Year
int64 2.02k
2.03k
| UI
stringlengths 7
10
| UPDATED_FIELD
stringclasses 13
values | REPLACED_VALUE
stringlengths 1
912
| REPLACEMENT_VALUE
stringlengths 1
910
| NOTES
stringclasses 19
values |
---|---|---|---|---|---|
2,023 |
D000084602
|
MS
|
A collection of the SYMPATHETIC NERVOUS SYSTEM and the ADRENAL MEDULLA of the ADRENAL GLANDS. Intra-adrenal connection from the medulla to the cortex connects the system to other neuroendocrine systems, which in concert participate in FLIGHT REACTION in stress situations. CATECHOLAMINES are the principle hormone in the system.
|
A connection of the SYMPATHETIC NERVOUS SYSTEM and the ADRENAL MEDULLA of the ADRENAL GLANDS. Intra-adrenal connection from the medulla to the cortex connects the system to other neuroendocrine systems, which in concert participate in FLIGHT REACTION in stress situations. CATECHOLAMINES are the principle hormone in the system.
|
MeSH scope note updated on a descriptor
|
2,023 |
D000086882
|
MS
|
Papain-like proteases that occur in species of CORONAVIRIDAE. Some species have more than one papain-like protease gene.
|
Papain-like proteases that occur in species of CORONAVIRIDAE. Some species have more than one papain-like protease gene.
|
MeSH scope note updated on a descriptor
|
2,023 |
D000087443
|
MS
|
A super-family of non-enzymatic proteins found in ELAPIDAE VENOMES. They possess a unique tertiary structure resembling a hand with three fingers and have diverse biological activities due to sequence and structural variations; some are ALPHA-NEUROTOXINS that bind NICOTINIC ACETYLCHOLINE RECEPTORS.
|
A super-family of non-enzymatic proteins found in ELAPIDAE VENOMS. They possess a unique tertiary structure resembling a hand with three fingers and have diverse biological activities due to sequence and structural variations; some are ALPHA-NEUROTOXINS that bind NICOTINIC ACETYLCHOLINE RECEPTORS.
|
MeSH scope note updated on a descriptor
|
2,023 |
D000087523
|
MS
|
Reduced capacity to respond to subsequent ENDOTOXIN challenges after an initial exposure. It is characterized by reduced responsiveness of INNATE IMMUNE RESPONSES, a shift from pro- to anti-inflammatory cell phenotype and impaired ANITGEN PRESENTATION.
|
Reduced capacity to respond to subsequent ENDOTOXIN challenges after an initial exposure. It is characterized by reduced responsiveness of INNATE IMMUNE RESPONSES, a shift from pro- to anti-inflammatory cell phenotype and impaired ANTIGEN PRESENTATION.
|
MeSH scope note updated on a descriptor
|
2,023 |
D000088642
|
MS
|
Persons 90 years of age and older.
|
Persons between 90 and 99 years old.
|
MeSH scope note updated on a descriptor
|
2,023 |
D000089382
|
MS
|
Extent to which HEMOGLOBIN is saturated with OXYGEN typically as measured in arterial blood. It can be measured by various methods (e.g., PULSE OXYMETER, blood gas analysis). A low blood oxygen saturation level indicates a condition called HYPOXEMIA.
|
Extent to which HEMOGLOBIN is saturated with OXYGEN typically as measured in arterial blood. It can be measured by various methods (e.g., PULSE OXYMETER, blood gas analysis). A low blood oxygen saturation level indicates a condition called HYPOXEMIA.
|
MeSH scope note updated on a descriptor
|
2,023 |
D000089582
|
MS
|
Substances consist of different components, e.g. aluminum salts, EMULSIONS such as MF59 and AS03, Toll-like receptor (TLR) agonist or combinations of IMMUNOPOTENTIATORS (QS-21 and MPL in AS01), that helps increase the magnitude of an ADAPTIVE IMMUNE RESPONSE to a VACCINE.
|
Substances consisting of different components, e.g. aluminum salts, EMULSIONS such as MF59 and AS03, Toll-like receptor (TLR) agonist or combinations of IMMUNOPOTENTIATORS (QS-21 and MPL in AS01), that helps increase the magnitude of an ADAPTIVE IMMUNE RESPONSE to a VACCINE.
