Year
int64
2.02k
2.03k
UI
stringlengths
7
10
UPDATED_FIELD
stringclasses
13 values
REPLACED_VALUE
stringlengths
1
912
REPLACEMENT_VALUE
stringlengths
1
910
NOTES
stringclasses
19 values
2,023
C523798
NM
1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho(2,3-d)imidazolium
sepantronium
Preferred Term (NM) updated on an scr
2,023
C523798
NO
a survivin suppressant with antineoplastic activity; structure in first source
a survivin suppressant with antineoplastic activity
Note updated on a SCR
2,023
C523802
NO
structure in first source
a macrocyclic polymer compound comprising 5 GLYCOLURIL units with methylene bridges
Note updated on a SCR
2,023
C524407
NM
alpha-gustducin, mouse
GNAT3 protein, mouse
Preferred Term (NM) updated on an scr
2,023
C524407
NO
regulates secretion of glucagon-like peptide-1; a taste G protein; GenBank AC129572
RefSeq NM_001081143
Note updated on a SCR
2,023
C524761
NM
leucine carboxyl methyltransferase-1, human
LCMT1 protein, human
Preferred Term (NM) updated on an scr
2,023
C524761
NO
necessary for normal progression through mitosis in mammalian cells; RefSeq NM_001032391.1; NP_001027563.1
necessary for normal progression through mitosis in mammalian cells; RefSeq NM_016309
Note updated on a SCR
2,023
C525638
NM
Hbo1 protein, mouse
Kat7 protein, mouse
Preferred Term (NM) updated on an scr
2,023
C525638
NO
a subunit of both JADE and ING; required for H4 acetylation; GenBank BC048904
a subunit of both JADE and ING; required for H4 acetylation; RefSeq NM_001195003
Note updated on a SCR
2,023
C526014
NO
GenBank AC118592
RefSeq NM_001081424
Note updated on a SCR
2,023
C526276
NO
GenBank AK027784
RefSeq NM_023915
Note updated on a SCR
2,023
C526464
NM
diacylglycerol kinase epsilon, human
DGKE protein, human
Preferred Term (NM) updated on an scr
2,023
C528327
NM
Fedratinib
fedratinib
Preferred Term (NM) updated on an scr
2,023
C529380
NM
sestrin 2 protein, mouse
Sesn2 protein, mouse
Preferred Term (NM) updated on an scr
2,023
C529873
NO
influences nuclear envelope morphology; has been sequenced
RefSeq NM_001183919.1
Note updated on a SCR
2,023
C531059
NM
sestrin 1 protein, mouse
Sesn1 protein, mouse
Preferred Term (NM) updated on an scr
2,023
C531059
NO
GenBank BC055753
RefSeq NM_001162908
Note updated on a SCR
2,023
C531360
NM
SRp75 protein, mouse
Srsf4 protein, mouse
Preferred Term (NM) updated on an scr
2,023
C531360
NO
GenBank AK075769
RefSeq NM_001369308
Note updated on a SCR
2,023
C532667
NM
MURC protein, mouse
Cavin4 protein, mouse
Preferred Term (NM) updated on an scr
2,023
C534481
RN
0
EC 2.3.2.27
Registry number updated on an SCR
2,023
C535877
NO
Broad terminal phalanges of the thumbs and great toes, antimongoloid slant of the palpebral fissures, and characteristic beaked noses
Broad terminal phalanges of the thumbs and great toes, a slant of the palpebral fissures, and characteristic beaked noses
Note updated on a SCR
2,023
C536281
NM
Idiopathic pulmonary hemosiderosis
idiopathic pulmonary hemosiderosis
Preferred Term (NM) updated on an scr
2,023
C536281
NO
