114
recognized by monoclonal antibody 3H11; function unknown; GenBank AF317887; RefSeq NM_025114. mutation on cep290 protein gene associated with LEBER CONGENITAL AMAUROSIS 10.
Note updated on a SCR
2,023
C498826
NM
4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide
nilotinib
Preferred Term (NM) updated on an scr
2,023
C498826
NO
antineoplastic agent; structure in first source
antineoplastic agent
Note updated on a SCR
2,023
C498826
RN
0
F41401512X
Registry number updated on an SCR
2,023
C498826
SY
Tasigna
nilotinib hydrochloride hydrate
Synonym updated on an scr
2,023
C499686
NM
oxyS protein, E coli
oxyS small RNA, E coli
Preferred Term (NM) updated on an scr
2,023
C499686
NO
a small RNA regulator that negatively regulates rpoS translation and fhlA translation
a small RNA regulator that negatively regulates rpoS translation and fhlA translation; RefSeq NC_000913
Note updated on a SCR
2,023
C500926
NO
indole-ether quinazoline; vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor
vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor
Note updated on a SCR
2,023
C501326
NM
ALR-1 protein, C. elegans
ALR-1 protein, C elegans
Preferred Term (NM) updated on an scr
2,023
C501445
NM
Dlgh2 protein, mouse
Dlg2 protein, mouse
Preferred Term (NM) updated on an scr
2,023
C501445
NO
*INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS (2005-2011)
RefSeq NM_011807
Note updated on a SCR
2,023
C501451
NO
GenBank AF087696, RefSeq XM_340912
RefSeq NM_053513
Note updated on a SCR
2,023
C502014
RN
Ec 3.4.21.-
EC 3.4.21.-
Registry number updated on an SCR
2,023
C505045
NM
Tecovirimat
tecovirimat
Preferred Term (NM) updated on an scr
2,023
C505045
NO
a potent and specific inhibitor of orthopoxvirus replication
A potent and specific inhibitor of orthopoxvirus replication. It is used for the treatment of SMALLPOX and other orthopoxvirus infections, including MONKEYPOX under expanded access investigational new drug protocol (https://www.cdc.gov/poxvirus/monkeypox/clinicians/Tecovirimat.html).
Note updated on a SCR
2,023
C505045
NO
a potent and specific inhibitor of orthopoxvirus replication; structure in first source
a potent and specific inhibitor of orthopoxvirus replication
Note updated on a SCR
2,023
C505361
NO
induces apoptosis by targeting BCL2 & could be used for therapy of Bcl2-overexpressing tumors
RefSeq NR_029485 (A); RefSeq NR_029663 (B)
Note updated on a SCR
2,023
C505380
NO
structure in first source
non-immunosuppressive immunophilin ligand
Note updated on a SCR
2,023
C505380
RN
0
K0Z8830U95
Registry number updated on an SCR
2,023
C505734
NO
a TAK1 inhibitor
a TAK1 inhibitor; has anti-inflammatory activity; structure in first source
Note updated on a SCR
2,023
C505734
SO
Endocrinology 2005 Nov;146(11):4814-24
Int J Immunopharmacol 1999 Dec;21(12):799-814
Source updated on a SCR
2,023
C506426
NO
from Scutellaria baicalensis; structure in first source
from Scutellaria baicalensis
Note updated on a SCR
2,023
C507738
NM
HIM-8 protein, C. elegans
HIM-8 protein, C elegans
Preferred Term (NM) updated on an scr
2,023
C507827
NO
structure in first source
a macrocyclic polymer compound comprising 10 GLYCOLURIL units with methylene bridges
Note updated on a SCR
2,023
C507913
NM
KSRP protein, mouse
Khsrp protein, mouse
Preferred Term (NM) updated on an scr
2,023
C508040
LT
LAB
TRD
Lexical type updated on a SCR
2,023
C508066
NM
NAC2 protein, Arabidopsis
At3g15510 protein, Arabidopsis
Preferred Term (NM) updated on an scr
2,023
C508617
NM
PVF-1 protein, C. elegans
PVF-1 protein, C elegans
Preferred Term (NM) updated on an scr
2,023
C508854
NO
orally active neurokinin-1 receptor antagonist; structure in first source
orally active neurokinin-1 receptor antagonist
Note updated on a SCR
2,023
C508887
NO
a synthetic pleuromutilin; structure in first source
a synthetic pleuromutilin
Note updated on a SCR
2,023
C510728
RN
0
EC 3.6.4.12
Registry number updated on an SCR
2,023
C510763
NM
CIBZ protein, mouse
Zbtb38 protein, mouse
Preferred Term (NM) updated on an scr
2,023
C510763
NO
ortholog of ZENON protein from rat; GenBank DQ192019
ortholog of ZENON protein from rat; RefSeq NM_175537
Note updated on a SCR
2,023
C510878
NM
alkaline phosphatase 2, mouse
ALPL protein, mouse
