Year
int64 2.02k
2.03k
| UI
stringlengths 7
10
| UPDATED_FIELD
stringclasses 13
values | REPLACED_VALUE
stringlengths 1
912
| REPLACEMENT_VALUE
stringlengths 1
910
| NOTES
stringclasses 19
values |
---|---|---|---|---|---|
2,023 |
C523798
|
NM
|
1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho(2,3-d)imidazolium
|
sepantronium
|
Preferred Term (NM) updated on an scr
|
2,023 |
C523798
|
NO
|
a survivin suppressant with antineoplastic activity; structure in first source
|
a survivin suppressant with antineoplastic activity
|
Note updated on a SCR
|
2,023 |
C523802
|
NO
|
structure in first source
|
a macrocyclic polymer compound comprising 5 GLYCOLURIL units with methylene bridges
|
Note updated on a SCR
|
2,023 |
C524407
|
NM
|
alpha-gustducin, mouse
|
GNAT3 protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C524407
|
NO
|
regulates secretion of glucagon-like peptide-1; a taste G protein; GenBank AC129572
|
RefSeq NM_001081143
|
Note updated on a SCR
|
2,023 |
C524761
|
NM
|
leucine carboxyl methyltransferase-1, human
|
LCMT1 protein, human
|
Preferred Term (NM) updated on an scr
|
2,023 |
C524761
|
NO
|
necessary for normal progression through mitosis in mammalian cells; RefSeq NM_001032391.1; NP_001027563.1
|
necessary for normal progression through mitosis in mammalian cells; RefSeq NM_016309
|
Note updated on a SCR
|
2,023 |
C525638
|
NM
|
Hbo1 protein, mouse
|
Kat7 protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C525638
|
NO
|
a subunit of both JADE and ING; required for H4 acetylation; GenBank BC048904
|
a subunit of both JADE and ING; required for H4 acetylation; RefSeq NM_001195003
|
Note updated on a SCR
|
2,023 |
C526014
|
NO
|
GenBank AC118592
|
RefSeq NM_001081424
|
Note updated on a SCR
|
2,023 |
C526276
|
NO
|
GenBank AK027784
|
RefSeq NM_023915
|
Note updated on a SCR
|
2,023 |
C526464
|
NM
|
diacylglycerol kinase epsilon, human
|
DGKE protein, human
|
Preferred Term (NM) updated on an scr
|
2,023 |
C528327
|
NM
|
Fedratinib
|
fedratinib
|
Preferred Term (NM) updated on an scr
|
2,023 |
C529380
|
NM
|
sestrin 2 protein, mouse
|
Sesn2 protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C529873
|
NO
|
influences nuclear envelope morphology; has been sequenced
|
RefSeq NM_001183919.1
|
Note updated on a SCR
|
2,023 |
C531059
|
NM
|
sestrin 1 protein, mouse
|
Sesn1 protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C531059
|
NO
|
GenBank BC055753
|
RefSeq NM_001162908
|
Note updated on a SCR
|
2,023 |
C531360
|
NM
|
SRp75 protein, mouse
|
Srsf4 protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C531360
|
NO
|
GenBank AK075769
|
RefSeq NM_001369308
|
Note updated on a SCR
|
2,023 |
C532667
|
NM
|
MURC protein, mouse
|
Cavin4 protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C534481
|
RN
|
0
|
EC 2.3.2.27
|
Registry number updated on an SCR
|
2,023 |
C535877
|
NO
|
Broad terminal phalanges of the thumbs and great toes, antimongoloid slant of the palpebral fissures, and characteristic beaked noses
|
Broad terminal phalanges of the thumbs and great toes, a slant of the palpebral fissures, and characteristic beaked noses
|
Note updated on a SCR
|
2,023 |
C536281
|
NM
|
Idiopathic pulmonary hemosiderosis
|
idiopathic pulmonary hemosiderosis
|
Preferred Term (NM) updated on an scr
|
2,023 |
C536281
|
NO
|