A rare disorder characterized by the triad of HEMOPTYSIS, IRON-DEFICIENCY ANEMIA, and transient pulmonary infiltrates observed by RADIOGRAPHY. The underlying disease mechanism is a propensity to recurrent intrapulmonary hemorrhage. Even though large amounts of iron are laid down in the lung, with normal or increased total body iron, anemia occurs because of inability of the erythron to use iron sequestered in pulmonary MACROPHAGES. RESPIRATORY INSUFFICENCY may result from PULMONARY FIBROSIS in advanced cases. OMIM: 178550
A rare disorder characterized by the triad of HEMOPTYSIS; IRON-DEFICIENCY ANEMIA, and diffuse pulmonary hemorrhage as seen as transient pulmonary infiltrates on RADIOGRAPHY. The underlying disease mechanism is a propensity to recurrent intrapulmonary hemorrhage. Even though large amounts of iron are laid down in the lung, with normal or increased total body iron, anemia occurs because of inability of the erythron to use iron sequestered in pulmonary MACROPHAGES. RESPIRATORY INSUFFICIENCY may result from PULMONARY FIBROSIS in advanced cases. OMIM: 178550
Note updated on a SCR
2,023
C536281
SY
Alveolar hypoventilation syndrome
alveolar hypoventilation syndrome
Synonym updated on an scr
2,023
C537118
NO
Short stature, mongoloid facies, short spadelike hands, broad thumbs, genu recurvatum, thick palmar and forearm fasciae, shuffling short-stepped gait
Short stature, facies, short spadelike hands, broad thumbs, genu recurvatum, thick palmar and forearm fasciae, shuffling short-stepped gait
Note updated on a SCR
2,023
C540817
NO
used to treat chronic obstructive pulmonary disease
used to treat chronic obstructive pulmonary disease; combined extracts of Scutellaria baicalensis Georgi, Lonicera japonica flos, Fructus Forsythiae, Pulvis Fellis Ursi and Cornu Saigae Tataricae. Major compounds are Baicalein, ursodeoxycholic acid, chenodeoxycholic acid, forsythin and chlorogenic acid
Note updated on a SCR
2,023
C540817
SO
Zhongguo Zhong Yao Za Zhi 2009 Jan;34(1):104-6
J Ethnopharmacol . 2011 Mar 8;134(1):165-70.
Source updated on a SCR
2,023
C540933
NO
putative biomarker for head and neck squamous cell carcinoma; has been sequenced
RefSeq NR_029867
Note updated on a SCR
2,023
C541037
NM
PogZ protein, human
POGZ protein, human
Preferred Term (NM) updated on an scr
2,023
C541037
NO
GenBank AB007930
RefSeq NM_207171
Note updated on a SCR
2,023
C541037
RN
EC 2.7.7.-
0
Registry number updated on an SCR
2,023
C541529
NO
isolated from Glycyrrhiza inflata; inhibits phosphorylation of NF-kappaB p65 in LPS signaling pathway; structure in first source
isolated from Glycyrrhiza inflata; inhibits phosphorylation of NF-kappaB p65 in LPS signaling pathway
Note updated on a SCR
2,023
C541689
NM
Puf-A protein, mouse
Pum3 protein, mouse
Preferred Term (NM) updated on an scr
2,023
C541689
NO
has been sequenced
RefSeq NM_177474
Note updated on a SCR
2,023
C542157
NM
phospholipase D3, mouse
Pld3 protein, mouse
Preferred Term (NM) updated on an scr
2,023
C542157
NO
GenBank AF026124
RefSeq NM_001317355
Note updated on a SCR
2,023
C543351
NO
RefSeq NW_923574.1; NT_007933.15
RefSeq NR_029498
Note updated on a SCR
2,023
C545185
RN
0
KK8645V7LE
Registry number updated on an SCR
2,023
C546275
NM
MIRN513 microRNA, human
MIRN513A1 microRNA, human
Preferred Term (NM) updated on an scr
2,023
C548820
NM
kalirin protein, mouse
KALRN protein, mouse
Preferred Term (NM) updated on an scr
2,023
C548820
NO
GenBank BC157950