Preferred Term (NM) updated on an scr
2,023
C510878
NO
GenBank J02980
RefSeq NM_001287172
Note updated on a SCR
2,023
C512261
RN
EC 2.7.7.49
EC 3.1.-
Registry number updated on an SCR
2,023
C512725
NM
vinexin, rat
Sorbs3 protein, rat
Preferred Term (NM) updated on an scr
2,023
C512725
NO
an adapter protein consisting of three SH3 domains, involved in signal transduction and the reorganization of actin cytoskeleton
an adapter protein consisting of three SH3 domains, involved in signal transduction and the reorganization of actin cytoskeleton; RefSeq NM_001005762
Note updated on a SCR
2,023
C512818
RN
0
EC 4.2.1.1
Registry number updated on an SCR
2,023
C513370
NO
inhibits SARS-CoV 3CL protease; structure in first source
inhibits SARS-CoV 3CL protease
Note updated on a SCR
2,023
C513486
NM
N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N1-(2-fluoro-5-methylphenyl)urea
linifanib
Preferred Term (NM) updated on an scr
2,023
C513486
NO
has antineoplastic activity; structure in first source
has antineoplastic activity
Note updated on a SCR
2,023
C513486
RN
0
CO93X137CW
Registry number updated on an SCR
2,023
C513751
NM
thallium-4-benzyl-DOTA-rituximab
thorium-4-benzyl-DOTA-rituximab
Preferred Term (NM) updated on an scr
2,023
C513894
NM
cucurbituril
cucurbit(n)uril
Preferred Term (NM) updated on an scr
2,023
C513894
NO
barrel-shaped macrocycles composed of (n) glycoluril monomers linked by methylene bridges
barrel-shaped macrocycles composed of (n) glycoluril monomers linked by methylene bridges; often abbreviated CB[n] or CB*[n]
Note updated on a SCR
2,023
C513894
NO
structure in first source
barrel-shaped macrocycles composed of (n) glycoluril monomers linked by methylene bridges
Note updated on a SCR
2,023
C513894
SO
Angew Chem Int Ed Engl. 2005 May 30;44(22):3402-7
Angew Chem Int Ed Engl. 2001 Nov 19;40(22):4233-4235.
Source updated on a SCR
2,023
C514128
NO
Myo1f-deficient mice exhibited abnormally increased adhesion and reduced motility, resulting from augmented exocytosis of beta2 integrin-containing granules; Myo1f directs immune cell motility and innate host defense against infection
RefSeq NM_053214
Note updated on a SCR
2,023
C515448
NM
leptin receptor, human
LEPR protein, human
Preferred Term (NM) updated on an scr
2,023
C516179
NM
CesA3 protein, Arabidopsis
At5g05170 protein, Arabidopsis
Preferred Term (NM) updated on an scr
2,023
C516179
NO
catalytic subunit of Arabidopsis cellulose synthase; amino acid sequence in first source
catalytic subunit of Arabidopsis cellulose synthase; RefSeq NM_120599
Note updated on a SCR
2,023
C516498
LT
LAB
TRD
Lexical type updated on a SCR
2,023
C516498
RN
0
814P46684U
Registry number updated on an SCR
2,023
C517871
NM
ppm1e protein, Zebrafish
ppm1e protein, zebrafish
Preferred Term (NM) updated on an scr
2,023
C519852
NM
Sgp130Fc protein
olamkicept
Preferred Term (NM) updated on an scr
2,023
C519852
RN
0
ZW1H7GZO9W
Registry number updated on an SCR
2,023
C520022
NM
1-(2-((1-(4-amino-3-chlorophenyl)methanoyl)amino)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxylic acid
belnacasan
Preferred Term (NM) updated on an scr
2,023
C520022
NO
an NSAID; structure in first source
a NSAID
Note updated on a SCR
2,023
C520022
RN
0
00OLE78529
Registry number updated on an SCR
2,023
C520858
NO
structure in first source; inhibitor of beta-secretase
inhibitor of beta-secretase
Note updated on a SCR
2,023
C522130
RN
0
W34UO2M4T6
Registry number updated on an SCR
2,023
C522458
RN
0
NM6AF3AW9M
Registry number updated on an SCR
2,023
C522837
NM
N-(((2-(4-(2-ethyl-4,6-dimethyl-1H-imidazo(4,5-c)pyridin-1-yl) phenyl)ethyl)amino)carbonyl)-4-methylbenzenesulfonamide
grapiprant
Preferred Term (NM) updated on an scr
2,023
C522837
NO
a potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties
a potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties; cyclooxygenase inhibitors
Note updated on a SCR
2,023
C522837
NO
a potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties; structure in first source
a potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties
Note updated on a SCR
2,023
C522837
RN
0
J9F5ZPH7NB
Registry number updated on an SCR
2,023
C523006
NM
Lin-54 protein, human
Lin54 protein, human
Preferred Term (NM) updated on an scr