A rare disorder characterized by the triad of HEMOPTYSIS, IRON-DEFICIENCY ANEMIA, and transient pulmonary infiltrates observed by RADIOGRAPHY. The underlying disease mechanism is a propensity to recurrent intrapulmonary hemorrhage. Even though large amounts of iron are laid down in the lung, with normal or increased total body iron, anemia occurs because of inability of the erythron to use iron sequestered in pulmonary MACROPHAGES. RESPIRATORY INSUFFICENCY may result from PULMONARY FIBROSIS in advanced cases. OMIM: 178550
|
A rare disorder characterized by the triad of HEMOPTYSIS; IRON-DEFICIENCY ANEMIA, and diffuse pulmonary hemorrhage as seen as transient pulmonary infiltrates on RADIOGRAPHY. The underlying disease mechanism is a propensity to recurrent intrapulmonary hemorrhage. Even though large amounts of iron are laid down in the lung, with normal or increased total body iron, anemia occurs because of inability of the erythron to use iron sequestered in pulmonary MACROPHAGES. RESPIRATORY INSUFFICIENCY may result from PULMONARY FIBROSIS in advanced cases. OMIM: 178550
|
Note updated on a SCR
|
2,023 |
C536281
|
SY
|
Alveolar hypoventilation syndrome
|
alveolar hypoventilation syndrome
|
Synonym updated on an scr
|
2,023 |
C537118
|
NO
|
Short stature, mongoloid facies, short spadelike hands, broad thumbs, genu recurvatum, thick palmar and forearm fasciae, shuffling short-stepped gait
|
Short stature, facies, short spadelike hands, broad thumbs, genu recurvatum, thick palmar and forearm fasciae, shuffling short-stepped gait
|
Note updated on a SCR
|
2,023 |
C540817
|
NO
|
used to treat chronic obstructive pulmonary disease
|
used to treat chronic obstructive pulmonary disease; combined extracts of Scutellaria baicalensis Georgi, Lonicera japonica flos, Fructus Forsythiae, Pulvis Fellis Ursi and Cornu Saigae Tataricae. Major compounds are Baicalein, ursodeoxycholic acid, chenodeoxycholic acid, forsythin and chlorogenic acid
|
Note updated on a SCR
|
2,023 |
C540817
|
SO
|
Zhongguo Zhong Yao Za Zhi 2009 Jan;34(1):104-6
|
J Ethnopharmacol . 2011 Mar 8;134(1):165-70.
|
Source updated on a SCR
|
2,023 |
C540933
|
NO
|
putative biomarker for head and neck squamous cell carcinoma; has been sequenced
|
RefSeq NR_029867
|
Note updated on a SCR
|
2,023 |
C541037
|
NM
|
PogZ protein, human
|
POGZ protein, human
|
Preferred Term (NM) updated on an scr
|
2,023 |
C541037
|
NO
|
GenBank AB007930
|
RefSeq NM_207171
|
Note updated on a SCR
|
2,023 |
C541037
|
RN
|
EC 2.7.7.-
|
0
|
Registry number updated on an SCR
|
2,023 |
C541529
|
NO
|
isolated from Glycyrrhiza inflata; inhibits phosphorylation of NF-kappaB p65 in LPS signaling pathway; structure in first source
|
isolated from Glycyrrhiza inflata; inhibits phosphorylation of NF-kappaB p65 in LPS signaling pathway
|
Note updated on a SCR
|
2,023 |
C541689
|
NM
|
Puf-A protein, mouse
|
Pum3 protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C541689
|
NO
|
has been sequenced
|
RefSeq NM_177474
|
Note updated on a SCR
|
2,023 |
C542157
|
NM
|
phospholipase D3, mouse
|
Pld3 protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C542157
|
NO
|
GenBank AF026124
|
RefSeq NM_001317355
|
Note updated on a SCR
|
2,023 |
C543351
|
NO
|
RefSeq NW_923574.1; NT_007933.15
|
RefSeq NR_029498
|
Note updated on a SCR
|
2,023 |
C545185
|
RN
|
0
|
KK8645V7LE
|
Registry number updated on an SCR
|
2,023 |
C546275
|
NM
|
MIRN513 microRNA, human
|
MIRN513A1 microRNA, human
|
Preferred Term (NM) updated on an scr
|
2,023 |
C548820
|
NM
|
kalirin protein, mouse
|
KALRN protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C548820
|
NO
|
GenBank BC157950
|
RefSeq XM_011245951
|
Note updated on a SCR
|
2,023 |
C549101
|
NM
|
SESN3 protein, mouse
|
Sesn3 protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C550357