RefSeq XM_011245951
Note updated on a SCR
2,023
C549101
NM
SESN3 protein, mouse
Sesn3 protein, mouse
Preferred Term (NM) updated on an scr
2,023
C550357
NM
6-cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-(1,2,4)triazolo(1,5-a)pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one
filibuvir
Preferred Term (NM) updated on an scr
2,023
C550357
NO
inhibits HCV RNA replicase; structure in first source
inhibits HCV RNA replicase
Note updated on a SCR
2,023
C552705
NO
an adrenergic beta2 receptor agonist; structure in first source
an adrenergic beta2 receptor agonist
Note updated on a SCR
2,023
C552705
RN
0
ZH5SMU97AJ
Registry number updated on an SCR
2,023
C552705
SY
PF 610355
PF-00610355
Synonym updated on an scr
2,023
C553360
NO
an antineoplastic agent and tyrosine kinase inhibitor; structure in first source
an antineoplastic agent and tyrosine kinase inhibitor
Note updated on a SCR
2,023
C553360
SY
HH-GV-678
HH-GV678
Synonym updated on an scr
2,023
C555691
NM
ANAC089 protein, Arabidopsis
AT5G22290 protein, Arabidopsis
Preferred Term (NM) updated on an scr
2,023
C556917
NO
structure in first source; a beta-secretase inhibitor
a beta-secretase inhibitor
Note updated on a SCR
2,023
C557933
NM
AMG 837
AMG-837
Preferred Term (NM) updated on an scr
2,023
C557933
NO
GPR40 agonist; structure in first source
GPR40 agonist
Note updated on a SCR
2,023
C557933
RN
0
NE6U6R66U4
Registry number updated on an SCR
2,023
C558424
NM
UGA1 protein, S. cerevisiae
UGA1 protein, S cerevisiae
Preferred Term (NM) updated on an scr
2,023
C567958
NM
pinkbar protein, mouse
Baiap2l2 protein, mouse
Preferred Term (NM) updated on an scr
2,023
C567958
NO
an I-BAR domain-containing protein expressed in intestinal epithelial cells
an I-BAR domain-containing protein expressed in intestinal epithelial cells; RefSeq NM_177580
Note updated on a SCR
2,023
C568792
NM
spingosine-1-phosphate receptor 4, mouse
sphingosine-1-phosphate receptor 4, mouse
Preferred Term (NM) updated on an scr
2,023
C569389
NM
MIRN195 microRNA, mouse
MIRN195a microRNA, mouse
Preferred Term (NM) updated on an scr
2,023
C569762
NM
PF 03715455
N-(1-(3-chloro-4-hydroxyphenyl)-3-(1,1-dimethylethyl)-1H-pyrazol-5-yl)-N'-((2-((3-(2-((2-hydroxyethyl)thio)phenyl)-1,2,4-triazolo(4,3-a)pyridin-6-yl)thio)phenyl)methyl)-urea
Preferred Term (NM) updated on an scr
2,023
C569762
RN
0
0TJ631J0KP
Registry number updated on an SCR
2,023
C570847
NM
ligand of Numb protein X2, human
Lnx2 protein, human
Preferred Term (NM) updated on an scr
2,023
C570847
NO
GenBank BC036755
RefSeq NM_153371
Note updated on a SCR
2,023
C571179
NO
has antibacterial activity; structure in first source
has antibacterial activity
Note updated on a SCR
2,023
C571179
SY
xerava
Xerava
Synonym updated on an scr
2,023
C571890
NO
a non-structural protein 5B polymerase inhibitor; structure in first source
a non-structural protein 5B polymerase inhibitor
Note updated on a SCR
2,023
C572449
NO
an mTOR inhibitor; structure in first source
an mTOR inhibitor
Note updated on a SCR
2,023
C572689
NM
CAMTA3 protein, Arabidopsis
AT2G22300 protein, Arabidopsis
Preferred Term (NM) updated on an scr
2,023
C573268
NM
glomalin, Mycorrhizae
glomalin
Preferred Term (NM) updated on an scr
2,023
C573580
NO