|
MeSH scope note updated on a descriptor
|
2,023 |
D000090263
|
MS
|
A protein with a three-dimensional structure that forms an alpha/beta horseshoe fold. It is found in a large number of proteins with diverse functions, including INNATE IMMUNITY RESPONSE and NERVOUS SYSTEM.
|
A protein with a three-dimensional structure that forms an alpha/beta horseshoe fold. It is found in a large number of proteins with diverse functions, including in INNATE IMMUNITY RESPONSE and NERVOUS SYSTEM.
|
MeSH scope note updated on a descriptor
|
2,023 |
D000090502
|
MS
|
An adaptive mechanism used by microbes to avoid detection by the host or adapt to changes in environment by randomly and rapidly switch on and off of a gene by various mechanisms. between on and off phases. For instance, drug tolerant MYCOBACTERIUM TUBERCULOSIS arises though rapid reversible mutations in the glpK gene through phase variation.
|
An adaptive mechanism used by microbes to avoid detection by the host or adapt to changes in environment by randomly and rapidly switch on and off of a gene by various mechanisms between on and off phases. For instance, drug tolerant MYCOBACTERIUM TUBERCULOSIS arises through rapid reversible mutations in the glpK gene through phase variation.
|
MeSH scope note updated on a descriptor
|
2,023 |
D000090982
|
RN
|
N38TVC63NU
|
0
|
Registry number updated on a descriptor
|
2,023 |
D000090983
|
LT
|
NON
|
TRD
|
Lexical type updated on a descriptor
|
2,023 |
D000090984
|
RN
|
0
|
JT2NS6183B
|
Registry number updated on a descriptor
|
2,023 |
D000091202
|
MH
|
Health Disparity, Minority and Vulnerable Populations
|
Health Disparate, Minority and Vulnerable Populations
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D000091346
|
MS
|
Lysosomal Serine proteases that release N-terminal tripeptide from a polypeptide and cleave peptides between hydrophobic residues. An enzyme that in humans encoded by the TPP1 gene. It is involved in the degradation of bone collagen. Mutations in this gene are associated with the CEROID LIPOFUSCINOSIS, NEURONAL, 2; and SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVECEROID LIPOFUSCINOSIS, NEURONAL, 2; AND SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 7.
|
Lysosomal Serine proteases that release N-terminal tripeptide from a polypeptide and cleave peptides between hydrophobic residues. An enzyme that in humans encoded by the TPP1 gene. It is involved in the degradation of bone collagen. Mutations in this gene are associated with the CEROID LIPOFUSCINOSIS, NEURONAL, 2; and SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE CEROID LIPOFUSCINOSIS, NEURONAL, 2; AND SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 7.
|
MeSH scope note updated on a descriptor
|
2,023 |
D000671
|
MH
|
Amputation
|
Amputation, Surgical
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D000784
|
MH
|
Aneurysm, Dissecting
|
Aortic Dissection
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D001213
|
MH
|
Asian Americans
|
Asian
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D001741
|
LT
|
HIST
|
NON
|
Lexical type updated on a descriptor
|
2,023 |
D001741
|
LT
|
NON
|
HIST
|
Lexical type updated on a descriptor
|
2,023 |
D001741
|
MH
|
African Americans
|
Black or African American
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D002586
|
MS
|
A member of the alkali metals. It has an atomic symbol Cs, atomic number 50, and atomic weight 132.91. Cesium has many industrial applications, including the construction of atomic clocks based on its atomic vibrational frequency.
|
A member of the alkali metals. It has an atomic symbol Cs, atomic number 55, and atomic weight 132.91. Cesium has many industrial applications, including the construction of atomic clocks based on its atomic vibrational frequency.