|
NM
|
6-cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-(1,2,4)triazolo(1,5-a)pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one
|
filibuvir
|
Preferred Term (NM) updated on an scr
|
2,023 |
C550357
|
NO
|
inhibits HCV RNA replicase; structure in first source
|
inhibits HCV RNA replicase
|
Note updated on a SCR
|
2,023 |
C552705
|
NO
|
an adrenergic beta2 receptor agonist; structure in first source
|
an adrenergic beta2 receptor agonist
|
Note updated on a SCR
|
2,023 |
C552705
|
RN
|
0
|
ZH5SMU97AJ
|
Registry number updated on an SCR
|
2,023 |
C552705
|
SY
|
PF 610355
|
PF-00610355
|
Synonym updated on an scr
|
2,023 |
C553360
|
NO
|
an antineoplastic agent and tyrosine kinase inhibitor; structure in first source
|
an antineoplastic agent and tyrosine kinase inhibitor
|
Note updated on a SCR
|
2,023 |
C553360
|
SY
|
HH-GV-678
|
HH-GV678
|
Synonym updated on an scr
|
2,023 |
C555691
|
NM
|
ANAC089 protein, Arabidopsis
|
AT5G22290 protein, Arabidopsis
|
Preferred Term (NM) updated on an scr
|
2,023 |
C556917
|
NO
|
structure in first source; a beta-secretase inhibitor
|
a beta-secretase inhibitor
|
Note updated on a SCR
|
2,023 |
C557933
|
NM
|
AMG 837
|
AMG-837
|
Preferred Term (NM) updated on an scr
|
2,023 |
C557933
|
NO
|
GPR40 agonist; structure in first source
|
GPR40 agonist
|
Note updated on a SCR
|
2,023 |
C557933
|
RN
|
0
|
NE6U6R66U4
|
Registry number updated on an SCR
|
2,023 |
C558424
|
NM
|
UGA1 protein, S. cerevisiae
|
UGA1 protein, S cerevisiae
|
Preferred Term (NM) updated on an scr
|
2,023 |
C567958
|
NM
|
pinkbar protein, mouse
|
Baiap2l2 protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C567958
|
NO
|
an I-BAR domain-containing protein expressed in intestinal epithelial cells
|
an I-BAR domain-containing protein expressed in intestinal epithelial cells; RefSeq NM_177580
|
Note updated on a SCR
|
2,023 |
C568792
|
NM
|
spingosine-1-phosphate receptor 4, mouse
|
sphingosine-1-phosphate receptor 4, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C569389
|
NM
|
MIRN195 microRNA, mouse
|
MIRN195a microRNA, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C569762
|
NM
|
PF 03715455
|
N-(1-(3-chloro-4-hydroxyphenyl)-3-(1,1-dimethylethyl)-1H-pyrazol-5-yl)-N'-((2-((3-(2-((2-hydroxyethyl)thio)phenyl)-1,2,4-triazolo(4,3-a)pyridin-6-yl)thio)phenyl)methyl)-urea
|
Preferred Term (NM) updated on an scr
|
2,023 |
C569762
|
RN
|
0
|
0TJ631J0KP
|
Registry number updated on an SCR
|
2,023 |
C570847
|
NM
|
ligand of Numb protein X2, human
|
Lnx2 protein, human
|
Preferred Term (NM) updated on an scr
|
2,023 |
C570847
|
NO
|
GenBank BC036755
|
RefSeq NM_153371
|
Note updated on a SCR
|
2,023 |
C571179
|
NO
|
has antibacterial activity; structure in first source
|
has antibacterial activity
|
Note updated on a SCR
|
2,023 |
C571179
|
SY
|
xerava
|
Xerava
|
Synonym updated on an scr
|
2,023 |
C571890
|
NO
|
a non-structural protein 5B polymerase inhibitor; structure in first source
|
a non-structural protein 5B polymerase inhibitor
|
Note updated on a SCR
|
2,023 |
C572449
|
NO
|
an mTOR inhibitor; structure in first source
|
an mTOR inhibitor
|
Note updated on a SCR
|
2,023 |
C572689
|
NM
|
CAMTA3 protein, Arabidopsis
|
AT2G22300 protein, Arabidopsis
|
Preferred Term (NM) updated on an scr
|
2,023 |
C573268
|
NM
|
glomalin, Mycorrhizae
|
glomalin
|
Preferred Term (NM) updated on an scr
|
2,023 |
C573580
|
NO
|
inhibits microglial activation and improves outcome after central nervous system injury in adult mice
|