inhibits microglial activation and improves outcome after central nervous system injury in adult mice
glucosylceramide synthase (GCS) inhibitor
Note updated on a SCR
2,023
C573580
RN
0
CY416F5NSK
Registry number updated on an SCR
2,023
C574123
NO
pregnane X receptor/PXR activator; structure in first source
pregnane X receptor/PXR activator
Note updated on a SCR
2,023
C574123
RN
0
7CC5CL28DK
Registry number updated on an SCR
2,023
C575263
RN
0
CCP2U6LWTP
Registry number updated on an SCR
2,023
C576790
NO
inner nuclear membrane protein
RefSeq NM_001020342.2
Note updated on a SCR
2,023
C578009
NO
has antiviral activity
has antiviral activity; component of Zepatier
Note updated on a SCR
2,023
C578454
NO
RefSeq XM_574558
RefSeq XM_039094638
Note updated on a SCR
2,023
C578787
NO
a deubiquitinase
RefSeq NM_001025613
Note updated on a SCR
2,023
C578787
RN
EC 3.4.-
EC 3.4.19.12
Registry number updated on an SCR
2,023
C579813
NM
3-((1H-pyrazolo(3,4-b)pyridin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
olverembatinib
Preferred Term (NM) updated on an scr
2,023
C579813
NO
inhibits Bcr-Abl kinase to overcome imatinb resistance; structure in first source
inhibits Bcr-Abl kinase to overcome imatinb resistance
Note updated on a SCR
2,023
C579813
RN
0
KV1M7Q3CBP
Registry number updated on an SCR
2,023
C580661
NM
RabE1c protein, Arabidopsis
AT3G46060 protein, Arabidopsis
Preferred Term (NM) updated on an scr
2,023
C582345
NO
in phase I clinical trials for treatment of systemic sclerosis; directed against type I IFN-alpha receptor
directed against type I IFN-alpha receptor
Note updated on a SCR
2,023
C582883
RN
Ec 1.-
EC 1.-
Registry number updated on an SCR
2,023
C583533
NM
Lerepo4 protein, human
ZC3H15 protein, human
Preferred Term (NM) updated on an scr
2,023
C583620
NO
Steap4 - Six-transmembrane Epithelial Antigen of the Prostate 4; a ferri/cuprireductase; GenBank BC097353
RefSeq NM_001044265
Note updated on a SCR
2,023
C586092
NM
phospholipase D3, human
PLD3 protein, human
Preferred Term (NM) updated on an scr
2,023
C587926
NM
Gm129 protein, mouse
Ciart protein, mouse
Preferred Term (NM) updated on an scr
2,023
C588365
NM
BARK1 protein, Arabidopsis
AT3g23750 protein, Arabidopsis
Preferred Term (NM) updated on an scr
2,023
D000069980
MH
Lactobacillus paracasei
Lacticaseibacillus paracasei
Preferred Term (MH) updated on a descriptor
2,023
D000069996
HN
2023; use LACTOBACILLUS SALIVARIUS 2017-2022
2023(2017)
History note updated on a descriptor
2,023
D000069996
MH
Lactobacillus salivarius
Ligilactobacillus salivarius
Preferred Term (MH) updated on a descriptor
2,023
D000069996
PM
2023(2017)
2023; see LACTOBACILLUS SALIVARIUS 2017-2022
public MeSH note updated on a descriptor
2,023
D000070256
HN
2023; was LACTOBACILLUS SAKEI 2017-2022
2023(2017)
History note updated on a descriptor
2,023
D000070256
MH
Lactobacillus sakei
Latilactobacillus sakei
Preferred Term (MH) updated on a descriptor
2,023
D000070256
PM
2023; was LACTOBACILLUS SAKEI 2017-2022
2023; see LACTOBACILLUS SAKEI 2017-2022
public MeSH note updated on a descriptor
2,023
D000070380
MH
Xanthorrhoeaceae
Asphodelaceae
Preferred Term (MH) updated on a descriptor
2,023
D000073359
MH
Whole Exome Sequencing
Exome Sequencing
Preferred Term (MH) updated on a descriptor