|
MeSH scope note updated on a descriptor
|
2,023 |
D003906
|
LT
|
NON
|
ABB
|
Lexical type updated on a descriptor
|
2,023 |
D004930
|
HN
|
2023; use ESKIMOS 1965-2003, INUITS 2004-2023
|
2023; use ESKIMOS 1965-2003, INUITS 2004-2022
|
History note updated on a descriptor
|
2,023 |
D004930
|
MH
|
Inuits
|
Inuit
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D004930
|
PM
|
2023; see ESKIMOS 1965-2003, INUITS 2004-2023
|
2023; see ESKIMOS 1965-2003, INUITS 2004-2022
|
public MeSH note updated on a descriptor
|
2,023 |
D005202
|
MH
|
Far East
|
Asia, Eastern
|
Preferred Term (MH) updated on a geographic type
|
2,023 |
D006442
|
MH
|
Glycated Hemoglobin A
|
Glycated Hemoglobin
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D006476
|
MH
|
Hantavirus
|
Orthohantavirus
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D006703
|
MH
|
Homeless Persons
|
Ill-Housed Persons
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D007780
|
MH
|
Lactobacillus casei
|
Lacticaseibacillus casei
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D007780
|
PM
|
2023; see Lactobacillus casei 1974-2022
|
2023; see Lacticaseibacillus casei 1974-2022
|
public MeSH note updated on a descriptor
|
2,023 |
D008342
|
MS
|
A hereditary disorder occurring in two forms: the complete form (Franceschetti's syndrome) is characterized by antimongoloid slant of the palpebral fissures, COLOBOMA of the lower lid, MICROGNATHIA and hypoplasia of the ZYGOMATIC ARCHES, and CONGENITAL MICROTIA. It is transmitted as an autosomal trait. The incomplete form (Treacher Collins syndrome) is characterized by the same anomalies in less pronounced degree. It occurs sporadically, but an autosomal dominant mode of transmission is suspected. (Dorland, 27th ed)
|
A hereditary disorder occurring in two forms: the complete form (Franceschetti's syndrome) is characterized by a slant of the palpebral fissures, COLOBOMA of the lower lid, MICROGNATHIA and hypoplasia of the ZYGOMATIC ARCHES, and CONGENITAL MICROTIA. It is transmitted as an autosomal trait. The incomplete form (Treacher Collins syndrome) is characterized by the same anomalies in less pronounced degree. It occurs sporadically, but an autosomal dominant mode of transmission is suspected. (Dorland, 27th ed)
|
MeSH scope note updated on a descriptor
|
2,023 |
D012900
|
MS
|
A live VACCINIA VIRUS vaccine of calf lymph or chick embryo origin, used for immunization against smallpox. It is now recommended only for laboratory workers exposed to smallpox virus. Certain countries continue to vaccinate those in the military service. Complications that result from smallpox vaccination include vaccinia, secondary bacterial infections, and encephalomyelitis. (Dorland, 28th ed)
|
A VACCINIA VIRUS vaccine used for immunization against SMALLPOX. It is now recommended only for laboratory workers exposed to SMALLPOX VIRUS. Certain countries continue to vaccinate those in the military service. Rare complications most often associated with older generation smallpox vaccines include VACCINIA, secondary bacterial infections, and ENCEPHALOMYELITIS. Because MONKEYPOX VIRUS and SMALLPOX VIRUS are both ORTHOPOXVIRUS and are closely related smallpox vaccines provide effective CROSS-PROTECTION against MONKEYPOX (https://www.cdc.gov/poxvirus/monkeypox/clinicians/smallpox-vaccine.html).
|
MeSH scope note updated on a descriptor
|
2,023 |
D017367
|
MH
|
Serotonin Uptake Inhibitors
|
Selective Serotonin Reuptake Inhibitors
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D017394
|
MH
|
RNA, Guide
|
RNA, Guide, Kinetoplastida
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D017406
|
MS
|
A form of discrimination in the workplace which violates the Civil Rights Act of 1964. Offensive sexual conduct may include unwelcome advances, comments, touching, questions about marital status and sex practices, etc. Both men and women may be aggressors or victims. (Slee and Slee, Health Care Terms, 2d ed, p.404). While civil rights legislation deals with sexual harassment in the workplace, the behavior is not restricted to this; it may take place outside the work environment: in schools and colleges, athletics, and other social milieus and activities.
|
A form of discrimination in the workplace which violates the Civil Rights Act of 1964. Offensive sexual conduct may include unwelcome advances, comments, touching, questions about marital status and sex practices, etc. Both men and women may be aggressors or victims. (Slee and Slee, Health Care Terms, 2d ed, p.404). While civil rights legislation deals with sexual harassment in the workplace, the behavior is not restricted to this; it may take place outside the work environment: in schools, athletics, and other social milieus and activities.