glucosylceramide synthase (GCS) inhibitor
|
Note updated on a SCR
|
2,023 |
C573580
|
RN
|
0
|
CY416F5NSK
|
Registry number updated on an SCR
|
2,023 |
C574123
|
NO
|
pregnane X receptor/PXR activator; structure in first source
|
pregnane X receptor/PXR activator
|
Note updated on a SCR
|
2,023 |
C574123
|
RN
|
0
|
7CC5CL28DK
|
Registry number updated on an SCR
|
2,023 |
C575263
|
RN
|
0
|
CCP2U6LWTP
|
Registry number updated on an SCR
|
2,023 |
C576790
|
NO
|
inner nuclear membrane protein
|
RefSeq NM_001020342.2
|
Note updated on a SCR
|
2,023 |
C578009
|
NO
|
has antiviral activity
|
has antiviral activity; component of Zepatier
|
Note updated on a SCR
|
2,023 |
C578454
|
NO
|
RefSeq XM_574558
|
RefSeq XM_039094638
|
Note updated on a SCR
|
2,023 |
C578787
|
NO
|
a deubiquitinase
|
RefSeq NM_001025613
|
Note updated on a SCR
|
2,023 |
C578787
|
RN
|
EC 3.4.-
|
EC 3.4.19.12
|
Registry number updated on an SCR
|
2,023 |
C579813
|
NM
|
3-((1H-pyrazolo(3,4-b)pyridin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
|
olverembatinib
|
Preferred Term (NM) updated on an scr
|
2,023 |
C579813
|
NO
|
inhibits Bcr-Abl kinase to overcome imatinb resistance; structure in first source
|
inhibits Bcr-Abl kinase to overcome imatinb resistance
|
Note updated on a SCR
|
2,023 |
C579813
|
RN
|
0
|
KV1M7Q3CBP
|
Registry number updated on an SCR
|
2,023 |
C580661
|
NM
|
RabE1c protein, Arabidopsis
|
AT3G46060 protein, Arabidopsis
|
Preferred Term (NM) updated on an scr
|
2,023 |
C582345
|
NO
|
in phase I clinical trials for treatment of systemic sclerosis; directed against type I IFN-alpha receptor
|
directed against type I IFN-alpha receptor
|
Note updated on a SCR
|
2,023 |
C582883
|
RN
|
Ec 1.-
|
EC 1.-
|
Registry number updated on an SCR
|
2,023 |
C583533
|
NM
|
Lerepo4 protein, human
|
ZC3H15 protein, human
|
Preferred Term (NM) updated on an scr
|
2,023 |
C583620
|
NO
|
Steap4 - Six-transmembrane Epithelial Antigen of the Prostate 4; a ferri/cuprireductase; GenBank BC097353
|
RefSeq NM_001044265
|
Note updated on a SCR
|
2,023 |
C586092
|
NM
|
phospholipase D3, human
|
PLD3 protein, human
|
Preferred Term (NM) updated on an scr
|
2,023 |
C587926
|
NM
|
Gm129 protein, mouse
|
Ciart protein, mouse
|
Preferred Term (NM) updated on an scr
|
2,023 |
C588365
|
NM
|
BARK1 protein, Arabidopsis
|
AT3g23750 protein, Arabidopsis
|
Preferred Term (NM) updated on an scr
|
2,023 |
D000069980
|
MH
|
Lactobacillus paracasei
|
Lacticaseibacillus paracasei
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D000069996
|
HN
|
2023; use LACTOBACILLUS SALIVARIUS 2017-2022
|
2023(2017)
|
History note updated on a descriptor
|
2,023 |
D000069996
|
MH
|
Lactobacillus salivarius
|
Ligilactobacillus salivarius
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D000069996
|
PM
|
2023(2017)
|
2023; see LACTOBACILLUS SALIVARIUS 2017-2022
|
public MeSH note updated on a descriptor
|
2,023 |
D000070256
|
HN
|
2023; was LACTOBACILLUS SAKEI 2017-2022
|
2023(2017)
|
History note updated on a descriptor
|
2,023 |
D000070256
|
MH
|
Lactobacillus sakei
|
Latilactobacillus sakei
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D000070256
|
PM
|
2023; was LACTOBACILLUS SAKEI 2017-2022
|
2023; see LACTOBACILLUS SAKEI 2017-2022
|
public MeSH note updated on a descriptor
|
2,023 |
D000070380
|
MH
|
Xanthorrhoeaceae
|
Asphodelaceae
|
Preferred Term (MH) updated on a descriptor
|
2,023 |
D000073359
|
MH
|
Whole Exome Sequencing
|
Exome Sequencing
|
Preferred Term (MH) updated on a descriptor
|
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