|
MeSH scope note updated on a descriptor
|
2,023 |
D018551
|
MH
|
Lycopersicon esculentum
|
Solanum lycopersicum
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D019066
|
MS
|
The appearance of the face that is often characteristic of a disease or pathological condition, as the elfin facies of WILLIAMS SYNDROME or the mongoloid facies of DOWN SYNDROME. (Random House Unabridged Dictionary, 2d ed)
|
The appearance of the face that is often characteristic of a disease or pathological condition, as the elfin facies of WILLIAMS SYNDROME or facies of DOWN SYNDROME. (Random House Unabridged Dictionary, 2d ed)
|
MeSH scope note updated on a descriptor
|
2,023 |
D019651
|
MH
|
Reconstructive Surgical Procedures
|
Plastic Surgery Procedures
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D020935
|
MS
|
An intracellular signaling system involving the MAP kinase cascades (three-membered protein kinase cascades). Various upstream activators, which act in response to extracellular stimuli, trigger the cascades by activating the first member of a cascade, MAP KINASE KINASE KINASES; (MAPKKKs). Activated MAPKKKs phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES which in turn phosphorylate the MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs). The MAPKs then act on various downstream targets to affect gene expression. In mammals, there are several distinct MAP kinase pathways including the ERK (extracellular signal-regulated kinase) pathway, the SAPK/JNK (stress-activated protein kinase/c-jun kinase) pathway, and the p38 kinase pathway. There is some sharing of components among the pathways depending on which stimulus originates activation of the cascade.
|
An intracellular signaling system involving the mitogen-activated protein kinase cascades (three-membered protein kinase cascades). Various upstream activators, which act in response to extracellular stimuli, trigger the cascades by activating the first member of a cascade, MAP KINASE KINASE KINASES; (MAPKKKs). Activated MAPKKKs phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES which in turn phosphorylate the MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs). The MAPKs then act on various downstream targets to affect gene expression. In mammals, there are several distinct MAP kinase pathways including the ERK (extracellular signal-regulated kinase) pathway, the SAPK/JNK (stress-activated protein kinase/c-jun kinase) pathway, and the p38 kinase pathway. There is some sharing of components among the pathways depending on which stimulus originates activation of the cascade.
|
MeSH scope note updated on a descriptor
|
2,023 |
D044383
|
MH
|
Blacks
|
Black People
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D044465
|
MH
|
Whites
|
White People
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D044466
|
MH
|
Asians
|
Asian People
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D044467
|
MH
|
American Native Continental Ancestry Group
|
American Indian or Alaska Native
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D044468
|
PM
|
2022; for ABORIGINES, AUSTRALIAN see OCEANIC ANCESTRY GROUP 2006-; see ABORIGINES 1991-2003; for AUSTRALOID RACE see AUSTRALOID RACE 1978-2003, see AUSTRALIAN RACE 1963-1977, see OCEANIC ANCESTRY GROUP 2004-2021
|
2022
|
public MeSH note updated on a descriptor
|
2,023 |
D045473
|
MH
|
SARS Virus
|
Severe acute respiratory syndrome-related coronavirus
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D052196
|
HN
|
2023; was LACTOBACILLUS BREVIS 2006-2022
|
2023(2006)
|
History note updated on a descriptor
|
2,023 |
D052196
|
MH
|
Lactobacillus brevis
|
Levilactobacillus brevis
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D052197
|
MH
|
Lactobacillus fermentum
|
Limosilactobacillus fermentum
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D052200
|
MH
|
Lactobacillus reuteri
|
Limosilactobacillus reuteri
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D052200
|
PM
|
2023(2006)
|
2023; see LACTOBACILLUS REUTERI 2006-2022
|
public MeSH note updated on a descriptor
|
2,023 |
D052201
|
MH
|
Lactobacillus rhamnosus
|
Lacticaseibacillus rhamnosus
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D052201
|
PM
|
2023(2006)
|
2023; see LACTOBACILLUS RHAMNOSUS 2006-2022
|
public MeSH note updated on a descriptor
|
2,023 |
D055964
|
HN
|
2023; use AILIEN HAND SYNDROME 2010-2022
|
2023(2010)
|
History note updated on a descriptor
|
2,023 |
D055964
|
MH
|
Alien Hand Syndrome
|
Alien Limb Phenomenon
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D055964
|
PM
|
2023; see AILIEN HAND SYNDROME 2010-2022
|
2023; see ALIEN HAND SYNDROME 2010-2022
|
public MeSH note updated on a descriptor
|
2,023 |
D062065
|
MH
|
Waste Water
|
Wastewater
|
Preferred Term (MH) updated on a descriptor
|
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.